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Correction to: BRADSHAW: a system for automated molecular design.

Green DVS, Pickett S, Luscombe C, Senger S, Marcus D, Meslamani J, Brett D, Powell A, Masson J.

J Comput Aided Mol Des. 2019 Nov 6. doi: 10.1007/s10822-019-00243-7. [Epub ahead of print]


Is plasma renin activity associated with worse outcomes in acute heart failure? A secondary analysis from the BLAST-AHF trial.

Rachwan RJ, Butler J, Collins SP, Cotter G, Davison BA, Senger S, Ezekowitz JA, Filippatos G, Levy PD, Metra M, Ponikowski P, Teerlink JR, Voors AA, de Boer RA, Soergel DG, Felker GM, Pang PS.

Eur J Heart Fail. 2019 Oct 23. doi: 10.1002/ejhf.1607. [Epub ahead of print]


BRADSHAW: a system for automated molecular design.

Green DVS, Pickett S, Luscombe C, Senger S, Marcus D, Meslamani J, Brett D, Powell A, Masson J.

J Comput Aided Mol Des. 2019 Oct 21. doi: 10.1007/s10822-019-00234-8. [Epub ahead of print] Erratum in: J Comput Aided Mol Des. 2019 Nov 6;:.


The extended endoscopic approach to perisellar and skull base lesions: is one nostril enough?

Oertel J, Senger S, Linsler S.

Neurosurg Rev. 2019 Sep 16. doi: 10.1007/s10143-019-01171-8. [Epub ahead of print]


Loss of consciousness at onset of aneurysmal subarachnoid hemorrhage in good-grade patients.

Hendrix P, Foreman PM, Senger S, Burkhardt BW, Harrigan MR, Fisher WS 3rd, Vyas NA, Lipsky RH, Walters BC, Tubbs RS, Shoja MM, Griessenauer CJ.

Neurosurg Rev. 2019 Jul 22. doi: 10.1007/s10143-019-01142-z. [Epub ahead of print]


Human gut derived-organoids provide model to study gluten response and effects of microbiota-derived molecules in celiac disease.

Freire R, Ingano L, Serena G, Cetinbas M, Anselmo A, Sapone A, Sadreyev RI, Fasano A, Senger S.

Sci Rep. 2019 May 7;9(1):7029. doi: 10.1038/s41598-019-43426-w.


Imaging of Microhemodynamics in Peripheral Nerves by Contact Endoscope.

Senger S, Keiner D, Schwerdtfeger K, Oertel J.

World Neurosurg. 2019 Jun;126:e1302-e1308. doi: 10.1016/j.wneu.2019.03.081. Epub 2019 Mar 18.


Explicit interaction information from WikiPathways in RDF facilitates drug discovery in the Open PHACTS Discovery Platform.

Miller RA, Woollard P, Willighagen EL, Digles D, Kutmon M, Loizou A, Waagmeester A, Senger S, Evelo CT.

Version 2. F1000Res. 2018 Jan 17 [revised 2018 Jan 1];7:75. doi: 10.12688/f1000research.13197.2. eCollection 2018.


Bacteriophage Therapy Testing Against Shigella flexneri in a Novel Human Intestinal Organoid-Derived Infection Model.

Llanos-Chea A, Citorik RJ, Nickerson KP, Ingano L, Serena G, Senger S, Lu TK, Fasano A, Faherty CS.

J Pediatr Gastroenterol Nutr. 2019 Apr;68(4):509-516. doi: 10.1097/MPG.0000000000002203.


Management of severe intraoperative hemorrhage during intraventricular neuroendoscopic procedures: the dry field technique.

Oertel J, Linsler S, Csokonay A, Schroeder HWS, Senger S.

J Neurosurg. 2018 Sep 21;131(3):931-935. doi: 10.3171/2018.4.JNS172537.


The effects of reduced hemodynamic loading on morphogenesis of the mouse embryonic heart.

Hoog TG, Fredrickson SJ, Hsu CW, Senger SM, Dickinson ME, Udan RS.

Dev Biol. 2018 Oct 1;442(1):127-137. doi: 10.1016/j.ydbio.2018.07.007. Epub 2018 Jul 17.


A Double-Blind Placebo-Controlled Trial of Omega-3 Fatty Acids as a Monotherapy for Adolescent Depression.

Gabbay V, Freed RD, Alonso CM, Senger S, Stadterman J, Davison BA, Klein RG.

J Clin Psychiatry. 2018 Jun 26;79(4). pii: 17m11596. doi: 10.4088/JCP.17m11596.


[The use of Idarucizumab in intracerebral bleeding - a case report].

Hummel BA, Senger S, Schleicher C, Eichler H.

Dtsch Med Wochenschr. 2018 Jul;113(13):961-964. doi: 10.1055/a-0620-7459. Epub 2018 Jul 4. German.


Human Fetal-Derived Enterospheres Provide Insights on Intestinal Development and a Novel Model to Study Necrotizing Enterocolitis (NEC).

Senger S, Ingano L, Freire R, Anselmo A, Zhu W, Sadreyev R, Walker WA, Fasano A.

Cell Mol Gastroenterol Hepatol. 2018 Jan 31;5(4):549-568. doi: 10.1016/j.jcmgh.2018.01.014. eCollection 2018.


Visualization and Identification of the Pituitary Gland Tissue in Endonasal Pituitary Surgery: Is There a Difference Between High-Definition Endoscopy and Microscopy?

Linsler S, Szameitat N, Senger S, Oertel J.

World Neurosurg. 2018 Aug;116:e921-e928. doi: 10.1016/j.wneu.2018.05.129. Epub 2018 May 28.


Prognostic Significance of Creatinine Increases During an Acute Heart Failure Admission in Patients With and Without Residual Congestion: A Post Hoc Analysis of the PROTECT Data.

Metra M, Cotter G, Senger S, Edwards C, Cleland JG, Ponikowski P, Cursack GC, Milo O, Teerlink JR, Givertz MM, O'Connor CM, Dittrich HC, Bloomfield DM, Voors AA, Davison BA.

Circ Heart Fail. 2018 May;11(5):e004644. doi: 10.1161/CIRCHEARTFAILURE.117.004644.


Salmonella Typhi Colonization Provokes Extensive Transcriptional Changes Aimed at Evading Host Mucosal Immune Defense During Early Infection of Human Intestinal Tissue.

Nickerson KP, Senger S, Zhang Y, Lima R, Patel S, Ingano L, Flavahan WA, Kumar DKV, Fraser CM, Faherty CS, Sztein MB, Fiorentino M, Fasano A.

EBioMedicine. 2018 May;31:92-109. doi: 10.1016/j.ebiom.2018.04.005. Epub 2018 Apr 12.


The endoscopic surgical resection of intrasellar lesions conserves the hormonal function: a negative correlation to the microsurgical technique.

Linsler S, Senger S, Hero-Gross R, Steudel WI, Oertel J.

J Neurosurg Sci. 2018 Mar 28. doi: 10.23736/S0390-5616.18.04242-X. [Epub ahead of print]


Promoter methylation of RB1, P15, P16, and MGMT and their impact on the clinical course of pilocytic astrocytomas.

Sippl C, Urbschat S, Kim YJ, Senger S, Oertel J, Ketter R.

Oncol Lett. 2018 Feb;15(2):1600-1606. doi: 10.3892/ol.2017.7490. Epub 2017 Nov 24.


The view through the ventricle catheter - The new ShuntScope for the therapy of pediatric hydrocephalus.

Senger S, Antes S, Salah M, Tschan C, Linsler S, Oertel J.

J Clin Neurosci. 2018 Feb;48:196-202. doi: 10.1016/j.jocn.2017.10.046. Epub 2017 Nov 6.


Preoperative Navigated Transcranial Magnetic Stimulation and Tractography to Guide Endoscopic Cystoventriculostomy: A Technical Note and Case Report.

Hendrix P, Senger S, Griessenauer CJ, Simgen A, Linsler S, Oertel J.

World Neurosurg. 2018 Jan;109:209-217. doi: 10.1016/j.wneu.2017.09.185. Epub 2017 Oct 5.


Relationship between baseline systolic blood pressure and long-term outcomes in acute heart failure patients treated with TRV027: an exploratory subgroup analysis of BLAST-AHF.

Cotter G, Davison BA, Butler J, Collins SP, Ezekowitz JA, Felker GM, Filippatos G, Levy PD, Metra M, Ponikowski P, Teerlink JR, Voors AA, Senger S, Bharucha D, Goin K, Soergel DG, Pang PS.

Clin Res Cardiol. 2018 Feb;107(2):170-181. doi: 10.1007/s00392-017-1168-0. Epub 2017 Oct 6.


Results of Combined Intraventricular Neuroendoscopic Procedures in 130 Cases with Special Focus on Fornix Contusions.

Oertel J, Linsler S, Emmerich C, Keiner D, Gaab M, Schroeder H, Senger S.

World Neurosurg. 2017 Dec;108:817-825. doi: 10.1016/j.wneu.2017.09.045. Epub 2017 Sep 18.


Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe?

Cotter G, Metra M, Davison BA, Jondeau G, Cleland JGF, Bourge RC, Milo O, O'Connor CM, Parker JD, Torre-Amione G, van Veldhuisen DJ, Kobrin I, Rainisio M, Senger S, Edwards C, McMurray JJV, Teerlink JR; VERITAS Investigators.

Eur J Heart Fail. 2018 Feb;20(2):317-322. doi: 10.1002/ejhf.889. Epub 2017 Sep 4.


Intra-catheter endoscopy for various shunting procedures-a retrospective analysis on surgical practicability, catheter placement, and failure rates.

Antes S, Linsler S, Salah M, Senger S, Oertel J.

Acta Neurochir (Wien). 2017 Oct;159(10):1991-1998. doi: 10.1007/s00701-017-3264-3. Epub 2017 Jul 10.


Portal branch ligation does not counteract the inhibiting effect of temsirolimus on extrahepatic colorectal metastatic growth.

Senger S, Sperling J, Oberkircher B, Schilling MK, Kollmar O, Menger MD, Ziemann C.

Clin Exp Metastasis. 2017 Jun;34(5):323-332. doi: 10.1007/s10585-017-9852-z. Epub 2017 Jun 19.


HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche.

Xian L, Georgess D, Huso T, Cope L, Belton A, Chang YT, Kuang W, Gu Q, Zhang X, Senger S, Fasano A, Huso DL, Ewald AJ, Resar LMS.

Nat Commun. 2017 Apr 28;8:15008. doi: 10.1038/ncomms15008.


In Reply to "New Oral Anticoagulants and Pituitary Apoplexy".

Senger S, Linsler S.

World Neurosurg. 2017 Apr;100:701. doi: 10.1016/j.wneu.2017.01.050. No abstract available.


Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure-does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Studies (VERITAS).

Cleland JGF, Teerlink JR, Davison BA, Shoaib A, Metra M, Senger S, Milo O, Cotter G, Bourge RC, Parker JD, Jondeau G, Krum H, O'Connor CM, Torre-Amione G, van Veldhuisen DJ, McMurray JJV; VERITAS Investigators.

Eur J Heart Fail. 2017 Jun;19(6):739-747. doi: 10.1002/ejhf.786. Epub 2017 Mar 10.


Preoperative navigated transcranial magnetic stimulation and tractography in transparietal approach to the trigone of the lateral ventricle.

Hendrix P, Senger S, Griessenauer CJ, Simgen A, Linsler S, Oertel J.

J Clin Neurosci. 2017 Jul;41:154-161. doi: 10.1016/j.jocn.2017.02.029. Epub 2017 Mar 9.


Endoscopic-Assisted Burr Hole Reservoir and Ventricle Catheter Placement.

Antes S, Tschan CA, Heckelmann M, Salah M, Senger S, Linsler S, Oertel J.

World Neurosurg. 2017 May;101:11-19. doi: 10.1016/j.wneu.2017.01.095. Epub 2017 Feb 4.


Preoperative rTMS Language Mapping in Speech-Eloquent Brain Lesions Resected Under General Anesthesia: A Pair-Matched Cohort Study.

Hendrix P, Senger S, Simgen A, Griessenauer CJ, Oertel J.

World Neurosurg. 2017 Apr;100:425-433. doi: 10.1016/j.wneu.2017.01.041. Epub 2017 Jan 19.


Blood-brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders.

Fiorentino M, Sapone A, Senger S, Camhi SS, Kadzielski SM, Buie TM, Kelly DL, Cascella N, Fasano A.

Mol Autism. 2016 Nov 29;7:49. eCollection 2016.


Comparison of Muscle Involvement and Posture Between the Conventional Deadlift and a "Walk-In" Style Deadlift Machine.

Snyder BJ, Cauthen CP, Senger SR.

J Strength Cond Res. 2017 Oct;31(10):2859-2865. doi: 10.1519/JSC.0000000000001723.


Open PHACTS computational protocols for in silico target validation of cellular phenotypic screens: knowing the knowns.

Digles D, Zdrazil B, Neefs JM, Van Vlijmen H, Herhaus C, Caracoti A, Brea J, Roibás B, Loza MI, Queralt-Rosinach N, Furlong LI, Gaulton A, Bartek L, Senger S, Chichester C, Engkvist O, Evelo CT, Franklin NI, Marren D, Ecker GF, Jacoby E.

Medchemcomm. 2016 Jun 1;7(6):1237-1244. Epub 2016 May 11.


In-hospital worsening heart failure in patients admitted for acute heart failure.

Carubelli V, Cotter G, Davison B, Gishe J, Senger S, Bonadei I, Gorga E, Lazzarini V, Lombardi C, Metra M.

Int J Cardiol. 2016 Dec 15;225:353-361. doi: 10.1016/j.ijcard.2016.10.002. Epub 2016 Oct 5.


Preoperative navigated transcranial magnetic stimulation in patients with motor eloquent lesions with emphasis on metastasis.

Hendrix P, Senger S, Griessenauer CJ, Simgen A, Schwerdtfeger K, Oertel J.

Clin Anat. 2016 Oct;29(7):925-31. doi: 10.1002/ca.22765. Epub 2016 Aug 23.


Patient journey after admission for acute heart failure: length of stay, 30-day readmission and 90-day mortality.

Davison BA, Metra M, Senger S, Edwards C, Milo O, Bloomfield DM, Cleland JG, Dittrich HC, Givertz MM, O'Connor CM, Massie BM, Ponikowski P, Teerlink JR, Voors AA, Cotter G.

Eur J Heart Fail. 2016 Aug;18(8):1041-50. doi: 10.1002/ejhf.540. Epub 2016 Apr 25.


Sulforaphane Preconditioning Sensitizes Human Colon Cancer Cells towards the Bioreductive Anticancer Prodrug PR-104A.

Erzinger MM, Bovet C, Hecht KM, Senger S, Winiker P, Sobotzki N, Cristea S, Beerenwinkel N, Shay JW, Marra G, Wollscheid B, Sturla SJ.

PLoS One. 2016 Mar 7;11(3):e0150219. doi: 10.1371/journal.pone.0150219. eCollection 2016.


New Target-Specific Oral Anticoagulants and Intracranial Bleeding: Management and Outcome in a Single-Center Case Series.

Senger S, Keiner D, Hendrix P, Oertel J.

World Neurosurg. 2016 Apr;88:132-139. doi: 10.1016/j.wneu.2015.11.086. Epub 2015 Dec 28.


Superficial Temporal Artery to Middle Cerebral Artery Bypass via a Minimized Approach: Operative Nuances and Problem-Solving Aspects.

Fischer G, Senger S, Sharif S, Oertel J.

World Neurosurg. 2016 Apr;88:97-103. doi: 10.1016/j.wneu.2015.12.029. Epub 2015 Dec 28.


Predictors and Associations With Outcomes of Length of Hospital Stay in Patients With Acute Heart Failure: Results From VERITAS.

Cotter G, Davison BA, Milo O, Bourge RC, Cleland JG, Jondeau G, Krum H, O'Connor CM, Metra M, Parker JD, Torre-Amione G, van Veldhuisen DJ, Kobrin I, Rainisio M, Senger S, Edwards C, McMurray JJ, Teerlink JR; VERITAS Investigators.

J Card Fail. 2016 Oct;22(10):815-22. doi: 10.1016/j.cardfail.2015.12.017. Epub 2015 Dec 22.


Darbepoetin-α Promotes Cell Proliferation in Established Extrahepatic Colorectal Tumors after Major Hepatectomy.

Senger S, Kollmar O, Menger MD, Rupertus K.

Eur Surg Res. 2016;56(1-2):49-60. doi: 10.1159/000442384. Epub 2015 Dec 18. Erratum in: Eur Surg Res. 2016;56(3-4):180.


Celiac Disease Histopathology Recapitulates Hedgehog Downregulation, Consistent with Wound Healing Processes Activation.

Senger S, Sapone A, Fiorentino MR, Mazzarella G, Lauwers GY, Fasano A.

PLoS One. 2015 Dec 9;10(12):e0144634. doi: 10.1371/journal.pone.0144634. eCollection 2015.


Managing expectations: assessment of chemistry databases generated by automated extraction of chemical structures from patents.

Senger S, Bartek L, Papadatos G, Gaulton A.

J Cheminform. 2015 Oct 6;7(1):49. eCollection 2015 Dec.


The application of the open pharmacological concepts triple store (open PHACTS) to support drug discovery research.

Ratnam J, Zdrazil B, Digles D, Cuadrado-Rodriguez E, Neefs JM, Tipney H, Siebes R, Waagmeester A, Bradley G, Chau CH, Richter L, Brea J, Evelo CT, Jacoby E, Senger S, Loza MI, Ecker GF, Chichester C.

PLoS One. 2014 Dec 18;9(12):e115460. doi: 10.1371/journal.pone.0115460. eCollection 2014.


TORC1 regulators Iml1/GATOR1 and GATOR2 control meiotic entry and oocyte development in Drosophila.

Wei Y, Reveal B, Reich J, Laursen WJ, Senger S, Akbar T, Iida-Jones T, Cai W, Jarnik M, Lilly MA.

Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):E5670-7. doi: 10.1073/pnas.1419156112. Epub 2014 Dec 15.


Worsening heart failure, a critical event during hospital admission for acute heart failure: results from the VERITAS study.

Cotter G, Metra M, Davison BA, Senger S, Bourge RC, Cleland JG, Jondeau G, Krum H, O'Connor CM, Parker JD, Torre-Amione G, van Veldhuisen DJ, Milo O, Kobrin I, Rainisio M, McMurray JJ, Teerlink JR; VERITAS Investigators.

Eur J Heart Fail. 2014 Dec;16(12):1362-71. doi: 10.1002/ejhf.186. Epub 2014 Nov 5.

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