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Items: 17


PDEF is a negative regulator of colon cancer cell growth and migration.

Moussa O, Turner DP, Feldman RJ, Sementchenko VI, McCarragher BD, Desouki MM, Fraig M, Watson DK.

J Cell Biochem. 2009 Dec 15;108(6):1389-98. doi: 10.1002/jcb.22371.


Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm.

Li XY, MacArthur S, Bourgon R, Nix D, Pollard DA, Iyer VN, Hechmer A, Simirenko L, Stapleton M, Luengo Hendriks CL, Chu HC, Ogawa N, Inwood W, Sementchenko V, Beaton A, Weiszmann R, Celniker SE, Knowles DW, Gingeras T, Speed TP, Eisen MB, Biggin MD.

PLoS Biol. 2008 Feb;6(2):e27. doi: 10.1371/journal.pbio.0060027.


RNA maps reveal new RNA classes and a possible function for pervasive transcription.

Kapranov P, Cheng J, Dike S, Nix DA, Duttagupta R, Willingham AT, Stadler PF, Hertel J, Hackerm├╝ller J, Hofacker IL, Bell I, Cheung E, Drenkow J, Dumais E, Patel S, Helt G, Ganesh M, Ghosh S, Piccolboni A, Sementchenko V, Tammana H, Gingeras TR.

Science. 2007 Jun 8;316(5830):1484-8. Epub 2007 May 17.


Transcriptional landscape of the human and fly genomes: nonlinear and multifunctional modular model of transcriptomes.

Willingham AT, Dike S, Cheng J, Manak JR, Bell I, Cheung E, Drenkow J, Dumais E, Duttagupta R, Ganesh M, Ghosh S, Helt G, Nix D, Piccolboni A, Sementchenko V, Tammana H, Kapranov P; ENCODE Genes And Transcripts Group, Gingeras TR.

Cold Spring Harb Symp Quant Biol. 2006;71:101-10.


Genome-wide analysis of estrogen receptor binding sites.

Carroll JS, Meyer CA, Song J, Li W, Geistlinger TR, Eeckhoute J, Brodsky AS, Keeton EK, Fertuck KC, Hall GF, Wang Q, Bekiranov S, Sementchenko V, Fox EA, Silver PA, Gingeras TR, Liu XS, Brown M.

Nat Genet. 2006 Nov;38(11):1289-97. Epub 2006 Oct 1.


Biological function of unannotated transcription during the early development of Drosophila melanogaster.

Manak JR, Dike S, Sementchenko V, Kapranov P, Biemar F, Long J, Cheng J, Bell I, Ghosh S, Piccolboni A, Gingeras TR.

Nat Genet. 2006 Oct;38(10):1151-8. Epub 2006 Sep 3.


Comprehensive identification of Drosophila dorsal-ventral patterning genes using a whole-genome tiling array.

Biemar F, Nix DA, Piel J, Peterson B, Ronshaugen M, Sementchenko V, Bell I, Manak JR, Levine MS.

Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12763-8. Epub 2006 Aug 14.


Spatial regulation of microRNA gene expression in the Drosophila embryo.

Biemar F, Zinzen R, Ronshaugen M, Sementchenko V, Manak JR, Levine MS.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15907-11. Epub 2005 Oct 25.


Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution.

Cheng J, Kapranov P, Drenkow J, Dike S, Brubaker S, Patel S, Long J, Stern D, Tammana H, Helt G, Sementchenko V, Piccolboni A, Bekiranov S, Bailey DK, Ganesh M, Ghosh S, Bell I, Gerhard DS, Gingeras TR.

Science. 2005 May 20;308(5725):1149-54. Epub 2005 Mar 24.


SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion.

Yordy JS, Li R, Sementchenko VI, Pei H, Muise-Helmericks RC, Watson DK.

Oncogene. 2004 Aug 26;23(39):6654-65.


Beyond expression profiling: next generation uses of high density oligonucleotide arrays.

Kapranov P, Sementchenko VI, Gingeras TR.

Brief Funct Genomic Proteomic. 2003 Apr;2(1):47-56. Review.


Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs.

Cawley S, Bekiranov S, Ng HH, Kapranov P, Sekinger EA, Kampa D, Piccolboni A, Sementchenko V, Cheng J, Williams AJ, Wheeler R, Wong B, Drenkow J, Yamanaka M, Patel S, Brubaker S, Tammana H, Helt G, Struhl K, Gingeras TR.

Cell. 2004 Feb 20;116(4):499-509.


Pdef expression in human breast cancer is correlated with invasive potential and altered gene expression.

Feldman RJ, Sementchenko VI, Gayed M, Fraig MM, Watson DK.

Cancer Res. 2003 Aug 1;63(15):4626-31.


The epithelial-specific Ets factors occupy a unique position in defining epithelial proliferation, differentiation and carcinogenesis.

Feldman RJ, Sementchenko VI, Watson DK.

Anticancer Res. 2003 May-Jun;23(3A):2125-31. Review.


Ets1 is an effector of the transforming growth factor beta (TGF-beta ) signaling pathway and an antagonist of the profibrotic effects of TGF-beta.

Czuwara-Ladykowska J, Sementchenko VI, Watson DK, Trojanowska M.

J Biol Chem. 2002 Jun 7;277(23):20399-408. Epub 2002 Mar 27.


Ets target genes: past, present and future.

Sementchenko VI, Watson DK.

Oncogene. 2000 Dec 18;19(55):6533-48. Review.


ETS2 function is required to maintain the transformed state of human prostate cancer cells.

Sementchenko VI, Schweinfest CW, Papas TS, Watson DK.

Oncogene. 1998 Dec 3;17(22):2883-8.

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