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Items: 1 to 50 of 101


Photon-separation to enhance the spatial resolution of pulsed STED microscopy.

Tortarolo G, Sun Y, Teng KW, Ishitsuka Y, Lanzanó L, Selvin PR, Barbieri B, Diaspro A, Vicidomini G.

Nanoscale. 2019 Jan 23;11(4):1754-1761. doi: 10.1039/c8nr07485b.


A Revised View on the Role of Surface AMPAR Mobility in Tuning Synaptic Transmission: Limitations, Tools, and Alternative Views.

Delgado JY, Selvin PR.

Front Synaptic Neurosci. 2018 Jul 20;10:21. doi: 10.3389/fnsyn.2018.00021. eCollection 2018. Review.


Delivery of Fluorescent Probes Using Streptolysin O for Fluorescence Microscopy of Living Cells.

Teng KW, Ren P, Selvin PR.

Curr Protoc Protein Sci. 2018 Aug;93(1):e60. doi: 10.1002/cpps.60. Epub 2018 Jul 30.


Magnetic Cytoskeleton Affinity Purification of Microtubule Motors Conjugated to Quantum Dots.

Tjioe M, Ryoo H, Ishitsuka Y, Ge P, Bookwalter C, Huynh W, McKenney RJ, Trybus KM, Selvin PR.

Bioconjug Chem. 2018 Jul 18;29(7):2278-2286. doi: 10.1021/acs.bioconjchem.8b00264. Epub 2018 Jul 3.


Thermal nanoimprint lithography for drift correction in super-resolution fluorescence microscopy.

Youn Y, Ishitsuka Y, Jin C, Selvin PR.

Opt Express. 2018 Jan 22;26(2):1670-1680. doi: 10.1364/OE.26.001670.


Correction: Super-resolution imaging of synaptic and Extra-synaptic AMPA receptors with different-sized fluorescent probes.

Lee SH, Jin C, Cai E, Ge P, Ishitsuka Y, Teng KW, de Thomaz AA, Nall D, Baday M, Jeyifous O, Demonte D, Dundas CM, Park S, Delgado JY, Green WN, Selvin PR.

Elife. 2017 Nov 8;6. pii: e33413. doi: 10.7554/eLife.33413. No abstract available.


Super-resolution imaging of synaptic and Extra-synaptic AMPA receptors with different-sized fluorescent probes.

Lee SH, Jin C, Cai E, Ge P, Ishitsuka Y, Teng KW, de Thomaz AA, Nall D, Baday M, Jeyifous O, Demonte D, Dundas CM, Park S, Delgado JY, Green WN, Selvin PR.

Elife. 2017 Jul 27;6. pii: e27744. doi: 10.7554/eLife.27744. Erratum in: Elife. 2017 Nov 08;6:.


Labeling Proteins Inside Living Cells Using External Fluorophores for Fluorescence Microscopy.

Teng KW, Ishitsuka Y, Ren P, Youn Y, Deng X, Ge P, Lee SH, Belmont AS, Selvin PR.

Elife. 2017 Jan 31;6. pii: e25460. doi: 10.7554/eLife.25460. No abstract available.


Label-Free Imaging of Single Microtubule Dynamics Using Spatial Light Interference Microscopy.

Kandel ME, Teng KW, Selvin PR, Popescu G.

ACS Nano. 2017 Jan 24;11(1):647-655. doi: 10.1021/acsnano.6b06945. Epub 2016 Dec 27.


Labeling proteins inside living cells using external fluorophores for microscopy.

Teng KW, Ishitsuka Y, Ren P, Youn Y, Deng X, Ge P, Lee SH, Belmont AS, Selvin PR.

Elife. 2016 Dec 9;5. pii: e20378. doi: 10.7554/eLife.20378. Erratum in: Elife. 2017 Jan 31;6:.


Probing the Heterogeneity of Protein Kinase Activation in Cells by Super-resolution Microscopy.

Zhang R, Fruhwirth GO, Coban O, Barrett JE, Burgoyne T, Lee SH, Simonson PD, Baday M, Kholodenko BN, Futter CE, Ng T, Selvin PR.

ACS Nano. 2017 Jan 24;11(1):249-257. doi: 10.1021/acsnano.6b05356. Epub 2016 Nov 3.


Multidentate Polymer Coatings for Compact and Homogeneous Quantum Dots with Efficient Bioconjugation.

Ma L, Tu C, Le P, Chitoor S, Lim SJ, Zahid MU, Teng KW, Ge P, Selvin PR, Smith AM.

J Am Chem Soc. 2016 Mar 16;138(10):3382-94. doi: 10.1021/jacs.5b12378. Epub 2016 Mar 8.


Small quantum dots conjugated to nanobodies as immunofluorescence probes for nanometric microscopy.

Wang Y, Cai E, Rosenkranz T, Ge P, Teng KW, Lim SJ, Smith AM, Chung HJ, Sachs F, Green WN, Gottlieb P, Selvin PR.

Bioconjug Chem. 2014 Dec 17;25(12):2205-11. doi: 10.1021/bc5004179. Epub 2014 Nov 25.


Fluorescence imaging with one-nanometer accuracy (FIONA).

Wang Y, Cai E, Sheung J, Lee SH, Teng KW, Selvin PR.

J Vis Exp. 2014 Sep 26;(91):51774. doi: 10.3791/51774.


Stable small quantum dots for synaptic receptor tracking on live neurons.

Cai E, Ge P, Lee SH, Jeyifous O, Wang Y, Liu Y, Wilson KM, Lim SJ, Baird MA, Stone JE, Lee KY, Davidson MW, Chung HJ, Schulten K, Smith AM, Green WN, Selvin PR.

Angew Chem Int Ed Engl. 2014 Nov 10;53(46):12484-8. doi: 10.1002/anie.201405735. Epub 2014 Sep 26.


Single-molecule fluorescence and in vivo optical traps: how multiple dyneins and kinesins interact.

Blehm BH, Selvin PR.

Chem Rev. 2014 Mar 26;114(6):3335-52. doi: 10.1021/cr4005555. Epub 2014 Jan 23. Review. No abstract available.


Single molecule FRET reveals pore size and opening mechanism of a mechano-sensitive ion channel.

Wang Y, Liu Y, Deberg HA, Nomura T, Hoffman MT, Rohde PR, Schulten K, Martinac B, Selvin PR.

Elife. 2014 Feb 18;3:e01834. doi: 10.7554/eLife.01834.


3D super-resolution imaging with blinking quantum dots.

Wang Y, Fruhwirth G, Cai E, Ng T, Selvin PR.

Nano Lett. 2013 Nov 13;13(11):5233-41. doi: 10.1021/nl4026665. Epub 2013 Oct 10.


Motor domain phosphorylation modulates kinesin-1 transport.

DeBerg HA, Blehm BH, Sheung J, Thompson AR, Bookwalter CS, Torabi SF, Schroer TA, Berger CL, Lu Y, Trybus KM, Selvin PR.

J Biol Chem. 2013 Nov 8;288(45):32612-21. doi: 10.1074/jbc.M113.515510. Epub 2013 Sep 26.


In vivo optical trapping indicates kinesin's stall force is reduced by dynein during intracellular transport.

Blehm BH, Schroer TA, Trybus KM, Chemla YR, Selvin PR.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3381-6. doi: 10.1073/pnas.1219961110. Epub 2013 Feb 12. Erratum in: Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9613.


Direct detection of adenosine in undiluted serum using a luminescent aptamer sensor attached to a terbium complex.

Li LL, Ge P, Selvin PR, Lu Y.

Anal Chem. 2012 Sep 18;84(18):7852-6. doi: 10.1021/ac302167d. Epub 2012 Aug 28.


Using fixed fiduciary markers for stage drift correction.

Lee SH, Baday M, Tjioe M, Simonson PD, Zhang R, Cai E, Selvin PR.

Opt Express. 2012 May 21;20(11):12177-83. doi: 10.1364/OE.20.012177.


Multicolor super-resolution DNA imaging for genetic analysis.

Baday M, Cravens A, Hastie A, Kim H, Kudeki DE, Kwok PY, Xiao M, Selvin PR.

Nano Lett. 2012 Jul 11;12(7):3861-6. doi: 10.1021/nl302069q. Epub 2012 Jun 18. Erratum in: Nano Lett. 2013 Mar 13;13(3):1365.


Biomimetic surface engineering of lanthanide-doped upconversion nanoparticles as versatile bioprobes.

Li LL, Zhang R, Yin L, Zheng K, Qin W, Selvin PR, Lu Y.

Angew Chem Int Ed Engl. 2012 Jun 18;51(25):6121-5. doi: 10.1002/anie.201109156. Epub 2012 May 8. No abstract available. Erratum in: Angew Chem Int Ed Engl. 2013 Aug 5;52(32):8190.


Single-molecule-based super-resolution images in the presence of multiple fluorophores.

Simonson PD, Rothenberg E, Selvin PR.

Nano Lett. 2011 Nov 9;11(11):5090-6. doi: 10.1021/nl203560r. Epub 2011 Oct 19. Erratum in: Nano Lett. 2013 Mar 13;13(3):1366.


Two-photon 3D FIONA of individual quantum dots in an aqueous environment.

Zhang R, Rothenberg E, Fruhwirth G, Simonson PD, Ye F, Golding I, Ng T, Lopes W, Selvin PR.

Nano Lett. 2011 Oct 12;11(10):4074-8. doi: 10.1021/nl201225r. Epub 2011 Sep 13.


Fluorescence imaging with one nanometer accuracy: in vitro and in vivo studies of molecular motors.

Hoffman MT, Sheung J, Selvin PR.

Methods Mol Biol. 2011;778:33-56. doi: 10.1007/978-1-61779-261-8_4.


Extension of a three-helix bundle domain of myosin VI and key role of calmodulins.

Liu Y, Hsin J, Kim H, Selvin PR, Schulten K.

Biophys J. 2011 Jun 22;100(12):2964-73. doi: 10.1016/j.bpj.2011.05.010.


Single-virus tracking reveals a spatial receptor-dependent search mechanism.

Rothenberg E, Sepúlveda LA, Skinner SO, Zeng L, Selvin PR, Golding I.

Biophys J. 2011 Jun 22;100(12):2875-82. doi: 10.1016/j.bpj.2011.05.014.


The challenges of integrating molecular imaging into the optimization of cancer therapy.

Patel GS, Kiuchi T, Lawler K, Ofo E, Fruhwirth GO, Kelleher M, Shamil E, Zhang R, Selvin PR, Santis G, Spicer J, Woodman N, Gillett CE, Barber PR, Vojnovic B, Kéri G, Schaeffter T, Goh V, O'Doherty MJ, Ellis PA, Ng T.

Integr Biol (Camb). 2011 Jun;3(6):603-31. doi: 10.1039/c0ib00131g. Epub 2011 May 4. Review.


Improved hidden Markov models for molecular motors, part 2: extensions and application to experimental data.

Syed S, Müllner FE, Selvin PR, Sigworth FJ.

Biophys J. 2010 Dec 1;99(11):3696-703. doi: 10.1016/j.bpj.2010.09.066.


Improved hidden Markov models for molecular motors, part 1: basic theory.

Müllner FE, Syed S, Selvin PR, Sigworth FJ.

Biophys J. 2010 Dec 1;99(11):3684-95. doi: 10.1016/j.bpj.2010.09.067.


Counting bungarotoxin binding sites of nicotinic acetylcholine receptors in mammalian cells with high signal/noise ratios.

Simonson PD, Deberg HA, Ge P, Alexander JK, Jeyifous O, Green WN, Selvin PR.

Biophys J. 2010 Nov 17;99(10):L81-3. doi: 10.1016/j.bpj.2010.08.076.


Formation of salt bridges mediates internal dimerization of myosin VI medial tail domain.

Kim H, Hsin J, Liu Y, Selvin PR, Schulten K.

Structure. 2010 Nov 10;18(11):1443-9. doi: 10.1016/j.str.2010.09.011.


Super-accuracy and super-resolution getting around the diffraction limit.

Toprak E, Kural C, Selvin PR.

Methods Enzymol. 2010;475:1-26. doi: 10.1016/S0076-6879(10)75001-1.


Myosin VI undergoes a 180 degrees power stroke implying an uncoupling of the front lever arm.

Reifenberger JG, Toprak E, Kim H, Safer D, Sweeney HL, Selvin PR.

Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18255-60. doi: 10.1073/pnas.0900005106. Epub 2009 Oct 14.


Myosin VI dimerization triggers an unfolding of a three-helix bundle in order to extend its reach.

Mukherjea M, Llinas P, Kim H, Travaglia M, Safer D, Ménétrey J, Franzini-Armstrong C, Selvin PR, Houdusse A, Sweeney HL.

Mol Cell. 2009 Aug 14;35(3):305-15. doi: 10.1016/j.molcel.2009.07.010. Epub 2009 Aug 6.


Why kinesin is so processive.

Toprak E, Yildiz A, Hoffman MT, Rosenfeld SS, Selvin PR.

Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12717-22. doi: 10.1073/pnas.0808396106. Epub 2009 Jul 15.


FIONA on Caenorhabditis elegans.

Kural C, Nonet ML, Selvin PR.

Biochemistry. 2009 Jun 9;48(22):4663-5. doi: 10.1021/bi8023477.


The role of microtubule movement in bidirectional organelle transport.

Kulic IM, Brown AE, Kim H, Kural C, Blehm B, Selvin PR, Nelson PC, Gelfand VI.

Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10011-6. doi: 10.1073/pnas.0800031105. Epub 2008 Jul 14.


Extent of voltage sensor movement during gating of shaker K+ channels.

Posson DJ, Selvin PR.

Neuron. 2008 Jul 10;59(1):98-109. doi: 10.1016/j.neuron.2008.05.006.


New 9- or 10-dentate luminescent lanthanide chelates.

Ge P, Selvin PR.

Bioconjug Chem. 2008 May;19(5):1105-11. doi: 10.1021/bc800030z. Epub 2008 Apr 29.


The mitotic kinesin CENP-E is a processive transport motor.

Yardimci H, van Duffelen M, Mao Y, Rosenfeld SS, Selvin PR.

Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6016-21. doi: 10.1073/pnas.0711314105. Epub 2008 Apr 21.


Single-molecule fluorescence to study molecular motors.

Park H, Toprak E, Selvin PR.

Q Rev Biophys. 2007 Feb;40(1):87-111. Epub 2007 Jul 31. Review.


Three-dimensional particle tracking via bifocal imaging.

Toprak E, Balci H, Blehm BH, Selvin PR.

Nano Lett. 2007 Jul;7(7):2043-5. Epub 2007 Jun 21. Review.


How myosin VI coordinates its heads during processive movement.

Sweeney HL, Park H, Zong AB, Yang Z, Selvin PR, Rosenfeld SS.

EMBO J. 2007 Jun 6;26(11):2682-92. Epub 2007 May 17.


Determination of haplotypes from single DNA molecules: a method for single-molecule barcoding.

Xiao M, Gordon MP, Phong A, Ha C, Chan TF, Cai D, Selvin PR, Kwok PY.

Hum Mutat. 2007 Sep;28(9):913-21.


Tracking melanosomes inside a cell to study molecular motors and their interaction.

Kural C, Serpinskaya AS, Chou YH, Goldman RD, Gelfand VI, Selvin PR.

Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5378-82. Epub 2007 Mar 16.


Microtubule binding by dynactin is required for microtubule organization but not cargo transport.

Kim H, Ling SC, Rogers GC, Kural C, Selvin PR, Rogers SL, Gelfand VI.

J Cell Biol. 2007 Feb 26;176(5):641-51.


New fluorescent tools for watching nanometer-scale conformational changes of single molecules.

Toprak E, Selvin PR.

Annu Rev Biophys Biomol Struct. 2007;36:349-69. Review.


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