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Items: 1 to 50 of 121

1.

Incomplete penetrance for isolated congenital asplenia in humans with mutations in translated and untranslated RPSA exons.

Bolze A, Boisson B, Bosch B, Antipenko A, Bouaziz M, Sackstein P, Chaker-Margot M, Barlogis V, Briggs T, Colino E, Elmore AC, Fischer A, Genel F, Hewlett A, Jedidi M, Kelecic J, Krüger R, Ku CL, Kumararatne D, Lefevre-Utile A, Loughlin S, Mahlaoui N, Markus S, Garcia JM, Nizon M, Oleastro M, Pac M, Picard C, Pollard AJ, Rodriguez-Gallego C, Thomas C, Von Bernuth H, Worth A, Meyts I, Risolino M, Selleri L, Puel A, Klinge S, Abel L, Casanova JL.

Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8007-E8016. doi: 10.1073/pnas.1805437115. Epub 2018 Aug 2.

PMID:
30072435
2.

Pbx loss in cranial neural crest, unlike in epithelium, results in cleft palate only and a broader midface.

Welsh IC, Hart J, Brown JM, Hansen K, Rocha Marques M, Aho RJ, Grishina I, Hurtado R, Herzlinger D, Ferretti E, Garcia-Garcia MJ, Selleri L.

J Anat. 2018 Aug;233(2):222-242. doi: 10.1111/joa.12821. Epub 2018 May 23.

3.

Face morphogenesis is promoted by Pbx-dependent EMT via regulation of Snail1 during frontonasal prominence fusion.

Losa M, Risolino M, Li B, Hart J, Quintana L, Grishina I, Yang H, Choi IF, Lewicki P, Khan S, Aho R, Feenstra J, Vincent CT, Brown AMC, Ferretti E, Williams T, Selleri L.

Development. 2018 Mar 1;145(5). pii: dev157628. doi: 10.1242/dev.157628.

4.

PBX transcription factors drive pulmonary vascular adaptation to birth.

McCulley DJ, Wienhold MD, Hines EA, Hacker TA, Rogers A, Pewowaruk RJ, Zewdu R, Chesler NC, Selleri L, Sun X.

J Clin Invest. 2018 Feb 1;128(2):655-667. doi: 10.1172/JCI93395. Epub 2017 Dec 18.

5.

De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.

Slavotinek A, Risolino M, Losa M, Cho MT, Monaghan KG, Schneidman-Duhovny D, Parisotto S, Herkert JC, Stegmann APA, Miller K, Shur N, Chui J, Muller E, DeBrosse S, Szot JO, Chapman G, Pachter NS, Winlaw DS, Mendelsohn BA, Dalton J, Sarafoglou K, Karachunski PI, Lewis JM, Pedro H, Dunwoodie SL, Selleri L, Shieh J.

Hum Mol Genet. 2017 Dec 15;26(24):4849-4860. doi: 10.1093/hmg/ddx363.

PMID:
29036646
6.

Toward Microsurgical Correction of Cleft Lip Ex Utero through Restoration of Craniofacial Developmental Programs.

Dong X, Landford WN, Hart J, Risolino M, Kaymakcalan O, Jin J, Toyoda Y, Ferretti E, Selleri L, Spector JA.

Plast Reconstr Surg. 2017 Jul;140(1):75-85. doi: 10.1097/PRS.0000000000003417.

7.

A Hox-Embedded Long Noncoding RNA: Is It All Hot Air?

Selleri L, Bartolomei MS, Bickmore WA, He L, Stubbs L, Reik W, Barsh GS.

PLoS Genet. 2016 Dec 15;12(12):e1006485. doi: 10.1371/journal.pgen.1006485. eCollection 2016 Dec. No abstract available.

8.

Ovarian Cancer Chemoresistance Relies on the Stem Cell Reprogramming Factor PBX1.

Jung JG, Shih IM, Park JT, Gerry E, Kim TH, Ayhan A, Handschuh K, Davidson B, Fader AN, Selleri L, Wang TL.

Cancer Res. 2016 Nov 1;76(21):6351-6361. Epub 2016 Sep 2.

9.

Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns.

Hanley O, Zewdu R, Cohen LJ, Jung H, Lacombe J, Philippidou P, Lee DH, Selleri L, Dasen JS.

Neuron. 2016 Sep 7;91(5):1005-1020. doi: 10.1016/j.neuron.2016.07.043. Epub 2016 Aug 25.

10.

A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease.

Villaescusa JC, Li B, Toledo EM, Rivetti di Val Cervo P, Yang S, Stott SR, Kaiser K, Islam S, Gyllborg D, Laguna-Goya R, Landreh M, Lönnerberg P, Falk A, Bergman T, Barker RA, Linnarsson S, Selleri L, Arenas E.

EMBO J. 2016 Sep 15;35(18):1963-78. doi: 10.15252/embj.201593725. Epub 2016 Jun 28.

11.

The FaceBase Consortium: a comprehensive resource for craniofacial researchers.

Brinkley JF, Fisher S, Harris MP, Holmes G, Hooper JE, Jabs EW, Jones KL, Kesselman C, Klein OD, Maas RL, Marazita ML, Selleri L, Spritz RA, van Bakel H, Visel A, Williams TJ, Wysocka J; FaceBase Consortium, Chai Y.

Development. 2016 Jul 15;143(14):2677-88. doi: 10.1242/dev.135434. Epub 2016 Jun 10.

12.

Pbx1 is required for adult subventricular zone neurogenesis.

Grebbin BM, Hau AC, Groß A, Anders-Maurer M, Schramm J, Koss M, Wille C, Mittelbronn M, Selleri L, Schulte D.

Development. 2016 Jul 1;143(13):2281-91. doi: 10.1242/dev.128033. Epub 2016 May 25.

13.

Spleen hypoplasia leads to abnormal stress hematopoiesis in mice with loss of Pbx homeoproteins in splenic mesenchyme.

Zewdu R, Risolino M, Barbulescu A, Ramalingam P, Butler JM, Selleri L.

J Anat. 2016 Jul;229(1):153-69. doi: 10.1111/joa.12479. Epub 2016 Apr 14.

14.

Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons.

Golonzhka O, Nord A, Tang PLF, Lindtner S, Ypsilanti AR, Ferretti E, Visel A, Selleri L, Rubenstein JLR.

Neuron. 2015 Dec 16;88(6):1192-1207. doi: 10.1016/j.neuron.2015.10.045. Epub 2015 Dec 6.

15.

Enhancer divergence and cis-regulatory evolution in the human and chimp neural crest.

Prescott SL, Srinivasan R, Marchetto MC, Grishina I, Narvaiza I, Selleri L, Gage FH, Swigut T, Wysocka J.

Cell. 2015 Sep 24;163(1):68-83. doi: 10.1016/j.cell.2015.08.036. Epub 2015 Sep 10.

16.

Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning.

Hurtado R, Zewdu R, Mtui J, Liang C, Aho R, Kurylo C, Selleri L, Herzlinger D.

Development. 2015 Aug 1;142(15):2653-64. doi: 10.1242/dev.124776. Epub 2015 Jul 2.

17.

An allelic series of miR-17 ∼ 92-mutant mice uncovers functional specialization and cooperation among members of a microRNA polycistron.

Han YC, Vidigal JA, Mu P, Yao E, Singh I, González AJ, Concepcion CP, Bonetti C, Ogrodowski P, Carver B, Selleri L, Betel D, Leslie C, Ventura A.

Nat Genet. 2015 Jul;47(7):766-75. doi: 10.1038/ng.3321. Epub 2015 Jun 1.

18.

Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution.

Vierstra J, Rynes E, Sandstrom R, Zhang M, Canfield T, Hansen RS, Stehling-Sun S, Sabo PJ, Byron R, Humbert R, Thurman RE, Johnson AK, Vong S, Lee K, Bates D, Neri F, Diegel M, Giste E, Haugen E, Dunn D, Wilken MS, Josefowicz S, Samstein R, Chang KH, Eichler EE, De Bruijn M, Reh TA, Skoultchi A, Rudensky A, Orkin SH, Papayannopoulou T, Treuting PM, Selleri L, Kaul R, Groudine M, Bender MA, Stamatoyannopoulos JA.

Science. 2014 Nov 21;346(6212):1007-12. doi: 10.1126/science.1246426.

19.

A comparative encyclopedia of DNA elements in the mouse genome.

Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, Sandstrom R, Ma Z, Davis C, Pope BD, Shen Y, Pervouchine DD, Djebali S, Thurman RE, Kaul R, Rynes E, Kirilusha A, Marinov GK, Williams BA, Trout D, Amrhein H, Fisher-Aylor K, Antoshechkin I, DeSalvo G, See LH, Fastuca M, Drenkow J, Zaleski C, Dobin A, Prieto P, Lagarde J, Bussotti G, Tanzer A, Denas O, Li K, Bender MA, Zhang M, Byron R, Groudine MT, McCleary D, Pham L, Ye Z, Kuan S, Edsall L, Wu YC, Rasmussen MD, Bansal MS, Kellis M, Keller CA, Morrissey CS, Mishra T, Jain D, Dogan N, Harris RS, Cayting P, Kawli T, Boyle AP, Euskirchen G, Kundaje A, Lin S, Lin Y, Jansen C, Malladi VS, Cline MS, Erickson DT, Kirkup VM, Learned K, Sloan CA, Rosenbloom KR, Lacerda de Sousa B, Beal K, Pignatelli M, Flicek P, Lian J, Kahveci T, Lee D, Kent WJ, Ramalho Santos M, Herrero J, Notredame C, Johnson A, Vong S, Lee K, Bates D, Neri F, Diegel M, Canfield T, Sabo PJ, Wilken MS, Reh TA, Giste E, Shafer A, Kutyavin T, Haugen E, Dunn D, Reynolds AP, Neph S, Humbert R, Hansen RS, De Bruijn M, Selleri L, Rudensky A, Josefowicz S, Samstein R, Eichler EE, Orkin SH, Levasseur D, Papayannopoulou T, Chang KH, Skoultchi A, Gosh S, Disteche C, Treuting P, Wang Y, Weiss MJ, Blobel GA, Cao X, Zhong S, Wang T, Good PJ, Lowdon RF, Adams LB, Zhou XQ, Pazin MJ, Feingold EA, Wold B, Taylor J, Mortazavi A, Weissman SM, Stamatoyannopoulos JA, Snyder MP, Guigo R, Gingeras TR, Gilbert DM, Hardison RC, Beer MA, Ren B; Mouse ENCODE Consortium.

Nature. 2014 Nov 20;515(7527):355-64. doi: 10.1038/nature13992.

20.

ESCRT-II/Vps25 constrains digit number by endosome-mediated selective modulation of FGF-SHH signaling.

Handschuh K, Feenstra J, Koss M, Ferretti E, Risolino M, Zewdu R, Sahai MA, Bénazet JD, Peng XP, Depew MJ, Quintana L, Sharpe J, Wang B, Alcorn H, Rivi R, Butcher S, Manak JR, Vaccari T, Weinstein H, Anderson KV, Lacy E, Selleri L.

Cell Rep. 2014 Oct 23;9(2):674-87. doi: 10.1016/j.celrep.2014.09.019. Epub 2014 Oct 16.

21.

Pbx1 activates Fgf10 in the mesenchyme of developing lungs.

Li W, Lin CY, Shang C, Han P, Xiong Y, Lin CJ, Yang J, Selleri L, Chang CP.

Genesis. 2014 May;52(5):399-407. doi: 10.1002/dvg.22764. Epub 2014 Mar 14.

22.

ADAM17 controls endochondral ossification by regulating terminal differentiation of chondrocytes.

Hall KC, Hill D, Otero M, Plumb DA, Froemel D, Dragomir CL, Maretzky T, Boskey A, Crawford HC, Selleri L, Goldring MB, Blobel CP.

Mol Cell Biol. 2013 Aug;33(16):3077-90. doi: 10.1128/MCB.00291-13. Epub 2013 Jun 3.

23.

Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia.

Bolze A, Mahlaoui N, Byun M, Turner B, Trede N, Ellis SR, Abhyankar A, Itan Y, Patin E, Brebner S, Sackstein P, Puel A, Picard C, Abel L, Quintana-Murci L, Faust SN, Williams AP, Baretto R, Duddridge M, Kini U, Pollard AJ, Gaud C, Frange P, Orbach D, Emile JF, Stephan JL, Sorensen R, Plebani A, Hammarstrom L, Conley ME, Selleri L, Casanova JL.

Science. 2013 May 24;340(6135):976-8. doi: 10.1126/science.1234864. Epub 2013 Apr 11.

24.

The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo.

Feldhahn N, Ferretti E, Robbiani DF, Callen E, Deroubaix S, Selleri L, Nussenzweig A, Nussenzweig MC.

EMBO J. 2012 Oct 17;31(20):4045-56. doi: 10.1038/emboj.2012.247. Epub 2012 Aug 31.

25.

Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.

Koss M, Bolze A, Brendolan A, Saggese M, Capellini TD, Bojilova E, Boisson B, Prall OW, Elliott DA, Solloway M, Lenti E, Hidaka C, Chang CP, Mahlaoui N, Harvey RP, Casanova JL, Selleri L.

Dev Cell. 2012 May 15;22(5):913-26. doi: 10.1016/j.devcel.2012.02.009. Epub 2012 May 3.

26.

A conserved Pbx-Wnt-p63-Irf6 regulatory module controls face morphogenesis by promoting epithelial apoptosis.

Ferretti E, Li B, Zewdu R, Wells V, Hebert JM, Karner C, Anderson MJ, Williams T, Dixon J, Dixon MJ, Depew MJ, Selleri L.

Dev Cell. 2011 Oct 18;21(4):627-41. doi: 10.1016/j.devcel.2011.08.005. Epub 2011 Oct 6.

27.

Epigenetic regulation of early osteogenesis and mineralized tissue formation by a HOXA10-PBX1-associated complex.

Gordon JA, Hassan MQ, Koss M, Montecino M, Selleri L, van Wijnen AJ, Stein JL, Stein GS, Lian JB.

Cells Tissues Organs. 2011;194(2-4):146-50. doi: 10.1159/000324790. Epub 2011 May 19.

28.

Hox and Pbx factors control retinoic acid synthesis during hindbrain segmentation.

Vitobello A, Ferretti E, Lampe X, Vilain N, Ducret S, Ori M, Spetz JF, Selleri L, Rijli FM.

Dev Cell. 2011 Apr 19;20(4):469-82. doi: 10.1016/j.devcel.2011.03.011.

29.

Control of pelvic girdle development by genes of the Pbx family and Emx2.

Capellini TD, Handschuh K, Quintana L, Ferretti E, Di Giacomo G, Fantini S, Vaccari G, Clarke SL, Wenger AM, Bejerano G, Sharpe J, Zappavigna V, Selleri L.

Dev Dyn. 2011 May;240(5):1173-89. doi: 10.1002/dvdy.22617. Epub 2011 Mar 31.

30.

Pbx homeodomain proteins: TALEnted regulators of limb patterning and outgrowth.

Capellini TD, Zappavigna V, Selleri L.

Dev Dyn. 2011 May;240(5):1063-86. doi: 10.1002/dvdy.22605. Epub 2011 Mar 17. Review.

31.

Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1.

Capellini TD, Vaccari G, Ferretti E, Fantini S, He M, Pellegrini M, Quintana L, Di Giacomo G, Sharpe J, Selleri L, Zappavigna V.

Development. 2010 Aug 1;137(15):2559-69. doi: 10.1242/dev.048819.

32.

Ectopic Meis1 expression in the mouse limb bud alters P-D patterning in a Pbx1-independent manner.

Mercader N, Selleri L, Criado LM, Pallares P, Parras C, Cleary ML, Torres M.

Int J Dev Biol. 2009;53(8-10):1483-94. doi: 10.1387/ijdb.072430nm.

33.

Conservation of notochord gene expression across chordates: insights from the Leprecan gene family.

Capellini TD, Dunn MP, Passamaneck YJ, Selleri L, Di Gregorio A.

Genesis. 2008 Nov;46(11):683-96. doi: 10.1002/dvg.20406.

34.

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.

Stankunas K, Shang C, Twu KY, Kao SC, Jenkins NA, Copeland NG, Sanyal M, Selleri L, Cleary ML, Chang CP.

Circ Res. 2008 Sep 26;103(7):702-9. doi: 10.1161/CIRCRESAHA.108.175489. Epub 2008 Aug 21.

35.

Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome.

Capellini TD, Zewdu R, Di Giacomo G, Asciutti S, Kugler JE, Di Gregorio A, Selleri L.

Dev Biol. 2008 Sep 15;321(2):500-14. doi: 10.1016/j.ydbio.2008.04.005. Epub 2008 Apr 16.

36.

Interleukin-10 expression in macrophages during phagocytosis of apoptotic cells is mediated by homeodomain proteins Pbx1 and Prep-1.

Chung EY, Liu J, Homma Y, Zhang Y, Brendolan A, Saggese M, Han J, Silverstein R, Selleri L, Ma X.

Immunity. 2007 Dec;27(6):952-64.

37.

Compartmentalisation of T cells expressing CD8alpha and TCRbeta in developing thymus of sea bass Dicentrarchus labrax (L.).

Picchietti S, Guerra L, Selleri L, Buonocore F, Abelli L, Scapigliati G, Mazzini M, Fausto AM.

Dev Comp Immunol. 2008;32(2):92-9. Epub 2007 May 21.

PMID:
17532466
38.

Cooperation between p27 and p107 during endochondral ossification suggests a genetic pathway controlled by p27 and p130.

Yeh N, Miller JP, Gaur T, Capellini TD, Nikolich-Zugich J, de la Hoz C, Selleri L, Bromage TG, van Wijnen AJ, Stein GS, Lian JB, Vidal A, Koff A.

Mol Cell Biol. 2007 Jul;27(14):5161-71. Epub 2007 May 14.

39.

B-cell development fails in the absence of the Pbx1 proto-oncogene.

Sanyal M, Tung JW, Karsunky H, Zeng H, Selleri L, Weissman IL, Herzenberg LA, Cleary ML.

Blood. 2007 May 15;109(10):4191-9. Epub 2007 Jan 23.

40.

Development and function of the mammalian spleen.

Brendolan A, Rosado MM, Carsetti R, Selleri L, Dear TN.

Bioessays. 2007 Feb;29(2):166-77. Review.

PMID:
17226804
41.

Pax6 is regulated by Meis and Pbx homeoproteins during pancreatic development.

Zhang X, Rowan S, Yue Y, Heaney S, Pan Y, Brendolan A, Selleri L, Maas RL.

Dev Biol. 2006 Dec 15;300(2):748-57. Epub 2006 Jun 27.

42.

Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype.

Ferretti E, Villaescusa JC, Di Rosa P, Fernandez-Diaz LC, Longobardi E, Mazzieri R, Miccio A, Micali N, Selleri L, Ferrari G, Blasi F.

Mol Cell Biol. 2006 Aug;26(15):5650-62.

43.

Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression.

Capellini TD, Di Giacomo G, Salsi V, Brendolan A, Ferretti E, Srivastava D, Zappavigna V, Selleri L.

Development. 2006 Jun;133(11):2263-73. Epub 2006 May 3.

44.

Hox cofactors in vertebrate development.

Moens CB, Selleri L.

Dev Biol. 2006 Mar 15;291(2):193-206. Epub 2006 Mar 3. Review.

45.

Spatio-temporal expression of Pbx3 during mouse organogenesis.

Di Giacomo G, Koss M, Capellini TD, Brendolan A, Pöpperl H, Selleri L.

Gene Expr Patterns. 2006 Oct;6(7):747-57. Epub 2006 Jan 24.

PMID:
16434237
46.

A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny.

Brendolan A, Ferretti E, Salsi V, Moses K, Quaggin S, Blasi F, Cleary ML, Selleri L.

Development. 2005 Jul;132(13):3113-26. Erratum in: Development. 2005 Aug;132(15):3575.

47.

Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs.

Manley NR, Selleri L, Brendolan A, Gordon J, Cleary ML.

Dev Biol. 2004 Dec 15;276(2):301-12.

48.

Pbx3 deficiency results in central hypoventilation.

Rhee JW, Arata A, Selleri L, Jacobs Y, Arata S, Onimaru H, Cleary ML.

Am J Pathol. 2004 Oct;165(4):1343-50.

49.

The TALE homeodomain protein Pbx2 is not essential for development and long-term survival.

Selleri L, DiMartino J, van Deursen J, Brendolan A, Sanyal M, Boon E, Capellini T, Smith KS, Rhee J, Pöpperl H, Grosveld G, Cleary ML.

Mol Cell Biol. 2004 Jun;24(12):5324-31.

50.

Pbx1 is essential for adrenal development and urogenital differentiation.

Schnabel CA, Selleri L, Cleary ML.

Genesis. 2003 Nov;37(3):123-30.

PMID:
14595835

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