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Aurora A kinase inhibition destabilizes PAX3-FOXO1 and MYCN and synergizes with Navitoclax to induce Rhabdomyosarcoma cell death.

Ommer J, Selfe JL, Wachtel M, O'Brien EM, Laubscher D, Roemmele M, Kasper S, Delattre O, Surdez D, Petts G, Kelsey A, Shipley J, Schäfer BW.

Cancer Res. 2019 Dec 30. pii: canres.1479.2019. doi: 10.1158/0008-5472.CAN-19-1479. [Epub ahead of print]


Red flags for the early detection of spinal infection in back pain patients.

Yusuf M, Finucane L, Selfe J.

BMC Musculoskelet Disord. 2019 Dec 13;20(1):606. doi: 10.1186/s12891-019-2949-6.


Targeted Treatment Protocol in Patellofemoral Pain: Does Treatment Designed According to Subgroups Improve Clinical Outcomes in Patients Unresponsive to Multimodal Treatment?

Yosmaoğlu HB, Selfe J, Sonmezer E, Sahin İE, Duygu SÇ, Acar Ozkoslu M, Richards J, Janssen J.

Sports Health. 2019 Nov 21:1941738119883272. doi: 10.1177/1941738119883272. [Epub ahead of print]


Excitatory GABAergic signalling is associated with benzodiazepine resistance in status epilepticus.

Burman RJ, Selfe JS, Lee JH, van den Berg M, Calin A, Codadu NK, Wright R, Newey SE, Parrish RR, Katz AA, Wilmshurst JM, Akerman CJ, Trevelyan AJ, Raimondo JV.

Brain. 2019 Nov 1;142(11):3482-3501. doi: 10.1093/brain/awz283.


Toward the Development of Data-Driven Diagnostic Subgroups for People With Patellofemoral Pain Using Modifiable Clinical, Biomechanical, and Imaging Features.

Drew BT, Conaghan PG, Smith TO, Selfe J, Hensor EMA, Dube B, Grainger AJ, Redmond AC.

J Orthop Sports Phys Ther. 2019 Jul;49(7):536-547. doi: 10.2519/jospt.2019.8607. Epub 2019 Jun 18.


IGF signalling in germ cells and testicular germ cell tumours: roles and therapeutic approaches.

Selfe J, Shipley JM.

Andrology. 2019 Jul;7(4):536-544. doi: 10.1111/andr.12658. Epub 2019 Jun 9. Review.


A loaded self-managed exercise programme for patellofemoral pain: a mixed methods feasibility study.

Smith BE, Hendrick P, Bateman M, Moffatt F, Rathleff MS, Selfe J, Smith TO, Logan P.

BMC Musculoskelet Disord. 2019 Mar 27;20(1):129. doi: 10.1186/s12891-019-2516-1.


Knee problems are common in young adults and associated with physical activity and not obesity: the findings of a cross-sectional survey in a university cohort.

Ibeachu C, Selfe J, Sutton CJ, Dey P.

BMC Musculoskelet Disord. 2019 Mar 18;20(1):116. doi: 10.1186/s12891-019-2487-2.


Influence and benefits of foot orthoses on kinematics, kinetics and muscle activation during step descent task.

Bonifácio D, Richards J, Selfe J, Curran S, Trede R.

Gait Posture. 2018 Sep;65:106-111. doi: 10.1016/j.gaitpost.2018.07.041. Epub 2018 Jul 24.


Author Correction: Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness.

Holme H, Gulati A, Brough R, Fleuren EDG, Bajrami I, Campbell J, Chong IY, Costa-Cabral S, Elliott R, Fenton T, Frankum J, Jones SE, Menon M, Miller R, Pemberton HN, Postel-Vinay S, Rafiq R, Selfe JL, von Kriegsheim A, Munoz AG, Rodriguez J, Shipley J, van der Graaf WTA, Williamson CT, Ryan CJ, Pettitt S, Ashworth A, Strauss SJ, Lord CJ.

Sci Rep. 2018 Aug 21;8(1):12771. doi: 10.1038/s41598-018-30922-8.


Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness.

Holme H, Gulati A, Brough R, Fleuren EDG, Bajrami I, Campbell J, Chong IY, Costa-Cabral S, Elliott R, Fenton T, Frankum J, Jones SE, Menon M, Miller R, Pemberton HN, Postel-Vinay S, Rafiq R, Selfe JL, von Kriegsheim A, Munoz AG, Rodriguez J, Shipley J, van der Graaf WTA, Williamson CT, Ryan CJ, Pettitt S, Ashworth A, Strauss SJ, Lord CJ.

Sci Rep. 2018 Jul 13;8(1):10614. doi: 10.1038/s41598-018-29043-z. Erratum in: Sci Rep. 2018 Aug 21;8(1):12771.


Assessment and management of cauda equina syndrome.

Greenhalgh S, Finucane L, Mercer C, Selfe J.

Musculoskelet Sci Pract. 2018 Oct;37:69-74. doi: 10.1016/j.msksp.2018.06.002. Epub 2018 Jun 7.


The effects of three quarter and full length foot orthoses on knee mechanics in healthy subjects and patellofemoral pain patients when walking and descending stairs.

Burston J, Richards J, Selfe J.

Gait Posture. 2018 May;62:518-522. doi: 10.1016/j.gaitpost.2018.04.018. Epub 2018 Apr 17.


Delayed effects of a 20-min crushed ice application on knee joint position sense assessed by a functional task during a re-warming period.

Alexander J, Richards J, Attah O, Cheema S, Snook J, Wisdell C, May K, Selfe J.

Gait Posture. 2018 May;62:173-178. doi: 10.1016/j.gaitpost.2018.03.015. Epub 2018 Mar 6.


The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells.

O'Brien EM, Selfe JL, Martins AS, Walters ZS, Shipley JM.

BMC Cancer. 2018 Feb 21;18(1):217. doi: 10.1186/s12885-018-4129-8.


A service evaluation and improvement project: a three year systematic audit cycle of the physiotherapy treatment for Lateral Epicondylalgia.

Barratt PA, Selfe J.

Physiotherapy. 2018 Jun;104(2):209-216. doi: 10.1016/ Epub 2017 Sep 22.


The experience of living with patellofemoral pain-loss, confusion and fear-avoidance: a UK qualitative study.

Smith BE, Moffatt F, Hendrick P, Bateman M, Rathleff MS, Selfe J, Smith TO, Logan P.

BMJ Open. 2018 Jan 23;8(1):e018624. doi: 10.1136/bmjopen-2017-018624.


Incidence and prevalence of patellofemoral pain: A systematic review and meta-analysis.

Smith BE, Selfe J, Thacker D, Hendrick P, Bateman M, Moffatt F, Rathleff MS, Smith TO, Logan P.

PLoS One. 2018 Jan 11;13(1):e0190892. doi: 10.1371/journal.pone.0190892. eCollection 2018. Review.


IGF1R signalling in testicular germ cell tumour cells impacts on cell survival and acquired cisplatin resistance.

Selfe J, Goddard NC, McIntyre A, Taylor KR, Renshaw J, Popov SD, Thway K, Summersgill B, Huddart RA, Gilbert DC, Shipley JM.

J Pathol. 2018 Feb;244(2):242-253. doi: 10.1002/path.5008. Epub 2018 Jan 10.


Can physical assessment techniques aid diagnosis in people with chronic fatigue syndrome/myalgic encephalomyelitis? A diagnostic accuracy study.

Hives L, Bradley A, Richards J, Sutton C, Selfe J, Basu B, Maguire K, Sumner G, Gaber T, Mukherjee A, Perrin RN.

BMJ Open. 2017 Nov 13;7(11):e017521. doi: 10.1136/bmjopen-2017-017521.


ATR Is a Therapeutic Target in Synovial Sarcoma.

Jones SE, Fleuren EDG, Frankum J, Konde A, Williamson CT, Krastev DB, Pemberton HN, Campbell J, Gulati A, Elliott R, Menon M, Selfe JL, Brough R, Pettitt SJ, Niedzwiedz W, van der Graaf WTA, Shipley J, Ashworth A, Lord CJ.

Cancer Res. 2017 Dec 15;77(24):7014-7026. doi: 10.1158/0008-5472.CAN-17-2056. Epub 2017 Oct 16.


Thermographic imaging in sports and exercise medicine: A Delphi study and consensus statement on the measurement of human skin temperature.

Moreira DG, Costello JT, Brito CJ, Adamczyk JG, Ammer K, Bach AJE, Costa CMA, Eglin C, Fernandes AA, Fernández-Cuevas I, Ferreira JJA, Formenti D, Fournet D, Havenith G, Howell K, Jung A, Kenny GP, Kolosovas-Machuca ES, Maley MJ, Merla A, Pascoe DD, Priego Quesada JI, Schwartz RG, Seixas ARD, Selfe J, Vainer BG, Sillero-Quintana M.

J Therm Biol. 2017 Oct;69:155-162. doi: 10.1016/j.jtherbio.2017.07.006. Epub 2017 Jul 18. Review.


The effectiveness of ultrasound guided hydrodistension and physiotherapy in the treatment of frozen shoulder/adhesive capsulitis in primary care: a single centre service evaluation.

Bryant M, Gough A, Selfe J, Richards J, Burgess E.

Shoulder Elbow. 2017 Oct;9(4):292-298. doi: 10.1177/1758573217701063. Epub 2017 May 17.


Is keep/refer decision making an integral part of national guidelines for the physiotherapy profession within Europe? A review.

Lackenbauer W, Janssen J, Roddam H, Selfe J.

Physiotherapy. 2017 Dec;103(4):352-360. doi: 10.1016/ Epub 2016 Nov 28. Review.


The effect of targeted treatment on people with patellofemoral pain: a pragmatic, randomised controlled feasibility study.

Drew BT, Conaghan PG, Smith TO, Selfe J, Redmond AC.

BMC Musculoskelet Disord. 2017 Aug 4;18(1):338. doi: 10.1186/s12891-017-1698-7.


Study protocol: a mixed methods feasibility study for a loaded self-managed exercise programme for patellofemoral pain.

Smith BE, Hendrick P, Bateman M, Moffatt F, Rathleff MS, Selfe J, Smith TO, Logan P.

Pilot Feasibility Stud. 2017 Jul 20;4:24. doi: 10.1186/s40814-017-0167-2. eCollection 2018. Erratum in: Pilot Feasibility Stud. 2017 Oct 24;3:48.


Should exercises be painful in the management of chronic musculoskeletal pain? A systematic review and meta-analysis.

Smith BE, Hendrick P, Smith TO, Bateman M, Moffatt F, Rathleff MS, Selfe J, Logan P.

Br J Sports Med. 2017 Dec;51(23):1679-1687. doi: 10.1136/bjsports-2016-097383. Epub 2017 Jun 8. Review.


Current management strategies for patellofemoral pain: an online survey of 99 practising UK physiotherapists.

Smith BE, Hendrick P, Bateman M, Moffatt F, Rathleff MS, Selfe J, Smith TO, Logan P.

BMC Musculoskelet Disord. 2017 May 8;18(1):181. doi: 10.1186/s12891-017-1539-8.


Fusion gene addiction: can tumours be forced to give up the habit?

Selfe JL, Shipley J.

J Pathol. 2017 Jul;242(3):263-266. doi: 10.1002/path.4902. Epub 2017 May 29.


The effect of different decline angles on the biomechanics of double limb squats and the implications to clinical and training practice.

Richards J, Selfe J, Sinclair J, May K, Thomas G.

J Hum Kinet. 2016 Sep 10;52:125-138. doi: 10.1515/hukin-2015-0200. eCollection 2016 Sep 1.


Effectiveness of early compared with conservative rehabilitation for patients having rotator cuff repair surgery: an overview of systematic reviews.

Mazuquin BF, Wright AC, Russell S, Monga P, Selfe J, Richards J.

Br J Sports Med. 2018 Jan;52(2):111-121. doi: 10.1136/bjsports-2016-095963. Epub 2016 Dec 30. Review.


Impact of fusion gene status versus histology on risk-stratification for rhabdomyosarcoma: Retrospective analyses of patients on UK trials.

Selfe J, Olmos D, Al-Saadi R, Thway K, Chisholm J, Kelsey A, Shipley J.

Pediatr Blood Cancer. 2017 Jul;64(7). doi: 10.1002/pbc.26386. Epub 2016 Dec 30.


MicroRNA and gene co-expression networks characterize biological and clinical behavior of rhabdomyosarcomas.

Missiaglia E, Shepherd CJ, Aladowicz E, Olmos D, Selfe J, Pierron G, Delattre O, Walters Z, Shipley J.

Cancer Lett. 2017 Jan 28;385:251-260. doi: 10.1016/j.canlet.2016.10.011. Epub 2016 Oct 29.


Torque-angle-velocity Relationships and Muscle Performance of Professional and Youth Soccer Players.

Mazuquin BF, Dela Bela LF, Pelegrinelli AR, Dias JM, Carregaro RL, Moura FA, Selfe J, Richards J, Brown LE, Cardoso JR.

Int J Sports Med. 2016 Nov;37(12):992-996. Epub 2016 Aug 1.


Endosialin expression in soft tissue sarcoma as a potential marker of undifferentiated mesenchymal cells.

Thway K, Robertson D, Jones RL, Selfe J, Shipley J, Fisher C, Isacke CM.

Br J Cancer. 2016 Aug 9;115(4):473-9. doi: 10.1038/bjc.2016.214. Epub 2016 Jul 19.


2016 Patellofemoral pain consensus statement from the 4th International Patellofemoral Pain Research Retreat, Manchester. Part 1: Terminology, definitions, clinical examination, natural history, patellofemoral osteoarthritis and patient-reported outcome measures.

Crossley KM, Stefanik JJ, Selfe J, Collins NJ, Davis IS, Powers CM, McConnell J, Vicenzino B, Bazett-Jones DM, Esculier JF, Morrissey D, Callaghan MJ.

Br J Sports Med. 2016 Jul;50(14):839-43. doi: 10.1136/bjsports-2016-096384. Epub 2016 Jun 24. No abstract available.


Influence of a knee brace intervention on perceived pain and patellofemoral loading in recreational athletes.

Sinclair JK, Selfe J, Taylor PJ, Shore HF, Richards JD.

Clin Biomech (Bristol, Avon). 2016 Aug;37:7-12. doi: 10.1016/j.clinbiomech.2016.05.002. Epub 2016 May 8.


The effect of proprioceptive knee bracing on knee stability during three different sport related movement tasks in healthy subjects and the implications to the management of Anterior Cruciate Ligament (ACL) injuries.

Hanzlíková I, Richards J, Tomsa M, Chohan A, May K, Smékal D, Selfe J.

Gait Posture. 2016 Jul;48:165-170. doi: 10.1016/j.gaitpost.2016.05.011. Epub 2016 May 24.


A questionnaire to identify patellofemoral pain in the community: an exploration of measurement properties.

Dey P, Callaghan M, Cook N, Sephton R, Sutton C, Hough E, James J, Saqib R, Selfe J.

BMC Musculoskelet Disord. 2016 May 31;17:237. doi: 10.1186/s12891-016-1097-5.


A Biomechanical Investigation of Selected Lumbopelvic Hip Tests: Implications for the Examination of Walking.

Bailey RW, Richards J, Selfe J.

J Manipulative Physiol Ther. 2016 Jul-Aug;39(6):411-419. doi: 10.1016/j.jmpt.2016.04.007. Epub 2016 May 27.


The Hippo effector TAZ (WWTR1) transforms myoblasts and TAZ abundance is associated with reduced survival in embryonal rhabdomyosarcoma.

Mohamed A, Sun C, De Mello V, Selfe J, Missiaglia E, Shipley J, Murray GI, Zammit PS, Wackerhage H.

J Pathol. 2016 Sep;240(1):3-14. doi: 10.1002/path.4745.


Development of a toolkit for early identification of cauda equina syndrome.

Greenhalgh S, Truman C, Webster V, Selfe J.

Prim Health Care Res Dev. 2016 Nov;17(6):559-567. Epub 2016 Apr 21.


Effect of three cueing devices for people with Parkinson's disease with gait initiation difficulties.

McCandless PJ, Evans BJ, Janssen J, Selfe J, Churchill A, Richards J.

Gait Posture. 2016 Feb;44:7-11. doi: 10.1016/j.gaitpost.2015.11.006. Epub 2015 Nov 12.


The Influence of Minimalist and Maximalist Footwear on Patellofemoral Kinetics During Running.

Sinclair J, Richards J, Selfe J, Fau-Goodwin J, Shore H.

J Appl Biomech. 2016 Aug;32(4):359-64. doi: 10.1123/jab.2015-0249. Epub 2016 Mar 8.


Are there three main subgroups within the patellofemoral pain population? A detailed characterisation study of 127 patients to help develop targeted intervention (TIPPs).

Selfe J, Janssen J, Callaghan M, Witvrouw E, Sutton C, Richards J, Stokes M, Martin D, Dixon J, Hogarth R, Baltzopoulos V, Ritchie E, Arden N, Dey P.

Br J Sports Med. 2016 Jul;50(14):873-80. doi: 10.1136/bjsports-2015-094792. Epub 2016 Feb 1.


An exploratory study into the effects of a 20 minute crushed ice application on knee joint position sense during a small knee bend.

Alexander J, Selfe J, Oliver B, Mee D, Carter A, Scott M, Richards J, May K.

Phys Ther Sport. 2016 Mar;18:21-26. doi: 10.1016/j.ptsp.2015.06.004. Epub 2015 Jun 25.


Sex differences in knee loading in recreational runners.

Sinclair J, Selfe J.

J Biomech. 2015 Jul 16;48(10):2171-5. doi: 10.1016/j.jbiomech.2015.05.016. Epub 2015 May 28.


The Influence of Minimalist Footwear on Knee and Ankle Load during Depth Jumping.

Sinclair J, Hobbs SJ, Selfe J.

Res Sports Med. 2015;23(3):289-301. doi: 10.1080/15438627.2015.1040917. Epub 2015 Jun 8.


Rehabilitation following rotator cuff repair: a systematic review.

Littlewood C, Bateman M, Clark D, Selfe J, Watkinson D, Walton M, Funk L.

Shoulder Elbow. 2015 Apr;7(2):115-24. doi: 10.1177/1758573214567702. Epub 2015 Jan 29. Review.

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