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Items: 1 to 50 of 86

1.

Knockdown of the histone di-methyltransferase G9a in nucleus accumbens shell decreases cocaine self-administration, stress-induced reinstatement, and anxiety.

Anderson EM, Sun H, Guzman D, Taniguchi M, Cowan CW, Maze I, Nestler EJ, Self DW.

Neuropsychopharmacology. 2019 Jul;44(8):1370-1376. doi: 10.1038/s41386-018-0305-4. Epub 2018 Dec 26.

PMID:
30587852
2.

Viral Vector Targeting of Specific Brain Circuits in Neuropsychiatric Disease Models.

Self DW.

Pharmacol Biochem Behav. 2018 Nov;174:1. doi: 10.1016/j.pbb.2018.10.003. No abstract available.

PMID:
30342591
3.

Overexpression of the Histone Dimethyltransferase G9a in Nucleus Accumbens Shell Increases Cocaine Self-Administration, Stress-Induced Reinstatement, and Anxiety.

Anderson EM, Larson EB, Guzman D, Wissman AM, Neve RL, Nestler EJ, Self DW.

J Neurosci. 2018 Jan 24;38(4):803-813. doi: 10.1523/JNEUROSCI.1657-17.2017. Epub 2017 Dec 7.

4.

Inactivation of NMDA Receptors in the Ventral Tegmental Area during Cocaine Self-Administration Prevents GluA1 Upregulation but with Paradoxical Increases in Cocaine-Seeking Behavior.

Guzman D, Carreira MB, Friedman AK, Adachi M, Neve RL, Monteggia LM, Han MH, Cowan CW, Self DW.

J Neurosci. 2018 Jan 17;38(3):575-585. doi: 10.1523/JNEUROSCI.2828-16.2017. Epub 2017 Dec 1.

5.

HDAC5 and Its Target Gene, Npas4, Function in the Nucleus Accumbens to Regulate Cocaine-Conditioned Behaviors.

Taniguchi M, Carreira MB, Cooper YA, Bobadilla AC, Heinsbroek JA, Koike N, Larson EB, Balmuth EA, Hughes BW, Penrod RD, Kumar J, Smith LN, Guzman D, Takahashi JS, Kim TK, Kalivas PW, Self DW, Lin Y, Cowan CW.

Neuron. 2017 Sep 27;96(1):130-144.e6. doi: 10.1016/j.neuron.2017.09.015.

6.

BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors.

Anderson EM, Wissman AM, Chemplanikal J, Buzin N, Guzman D, Larson EB, Neve RL, Nestler EJ, Cowan CW, Self DW.

Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):9469-9474. doi: 10.1073/pnas.1702441114. Epub 2017 Aug 14.

7.

Incubation of cue-induced reinstatement of cocaine, but not sucrose, seeking in C57BL/6J mice.

Nugent AL, Anderson EM, Larson EB, Self DW.

Pharmacol Biochem Behav. 2017 Aug;159:12-17. doi: 10.1016/j.pbb.2017.06.017. Epub 2017 Jun 29.

8.

It's only a matter of time: longevity of cocaine-induced changes in dendritic spine density in the nucleus accumbens.

Anderson EM, Self DW.

Curr Opin Behav Sci. 2017 Feb;13:117-123. doi: 10.1016/j.cobeha.2016.11.013. Epub 2016 Dec 3.

9.

Optogenetic stimulation of accumbens shell or shell projections to lateral hypothalamus produce differential effects on the motivation for cocaine.

Larson EB, Wissman AM, Loriaux AL, Kourrich S, Self DW.

J Neurosci. 2015 Feb 25;35(8):3537-43. doi: 10.1523/JNEUROSCI.1524-14.2015.

10.

Direct regulation of diurnal Drd3 expression and cocaine reward by NPAS2.

Ozburn AR, Falcon E, Twaddle A, Nugent AL, Gillman AG, Spencer SM, Arey RN, Mukherjee S, Lyons-Weiler J, Self DW, McClung CA.

Biol Psychiatry. 2015 Mar 1;77(5):425-433. doi: 10.1016/j.biopsych.2014.07.030. Epub 2014 Aug 13.

11.

Diminished role for dopamine D1 receptors in cocaine addiction?

Self DW.

Biol Psychiatry. 2014 Jul 1;76(1):2-3. doi: 10.1016/j.biopsych.2014.04.006. No abstract available.

12.

ΔFosB induction in striatal medium spiny neuron subtypes in response to chronic pharmacological, emotional, and optogenetic stimuli.

Lobo MK, Zaman S, Damez-Werno DM, Koo JW, Bagot RC, DiNieri JA, Nugent A, Finkel E, Chaudhury D, Chandra R, Riberio E, Rabkin J, Mouzon E, Cachope R, Cheer JF, Han MH, Dietz DM, Self DW, Hurd YL, Vialou V, Nestler EJ.

J Neurosci. 2013 Nov 20;33(47):18381-95. doi: 10.1523/JNEUROSCI.1875-13.2013.

13.

Adenosine A1 and dopamine d1 receptor regulation of AMPA receptor phosphorylation and cocaine-seeking behavior.

Hobson BD, O'Neill CE, Levis SC, Monteggia LM, Neve RL, Self DW, Bachtell RK.

Neuropsychopharmacology. 2013 Sep;38(10):1974-83. doi: 10.1038/npp.2013.96. Epub 2013 Apr 18.

14.

Cocaine self-administration behaviors in ClockΔ19 mice.

Ozburn AR, Larson EB, Self DW, McClung CA.

Psychopharmacology (Berl). 2012 Sep;223(2):169-77. doi: 10.1007/s00213-012-2704-2. Epub 2012 Apr 26.

15.

Overexpression of CREB in the nucleus accumbens shell increases cocaine reinforcement in self-administering rats.

Larson EB, Graham DL, Arzaga RR, Buzin N, Webb J, Green TA, Bass CE, Neve RL, Terwilliger EF, Nestler EJ, Self DW.

J Neurosci. 2011 Nov 9;31(45):16447-57. doi: 10.1523/JNEUROSCI.3070-11.2011.

16.

Striatal signal transduction and drug addiction.

Philibin SD, Hernandez A, Self DW, Bibb JA.

Front Neuroanat. 2011 Sep 20;5:60. doi: 10.3389/fnana.2011.00060. eCollection 2011.

17.

Integrating Behavioral and Molecular Approaches in Mouse: Self-Administration Studies.

Graham DL, Self DW.

In: Kuhn CM, Koob GF, editors. Advances in the Neuroscience of Addiction. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2010. Chapter 5.

18.

Reinforcement-related regulation of AMPA glutamate receptor subunits in the ventral tegmental area enhances motivation for cocaine.

Choi KH, Edwards S, Graham DL, Larson EB, Whisler KN, Simmons D, Friedman AK, Walsh JJ, Rahman Z, Monteggia LM, Eisch AJ, Neve RL, Nestler EJ, Han MH, Self DW.

J Neurosci. 2011 May 25;31(21):7927-37. doi: 10.1523/JNEUROSCI.6014-10.2011.

19.

Emergence of context-associated GluR(1) and ERK phosphorylation in the nucleus accumbens core during withdrawal from cocaine self-administration.

Edwards S, Bachtell RK, Guzman D, Whisler KN, Self DW.

Addict Biol. 2011 Jul;16(3):450-7. doi: 10.1111/j.1369-1600.2010.00296.x. Epub 2011 Feb 11.

20.

Stress-related receptor targets for cocaine addiction.

Self DW.

Biol Psychiatry. 2010 Aug 1;68(3):217-8. doi: 10.1016/j.biopsych.2010.06.006. No abstract available.

PMID:
20643264
21.

Striatal regulation of ΔFosB, FosB, and cFos during cocaine self-administration and withdrawal.

Larson EB, Akkentli F, Edwards S, Graham DL, Simmons DL, Alibhai IN, Nestler EJ, Self DW.

J Neurochem. 2010 Oct;115(1):112-22. doi: 10.1111/j.1471-4159.2010.06907.x. Epub 2010 Aug 3.

22.

Effects of adenosine A2A receptor stimulation on cocaine-seeking behavior in rats.

Bachtell RK, Self DW.

Psychopharmacology (Berl). 2009 Oct;206(3):469-78. doi: 10.1007/s00213-009-1624-2. Epub 2009 Jul 30.

23.

Role of mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior.

Simmons D, Self DW.

Neuropsychopharmacology. 2009 Jul;34(8):1946-57. doi: 10.1038/npp.2009.28. Epub 2009 Mar 11.

24.

Phosphorylation of GluR1, ERK, and CREB during spontaneous withdrawal from chronic heroin self-administration.

Edwards S, Graham DL, Whisler KN, Self DW.

Synapse. 2009 Mar;63(3):224-35. doi: 10.1002/syn.20601.

25.

Renewed cocaine exposure produces transient alterations in nucleus accumbens AMPA receptor-mediated behavior.

Bachtell RK, Self DW.

J Neurosci. 2008 Nov 26;28(48):12808-14. doi: 10.1523/JNEUROSCI.2060-08.2008.

26.

Tropomyosin-related kinase B in the mesolimbic dopamine system: region-specific effects on cocaine reward.

Graham DL, Krishnan V, Larson EB, Graham A, Edwards S, Bachtell RK, Simmons D, Gent LM, Berton O, Bolanos CA, DiLeone RJ, Parada LF, Nestler EJ, Self DW.

Biol Psychiatry. 2009 Apr 15;65(8):696-701. doi: 10.1016/j.biopsych.2008.09.032. Epub 2008 Nov 6.

27.

Increased impulsivity during withdrawal from cocaine self-administration: role for DeltaFosB in the orbitofrontal cortex.

Winstanley CA, Bachtell RK, Theobald DE, Laali S, Green TA, Kumar A, Chakravarty S, Self DW, Nestler EJ.

Cereb Cortex. 2009 Feb;19(2):435-44. doi: 10.1093/cercor/bhn094. Epub 2008 Jun 6.

28.

Role of GluR1 expression in nucleus accumbens neurons in cocaine sensitization and cocaine-seeking behavior.

Bachtell RK, Choi KH, Simmons DL, Falcon E, Monteggia LM, Neve RL, Self DW.

Eur J Neurosci. 2008 May;27(9):2229-40. doi: 10.1111/j.1460-9568.2008.06199.x. Epub 2008 Apr 22.

PMID:
18430032
29.

Withdrawal from cocaine self-administration normalizes deficits in proliferation and enhances maturity of adult-generated hippocampal neurons.

Noonan MA, Choi KH, Self DW, Eisch AJ.

J Neurosci. 2008 Mar 5;28(10):2516-26. doi: 10.1523/JNEUROSCI.4661-07.2008.

30.

Distinct patterns of DeltaFosB induction in brain by drugs of abuse.

Perrotti LI, Weaver RR, Robison B, Renthal W, Maze I, Yazdani S, Elmore RG, Knapp DJ, Selley DE, Martin BR, Sim-Selley L, Bachtell RK, Self DW, Nestler EJ.

Synapse. 2008 May;62(5):358-69. doi: 10.1002/syn.20500.

31.

Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions.

Krishnan V, Han MH, Graham DL, Berton O, Renthal W, Russo SJ, Laplant Q, Graham A, Lutter M, Lagace DC, Ghose S, Reister R, Tannous P, Green TA, Neve RL, Chakravarty S, Kumar A, Eisch AJ, Self DW, Lee FS, Tamminga CA, Cooper DC, Gershenfeld HK, Nestler EJ.

Cell. 2007 Oct 19;131(2):391-404.

32.

DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction.

Winstanley CA, LaPlant Q, Theobald DE, Green TA, Bachtell RK, Perrotti LI, DiLeone RJ, Russo SJ, Garth WJ, Self DW, Nestler EJ.

J Neurosci. 2007 Sep 26;27(39):10497-507.

33.

Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse.

Graham DL, Edwards S, Bachtell RK, DiLeone RJ, Rios M, Self DW.

Nat Neurosci. 2007 Aug;10(8):1029-37. Epub 2007 Jul 8.

PMID:
17618281
34.

Region-specific tolerance to cocaine-regulated cAMP-dependent protein phosphorylation following chronic self-administration.

Edwards S, Graham DL, Bachtell RK, Self DW.

Eur J Neurosci. 2007 Apr;25(7):2201-13.

PMID:
17439498
35.

IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates.

Russo SJ, Bolanos CA, Theobald DE, DeCarolis NA, Renthal W, Kumar A, Winstanley CA, Renthal NE, Wiley MD, Self DW, Russell DS, Neve RL, Eisch AJ, Nestler EJ.

Nat Neurosci. 2007 Jan;10(1):93-9. Epub 2006 Dec 3.

PMID:
17143271
36.

Differential ability of D1 and D2 dopamine receptor agonists to induce and modulate expression and reinstatement of cocaine place preference in rats.

Graham DL, Hoppenot R, Hendryx A, Self DW.

Psychopharmacology (Berl). 2007 Apr;191(3):719-30. Epub 2006 Jul 12.

PMID:
16835769
37.

Enhanced acquisition of cocaine self-administration by increasing percentages of C57BL/6J genes in mice with a nonpreferring outbred background.

Ruiz-Durántez E, Hall SK, Steffen C, Self DW.

Psychopharmacology (Berl). 2006 Jul;186(4):553-60. Epub 2006 Apr 4.

PMID:
16586086
38.

Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration.

Edwards S, Whisler KN, Fuller DC, Orsulak PJ, Self DW.

Neuropsychopharmacology. 2007 Feb;32(2):354-66. Epub 2006 Mar 15.

39.

Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress.

Berton O, McClung CA, Dileone RJ, Krishnan V, Renthal W, Russo SJ, Graham D, Tsankova NM, Bolanos CA, Rios M, Monteggia LM, Self DW, Nestler EJ.

Science. 2006 Feb 10;311(5762):864-8.

40.

Monogamy: dopamine ties the knot.

Edwards S, Self DW.

Nat Neurosci. 2006 Jan;9(1):7-8. No abstract available.

PMID:
16378085
41.

Antisense-induced reduction in nucleus accumbens cyclic AMP response element binding protein attenuates cocaine reinforcement.

Choi KH, Whisler K, Graham DL, Self DW.

Neuroscience. 2006;137(2):373-83. Epub 2005 Dec 15.

PMID:
16359811
42.

Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum.

Kumar A, Choi KH, Renthal W, Tsankova NM, Theobald DE, Truong HT, Russo SJ, Laplant Q, Sasaki TS, Whistler KN, Neve RL, Self DW, Nestler EJ.

Neuron. 2005 Oct 20;48(2):303-14.

43.

Effects of intra-nucleus accumbens shell administration of dopamine agonists and antagonists on cocaine-taking and cocaine-seeking behaviors in the rat.

Bachtell RK, Whisler K, Karanian D, Self DW.

Psychopharmacology (Berl). 2005 Nov;183(1):41-53. Epub 2005 Oct 22.

PMID:
16163523
44.

Molecular and genetic approaches for behavioral analysis of protein function.

Self DW.

Biol Psychiatry. 2005 Jun 15;57(12):1479-84. Review.

PMID:
15953483
45.

Regulation of drug reward by cAMP response element-binding protein: evidence for two functionally distinct subregions of the ventral tegmental area.

Olson VG, Zabetian CP, Bolanos CA, Edwards S, Barrot M, Eisch AJ, Hughes T, Self DW, Neve RL, Nestler EJ.

J Neurosci. 2005 Jun 8;25(23):5553-62.

46.

DeltaFosB accumulates in a GABAergic cell population in the posterior tail of the ventral tegmental area after psychostimulant treatment.

Perrotti LI, Bolaños CA, Choi KH, Russo SJ, Edwards S, Ulery PG, Wallace DL, Self DW, Nestler EJ, Barrot M.

Eur J Neurosci. 2005 May;21(10):2817-24.

PMID:
15926929
47.
48.

Extinction training regulates neuroadaptive responses to withdrawal from chronic cocaine self-administration.

Self DW, Choi KH, Simmons D, Walker JR, Smagula CS.

Learn Mem. 2004 Sep-Oct;11(5):648-57. Review.

49.
50.

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