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Items: 12

1.

Enhanced proliferation of pancreatic acinar cells in MRL/MpJ mice is driven by severe acinar injury but independent of inflammation.

Bombardo M, Malagola E, Chen R, Carta A, Seleznik GM, Hills AP, Graf R, Sonda S.

Sci Rep. 2018 Jun 20;8(1):9391. doi: 10.1038/s41598-018-27422-0.

2.

Class I histone deacetylase inhibition improves pancreatitis outcome by limiting leukocyte recruitment and acinar-to-ductal metaplasia.

Bombardo M, Saponara E, Malagola E, Chen R, Seleznik GM, Haumaitre C, Quilichini E, Zabel A, Reding T, Graf R, Sonda S.

Br J Pharmacol. 2017 Nov;174(21):3865-3880. doi: 10.1111/bph.13984. Epub 2017 Sep 20.

3.

Development of autoimmune pancreatitis is independent of CDKN1A/p21-mediated pancreatic inflammation.

Seleznik GM, Reding T, Peter L, Gupta A, Steiner SG, Sonda S, Verbeke CS, Dejardin E, Khatkov I, Segerer S, Heikenwalder M, Graf R.

Gut. 2018 Sep;67(9):1663-1673. doi: 10.1136/gutjnl-2016-313458. Epub 2017 Aug 3.

PMID:
28774888
4.

Inactivation of TGFβ receptor II signalling in pancreatic epithelial cells promotes acinar cell proliferation, acinar-to-ductal metaplasia and fibrosis during pancreatitis.

Grabliauskaite K, Saponara E, Reding T, Bombardo M, Seleznik GM, Malagola E, Zabel A, Faso C, Sonda S, Graf R.

J Pathol. 2016 Feb;238(3):434-45. doi: 10.1002/path.4666. Epub 2015 Nov 28.

PMID:
26510396
5.

Serotonin promotes acinar dedifferentiation following pancreatitis-induced regeneration in the adult pancreas.

Saponara E, Grabliauskaite K, Bombardo M, Buzzi R, Silva AB, Malagola E, Tian Y, Hehl AB, Schraner EM, Seleznik GM, Zabel A, Reding T, Sonda S, Graf R.

J Pathol. 2015 Dec;237(4):495-507. doi: 10.1002/path.4595. Epub 2015 Sep 10.

6.

p21(WAF1) (/Cip1) limits senescence and acinar-to-ductal metaplasia formation during pancreatitis.

Grabliauskaite K, Hehl AB, Seleznik GM, Saponara E, Schlesinger K, Zuellig RA, Dittmann A, Bain M, Reding T, Sonda S, Graf R.

J Pathol. 2015 Feb;235(3):502-14. doi: 10.1002/path.4440. Epub 2014 Nov 6.

7.

The role of lymphotoxin signaling in the development of autoimmune pancreatitis and associated secondary extra-pancreatic pathologies.

Seleznik GM, Zoller J, O'Connor T, Graf R, Heikenwalder M.

Cytokine Growth Factor Rev. 2014 Apr;25(2):125-37. doi: 10.1016/j.cytogfr.2014.01.003. Epub 2014 Jan 10. Review.

PMID:
24508087
8.

Nonredundant function of soluble LTα3 produced by innate lymphoid cells in intestinal homeostasis.

Kruglov AA, Grivennikov SI, Kuprash DV, Winsauer C, Prepens S, Seleznik GM, Eberl G, Littman DR, Heikenwalder M, Tumanov AV, Nedospasov SA.

Science. 2013 Dec 6;342(6163):1243-6. doi: 10.1126/science.1243364.

9.

Lymphotoxin β receptor signaling promotes development of autoimmune pancreatitis.

Seleznik GM, Reding T, Romrig F, Saito Y, Mildner A, Segerer S, Sun LK, Regenass S, Lech M, Anders HJ, McHugh D, Kumagi T, Hiasa Y, Lackner C, Haybaeck J, Angst E, Perren A, Balmer ML, Slack E, MacPherson A, Manz MG, Weber A, Browning JL, Arkan MC, Rülicke T, Aguzzi A, Prinz M, Graf R, Heikenwalder M.

Gastroenterology. 2012 Nov;143(5):1361-1374. doi: 10.1053/j.gastro.2012.07.112. Epub 2012 Aug 2.

10.

Lymphotoxin's link to carcinogenesis: friend or foe? from lymphoid neogenesis to hepatocellular carcinoma and prostate cancer.

Wolf MJ, Seleznik GM, Heikenwalder M.

Adv Exp Med Biol. 2011;691:231-49. doi: 10.1007/978-1-4419-6612-4_24. No abstract available.

PMID:
21153327
11.

The unexpected role of lymphotoxin beta receptor signaling in carcinogenesis: from lymphoid tissue formation to liver and prostate cancer development.

Wolf MJ, Seleznik GM, Zeller N, Heikenwalder M.

Oncogene. 2010 Sep 9;29(36):5006-18. doi: 10.1038/onc.2010.260. Epub 2010 Jul 5. Review.

PMID:
20603617
12.

TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer.

Bettermann K, Vucur M, Haybaeck J, Koppe C, Janssen J, Heymann F, Weber A, Weiskirchen R, Liedtke C, Gassler N, Müller M, de Vos R, Wolf MJ, Boege Y, Seleznik GM, Zeller N, Erny D, Fuchs T, Zoller S, Cairo S, Buendia MA, Prinz M, Akira S, Tacke F, Heikenwalder M, Trautwein C, Luedde T.

Cancer Cell. 2010 May 18;17(5):481-96. doi: 10.1016/j.ccr.2010.03.021.

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