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Items: 1 to 50 of 534

1.

Impact of endoscopic submucosal dissection of an anal squamous intraepithelial lesion with indistinct border.

Kasuga K, Saito Y, Wu SYS, Takamaru H, Sakamoto T, Sekine S, Uraoka T.

Endoscopy. 2019 Sep 17. doi: 10.1055/a-0977-2446. [Epub ahead of print] No abstract available.

PMID:
31529437
2.

PINK1 import regulation at a crossroad of mitochondrial fate.

Sekine S.

J Biochem. 2019 Sep 4. pii: mvz069. doi: 10.1093/jb/mvz069. [Epub ahead of print]

PMID:
31504668
3.

Diagnostic yield of the Japan NBI Expert Team (JNET) classification for endoscopic diagnosis of superficial colorectal neoplasms in a large-scale clinical practice database.

Kobayashi S, Yamada M, Takamaru H, Sakamoto T, Matsuda T, Sekine S, Igarashi Y, Saito Y.

United European Gastroenterol J. 2019 Aug;7(7):914-923. doi: 10.1177/2050640619845987. Epub 2019 Apr 26.

4.

Evolving Vision of Regulatory Science in the Global Medical Community.

Kondo T, Hayashi Y, Sato J, Sekine S, Hoshino T, Sato D.

Clin Pharmacol Ther. 2019 Aug 2. doi: 10.1002/cpt.1604. [Epub ahead of print] Review.

PMID:
31376148
5.

In vitro bile acid-dependent hepatocyte toxicity assay system using human induced pluripotent stem cell-derived hepatocytes: Current status and disadvantages to overcome.

Sakai Y, Iwao T, Susukida T, Nukaga T, Takemura A, Sekine S, Ito K, Matsunaga T.

Drug Metab Pharmacokinet. 2019 Aug;34(4):264-271. doi: 10.1016/j.dmpk.2019.04.004. Epub 2019 May 10.

PMID:
31285099
6.

All-in-one microfluidic device for on-site diagnosis of pathogens based on an integrated continuous flow PCR and electrophoresis biochip.

Li Z, Ju R, Sekine S, Zhang D, Zhuang S, Yamaguchi Y.

Lab Chip. 2019 Aug 21;19(16):2663-2668. doi: 10.1039/c9lc00305c. Epub 2019 Jul 5.

PMID:
31273367
7.

Identification of a novel PRR15L-RSPO2 fusion transcript in a sigmoid colon cancer derived from superficially serrated adenoma.

Mizuguchi Y, Sakamoto T, Hashimoto T, Tsukamoto S, Iwasa S, Saito Y, Sekine S.

Virchows Arch. 2019 Jun 17. doi: 10.1007/s00428-019-02604-x. [Epub ahead of print]

PMID:
31209633
8.

Establishment of Novel Gastric Cancer Patient-Derived Xenografts and Cell Lines: Pathological Comparison between Primary Tumor, Patient-Derived, and Cell-Line Derived Xenografts.

Kuwata T, Yanagihara K, Iino Y, Komatsu T, Ochiai A, Sekine S, Taniguchi H, Katai H, Kinoshita T, Ohtsu A.

Cells. 2019 Jun 14;8(6). pii: E585. doi: 10.3390/cells8060585.

9.

A case of mixed-type early gastric cancer with recurrence following curative endoscopic submucosal dissection for expanded indication.

Kobayashi S, Nonaka S, Oda I, Abe S, Suzuki H, Yoshinaga S, Taniguchi H, Sekine S, Igarashi Y, Saito Y.

Endosc Int Open. 2019 Jun;7(6):E841-E845. doi: 10.1055/a-0900-3835. Epub 2019 Jun 12.

10.

Recurrent YAP1-MAML2 and YAP1-NUTM1 fusions in poroma and porocarcinoma.

Sekine S, Kiyono T, Ryo E, Ogawa R, Wakai S, Ichikawa H, Suzuki K, Arai S, Tsuta K, Ishida M, Sasajima Y, Goshima N, Yamazaki N, Mori T.

J Clin Invest. 2019 May 30;130:3827-3832. doi: 10.1172/JCI126185.

11.

Inhibition of biliary network reconstruction by benzbromarone delays recovery from pre-existing liver injury.

Takemura A, Gong S, Sekine S, Ito K.

Toxicology. 2019 Jul 1;423:32-41. doi: 10.1016/j.tox.2019.05.004. Epub 2019 May 15.

PMID:
31102694
12.

A Multicenter Study of the Prognostic Value of Desmoplastic Reaction Categorization in Stage II Colorectal Cancer.

Ueno H, Kanemitsu Y, Sekine S, Ishiguro M, Ito E, Hashiguchi Y, Kondo F, Shimazaki H, Kajiwara Y, Okamoto K, Mochizuki S, Tsujimoto H, Shinto E.

Am J Surg Pathol. 2019 Aug;43(8):1015-1022. doi: 10.1097/PAS.0000000000001272.

PMID:
31094924
13.

Cancer cell niche factors secreted from cancer-associated fibroblast by loss of H3K27me3.

Maeda M, Takeshima H, Iida N, Hattori N, Yamashita S, Moro H, Yasukawa Y, Nishiyama K, Hashimoto T, Sekine S, Ishii G, Ochiai A, Fukagawa T, Katai H, Sakai Y, Ushijima T.

Gut. 2019 May 13. pii: gutjnl-2018-317645. doi: 10.1136/gutjnl-2018-317645. [Epub ahead of print]

PMID:
31085554
14.

Nanopore Formation in the Cuticle of an Insect Olfactory Sensillum.

Ando T, Sekine S, Inagaki S, Misaki K, Badel L, Moriya H, Sami MM, Itakura Y, Chihara T, Kazama H, Yonemura S, Hayashi S.

Curr Biol. 2019 May 6;29(9):1512-1520.e6. doi: 10.1016/j.cub.2019.03.043. Epub 2019 Apr 18.

PMID:
31006566
15.

Functional evaluation of PDGFB-variants in idiopathic basal ganglia calcification, using patient-derived iPS cells.

Sekine SI, Kaneko M, Tanaka M, Ninomiya Y, Kurita H, Inden M, Yamada M, Hayashi Y, Inuzuka T, Mitsui J, Ishiura H, Iwata A, Fujigasaki H, Tamaki H, Tamaki R, Kito S, Taguchi Y, Tanaka K, Atsuta N, Sobue G, Kondo T, Inoue H, Tsuji S, Hozumi I.

Sci Rep. 2019 Apr 5;9(1):5698. doi: 10.1038/s41598-019-42115-y.

16.

EIF3E-RSPO2 and PIEZO1-RSPO2 fusions in colorectal traditional serrated adenoma.

Hashimoto T, Ogawa R, Yoshida H, Taniguchi H, Kojima M, Saito Y, Sekine S.

Histopathology. 2019 Aug;75(2):266-273. doi: 10.1111/his.13867. Epub 2019 Jun 20.

PMID:
30916365
17.

Risk of Lymph Node Metastasis in Patients with the Superficial Spreading Type of Esophageal Squamous Cell Carcinoma.

Yachida T, Oda I, Abe S, Sekiguchi M, Nonaka S, Suzuki H, Yoshinaga S, Taniguchi H, Sekine S, Masugata H, Masaki T, Daiko H, Saito Y.

Digestion. 2019 Mar 25:1-6. doi: 10.1159/000499017. [Epub ahead of print]

PMID:
30909271
18.

Feasibility and utility of a panel testing for 114 cancer-associated genes in a clinical setting: A hospital-based study.

Sunami K, Ichikawa H, Kubo T, Kato M, Fujiwara Y, Shimomura A, Koyama T, Kakishima H, Kitami M, Matsushita H, Furukawa E, Narushima D, Nagai M, Taniguchi H, Motoi N, Sekine S, Maeshima A, Mori T, Watanabe R, Yoshida M, Yoshida A, Yoshida H, Satomi K, Sukeda A, Hashimoto T, Shimizu T, Iwasa S, Yonemori K, Kato K, Morizane C, Ogawa C, Tanabe N, Sugano K, Hiraoka N, Tamura K, Yoshida T, Fujiwara Y, Ochiai A, Yamamoto N, Kohno T.

Cancer Sci. 2019 Apr;110(4):1480-1490. doi: 10.1111/cas.13969. Epub 2019 Apr 2.

19.

Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.

Ehara H, Kujirai T, Fujino Y, Shirouzu M, Kurumizaka H, Sekine SI.

Science. 2019 Feb 15;363(6428):744-747. doi: 10.1126/science.aav8912. Epub 2019 Feb 7.

PMID:
30733384
20.

Reciprocal Roles of Tom7 and OMA1 during Mitochondrial Import and Activation of PINK1.

Sekine S, Wang C, Sideris DP, Bunker E, Zhang Z, Youle RJ.

Mol Cell. 2019 Mar 7;73(5):1028-1043.e5. doi: 10.1016/j.molcel.2019.01.002. Epub 2019 Feb 4.

PMID:
30733118
21.

SLC20A2 variants cause dysfunctional phosphate transport activity in endothelial cells induced from Idiopathic Basal Ganglia Calcification patients-derived iPSCs.

Sekine SI, Nishii K, Masaka T, Kurita H, Inden M, Hozumi I.

Biochem Biophys Res Commun. 2019 Mar 5;510(2):303-308. doi: 10.1016/j.bbrc.2019.01.096. Epub 2019 Jan 28.

PMID:
30704756
22.

Frequent mutations of genes encoding vacuolar H+ -ATPase components in granular cell tumors.

Sekimizu M, Yoshida A, Mitani S, Asano N, Hirata M, Kubo T, Yamazaki F, Sakamoto H, Kato M, Makise N, Mori T, Yamazaki N, Sekine S, Oda I, Watanabe SI, Hiraga H, Yonemoto T, Kawamoto T, Naka N, Funauchi Y, Nishida Y, Honoki K, Kawano H, Tsuchiya H, Kunisada T, Matsuda K, Inagaki K, Kawai A, Ichikawa H.

Genes Chromosomes Cancer. 2019 Jun;58(6):373-380. doi: 10.1002/gcc.22727. Epub 2019 Jan 21.

PMID:
30597645
23.

Author Correction: The selective tRNA aminoacylation mechanism based on a single G•U pair.

Naganuma M, Sekine SI, Chong YE, Guo M, Yang XL, Gamper H, Hou YM, Schimmel P, Yokoyama S.

Nature. 2018 Dec;564(7736):E37. doi: 10.1038/s41586-018-0760-4.

24.

RHOA mutations and CLDN18-ARHGAP fusions in intestinal-type adenocarcinoma with anastomosing glands of the stomach.

Hashimoto T, Ogawa R, Tang TY, Yoshida H, Taniguchi H, Katai H, Oda I, Sekine S.

Mod Pathol. 2019 Apr;32(4):568-575. doi: 10.1038/s41379-018-0181-9. Epub 2018 Nov 13.

PMID:
30425335
25.

Mediastinoscopic salvage esophagectomy for recurrent esophageal squamous cell carcinoma after definitive chemoradiotherapy in a previously pneumonectomized patient.

Okumura T, Seto Y, Aikou S, Moriyama M, Sekine S, Hashimoto I, Shibuya K, Hojo S, Yoshioka I, Nagata T, Fujii T.

Asian J Endosc Surg. 2018 Nov 8. doi: 10.1111/ases.12658. [Epub ahead of print]

PMID:
30411514
26.

Synthesis of novel benzbromarone derivatives designed to avoid metabolic activation.

Ohe T, Umezawa R, Kitagawara Y, Yasuda D, Takahashi K, Nakamura S, Abe A, Sekine S, Ito K, Okunushi K, Morio H, Furihata T, Anzai N, Mashino T.

Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3708-3711. doi: 10.1016/j.bmcl.2018.10.023. Epub 2018 Oct 15.

PMID:
30389287
27.

Structural basis of the nucleosome transition during RNA polymerase II passage.

Kujirai T, Ehara H, Fujino Y, Shirouzu M, Sekine SI, Kurumizaka H.

Science. 2018 Nov 2;362(6414):595-598. doi: 10.1126/science.aau9904. Epub 2018 Oct 4.

PMID:
30287617
28.

Acquisition of WNT Pathway Gene Alterations Coincides With the Transition From Precursor Polyps to Traditional Serrated Adenomas.

Hashimoto T, Ogawa R, Yoshida H, Taniguchi H, Kojima M, Saito Y, Sekine S.

Am J Surg Pathol. 2019 Jan;43(1):132-139. doi: 10.1097/PAS.0000000000001149.

PMID:
30179900
29.

Divergent Routes toward Wnt and R-spondin Niche Independency during Human Gastric Carcinogenesis.

Nanki K, Toshimitsu K, Takano A, Fujii M, Shimokawa M, Ohta Y, Matano M, Seino T, Nishikori S, Ishikawa K, Kawasaki K, Togasaki K, Takahashi S, Sukawa Y, Ishida H, Sugimoto S, Kawakubo H, Kim J, Kitagawa Y, Sekine S, Koo BK, Kanai T, Sato T.

Cell. 2018 Aug 9;174(4):856-869.e17. doi: 10.1016/j.cell.2018.07.027.

30.

Distinct ways of G:U recognition by conserved tRNA binding motifs.

Chong YE, Guo M, Yang XL, Kuhle B, Naganuma M, Sekine SI, Yokoyama S, Schimmel P.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):7527-7532. doi: 10.1073/pnas.1807109115. Epub 2018 Jul 2.

31.

The stress response gene ATF3 is a direct target of the Wnt/β-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells.

Inoue M, Uchida Y, Edagawa M, Hirata M, Mitamura J, Miyamoto D, Taketani K, Sekine S, Kawauchi J, Kitajima S.

PLoS One. 2018 Jul 2;13(7):e0194160. doi: 10.1371/journal.pone.0194160. eCollection 2018.

32.

Reappraisal of the genetic heterogeneity of sessile serrated adenoma/polyp.

Cho H, Hashimoto T, Yoshida H, Taniguchi H, Ogawa R, Mori T, Hiraoka N, Saito Y, Sekine S.

Histopathology. 2018 Oct;73(4):672-680. doi: 10.1111/his.13688. Epub 2018 Aug 2.

PMID:
29920740
33.

Slow luminescence kinetics of semi-synthetic aequorin: expression, purification and structure determination of cf3-aequorin.

Inouye S, Tomabechi Y, Hosoya T, Sekine SI, Shirouzu M.

J Biochem. 2018 Sep 1;164(3):247-255. doi: 10.1093/jb/mvy049.

PMID:
29796619
34.

Superficially serrated adenoma: a proposal for a novel subtype of colorectal serrated lesion.

Hashimoto T, Tanaka Y, Ogawa R, Mori T, Yoshida H, Taniguchi H, Hiraoka N, Kojima M, Oono Y, Saito Y, Sekine S.

Mod Pathol. 2018 Oct;31(10):1588-1598. doi: 10.1038/s41379-018-0069-8. Epub 2018 May 22.

PMID:
29789649
35.

Increased susceptibility to troglitazone-induced mitochondrial permeability transition in type 2 diabetes mellitus model rat.

Segawa M, Sekine S, Sato T, Ito K.

J Toxicol Sci. 2018;43(5):339-351. doi: 10.2131/jts.43.339.

36.

Relationship between the burden of major periodontal bacteria and serum lipid profile in a cross-sectional Japanese study.

Choi YH, Kosaka T, Ojima M, Sekine S, Kokubo Y, Watanabe M, Miyamoto Y, Ono T, Amano A.

BMC Oral Health. 2018 May 4;18(1):77. doi: 10.1186/s12903-018-0536-0.

37.

Pilot study on probe-based confocal laser endomicroscopy for colorectal neoplasms: an initial experience in Japan.

Abe S, Saito Y, Oono Y, Tanaka Y, Sakamoto T, Yamada M, Nakajima T, Matsuda T, Ikematsu H, Yano T, Sekine S, Kojima M, Yamagishi H, Kato H.

Int J Colorectal Dis. 2018 Aug;33(8):1071-1078. doi: 10.1007/s00384-018-3059-x. Epub 2018 Apr 26.

PMID:
29700599
38.

Inorganic phosphorus (Pi) in CSF is a biomarker for SLC20A2-associated idiopathic basal ganglia calcification (IBGC1).

Hozumi I, Kurita H, Ozawa K, Furuta N, Inden M, Sekine SI, Yamada M, Hayashi Y, Kimura A, Inuzuka T, Seishima M.

J Neurol Sci. 2018 May 15;388:150-154. doi: 10.1016/j.jns.2018.03.014. Epub 2018 Mar 8.

PMID:
29627011
39.

Architecture of the RNA polymerase II elongation complex: new insights into Spt4/5 and Elf1.

Ehara H, Sekine SI.

Transcription. 2018;9(5):286-291. doi: 10.1080/21541264.2018.1454817. Epub 2018 May 7. Review.

40.

Structural Basis of Heterochromatin Formation by Human HP1.

Machida S, Takizawa Y, Ishimaru M, Sugita Y, Sekine S, Nakayama JI, Wolf M, Kurumizaka H.

Mol Cell. 2018 Feb 1;69(3):385-397.e8. doi: 10.1016/j.molcel.2017.12.011. Epub 2018 Jan 11.

41.

PINK1 import regulation; a fine system to convey mitochondrial stress to the cytosol.

Sekine S, Youle RJ.

BMC Biol. 2018 Jan 10;16(1):2. doi: 10.1186/s12915-017-0470-7. Review.

42.

Predictive relevance of lymphovascular invasion in T1 colorectal cancer before endoscopic treatment.

Inoki K, Sakamoto T, Takamaru H, Sekiguchi M, Yamada M, Nakajima T, Matsuda T, Taniguchi H, Sekine S, Kanemitsu Y, Ohe Y, Saito Y.

Endosc Int Open. 2017 Dec;5(12):E1278-E1283. doi: 10.1055/s-0043-117952. Epub 2017 Dec 6.

43.

Automated histological classification of whole slide images of colorectal biopsy specimens.

Yoshida H, Yamashita Y, Shimazu T, Cosatto E, Kiyuna T, Taniguchi H, Sekine S, Ochiai A.

Oncotarget. 2017 Oct 12;8(53):90719-90729. doi: 10.18632/oncotarget.21819. eCollection 2017 Oct 31.

44.

Feasibility of endoscopic resection using bipolar snare for nonampullary duodenal tumours in familial adenomatous polyposis patients.

Inoki K, Nakajima T, Nonaka S, Abe S, Suzuki H, Yoshinaga S, Oda I, Yamada M, Takatsu M, Yoshida H, Taniguchi H, Sekine S, Ohe Y, Saito Y.

Fam Cancer. 2018 Oct;17(4):517-524. doi: 10.1007/s10689-017-0063-1.

PMID:
29189961
45.

A Thermus phage protein inhibits host RNA polymerase by preventing template DNA strand loading during open promoter complex formation.

Ooi WY, Murayama Y, Mekler V, Minakhin L, Severinov K, Yokoyama S, Sekine SI.

Nucleic Acids Res. 2018 Jan 9;46(1):431-441. doi: 10.1093/nar/gkx1162.

46.

Disentangling the prognostic heterogeneity of stage III colorectal cancer through histologic stromal categorization.

Ueno H, Sekine S, Oshiro T, Kanemitsu Y, Hamaguchi T, Shida D, Takashima A, Ishiguro M, Ito E, Hashiguchi Y, Kondo F, Shimazaki H, Mochizuki S, Kajiwara Y, Shinto E, Yamamoto J, Shimada Y.

Surgery. 2018 Apr;163(4):777-783. doi: 10.1016/j.surg.2017.09.007. Epub 2017 Nov 20.

PMID:
29162344
47.

Evaluation of immune-mediated idiosyncratic drug toxicity using chimeric HLA transgenic mice.

Susukida T, Aoki S, Kogo K, Fujimori S, Song B, Liu C, Sekine S, Ito K.

Arch Toxicol. 2018 Mar;92(3):1177-1188. doi: 10.1007/s00204-017-2112-9. Epub 2017 Nov 17.

PMID:
29150704
48.

[I. Key Points of the Guidelines for Clinical Practice of Hereditary Colorectal Cancer].

Ishida H, Yamaguchi T, Tanakaya K, Akagi K, Sekine S, Shimodaira H, Tomita N, Sugihara K, Watanabe T.

Gan To Kagaku Ryoho. 2017 Nov;44(11):986-989. Japanese. No abstract available.

PMID:
29138373
49.

Quantitative Detection of Ethanol/Acetone in Complex Solutions Using Raman Spectroscopy Based on Headspace Gas Analysis.

Zhao Y, Yamaguchi Y, Liu C, Sekine S, Dou X.

Appl Spectrosc. 2018 Feb;72(2):280-287. doi: 10.1177/0003702817738010. Epub 2017 Oct 30.

PMID:
29082758
50.

SOX10 Expression as Well as BRAF and GNAQ/11 Mutations Distinguish Pigmented Ciliary Epithelium Neoplasms From Uveal Melanomas.

Mori T, Sukeda A, Sekine S, Shibata S, Ryo E, Okano H, Suzuki S, Hiraoka N.

Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5445-5451. doi: 10.1167/iovs.17-22362.

PMID:
29059311

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