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Items: 1 to 50 of 201

1.

Kupffer Cell TLR2/3 Signaling: A Pathway for EGCG Amelioration of Ethanol-Induced Hepatic Injury.

Czech TY, Seki E.

Cell Mol Gastroenterol Hepatol. 2019 Oct 26. pii: S2352-345X(19)30137-7. doi: 10.1016/j.jcmgh.2019.10.001. [Epub ahead of print] No abstract available.

2.

Tracheal cartilaginous sleeve in patients with Beare-Stevenson syndrome.

Seki E, Enomoto K, Tanoue K, Tanaka M, Kurosawa K.

Congenit Anom (Kyoto). 2019 Aug 1. doi: 10.1111/cga.12352. [Epub ahead of print] No abstract available.

PMID:
31373082
3.

Murine macrophage autophagy protects against alcohol-induced liver injury by degrading interferon regulatory factor 1 (IRF1) and removing damaged mitochondria.

Liang S, Zhong Z, Kim SY, Uchiyama R, Roh YS, Matsushita H, Gottlieb RA, Seki E.

J Biol Chem. 2019 Aug 16;294(33):12359-12369. doi: 10.1074/jbc.RA119.007409. Epub 2019 Jun 24.

PMID:
31235522
4.

Alcoholic liver disease: A current molecular and clinical perspective.

Ohashi K, Pimienta M, Seki E.

Liver Res. 2018 Dec;2(4):161-172. doi: 10.1016/j.livres.2018.11.002. Epub 2018 Dec 12.

5.

Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis.

Yang YM, Noureddin M, Liu C, Ohashi K, Kim SY, Ramnath D, Powell EE, Sweet MJ, Roh YS, Hsin IF, Deng N, Liu Z, Liang J, Mena E, Shouhed D, Schwabe RF, Jiang D, Lu SC, Noble PW, Seki E.

Sci Transl Med. 2019 Jun 12;11(496). pii: eaat9284. doi: 10.1126/scitranslmed.aat9284.

PMID:
31189722
6.

Glial cell line-derived neurotrophic factor (GDNF) mediates hepatic stellate cell activation via ALK5/Smad signalling.

Tao L, Ma W, Wu L, Xu M, Yang Y, Zhang W, Sha W, Li H, Xu J, Feng R, Xue D, Zhang J, Dooley S, Seki E, Liu P, Liu C.

Gut. 2019 Dec;68(12):2214-2227. doi: 10.1136/gutjnl-2018-317872. Epub 2019 Jun 6.

7.

NOD-like receptor C4 Inflammasome Regulates the Growth of Colon Cancer Liver Metastasis in NAFLD.

Ohashi K, Wang Z, Yang YM, Billet S, Tu W, Pimienta M, Cassel SL, Pandol SJ, Lu SC, Sutterwala FS, Bhowmick N, Seki E.

Hepatology. 2019 Nov;70(5):1582-1599. doi: 10.1002/hep.30693. Epub 2019 May 23.

PMID:
31044438
8.

Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.

Yanagisawa T, Kuratani M, Seki E, Hino N, Sakamoto K, Yokoyama S.

Cell Chem Biol. 2019 Jul 18;26(7):936-949.e13. doi: 10.1016/j.chembiol.2019.03.008. Epub 2019 Apr 25.

PMID:
31031143
9.

Inflammation and Liver Cancer: Molecular Mechanisms and Therapeutic Targets.

Yang YM, Kim SY, Seki E.

Semin Liver Dis. 2019 Feb;39(1):26-42. doi: 10.1055/s-0038-1676806. Epub 2019 Jan 17. Review.

PMID:
30809789
10.

Intestinal Lipolysis Mitigates Nonalcoholic Fatty Liver Disease: New Roles for Carboxylesterase 2c in the Intestine.

Pimienta M, Beletsky A, Seki E.

Hepatol Commun. 2019 Feb 1;3(2):177-179. doi: 10.1002/hep4.1318. eCollection 2019 Feb.

11.

MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment.

Wang P, Song X, Utpatel K, Shang R, Yang YM, Xu M, Zhang J, Che L, Gordan J, Cigliano A, Seki E, Evert M, Calvisi DF, Hu X, Chen X.

Cell Death Dis. 2019 Feb 11;10(2):120. doi: 10.1038/s41419-019-1389-4.

12.

Cell-Free Protein Synthesis Using S30 Extracts from Escherichia coli RFzero Strains for Efficient Incorporation of Non-Natural Amino Acids into Proteins.

Adachi J, Katsura K, Seki E, Takemoto C, Shirouzu M, Terada T, Mukai T, Sakamoto K, Yokoyama S.

Int J Mol Sci. 2019 Jan 24;20(3). pii: E492. doi: 10.3390/ijms20030492.

13.

Immunoreactivity of a G protein-coupled l-DOPA receptor GPR143, in Lewy bodies.

Goshima Y, Watanabe S, Seki E, Koga M, Masukawa D, Nakamura F, Komori T, Arai N.

Neurosci Res. 2019 Nov;148:49-53. doi: 10.1016/j.neures.2018.12.004. Epub 2018 Dec 24.

PMID:
30590075
14.

The mitochondrial chaperone Prohibitin 1 negatively regulates interleukin-8 in human liver cancers.

Yang JW, Murray B, Barbier-Torres L, Liu T, Liu Z, Yang H, Fan W, Wang J, Li Y, Seki E, Mato JM, Lu SC.

J Biol Chem. 2019 Feb 8;294(6):1984-1996. doi: 10.1074/jbc.RA118.004863. Epub 2018 Dec 6.

PMID:
30523154
15.

Gα12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration.

Kim TH, Yang YM, Han CY, Koo JH, Oh H, Kim SS, You BH, Choi YH, Park TS, Lee CH, Kurose H, Noureddin M, Seki E, Wan YY, Choi CS, Kim SG.

J Clin Invest. 2018 Dec 3;128(12):5587-5602. doi: 10.1172/JCI97831. Epub 2018 Nov 12.

16.

Nuclear Receptors: Opening Up New Avenues of Pediatric Fatty Liver Research.

Pandyarajan V, Seki E.

Hepatol Commun. 2018 Oct 1;2(10):1157-1159. doi: 10.1002/hep4.1260. eCollection 2018 Oct. No abstract available.

17.

Integrative genomic analysis of mouse and human hepatocellular carcinoma.

Dow M, Pyke RM, Tsui BY, Alexandrov LB, Nakagawa H, Taniguchi K, Seki E, Harismendy O, Shalapour S, Karin M, Carter H, Font-Burgada J.

Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):E9879-E9888. doi: 10.1073/pnas.1811029115. Epub 2018 Oct 4.

18.

Tumor Suppressor Down-Regulation Promotes Hepatocyte Proliferation: A New GANKster on the Block.

Pimienta M, Seki E.

Cell Mol Gastroenterol Hepatol. 2018 Jul 7;6(3):345-346. doi: 10.1016/j.jcmgh.2018.06.003. eCollection 2018. No abstract available.

19.

MicroRNA-942 mediates hepatic stellate cell activation by regulating BAMBI expression in human liver fibrosis.

Tao L, Xue D, Shen D, Ma W, Zhang J, Wang X, Zhang W, Wu L, Pan K, Yang Y, Nwosu ZC, Dooley S, Seki E, Liu C.

Arch Toxicol. 2018 Sep;92(9):2935-2946. doi: 10.1007/s00204-018-2278-9. Epub 2018 Aug 10.

20.

Interventional Potential of Recombinant Feline Hepatocyte Growth Factor in a Mouse Model of Non-alcoholic Steatohepatitis.

Yang YM, Fukui M, Wang Z, Miao F, Karriker MJ, Seki E.

Front Endocrinol (Lausanne). 2018 Jul 23;9:378. doi: 10.3389/fendo.2018.00378. eCollection 2018.

21.

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.

Zhong Z, Liang S, Sanchez-Lopez E, He F, Shalapour S, Lin XJ, Wong J, Ding S, Seki E, Schnabl B, Hevener AL, Greenberg HB, Kisseleva T, Karin M.

Nature. 2018 Aug;560(7717):198-203. doi: 10.1038/s41586-018-0372-z. Epub 2018 Jul 25.

22.

Chemokines and Chemokine Receptors in the Development of NAFLD.

Roh YS, Seki E.

Adv Exp Med Biol. 2018;1061:45-53. doi: 10.1007/978-981-10-8684-7_4. Review.

PMID:
29956205
23.

Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling.

Dhar D, Antonucci L, Nakagawa H, Kim JY, Glitzner E, Caruso S, Shalapour S, Yang L, Valasek MA, Lee S, Minnich K, Seki E, Tuckermann J, Sibilia M, Zucman-Rossi J, Karin M.

Cancer Cell. 2018 Jun 11;33(6):1061-1077.e6. doi: 10.1016/j.ccell.2018.05.003.

24.

Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer.

Liu T, Yang H, Fan W, Tu J, Li TWH, Wang J, Shen H, Yang J, Xiong T, Steggerda J, Liu Z, Noureddin M, Maldonado SS, Annamalai A, Seki E, Mato JM, Lu SC.

Gastroenterology. 2018 Aug;155(2):557-571.e14. doi: 10.1053/j.gastro.2018.04.032. Epub 2018 May 5.

25.

Astrocyte elevated gene-1 (AEG-1): a new potential therapeutic target for the treatment of nonalcoholic steatohepatitis (NASH).

Wang Q, Seki E.

Hepatobiliary Surg Nutr. 2018 Feb;7(1):44-47. doi: 10.21037/hbsn.2017.11.04. No abstract available.

26.

Cell-Free Protein Synthesis for Multiple Site-Specific Incorporation of Noncanonical Amino Acids Using Cell Extracts from RF-1 Deletion E. coli Strains.

Seki E, Yanagisawa T, Yokoyama S.

Methods Mol Biol. 2018;1728:49-65. doi: 10.1007/978-1-4939-7574-7_3.

PMID:
29404990
27.
28.

[Successful Early Surgical Treatment for Infected Traumatic Pulmonary Pseudocyst].

Goto M, Aoyama K, Seki E, Shimotakahara A, Watarai H, Hirose T, Shimoda M, Haga T.

Kyobu Geka. 2017 Dec;70(13):1075-1078. Japanese.

PMID:
29249785
29.

S-adenosylmethionine and methylthioadenosine inhibit cancer metastasis by targeting microRNA 34a/b-methionine adenosyltransferase 2A/2B axis.

Tomasi ML, Cossu C, Spissu Y, Floris A, Ryoo M, Iglesias-Ara A, Wang Q, Pandol SJ, Bhowmick NA, Seki E, Posadas EM, Lu SC.

Oncotarget. 2017 Aug 12;8(45):78851-78869. doi: 10.18632/oncotarget.20234. eCollection 2017 Oct 3.

30.

The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in hepatocyte-specific TAK1-deleted mice.

Song IJ, Yang YM, Inokuchi-Shimizu S, Roh YS, Yang L, Seki E.

Int J Cancer. 2018 Jan 1;142(1):81-91. doi: 10.1002/ijc.31029. Epub 2017 Sep 23.

31.

TRIF Differentially Regulates Hepatic Steatosis and Inflammation/Fibrosis in Mice.

Yang L, Miura K, Zhang B, Matsushita H, Yang YM, Liang S, Song J, Roh YS, Seki E.

Cell Mol Gastroenterol Hepatol. 2017 Jan 17;3(3):469-483. doi: 10.1016/j.jcmgh.2016.12.004. eCollection 2017 May.

32.

Corrigendum to "Multiple inhibitory factor removal from an Escherichia coli cell extract improves cell-free protein synthesis" [J Biosci Bioeng 108 (2009) 30-35].

Seki E, Matsuda N, Kigawa T.

J Biosci Bioeng. 2017 Jan;123(1):139. doi: 10.1016/j.jbiosc.2016.10.001. Epub 2016 Oct 27. No abstract available.

PMID:
28341143
33.

Acrolein, a New Villain in the Development of Alcoholic Liver Disease.

Seki E.

Cell Mol Gastroenterol Hepatol. 2016 Jul 26;2(5):544-545. doi: 10.1016/j.jcmgh.2016.06.005. eCollection 2016 Sep. No abstract available.

34.

[CLINICAL INVESTIGATION OF 6 CASES OF TUBERCULOUS SPONDYLITIS].

Masuda T, Horiba M, Hirose T, Nakano S, Moroi A, Seki E, Goto M, Haga T, Aoyama K.

Kekkaku. 2016 Nov;91(11-12):709-715. Japanese.

PMID:
30648374
35.

LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis.

Odena G, Chen J, Lozano JJ, Altamirano J, Rodrigo-Torres D, Affo S, Morales-Ibanez O, Matsushita H, Zou J, Dumitru R, Caballeria J, Gines P, Arroyo V, You M, Rautou PE, Valla D, Crews F, Seki E, Sancho-Bru P, Bataller R.

Sci Rep. 2016 Oct 18;6:35610. doi: 10.1038/srep35610.

36.

Corrigendum to ''Cell-free protein synthesis system from Escherichia coli cells cultured at decreased temperatures improves productivity by decreasing DNA template degradation'' [Anal. Biochem. 377 (2008) 156-161].

Seki E, Matsuda N, Yokoyama S, Kigawa T.

Anal Biochem. 2017 Jan 15;517:22. doi: 10.1016/j.ab.2016.09.023. Epub 2016 Nov 2. No abstract available.

PMID:
27712971
37.

Radiographic changes and factors associated with subsequent progression of damage in weight-bearing joints of patients with rheumatoid arthritis under TNF-blocking therapies-three-year observational study.

Matsushita I, Motomura H, Seki E, Kimura T.

Mod Rheumatol. 2017 Jul;27(4):570-575. doi: 10.1080/14397595.2016.1227235. Epub 2016 Sep 26.

PMID:
27589926
38.

p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells.

Umemura A, He F, Taniguchi K, Nakagawa H, Yamachika S, Font-Burgada J, Zhong Z, Subramaniam S, Raghunandan S, Duran A, Linares JF, Reina-Campos M, Umemura S, Valasek MA, Seki E, Yamaguchi K, Koike K, Itoh Y, Diaz-Meco MT, Moscat J, Karin M.

Cancer Cell. 2016 Jun 13;29(6):935-948. doi: 10.1016/j.ccell.2016.04.006. Epub 2016 May 19.

39.

Finding a new role for NEMO: A key player in preventing hepatocyte apoptosis and liver tumorigenesis by inhibiting RIPK1.

Hsin IF, Montano E, Seki E.

Hepatology. 2016 Jul;64(1):295-7. doi: 10.1002/hep.28627. Epub 2016 May 31. Review. No abstract available.

40.

Basic and Clinical Advances in Chronic Liver Inflammation.

Enomoto H, Tamori A, Yoshiji H, Seki E.

Mediators Inflamm. 2016;2016:1571457. doi: 10.1155/2016/1571457. Epub 2016 Feb 24. No abstract available.

41.

Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells.

Siegmund SV, Schlosser M, Schildberg FA, Seki E, De Minicis S, Uchinami H, Kuntzen C, Knolle PA, Strassburg CP, Schwabe RF.

PLoS One. 2016 Mar 3;11(3):e0150893. doi: 10.1371/journal.pone.0150893. eCollection 2016.

42.

Exosome Migration Inhibitory Factor as a Marker and Therapeutic Target for Pancreatic Cancer.

Matsushita H, Yang YM, Pandol SJ, Seki E.

Gastroenterology. 2016 Apr;150(4):1033-5. doi: 10.1053/j.gastro.2016.02.051. Epub 2016 Feb 27. No abstract available.

43.

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.

Zhong Z, Umemura A, Sanchez-Lopez E, Liang S, Shalapour S, Wong J, He F, Boassa D, Perkins G, Ali SR, McGeough MD, Ellisman MH, Seki E, Gustafsson AB, Hoffman HM, Diaz-Meco MT, Moscat J, Karin M.

Cell. 2016 Feb 25;164(5):896-910. doi: 10.1016/j.cell.2015.12.057.

44.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC Jr, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR Jr, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, Ciarcia R, Ciechomska IA, Ciriolo MR, Cirone M, Claerhout S, Clague MJ, Clària J, Clarke PG, Clarke R, Clementi E, Cleyrat C, Cnop M, Coccia EM, Cocco T, Codogno P, Coers J, Cohen EE, Colecchia D, Coletto L, Coll NS, Colucci-Guyon E, Comincini S, Condello M, Cook KL, Coombs GH, Cooper CD, Cooper JM, Coppens I, Corasaniti MT, Corazzari M, Corbalan R, Corcelle-Termeau E, Cordero MD, Corral-Ramos C, Corti O, Cossarizza A, Costelli P, Costes S, Cotman SL, Coto-Montes A, Cottet S, Couve E, Covey LR, Cowart LA, Cox JS, Coxon FP, Coyne CB, Cragg MS, Craven RJ, Crepaldi T, Crespo JL, Criollo A, Crippa V, Cruz MT, Cuervo AM, Cuezva JM, Cui T, Cutillas PR, Czaja MJ, Czyzyk-Krzeska MF, Dagda RK, Dahmen U, Dai C, Dai W, Dai Y, Dalby KN, Dalla Valle L, Dalmasso G, D'Amelio M, Damme M, Darfeuille-Michaud A, Dargemont C, Darley-Usmar VM, Dasarathy S, Dasgupta B, Dash S, Dass CR, Davey HM, Davids LM, Dávila D, Davis RJ, Dawson TM, Dawson VL, Daza P, de Belleroche J, de Figueiredo P, de 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