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Centromeric SMC1 promotes centromer clustering and stabilizes meiotic homolog pairing.

Hatkevich T, Boudreau V, Rubin T, Maddox PS, Huynh JR, Sekelsky J.

PLoS Genet. 2019 Oct 14;15(10):e1008412. doi: 10.1371/journal.pgen.1008412. [Epub ahead of print]


Centromere-Proximal Meiotic Crossovers in Drosophila melanogaster Are Suppressed by Both Highly Repetitive Heterochromatin and Proximity to the Centromere.

Hartmann M, Umbanhowar J, Sekelsky J.

Genetics. 2019 Sep;213(1):113-125. doi: 10.1534/genetics.119.302509. Epub 2019 Jul 25.


Meiotic MCM Proteins Promote and Inhibit Crossovers During Meiotic Recombination.

Hartmann M, Kohl KP, Sekelsky J, Hatkevich T.

Genetics. 2019 Jun;212(2):461-468. doi: 10.1534/genetics.119.302221. Epub 2019 Apr 26.


Local Inversion Heterozygosity Alters Recombination throughout the Genome.

Crown KN, Miller DE, Sekelsky J, Hawley RS.

Curr Biol. 2018 Sep 24;28(18):2984-2990.e3. doi: 10.1016/j.cub.2018.07.004. Epub 2018 Aug 30.


Loss of Drosophila Mei-41/ATR Alters Meiotic Crossover Patterning.

Brady MM, McMahan S, Sekelsky J.

Genetics. 2018 Feb;208(2):579-588. doi: 10.1534/genetics.117.300634. Epub 2017 Dec 15.


Bloom syndrome helicase in meiosis: Pro-crossover functions of an anti-crossover protein.

Hatkevich T, Sekelsky J.

Bioessays. 2017 Sep;39(9). doi: 10.1002/bies.201700073. Epub 2017 Aug 9. Review.


The absence of crossovers on chromosome 4 in Drosophila melanogaster: Imperfection or interesting exception?

Hartmann MA, Sekelsky J.

Fly (Austin). 2017 Oct 2;11(4):253-259. doi: 10.1080/19336934.2017.1321181. Epub 2017 Apr 20. Review.


Substrate preference of Gen endonucleases highlights the importance of branched structures as DNA damage repair intermediates.

Bellendir SP, Rognstad DJ, Morris LP, Zapotoczny G, Walton WG, Redinbo MR, Ramsden DA, Sekelsky J, Erie DA.

Nucleic Acids Res. 2017 May 19;45(9):5333-5348. doi: 10.1093/nar/gkx214.


Annealing of Complementary DNA Sequences During Double-Strand Break Repair in Drosophila Is Mediated by the Ortholog of SMARCAL1.

Holsclaw JK, Sekelsky J.

Genetics. 2017 May;206(1):467-480. doi: 10.1534/genetics.117.200238. Epub 2017 Mar 3.


Human Cell Assays for Synthesis-Dependent Strand Annealing and Crossing over During Double-Strand Break Repair.

Zapotoczny G, Sekelsky J.

G3 (Bethesda). 2017 Apr 3;7(4):1191-1199. doi: 10.1534/g3.116.037390.


DNA Repair in Drosophila: Mutagens, Models, and Missing Genes.

Sekelsky J.

Genetics. 2017 Feb;205(2):471-490. doi: 10.1534/genetics.116.186759. Review.


Bloom Syndrome Helicase Promotes Meiotic Crossover Patterning and Homolog Disjunction.

Hatkevich T, Kohl KP, McMahan S, Hartmann MA, Williams AM, Sekelsky J.

Curr Biol. 2017 Jan 9;27(1):96-102. doi: 10.1016/j.cub.2016.10.055. Epub 2016 Dec 15.


Biochemical Activities and Genetic Functions of the Drosophila melanogaster Fancm Helicase in DNA Repair.

Romero NE, Matson SW, Sekelsky J.

Genetics. 2016 Oct;204(2):531-541. Epub 2016 Jul 27.


Drosophila FANCM helicase prevents spontaneous mitotic crossovers generated by the MUS81 and SLX1 nucleases.

Kuo HK, McMahan S, Rota CM, Kohl KP, Sekelsky J.

Genetics. 2014 Nov;198(3):935-45. doi: 10.1534/genetics.114.168096. Epub 2014 Sep 8.


Eliminating both canonical and short-patch mismatch repair in Drosophila melanogaster suggests a new meiotic recombination model.

Crown KN, McMahan S, Sekelsky J.

PLoS Genet. 2014 Sep 4;10(9):e1004583. doi: 10.1371/journal.pgen.1004583. eCollection 2014 Sep.


Sources and structures of mitotic crossovers that arise when BLM helicase is absent in Drosophila.

LaFave MC, Andersen SL, Stoffregen EP, Holsclaw JK, Kohl KP, Overton LJ, Sekelsky J.

Genetics. 2014 Jan;196(1):107-18. doi: 10.1534/genetics.113.158618. Epub 2013 Oct 30.


An elegans Solution for Crossover Formation.

Bellendir SP, Sekelsky J.

PLoS Genet. 2013;9(7):e1003658. doi: 10.1371/journal.pgen.1003658. Epub 2013 Jul 18. No abstract available.


The development of a monoclonal antibody recognizing the Drosophila melanogaster phosphorylated histone H2A variant (╬│-H2AV).

Lake CM, Holsclaw JK, Bellendir SP, Sekelsky J, Hawley RS.

G3 (Bethesda). 2013 Sep 4;3(9):1539-43. doi: 10.1534/g3.113.006833.


Meiotic and mitotic recombination in meiosis.

Kohl KP, Sekelsky J.

Genetics. 2013 Jun;194(2):327-34. doi: 10.1534/genetics.113.150581. Review.


Targeted gene replacement in Drosophila goes the distance.

Crown KN, Sekelsky J.

Genetics. 2013 Feb;193(2):377-81. doi: 10.1534/genetics.112.148379. No abstract available.


Evolution of an MCM complex in flies that promotes meiotic crossovers by blocking BLM helicase.

Kohl KP, Jones CD, Sekelsky J.

Science. 2012 Dec 7;338(6112):1363-5. doi: 10.1126/science.1228190. Erratum in: Science. 2013 Mar 29;339(6127):1522.


Three structure-selective endonucleases are essential in the absence of BLM helicase in Drosophila.

Andersen SL, Kuo HK, Savukoski D, Brodsky MH, Sekelsky J.

PLoS Genet. 2011 Oct;7(10):e1002315. doi: 10.1371/journal.pgen.1002315. Epub 2011 Oct 13.


Transcription initiation from within P elements generates hypomorphic mutations in Drosophila melanogaster.

LaFave MC, Sekelsky J.

Genetics. 2011 Jul;188(3):749-52. doi: 10.1534/genetics.111.129825. Epub 2011 Apr 28.


Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination.

Andersen SL, Bergstralh DT, Kohl KP, LaRocque JR, Moore CB, Sekelsky J.

Mol Cell. 2009 Jul 10;35(1):128-35. doi: 10.1016/j.molcel.2009.06.019.


DNA damage responses in Drosophila nbs mutants with reduced or altered NBS function.

Mukherjee S, LaFave MC, Sekelsky J.

DNA Repair (Amst). 2009 Jul 4;8(7):803-12. doi: 10.1016/j.dnarep.2009.03.004. Epub 2009 Apr 22.


Mitotic recombination: why? when? how? where?

LaFave MC, Sekelsky J.

PLoS Genet. 2009 Mar;5(3):e1000411. doi: 10.1371/journal.pgen.1000411. Epub 2009 Mar 13. Review. No abstract available.


The 2008 Genetics Society of America Award for Excellence in Education. R. Scott Hawley.

Sekelsky J.

Genetics. 2008 Mar;178(3):1131-3. doi: 10.1534/genetics.104.017835. No abstract available.


Interstrand crosslink repair: can XPF-ERCC1 be let off the hook?

Bergstralh DT, Sekelsky J.

Trends Genet. 2008 Feb;24(2):70-6. doi: 10.1016/j.tig.2007.11.003. Epub 2008 Jan 14. Review.


Synthetic lethality of Drosophila in the absence of the MUS81 endonuclease and the DmBlm helicase is associated with elevated apoptosis.

Trowbridge K, McKim K, Brill SJ, Sekelsky J.

Genetics. 2007 Aug;176(4):1993-2001. Epub 2007 Jul 1.


Multiple functions of Drosophila BLM helicase in maintenance of genome stability.

McVey M, Andersen SL, Broze Y, Sekelsky J.

Genetics. 2007 Aug;176(4):1979-92. Epub 2007 May 16.


Reducing DNA polymerase alpha in the absence of Drosophila ATR leads to P53-dependent apoptosis and developmental defects.

LaRocque JR, Dougherty DL, Hussain SK, Sekelsky J.

Genetics. 2007 Jul;176(3):1441-51. Epub 2007 May 4.


Meiotic recombination in Drosophila Msh6 mutants yields discontinuous gene conversion tracts.

Radford SJ, Sabourin MM, McMahan S, Sekelsky J.

Genetics. 2007 May;176(1):53-62. Epub 2007 Mar 4.


Heteroduplex DNA in meiotic recombination in Drosophila mei-9 mutants.

Radford SJ, McMahan S, Blanton HL, Sekelsky J.

Genetics. 2007 May;176(1):63-72. Epub 2007 Mar 4.


Drosophila ATR in double-strand break repair.

LaRocque JR, Jaklevic B, Su TT, Sekelsky J.

Genetics. 2007 Mar;175(3):1023-33. Epub 2006 Dec 28.


REC, Drosophila MCM8, drives formation of meiotic crossovers.

Blanton HL, Radford SJ, McMahan S, Kearney HM, Ibrahim JG, Sekelsky J.

PLoS Genet. 2005 Sep;1(3):e40.


Drosophila ERCC1 is required for a subset of MEI-9-dependent meiotic crossovers.

Radford SJ, Goley E, Baxter K, McMahan S, Sekelsky J.

Genetics. 2005 Aug;170(4):1737-45. Epub 2005 Jun 8.


Formation of deletions during double-strand break repair in Drosophila DmBlm mutants occurs after strand invasion.

McVey M, Larocque JR, Adams MD, Sekelsky JJ.

Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15694-9. Epub 2004 Oct 22.


Unique invasions and resolutions: DNA repair proteins in meiotic recombination in Drosophila melanogaster.

Blanton H, Sekelsky J.

Cytogenet Genome Res. 2004;107(3-4):172-9. Review.


Evidence for multiple cycles of strand invasion during repair of double-strand gaps in Drosophila.

McVey M, Adams M, Staeva-Vieira E, Sekelsky JJ.

Genetics. 2004 Jun;167(2):699-705.


Mutational analysis of the Drosophila DNA repair and recombination gene mei-9.

Yildiz O, Kearney H, Kramer BC, Sekelsky JJ.

Genetics. 2004 May;167(1):263-73.


Taking Drosophila Rad51 for a SPiN.

Radford SJ, Sekelsky JJ.

Nat Struct Mol Biol. 2004 Jan;11(1):9-10. No abstract available.


Phenotypic analysis of separation-of-function alleles of MEI-41, Drosophila ATM/ATR.

Lauren├žon A, Purdy A, Sekelsky J, Hawley RS, Su TT.

Genetics. 2003 Jun;164(2):589-601.


Drosophila BLM in double-strand break repair by synthesis-dependent strand annealing.

Adams MD, McVey M, Sekelsky JJ.

Science. 2003 Jan 10;299(5604):265-7.


From sequence to phenotype: reverse genetics in Drosophila melanogaster.

Adams MD, Sekelsky JJ.

Nat Rev Genet. 2002 Mar;3(3):189-98. Review.


Biochemical characterization of the small isoform of Drosophila melanogaster RECQ5 helicase.

Ozsoy AZ, Sekelsky JJ, Matson SW.

Nucleic Acids Res. 2001 Jul 15;29(14):2986-93.


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