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Items: 19

1.

Photocaged Quinone Methide Crosslinkers for Light-Controlled Chemical Crosslinking of Protein-Protein and Protein-DNA Complexes.

Liu J, Cai L, Sun W, Cheng R, Wang N, Jin L, Rozovsky S, Seiple IB, Wang L.

Angew Chem Int Ed Engl. 2019 Oct 23. doi: 10.1002/anie.201910135. [Epub ahead of print]

PMID:
31644827
2.

Synthesis, Structural Reassignment, and Antibacterial Evaluation of 2,18-Seco-Lankacidinol B.

Yao Y, Cai L, Seiple IB.

Angew Chem Int Ed Engl. 2018 Oct 8;57(41):13551-13554. doi: 10.1002/anie.201808612. Epub 2018 Sep 11.

3.

Modular, Scalable Synthesis of Group A Streptogramin Antibiotics.

Li Q, Seiple IB.

J Am Chem Soc. 2017 Sep 27;139(38):13304-13307. doi: 10.1021/jacs.7b08577. Epub 2017 Sep 18.

PMID:
28902996
4.

A platform for the discovery of new macrolide antibiotics.

Seiple IB, Zhang Z, Jakubec P, Langlois-Mercier A, Wright PM, Hog DT, Yabu K, Allu SR, Fukuzaki T, Carlsen PN, Kitamura Y, Zhou X, Condakes ML, Szczypiński FT, Green WD, Myers AG.

Nature. 2016 May 19;533(7603):338-45. doi: 10.1038/nature17967.

5.

The evolving role of chemical synthesis in antibacterial drug discovery.

Wright PM, Seiple IB, Myers AG.

Angew Chem Int Ed Engl. 2014 Aug 18;53(34):8840-69. doi: 10.1002/anie.201310843. Epub 2014 Jul 2. Review.

6.

Stereocontrolled synthesis of syn-β-Hydroxy-α-amino acids by direct aldolization of pseudoephenamine glycinamide.

Seiple IB, Mercer JA, Sussman RJ, Zhang Z, Myers AG.

Angew Chem Int Ed Engl. 2014 Apr 25;53(18):4642-7. doi: 10.1002/anie.201400928. Epub 2014 Apr 1.

7.

Palau'amine and related oroidin alkaloids dibromophakellin and dibromophakellstatin inhibit the human 20S proteasome.

Lansdell TA, Hewlett NM, Skoumbourdis AP, Fodor MD, Seiple IB, Su S, Baran PS, Feldman KS, Tepe JJ.

J Nat Prod. 2012 May 25;75(5):980-5. doi: 10.1021/np300231f. Epub 2012 May 16.

8.

Configurational analysis of tetracyclic dimeric pyrrole-imidazole alkaloids using a floating chirality approach.

Köck M, Schmidt G, Seiple IB, Baran PS.

J Nat Prod. 2012 Feb 24;75(2):127-30. doi: 10.1021/np200514g. Epub 2012 Feb 14.

9.

Enantioselective total syntheses of (-)-palau'amine, (-)-axinellamines, and (-)-massadines.

Seiple IB, Su S, Young IS, Nakamura A, Yamaguchi J, Jørgensen L, Rodriguez RA, O'Malley DP, Gaich T, Köck M, Baran PS.

J Am Chem Soc. 2011 Sep 21;133(37):14710-26. doi: 10.1021/ja2047232. Epub 2011 Aug 23.

10.

Innate C-H trifluoromethylation of heterocycles.

Ji Y, Brueckl T, Baxter RD, Fujiwara Y, Seiple IB, Su S, Blackmond DG, Baran PS.

Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14411-5. doi: 10.1073/pnas.1109059108. Epub 2011 Aug 15.

11.

Practical C-H functionalization of quinones with boronic acids.

Fujiwara Y, Domingo V, Seiple IB, Gianatassio R, Del Bel M, Baran PS.

J Am Chem Soc. 2011 Mar 16;133(10):3292-5. doi: 10.1021/ja111152z. Epub 2011 Feb 22.

12.

Direct C-H arylation of electron-deficient heterocycles with arylboronic acids.

Seiple IB, Su S, Rodriguez RA, Gianatassio R, Fujiwara Y, Sobel AL, Baran PS.

J Am Chem Soc. 2010 Sep 29;132(38):13194-6. doi: 10.1021/ja1066459.

13.

Total synthesis of palau'amine.

Seiple IB, Su S, Young IS, Lewis CA, Yamaguchi J, Baran PS.

Angew Chem Int Ed Engl. 2010 Feb 1;49(6):1095-8. doi: 10.1002/anie.200907112. No abstract available.

14.

Total syntheses of (+/-)-massadine and massadine chloride.

Su S, Seiple IB, Young IS, Baran PS.

J Am Chem Soc. 2008 Dec 10;130(49):16490-1. doi: 10.1021/ja8074852. No abstract available.

15.

Total synthesis of (+/-)-axinellamines A and B.

O'Malley DP, Yamaguchi J, Young IS, Seiple IB, Baran PS.

Angew Chem Int Ed Engl. 2008;47(19):3581-3. doi: 10.1002/anie.200801138. No abstract available.

PMID:
18357612
16.

Synthesis of 1,9-dideoxy-pre-axinellamine.

Yamaguchi J, Seiple IB, Young IS, O'Malley DP, Maue M, Baran PS.

Angew Chem Int Ed Engl. 2008;47(19):3578-80. doi: 10.1002/anie.200705913. No abstract available.

PMID:
18357598
17.

The pursuit of palau'amine.

Köck M, Grube A, Seiple IB, Baran PS.

Angew Chem Int Ed Engl. 2007;46(35):6586-94.

PMID:
17724780
18.

Synthesis of taiwaniaquinoids via Nazarov triflation.

Liang G, Xu Y, Seiple IB, Trauner D.

J Am Chem Soc. 2006 Aug 30;128(34):11022-3.

PMID:
16925409
19.

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