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Items: 1 to 50 of 533

1.

Ma'edamines C and D, New Bromotyrosine Alkaloids Possessing a Unique Tetrasubstituted Pyridinium Moiety from an Okinawan Marine Sponge Suberea sp.

Kurimoto SI, Seino S, Fromont J, Kobayashi J, Kubota T.

Org Lett. 2019 Oct 21. doi: 10.1021/acs.orglett.9b03457. [Epub ahead of print]

PMID:
31633367
2.

Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs.

Sanomachi T, Suzuki S, Togashi K, Sugai A, Seino S, Okada M, Yoshioka T, Kitanaka C, Yamamoto M.

Cancers (Basel). 2019 Oct 14;11(10). pii: E1550. doi: 10.3390/cancers11101550.

3.

Topical hyaluronan alone promotes corneal epithelial cell migration whereas combination with benzalkonium chloride impairs epithelial wound healing.

Seino S, Matsuoka R, Masuda Y, Kunou M, Okada Y, Saika S.

Cutan Ocul Toxicol. 2019 Oct 14:1-8. doi: 10.1080/15569527.2019.1673402. [Epub ahead of print]

PMID:
31588814
4.

[Process and outcome evaluation of community-based strategies for frailty prevention in the elderly with the help of the senior workforce at Silver Human Resources Centers in Yabu City, Japan].

Nofuji Y, Seino S, Murayama H, Yoshida Y, Tanigaki T, Yokoyama Y, Narita M, Nishi M, Nakamura M, Kitamura A, Shinkai S.

Nihon Koshu Eisei Zasshi. 2019;66(9):560-573. doi: 10.11236/jph.66.9_560. Japanese.

5.

Brexpiprazole Reduces Survivin and Reverses EGFR Tyrosine Kinase Inhibitor Resistance in Lung and Pancreatic Cancer.

Sanomachi T, Suzuki S, Togashi K, Seino S, Yoshioka T, Kitanaka C, Okada M, Yamamoto M.

Anticancer Res. 2019 Sep;39(9):4817-4828. doi: 10.21873/anticanres.13667.

PMID:
31519584
6.

Reference values of gait parameters measured with a plantar pressure platform in community-dwelling older Japanese adults.

Kawai H, Taniguchi Y, Seino S, Sakurai R, Osuka Y, Obuchi S, Watanabe Y, Kim H, Inagaki H, Kitamura A, Awata S, Shinkai S.

Clin Interv Aging. 2019 Jul 12;14:1265-1276. doi: 10.2147/CIA.S213216. eCollection 2019.

7.

Glucose stimulates somatostatin secretion in pancreatic δ-cells by cAMP-dependent intracellular Ca2+ release.

Denwood G, Tarasov A, Salehi A, Vergari E, Ramracheya R, Takahashi H, Nikolaev VO, Seino S, Gribble F, Reimann F, Rorsman P, Zhang Q.

J Gen Physiol. 2019 Sep 2;151(9):1094-1115. doi: 10.1085/jgp.201912351. Epub 2019 Jul 29.

PMID:
31358556
8.

Albumin and Hemoglobin Trajectories and Incident Disabling Dementia in Community-Dwelling Older Japanese.

Taniguchi Y, Kitamura A, Kaito S, Yokoyama Y, Yokota I, Shinozaki T, Seino S, Murayama H, Matsuyama Y, Ikeuchi T, Fujiwara Y, Shinkai S.

Dement Geriatr Cogn Disord. 2019;47(4-6):233-242. doi: 10.1159/000499837. Epub 2019 Jul 17.

PMID:
31315125
9.

Brexpiprazole, a Serotonin-Dopamine Activity Modulator, Can Sensitize Glioma Stem Cells to Osimertinib, a Third-Generation EGFR-TKI, via Survivin Reduction.

Suzuki S, Yamamoto M, Sanomachi T, Togashi K, Sugai A, Seino S, Yoshioka T, Kitanaka C, Okada M.

Cancers (Basel). 2019 Jul 5;11(7). pii: E947. doi: 10.3390/cancers11070947.

10.

Braving the Element: Pancreatic β-Cell Dysfunction and Adaptation in Response to Arsenic Exposure.

Carmean CM, Seino S.

Front Endocrinol (Lausanne). 2019 Jun 14;10:344. doi: 10.3389/fendo.2019.00344. eCollection 2019. Review.

11.

In vitro and in vivo anti-tumor effects of brexpiprazole, a newly-developed serotonin-dopamine activity modulator with an improved safety profile.

Suzuki S, Yamamoto M, Togashi K, Sanomachi T, Sugai A, Seino S, Yoshioka T, Kitanaka C, Okada M.

Oncotarget. 2019 May 28;10(37):3547-3558. doi: 10.18632/oncotarget.26949. eCollection 2019 May 28.

12.

Glutamate as intracellular and extracellular signals in pancreatic islet functions.

Takahashi H, Yokoi N, Seino S.

Proc Jpn Acad Ser B Phys Biol Sci. 2019;95(6):246-260. doi: 10.2183/pjab.95.017.

13.

Pathway from gait speed to incidence of disability and mortality in older adults: A mediating role of physical activity.

Abe T, Kitamura A, Taniguchi Y, Amano H, Seino S, Yokoyama Y, Nishi M, Narita M, Ikeuchi T, Fujiwara Y, Shinkai S.

Maturitas. 2019 May;123:32-36. doi: 10.1016/j.maturitas.2019.02.002. Epub 2019 Feb 7.

PMID:
31027674
14.

Correction: Physical, social, and psychological characteristics of community-dwelling elderly Japanese dog and cat owners.

Taniguchi Y, Seino S, Nishi M, Tomine Y, Tanaka I, Yokoyama Y, Amano H, Kitamura A, Shinkai S.

PLoS One. 2019 Mar 28;14(3):e0214824. doi: 10.1371/journal.pone.0214824. eCollection 2019.

15.

Characteristics for gait parameters of community-dwelling elderly Japanese with lower cognitive function.

Taniguchi Y, Watanabe Y, Osuka Y, Kitamura A, Seino S, Kim H, Kawai H, Sakurai R, Inagaki H, Awata S, Shinkai S.

PLoS One. 2019 Mar 27;14(3):e0212646. doi: 10.1371/journal.pone.0212646. eCollection 2019.

16.

Improved Catalytic Durability of Pt-Particle/ABS for H₂O₂ Decomposition in Contact Lens Cleaning.

Ohkubo Y, Aoki T, Seino S, Mori O, Ito I, Endo K, Yamamura K.

Nanomaterials (Basel). 2019 Mar 3;9(3). pii: E342. doi: 10.3390/nano9030342.

17.

Combined effect of diabetes and frailty on mortality and incident disability in older Japanese adults.

Kitamura A, Taniguchi Y, Seino S, Yokoyama Y, Amano H, Fujiwara Y, Shinkai S.

Geriatr Gerontol Int. 2019 May;19(5):423-428. doi: 10.1111/ggi.13637. Epub 2019 Feb 20.

PMID:
30788903
18.

AS602801 Sensitizes Ovarian Cancer Stem Cells to Paclitaxel by Down-regulating MDR1.

Yamamoto M, Suzuki S, Togashi K, Sanomachi T, Seino S, Kitanaka C, Okada M.

Anticancer Res. 2019 Feb;39(2):609-617. doi: 10.21873/anticanres.13154.

PMID:
30711936
19.

Exercise Arrangement Is Associated with Physical and Mental Health in Older Adults.

Seino S, Kitamura A, Tomine Y, Tanaka I, Nishi M, Taniguchi YU, Yokoyama Y, Amano H, Fujiwara Y, Shinkai S.

Med Sci Sports Exerc. 2019 Jun;51(6):1146-1153. doi: 10.1249/MSS.0000000000001884.

20.

Early injection of human adipose tissue-derived mesenchymal stem cell after inflammation ameliorates dextran sulfate sodium-induced colitis in mice through the induction of M2 macrophages and regulatory T cells.

Kawata Y, Tsuchiya A, Seino S, Watanabe Y, Kojima Y, Ikarashi S, Tominaga K, Yokoyama J, Yamagiwa S, Terai S.

Cell Tissue Res. 2019 May;376(2):257-271. doi: 10.1007/s00441-018-02981-w. Epub 2019 Jan 11.

PMID:
30635774
21.

[Relationship between eating alone and dietary variety among urban older Japanese adults].

Tanaka I, Kitamura A, Seino S, Nishi M, Tomine Y, Taniguchi Y, Yokoyama Y, Narita M, Shinkai S.

Nihon Koshu Eisei Zasshi. 2018;65(12):744-754. doi: 10.11236/jph.65.12_744. Japanese.

22.

A Rare Duodenal Carcinosarcoma: A Case Report and Literature Review.

Arao Y, Kamimura K, Ikemi M, Takaki M, Takahashi S, Seino S, Abe H, Kohisa J, Kato T, Ajioka Y, Terai S.

Intern Med. 2019 May 1;58(9):1273-1278. doi: 10.2169/internalmedicine.2094-18. Epub 2018 Dec 18. Review.

23.

Arsenic modifies serotonin metabolism through glucuronidation in pancreatic β-cells

Carmean CM, Yokoi N, Takahashi H, Oduori OS, Kang C, Kanagawa A, Kirkley AG, Han G, Landeche M, Hidaka S, Katoh M, Sargis RM, Seino S.

Am J Physiol Endocrinol Metab. 2019 Mar 1;316(3):E464-E474. doi: 10.1152/ajpendo.00302.2018. Epub 2018 Dec 18.

PMID:
30562058
24.

AS602801, an Anticancer Stem Cell Candidate Drug, Reduces Survivin Expression and Sensitizes A2780 Ovarian Cancer Stem Cells to Carboplatin and Paclitaxel.

Yamamoto M, Suzuki S, Togashi K, Sanomachi T, Seino S, Kitanaka C, Okada M.

Anticancer Res. 2018 Dec;38(12):6699-6706. doi: 10.21873/anticanres.13038.

PMID:
30504379
25.

Frequency of Balanced-Meal Consumption and Frailty in Community-Dwelling Older Japanese: A Cross-Sectional Study.

Yokoyama Y, Kitamura A, Nishi M, Seino S, Taniguchi Y, Amano H, Ikeuchi T, Shinkai S.

J Epidemiol. 2019 Oct 5;29(10):370-376. doi: 10.2188/jea.JE20180076. Epub 2018 Nov 17.

26.

Physical, social, and psychological characteristics of community-dwelling elderly Japanese dog and cat owners.

Taniguchi Y, Seino S, Nishi M, Tomine Y, Tanaka I, Yokoyama Y, Amano H, Kitamura A, Shinkai S.

PLoS One. 2018 Nov 14;13(11):e0206399. doi: 10.1371/journal.pone.0206399. eCollection 2018. Erratum in: PLoS One. 2019 Mar 28;14(3):e0214824.

27.

Prevalence of frailty, cognitive impairment, and sarcopenia in outpatients with cardiometabolic disease in a frailty clinic.

Tamura Y, Ishikawa J, Fujiwara Y, Tanaka M, Kanazawa N, Chiba Y, Iizuka A, Kaito S, Tanaka J, Sugie M, Nishimura T, Kanemaru A, Shimoji K, Hirano H, Furuta K, Kitamura A, Seino S, Shinkai S, Harada K, Kyo S, Ito H, Araki A.

BMC Geriatr. 2018 Nov 6;18(1):264. doi: 10.1186/s12877-018-0955-4.

28.

Mesenchymal Stem Cells and Induced Bone Marrow-Derived Macrophages Synergistically Improve Liver Fibrosis in Mice.

Watanabe Y, Tsuchiya A, Seino S, Kawata Y, Kojima Y, Ikarashi S, Starkey Lewis PJ, Lu WY, Kikuta J, Kawai H, Yamagiwa S, Forbes SJ, Ishii M, Terai S.

Stem Cells Transl Med. 2019 Mar;8(3):271-284. doi: 10.1002/sctm.18-0105. Epub 2018 Nov 5.

29.

Involvement of GLUT1-mediated glucose transport and metabolism in gefitinib resistance of non-small-cell lung cancer cells.

Suzuki S, Okada M, Takeda H, Kuramoto K, Sanomachi T, Togashi K, Seino S, Yamamoto M, Yoshioka T, Kitanaka C.

Oncotarget. 2018 Aug 24;9(66):32667-32679. doi: 10.18632/oncotarget.25994. eCollection 2018 Aug 24.

30.

Impaired glucagon secretion in patients with fulminant type 1 diabetes mellitus.

Komada H, Hirota Y, Sakaguchi K, Okuno Y, Ogawa W, Seino S.

Endocrine. 2019 Mar;63(3):476-479. doi: 10.1007/s12020-018-1750-x. Epub 2018 Sep 10.

PMID:
30203124
31.

AS602801, an Anti-Cancer Stem Cell Drug Candidate, Suppresses Gap-junction Communication Between Lung Cancer Stem Cells and Astrocytes.

Kuramoto K, Yamamoto M, Suzuki S, Sanomachi T, Togashi K, Seino S, Kitanaka C, Okada M.

Anticancer Res. 2018 Sep;38(9):5093-5099. doi: 10.21873/anticanres.12829.

PMID:
30194154
32.

Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of KATP Channel Blockers.

Lai BK, Chae H, Gómez-Ruiz A, Cheng P, Gallo P, Antoine N, Beauloye C, Jonas JC, Seghers V, Seino S, Gilon P.

Diabetes. 2018 Nov;67(11):2239-2253. doi: 10.2337/db17-0880. Epub 2018 Aug 16.

33.

Development of the Nutrition and Functionality Assessment (NFA) among Older Adults in Japan.

Okubo Y, Nemoto M, Osuka Y, Jung S, Seino S, Figueroa R, Vinyes-Pares G, Offord EA, Shevlyakova M, Breuille D, Tanaka K.

J Frailty Aging. 2018;7(3):187-192. doi: 10.14283/jfa.2017.38.

PMID:
30095150
34.

Low Body Mass Index is a Poor Prognosis Factor in Cardioembolic Stroke Patients with NonValvular Atrial Fibrillation.

Hagii J, Metoki N, Saito S, Fujita A, Shiroto H, Sasaki S, Takahashi K, Hitomi H, Baba Y, Seino S, Kamada T, Uchizawa T, Iwata M, Matsumoto S, Yasujima M, Tomita H.

J Stroke Cerebrovasc Dis. 2018 Nov;27(11):3155-3162. doi: 10.1016/j.jstrokecerebrovasdis.2018.07.002. Epub 2018 Aug 6.

PMID:
30093200
35.

Functional adenosine triphosphate-sensitive potassium channel is required in high-carbohydrate diet-induced increase in β-cell mass.

Murase M, Seino Y, Maekawa R, Iida A, Hosokawa K, Hayami T, Tsunekawa S, Hamada Y, Yokoi N, Seino S, Hayashi Y, Arima H.

J Diabetes Investig. 2019 Mar;10(2):238-250. doi: 10.1111/jdi.12907. Epub 2018 Sep 4.

36.

Ectopic overexpression of Kir6.1 in the mouse heart impacts on the life expectancy.

Watanabe Y, Kishimoto T, Miki T, Seino S, Nakaya H, Matsumoto A.

Sci Rep. 2018 Aug 6;8(1):11723. doi: 10.1038/s41598-018-30175-5.

37.

A Small-molecule Kinase Inhibitor, CEP-1347, Inhibits Survivin Expression and Sensitizes Ovarian Cancer Stem Cells to Paclitaxel.

Togashi K, Okada M, Yamamoto M, Suzuki S, Sanomachi T, Seino S, Yamashita H, Kitanaka C.

Anticancer Res. 2018 Aug;38(8):4535-4542. doi: 10.21873/anticanres.12757.

PMID:
30061219
38.

Activation of GLP-1 receptor signalling alleviates cellular stresses and improves beta cell function in a mouse model of Wolfram syndrome.

Kondo M, Tanabe K, Amo-Shiinoki K, Hatanaka M, Morii T, Takahashi H, Seino S, Yamada Y, Tanizawa Y.

Diabetologia. 2018 Oct;61(10):2189-2201. doi: 10.1007/s00125-018-4679-y. Epub 2018 Jul 28.

PMID:
30054673
39.

A Community-Wide Intervention Trial for Preventing and Reducing Frailty Among Older Adults Living in Metropolitan Areas: Design and Baseline Survey for a Study Integrating Participatory Action Research With a Cluster Trial.

Seino S, Kitamura A, Tomine Y, Tanaka I, Nishi M, Nonaka K, Nofuji Y, Narita M, Taniguchi Y, Yokoyama Y, Amano H, Ikeuchi T, Fujiwara Y, Shinkai S.

J Epidemiol. 2019 Feb 5;29(2):73-81. doi: 10.2188/jea.JE20170109. Epub 2018 Jun 30.

40.

Inhibition of SNAT5 Induces Incretin-Responsive State From Incretin-Unresponsive State in Pancreatic β-Cells: Study of β-Cell Spheroid Clusters as a Model.

Hashim M, Yokoi N, Takahashi H, Gheni G, Okechi OS, Hayami T, Murao N, Hidaka S, Minami K, Mizoguchi A, Seino S.

Diabetes. 2018 Sep;67(9):1795-1806. doi: 10.2337/db17-1486. Epub 2018 Jun 28.

41.

Gnetin C, a resveratrol dimer, reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ42-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.

Seino S, Kimoto T, Yoshida H, Tanji K, Matsumiya T, Hayakari R, Seya K, Kawaguchi S, Tsuruga K, Tanaka H, Imaizumi T.

Biomed Res. 2018;39(3):105-115. doi: 10.2220/biomedres.39.105.

42.

Individual- and community-level neighbor relationships and physical activity among older Japanese adults living in a metropolitan area: a cross-sectional multilevel analysis.

Seino S, Kitamura A, Nishi M, Tomine Y, Tanaka I, Taniguchi Y, Yokoyama Y, Amano H, Narita M, Ikeuchi T, Fujiwara Y, Shinkai S.

Int J Behav Nutr Phys Act. 2018 May 25;15(1):46. doi: 10.1186/s12966-018-0679-z.

43.

Clinical outcome of hepatocellular carcinoma can be predicted by the expression of hepatic progenitor cell markers and serum tumour markers.

Seino S, Tsuchiya A, Watanabe Y, Kawata Y, Kojima Y, Ikarashi S, Yanai H, Nakamura K, Kumaki D, Hirano M, Funakoshi K, Aono T, Sakai T, Sakata J, Takamura M, Kawai H, Yamagiwa S, Wakai T, Terai S.

Oncotarget. 2018 Apr 24;9(31):21844-21860. doi: 10.18632/oncotarget.25074. eCollection 2018 Apr 24.

44.

Spontaneous Micro-Aggregation of Platelets Predicts Clinical Outcome in Acute Ischemic Stroke.

Kudoh R, Mikami K, Kitajima M, Aizu K, Kitajima Y, Hagii J, Metoki H, Seino S, Baba Y, Yasujima M, Osanai T.

J Stroke Cerebrovasc Dis. 2018 Aug;27(8):2074-2081. doi: 10.1016/j.jstrokecerebrovasdis.2018.03.004. Epub 2018 Apr 4.

PMID:
29627170
45.

Trajectories of arterial stiffness and all-cause mortality among community-dwelling older Japanese.

Taniguchi Y, Kitamura A, Shinozaki T, Seino S, Yokoyama Y, Narita M, Amano H, Matsuyama Y, Fujiwara Y, Shinkai S.

Geriatr Gerontol Int. 2018 Jul;18(7):1108-1113. doi: 10.1111/ggi.13323. Epub 2018 Apr 2.

PMID:
29608041
46.

Association of Trajectories of Higher-Level Functional Capacity with Mortality and Medical and Long-Term Care Costs Among Community-Dwelling Older Japanese.

Taniguchi Y, Kitamura A, Nofuji Y, Ishizaki T, Seino S, Yokoyama Y, Shinozaki T, Murayama H, Mitsutake S, Amano H, Nishi M, Matsuyama Y, Fujiwara Y, Shinkai S.

J Gerontol A Biol Sci Med Sci. 2019 Jan 16;74(2):211-218. doi: 10.1093/gerona/gly024.

PMID:
29596617
47.

Characteristics of repaglinide effects on insulin secretion.

Takahashi H, Hidaka S, Seki C, Yokoi N, Seino S.

Eur J Pharmacol. 2018 Jun 5;828:52-59. doi: 10.1016/j.ejphar.2018.03.025. Epub 2018 Mar 16.

PMID:
29555503
48.

Nasalization by Nasalis larvatus: Larger noses audiovisually advertise conspecifics in proboscis monkeys.

Koda H, Murai T, Tuuga A, Goossens B, Nathan SKSS, Stark DJ, Ramirez DAR, Sha JCM, Osman I, Sipangkui R, Seino S, Matsuda I.

Sci Adv. 2018 Feb 21;4(2):eaaq0250. doi: 10.1126/sciadv.aaq0250. eCollection 2018 Feb.

49.

Comparison of Stabilizer Effects on the Size, Dispersion, and Catalytic Property of Pt, PtCu, and PtRu Nanoparticles.

Kugai J, Seino S, Nakagawa T, Yamamoto TA, Tanaka S, Taguchi N.

J Nanosci Nanotechnol. 2018 Aug 1;18(8):5738-5748. doi: 10.1166/jnn.2018.15437.

PMID:
29458634
50.

Fecal Nutrients Suggest Diets of Higher Fiber Levels in Free-Ranging than in Captive Proboscis Monkeys (Nasalis larvatus).

Matsuda I, Bernard H, Tuuga A, Nathan SKSS, Sha JCM, Osman I, Sipangkui R, Seino S, Asano S, Wong A, Kreuzer M, Ramirez Saldivar DA, Clauss M.

Front Vet Sci. 2018 Jan 19;4:246. doi: 10.3389/fvets.2017.00246. eCollection 2017.

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