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Items: 1 to 50 of 526

1.

Albumin and Hemoglobin Trajectories and Incident Disabling Dementia in Community-Dwelling Older Japanese.

Taniguchi Y, Kitamura A, Kaito S, Yokoyama Y, Yokota I, Shinozaki T, Seino S, Murayama H, Matsuyama Y, Ikeuchi T, Fujiwara Y, Shinkai S.

Dement Geriatr Cogn Disord. 2019 Jul 17:1-10. doi: 10.1159/000499837. [Epub ahead of print]

PMID:
31315125
2.

Brexpiprazole, a Serotonin-Dopamine Activity Modulator, Can Sensitize Glioma Stem Cells to Osimertinib, a Third-Generation EGFR-TKI, via Survivin Reduction.

Suzuki S, Yamamoto M, Sanomachi T, Togashi K, Sugai A, Seino S, Yoshioka T, Kitanaka C, Okada M.

Cancers (Basel). 2019 Jul 5;11(7). pii: E947. doi: 10.3390/cancers11070947.

3.

Braving the Element: Pancreatic β-Cell Dysfunction and Adaptation in Response to Arsenic Exposure.

Carmean CM, Seino S.

Front Endocrinol (Lausanne). 2019 Jun 14;10:344. doi: 10.3389/fendo.2019.00344. eCollection 2019. Review.

4.

In vitro and in vivo anti-tumor effects of brexpiprazole, a newly-developed serotonin-dopamine activity modulator with an improved safety profile.

Suzuki S, Yamamoto M, Togashi K, Sanomachi T, Sugai A, Seino S, Yoshioka T, Kitanaka C, Okada M.

Oncotarget. 2019 May 28;10(37):3547-3558. doi: 10.18632/oncotarget.26949. eCollection 2019 May 28.

5.

Glutamate as intracellular and extracellular signals in pancreatic islet functions.

Takahashi H, Yokoi N, Seino S.

Proc Jpn Acad Ser B Phys Biol Sci. 2019;95(6):246-260. doi: 10.2183/pjab.95.017.

6.

Pathway from gait speed to incidence of disability and mortality in older adults: A mediating role of physical activity.

Abe T, Kitamura A, Taniguchi Y, Amano H, Seino S, Yokoyama Y, Nishi M, Narita M, Ikeuchi T, Fujiwara Y, Shinkai S.

Maturitas. 2019 May;123:32-36. doi: 10.1016/j.maturitas.2019.02.002. Epub 2019 Feb 7.

PMID:
31027674
7.

Correction: Physical, social, and psychological characteristics of community-dwelling elderly Japanese dog and cat owners.

Taniguchi Y, Seino S, Nishi M, Tomine Y, Tanaka I, Yokoyama Y, Amano H, Kitamura A, Shinkai S.

PLoS One. 2019 Mar 28;14(3):e0214824. doi: 10.1371/journal.pone.0214824. eCollection 2019.

8.

Characteristics for gait parameters of community-dwelling elderly Japanese with lower cognitive function.

Taniguchi Y, Watanabe Y, Osuka Y, Kitamura A, Seino S, Kim H, Kawai H, Sakurai R, Inagaki H, Awata S, Shinkai S.

PLoS One. 2019 Mar 27;14(3):e0212646. doi: 10.1371/journal.pone.0212646. eCollection 2019.

9.

Improved Catalytic Durability of Pt-Particle/ABS for H₂O₂ Decomposition in Contact Lens Cleaning.

Ohkubo Y, Aoki T, Seino S, Mori O, Ito I, Endo K, Yamamura K.

Nanomaterials (Basel). 2019 Mar 3;9(3). pii: E342. doi: 10.3390/nano9030342.

10.

Combined effect of diabetes and frailty on mortality and incident disability in older Japanese adults.

Kitamura A, Taniguchi Y, Seino S, Yokoyama Y, Amano H, Fujiwara Y, Shinkai S.

Geriatr Gerontol Int. 2019 May;19(5):423-428. doi: 10.1111/ggi.13637. Epub 2019 Feb 20.

PMID:
30788903
11.

AS602801 Sensitizes Ovarian Cancer Stem Cells to Paclitaxel by Down-regulating MDR1.

Yamamoto M, Suzuki S, Togashi K, Sanomachi T, Seino S, Kitanaka C, Okada M.

Anticancer Res. 2019 Feb;39(2):609-617. doi: 10.21873/anticanres.13154.

PMID:
30711936
12.

Exercise Arrangement Is Associated with Physical and Mental Health in Older Adults.

Seino S, Kitamura A, Tomine Y, Tanaka I, Nishi M, Taniguchi YU, Yokoyama Y, Amano H, Fujiwara Y, Shinkai S.

Med Sci Sports Exerc. 2019 Jun;51(6):1146-1153. doi: 10.1249/MSS.0000000000001884.

PMID:
30694973
13.

Early injection of human adipose tissue-derived mesenchymal stem cell after inflammation ameliorates dextran sulfate sodium-induced colitis in mice through the induction of M2 macrophages and regulatory T cells.

Kawata Y, Tsuchiya A, Seino S, Watanabe Y, Kojima Y, Ikarashi S, Tominaga K, Yokoyama J, Yamagiwa S, Terai S.

Cell Tissue Res. 2019 May;376(2):257-271. doi: 10.1007/s00441-018-02981-w. Epub 2019 Jan 11.

PMID:
30635774
14.

[Relationship between eating alone and dietary variety among urban older Japanese adults].

Tanaka I, Kitamura A, Seino S, Nishi M, Tomine Y, Taniguchi Y, Yokoyama Y, Narita M, Shinkai S.

Nihon Koshu Eisei Zasshi. 2018;65(12):744-754. doi: 10.11236/jph.65.12_744. Japanese.

15.

A Rare Duodenal Carcinosarcoma: A Case Report and Literature Review.

Arao Y, Kamimura K, Ikemi M, Takaki M, Takahashi S, Seino S, Abe H, Kohisa J, Kato T, Ajioka Y, Terai S.

Intern Med. 2019 May 1;58(9):1273-1278. doi: 10.2169/internalmedicine.2094-18. Epub 2018 Dec 18. Review.

16.

Arsenic modifies serotonin metabolism through glucuronidation in pancreatic β-cells

Carmean CM, Yokoi N, Takahashi H, Oduori OS, Kang C, Kanagawa A, Kirkley AG, Han G, Landeche M, Hidaka S, Katoh M, Sargis RM, Seino S.

Am J Physiol Endocrinol Metab. 2019 Mar 1;316(3):E464-E474. doi: 10.1152/ajpendo.00302.2018. Epub 2018 Dec 18.

PMID:
30562058
17.

AS602801, an Anticancer Stem Cell Candidate Drug, Reduces Survivin Expression and Sensitizes A2780 Ovarian Cancer Stem Cells to Carboplatin and Paclitaxel.

Yamamoto M, Suzuki S, Togashi K, Sanomachi T, Seino S, Kitanaka C, Okada M.

Anticancer Res. 2018 Dec;38(12):6699-6706. doi: 10.21873/anticanres.13038.

PMID:
30504379
18.

Frequency of Balanced-Meal Consumption and Frailty in Community-Dwelling Older Japanese: A Cross-Sectional Study.

Yokoyama Y, Kitamura A, Nishi M, Seino S, Taniguchi Y, Amano H, Ikeuchi T, Shinkai S.

J Epidemiol. 2018 Nov 17. doi: 10.2188/jea.JE20180076. [Epub ahead of print]

19.

Physical, social, and psychological characteristics of community-dwelling elderly Japanese dog and cat owners.

Taniguchi Y, Seino S, Nishi M, Tomine Y, Tanaka I, Yokoyama Y, Amano H, Kitamura A, Shinkai S.

PLoS One. 2018 Nov 14;13(11):e0206399. doi: 10.1371/journal.pone.0206399. eCollection 2018. Erratum in: PLoS One. 2019 Mar 28;14(3):e0214824.

20.

Prevalence of frailty, cognitive impairment, and sarcopenia in outpatients with cardiometabolic disease in a frailty clinic.

Tamura Y, Ishikawa J, Fujiwara Y, Tanaka M, Kanazawa N, Chiba Y, Iizuka A, Kaito S, Tanaka J, Sugie M, Nishimura T, Kanemaru A, Shimoji K, Hirano H, Furuta K, Kitamura A, Seino S, Shinkai S, Harada K, Kyo S, Ito H, Araki A.

BMC Geriatr. 2018 Nov 6;18(1):264. doi: 10.1186/s12877-018-0955-4.

21.

Mesenchymal Stem Cells and Induced Bone Marrow-Derived Macrophages Synergistically Improve Liver Fibrosis in Mice.

Watanabe Y, Tsuchiya A, Seino S, Kawata Y, Kojima Y, Ikarashi S, Starkey Lewis PJ, Lu WY, Kikuta J, Kawai H, Yamagiwa S, Forbes SJ, Ishii M, Terai S.

Stem Cells Transl Med. 2019 Mar;8(3):271-284. doi: 10.1002/sctm.18-0105. Epub 2018 Nov 5.

22.

Involvement of GLUT1-mediated glucose transport and metabolism in gefitinib resistance of non-small-cell lung cancer cells.

Suzuki S, Okada M, Takeda H, Kuramoto K, Sanomachi T, Togashi K, Seino S, Yamamoto M, Yoshioka T, Kitanaka C.

Oncotarget. 2018 Aug 24;9(66):32667-32679. doi: 10.18632/oncotarget.25994. eCollection 2018 Aug 24.

23.

Impaired glucagon secretion in patients with fulminant type 1 diabetes mellitus.

Komada H, Hirota Y, Sakaguchi K, Okuno Y, Ogawa W, Seino S.

Endocrine. 2019 Mar;63(3):476-479. doi: 10.1007/s12020-018-1750-x. Epub 2018 Sep 10.

PMID:
30203124
24.

AS602801, an Anti-Cancer Stem Cell Drug Candidate, Suppresses Gap-junction Communication Between Lung Cancer Stem Cells and Astrocytes.

Kuramoto K, Yamamoto M, Suzuki S, Sanomachi T, Togashi K, Seino S, Kitanaka C, Okada M.

Anticancer Res. 2018 Sep;38(9):5093-5099. doi: 10.21873/anticanres.12829.

PMID:
30194154
25.

Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of KATP Channel Blockers.

Lai BK, Chae H, Gómez-Ruiz A, Cheng P, Gallo P, Antoine N, Beauloye C, Jonas JC, Seghers V, Seino S, Gilon P.

Diabetes. 2018 Nov;67(11):2239-2253. doi: 10.2337/db17-0880. Epub 2018 Aug 16.

26.

Development of the Nutrition and Functionality Assessment (NFA) among Older Adults in Japan.

Okubo Y, Nemoto M, Osuka Y, Jung S, Seino S, Figueroa R, Vinyes-Pares G, Offord EA, Shevlyakova M, Breuille D, Tanaka K.

J Frailty Aging. 2018;7(3):187-192. doi: 10.14283/jfa.2017.38.

PMID:
30095150
27.

Low Body Mass Index is a Poor Prognosis Factor in Cardioembolic Stroke Patients with NonValvular Atrial Fibrillation.

Hagii J, Metoki N, Saito S, Fujita A, Shiroto H, Sasaki S, Takahashi K, Hitomi H, Baba Y, Seino S, Kamada T, Uchizawa T, Iwata M, Matsumoto S, Yasujima M, Tomita H.

J Stroke Cerebrovasc Dis. 2018 Nov;27(11):3155-3162. doi: 10.1016/j.jstrokecerebrovasdis.2018.07.002. Epub 2018 Aug 6.

PMID:
30093200
28.

Functional adenosine triphosphate-sensitive potassium channel is required in high-carbohydrate diet-induced increase in β-cell mass.

Murase M, Seino Y, Maekawa R, Iida A, Hosokawa K, Hayami T, Tsunekawa S, Hamada Y, Yokoi N, Seino S, Hayashi Y, Arima H.

J Diabetes Investig. 2019 Mar;10(2):238-250. doi: 10.1111/jdi.12907. Epub 2018 Sep 4.

29.

Ectopic overexpression of Kir6.1 in the mouse heart impacts on the life expectancy.

Watanabe Y, Kishimoto T, Miki T, Seino S, Nakaya H, Matsumoto A.

Sci Rep. 2018 Aug 6;8(1):11723. doi: 10.1038/s41598-018-30175-5.

30.

A Small-molecule Kinase Inhibitor, CEP-1347, Inhibits Survivin Expression and Sensitizes Ovarian Cancer Stem Cells to Paclitaxel.

Togashi K, Okada M, Yamamoto M, Suzuki S, Sanomachi T, Seino S, Yamashita H, Kitanaka C.

Anticancer Res. 2018 Aug;38(8):4535-4542. doi: 10.21873/anticanres.12757.

PMID:
30061219
31.

Activation of GLP-1 receptor signalling alleviates cellular stresses and improves beta cell function in a mouse model of Wolfram syndrome.

Kondo M, Tanabe K, Amo-Shiinoki K, Hatanaka M, Morii T, Takahashi H, Seino S, Yamada Y, Tanizawa Y.

Diabetologia. 2018 Oct;61(10):2189-2201. doi: 10.1007/s00125-018-4679-y. Epub 2018 Jul 28.

PMID:
30054673
32.

A Community-Wide Intervention Trial for Preventing and Reducing Frailty Among Older Adults Living in Metropolitan Areas: Design and Baseline Survey for a Study Integrating Participatory Action Research With a Cluster Trial.

Seino S, Kitamura A, Tomine Y, Tanaka I, Nishi M, Nonaka K, Nofuji Y, Narita M, Taniguchi Y, Yokoyama Y, Amano H, Ikeuchi T, Fujiwara Y, Shinkai S.

J Epidemiol. 2019 Feb 5;29(2):73-81. doi: 10.2188/jea.JE20170109. Epub 2018 Jun 30.

33.

Inhibition of SNAT5 Induces Incretin-Responsive State From Incretin-Unresponsive State in Pancreatic β-Cells: Study of β-Cell Spheroid Clusters as a Model.

Hashim M, Yokoi N, Takahashi H, Gheni G, Okechi OS, Hayami T, Murao N, Hidaka S, Minami K, Mizoguchi A, Seino S.

Diabetes. 2018 Sep;67(9):1795-1806. doi: 10.2337/db17-1486. Epub 2018 Jun 28.

34.

Gnetin C, a resveratrol dimer, reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ42-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.

Seino S, Kimoto T, Yoshida H, Tanji K, Matsumiya T, Hayakari R, Seya K, Kawaguchi S, Tsuruga K, Tanaka H, Imaizumi T.

Biomed Res. 2018;39(3):105-115. doi: 10.2220/biomedres.39.105.

35.

Individual- and community-level neighbor relationships and physical activity among older Japanese adults living in a metropolitan area: a cross-sectional multilevel analysis.

Seino S, Kitamura A, Nishi M, Tomine Y, Tanaka I, Taniguchi Y, Yokoyama Y, Amano H, Narita M, Ikeuchi T, Fujiwara Y, Shinkai S.

Int J Behav Nutr Phys Act. 2018 May 25;15(1):46. doi: 10.1186/s12966-018-0679-z.

36.

Clinical outcome of hepatocellular carcinoma can be predicted by the expression of hepatic progenitor cell markers and serum tumour markers.

Seino S, Tsuchiya A, Watanabe Y, Kawata Y, Kojima Y, Ikarashi S, Yanai H, Nakamura K, Kumaki D, Hirano M, Funakoshi K, Aono T, Sakai T, Sakata J, Takamura M, Kawai H, Yamagiwa S, Wakai T, Terai S.

Oncotarget. 2018 Apr 24;9(31):21844-21860. doi: 10.18632/oncotarget.25074. eCollection 2018 Apr 24.

37.

Spontaneous Micro-Aggregation of Platelets Predicts Clinical Outcome in Acute Ischemic Stroke.

Kudoh R, Mikami K, Kitajima M, Aizu K, Kitajima Y, Hagii J, Metoki H, Seino S, Baba Y, Yasujima M, Osanai T.

J Stroke Cerebrovasc Dis. 2018 Aug;27(8):2074-2081. doi: 10.1016/j.jstrokecerebrovasdis.2018.03.004. Epub 2018 Apr 4.

PMID:
29627170
38.

Trajectories of arterial stiffness and all-cause mortality among community-dwelling older Japanese.

Taniguchi Y, Kitamura A, Shinozaki T, Seino S, Yokoyama Y, Narita M, Amano H, Matsuyama Y, Fujiwara Y, Shinkai S.

Geriatr Gerontol Int. 2018 Jul;18(7):1108-1113. doi: 10.1111/ggi.13323. Epub 2018 Apr 2.

PMID:
29608041
39.

Association of Trajectories of Higher-Level Functional Capacity with Mortality and Medical and Long-Term Care Costs Among Community-Dwelling Older Japanese.

Taniguchi Y, Kitamura A, Nofuji Y, Ishizaki T, Seino S, Yokoyama Y, Shinozaki T, Murayama H, Mitsutake S, Amano H, Nishi M, Matsuyama Y, Fujiwara Y, Shinkai S.

J Gerontol A Biol Sci Med Sci. 2019 Jan 16;74(2):211-218. doi: 10.1093/gerona/gly024.

PMID:
29596617
40.

Characteristics of repaglinide effects on insulin secretion.

Takahashi H, Hidaka S, Seki C, Yokoi N, Seino S.

Eur J Pharmacol. 2018 Jun 5;828:52-59. doi: 10.1016/j.ejphar.2018.03.025. Epub 2018 Mar 16.

PMID:
29555503
41.

Nasalization by Nasalis larvatus: Larger noses audiovisually advertise conspecifics in proboscis monkeys.

Koda H, Murai T, Tuuga A, Goossens B, Nathan SKSS, Stark DJ, Ramirez DAR, Sha JCM, Osman I, Sipangkui R, Seino S, Matsuda I.

Sci Adv. 2018 Feb 21;4(2):eaaq0250. doi: 10.1126/sciadv.aaq0250. eCollection 2018 Feb.

42.

Comparison of Stabilizer Effects on the Size, Dispersion, and Catalytic Property of Pt, PtCu, and PtRu Nanoparticles.

Kugai J, Seino S, Nakagawa T, Yamamoto TA, Tanaka S, Taguchi N.

J Nanosci Nanotechnol. 2018 Aug 1;18(8):5738-5748. doi: 10.1166/jnn.2018.15437.

PMID:
29458634
43.

Fecal Nutrients Suggest Diets of Higher Fiber Levels in Free-Ranging than in Captive Proboscis Monkeys (Nasalis larvatus).

Matsuda I, Bernard H, Tuuga A, Nathan SKSS, Sha JCM, Osman I, Sipangkui R, Seino S, Asano S, Wong A, Kreuzer M, Ramirez Saldivar DA, Clauss M.

Front Vet Sci. 2018 Jan 19;4:246. doi: 10.3389/fvets.2017.00246. eCollection 2017.

44.

[The Measurement Precision and Accuracy of T1 Mapping Using Polarity Corrected (PC) TI Prep Tool].

Ishikawa H, Seino S, Takasumi H, Kikori K, Harata M, Kanezawa T, Watanabe N, Satou T, Nishina T, Kuhara S.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2018;74(1):13-21. doi: 10.6009/jjrt.2018_JSRT_74.1.13. Japanese.

45.

Effects of Low-Dose Dairy Protein Plus Micronutrient Supplementation during Resistance Exercise on Muscle Mass and Physical Performance in Older Adults: A Randomized, Controlled Trial.

Seino S, Sumi K, Narita M, Yokoyama Y, Ashida K, Kitamura A, Shinkai S.

J Nutr Health Aging. 2018;22(1):59-67. doi: 10.1007/s12603-017-0904-5.

PMID:
29300423
46.

Clinical trials using mesenchymal stem cells in liver diseases and inflammatory bowel diseases.

Tsuchiya A, Kojima Y, Ikarashi S, Seino S, Watanabe Y, Kawata Y, Terai S.

Inflamm Regen. 2017 Jul 3;37:16. doi: 10.1186/s41232-017-0045-6. eCollection 2017. Review.

47.

Older Korean adults have lower physical function despite longer exercise times compared to their Japanese counterparts: A Japan-Korea comparative study.

Jung S, Okubo Y, Osuka Y, Seino S, Park J, Nho H, Tanaka K.

Geriatr Gerontol Int. 2018 Apr;18(4):576-583. doi: 10.1111/ggi.13218. Epub 2017 Dec 7.

PMID:
29218770
48.

Repositioning CEP-1347, a chemical agent originally developed for the treatment of Parkinson's disease, as an anti-cancer stem cell drug.

Okada M, Takeda H, Sakaki H, Kuramoto K, Suzuki S, Sanomachi T, Togashi K, Seino S, Kitanaka C.

Oncotarget. 2017 Oct 24;8(55):94872-94882. doi: 10.18632/oncotarget.22033. eCollection 2017 Nov 7.

49.

Antitumor activity of gemcitabine against high-grade meningioma in vitro and in vivo.

Takeda H, Okada M, Kuramoto K, Suzuki S, Sakaki H, Sanomachi T, Seino S, Yoshioka T, Hirano H, Arita K, Kitanaka C.

Oncotarget. 2017 Jun 29;8(53):90996-91008. doi: 10.18632/oncotarget.18827. eCollection 2017 Oct 31.

50.

Albumin, Hemoglobin, and the Trajectory of Cognitive Function in Community-Dwelling Older Japanese: A 13-Year Longitudinal Study.

Murayama H, Shinkai S, Nishi M, Taniguchi Y, Amano H, Seino S, Yokoyama Y, Yoshida H, Fujiwara Y, Ito H.

J Prev Alzheimers Dis. 2017;4(2):93-99. doi: 10.14283/jpad.2016.113.

PMID:
29186279

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