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Items: 1 to 50 of 510

1.

Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12.

Wu X, Schnitzler GR, Gao GF, Diamond B, Baker AR, Kaplan B, Williamson K, Westlake L, Lorrey S, Lewis TA, Garvie CW, Lange M, Hayat S, Seidel H, Doench J, Cherniack AD, Kopitz C, Meyerson M, Greulich H.

J Biol Chem. 2020 Jan 31. pii: jbc.RA119.011191. doi: 10.1074/jbc.RA119.011191. [Epub ahead of print]

2.

Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis.

Chianelli D, Rucker PV, Roland J, Tully DC, Nelson J, Liu X, Bursulaya B, Hernandez ED, Wu J, Prashad M, Schlama T, Liu Y, Chu A, Schmeits J, Huang DJ, Hill R, Bao D, Zoll J, Kim Y, Groessl T, McNamara P, Liu B, Richmond W, Sancho-Martinez I, Phimister A, Seidel HM, Badman MK, Joseph SB, Laffitte B, Molteni V.

J Med Chem. 2020 Feb 5. doi: 10.1021/acs.jmedchem.9b01621. [Epub ahead of print]

PMID:
31940200
3.

Case-matched Comparison of Cardiovascular Outcome in Loeys-Dietz Syndrome versus Marfan Syndrome.

Mühlstädt K, De Backer J, von Kodolitsch Y, Kutsche K, Muiño Mosquera L, Brickwedel J, Girdauskas E, Mir TS, Mahlmann A, Tsilimparis N, Staebler A, Schoof L, Seidel H, Berger J, Bernhardt AM, Blankenberg S, Kölbel T, Detter C, Szöcs K, Kaemmerer H.

J Clin Med. 2019 Nov 29;8(12). pii: E2079. doi: 10.3390/jcm8122079.

4.

Long-term outcomes of childhood onset Noonan compared to sarcomere hypertrophic cardiomyopathy.

Kaltenecker E, Schleihauf J, Meierhofer C, Shehu N, Mkrtchyan N, Hager A, Kühn A, Cleuziou J, Klingel K, Seidel H, Zenker M, Ewert P, Hessling G, Wolf CM.

Cardiovasc Diagn Ther. 2019 Oct;9(Suppl 2):S299-S309. doi: 10.21037/cdt.2019.05.01.

5.

Hemostatic abnormalities in adult patients with Marfan syndrome.

Kornhuber KTI, Seidel H, Pujol C, Meierhofer C, Röschenthaler F, Pressler A, Stöckl A, Nagdyman N, Neidenbach RC, von Hundelshausen P, Halle M, Holdenrieder S, Ewert P, Kaemmerer H, Hauser M.

Cardiovasc Diagn Ther. 2019 Oct;9(Suppl 2):S209-S220. doi: 10.21037/cdt.2019.08.09.

6.

Compensatory Growth of Scots Pine Seedlings Mitigates Impacts of Multiple Droughts Within and Across Years.

Seidel H, Matiu M, Menzel A.

Front Plant Sci. 2019 Apr 24;10:519. doi: 10.3389/fpls.2019.00519. eCollection 2019.

7.

Generation of Linear Traveling Waves in Piezoelectric Plates in Air and Liquid.

Díaz-Molina A, Ruiz-Díez V, Hernando-García J, Ababneh A, Seidel H, Sánchez-Rojas JL.

Micromachines (Basel). 2019 Apr 27;10(5). pii: E283. doi: 10.3390/mi10050283.

8.

The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies.

Christian S, Merz C, Evans L, Gradl S, Seidel H, Friberg A, Eheim A, Lejeune P, Brzezinka K, Zimmermann K, Ferrara S, Meyer H, Lesche R, Stoeckigt D, Bauser M, Haegebarth A, Sykes DB, Scadden DT, Losman JA, Janzer A.

Leukemia. 2019 Oct;33(10):2403-2415. doi: 10.1038/s41375-019-0461-5. Epub 2019 Apr 2.

PMID:
30940908
9.

A Perception-driven Hybrid Decomposition for Multi-layer Accommodative Displays.

Yu H, Bemana M, Wernikowski M, Chwesiuk M, Tursun OT, Singh G, Myszkowski K, Mantiuk R, Seidel HP, Didyk P.

IEEE Trans Vis Comput Graph. 2019 May;25(5):1940-1950. doi: 10.1109/TVCG.2019.2898821. Epub 2019 Feb 18.

PMID:
30794180
10.

Mo2Cap2: Real-time Mobile 3D Motion Capture with a Cap-mounted Fisheye Camera.

Xu W, Chatterjee A, Zollhofer M, Rhodin H, Fua P, Seidel HP, Theobalt C.

IEEE Trans Vis Comput Graph. 2019 May;25(5):2093-2101. doi: 10.1109/TVCG.2019.2898650. Epub 2019 Feb 15.

PMID:
30794176
11.

Biomarkers Associated With Response to Regorafenib in Patients With Hepatocellular Carcinoma.

Teufel M, Seidel H, Köchert K, Meinhardt G, Finn RS, Llovet JM, Bruix J.

Gastroenterology. 2019 May;156(6):1731-1741. doi: 10.1053/j.gastro.2019.01.261. Epub 2019 Feb 6.

12.

A Geometrical Study on the Roof Tile-Shaped Modes in AlN-Based Piezoelectric Microcantilevers as Viscosity⁻Density Sensors.

Ruiz-Díez V, Toledo J, Hernando-García J, Ababneh A, Seidel H, Sánchez-Rojas JL.

Sensors (Basel). 2019 Feb 6;19(3). pii: E658. doi: 10.3390/s19030658.

13.

Evaluation of a semi-automated von Willebrand factor multimer assay, the Hydragel 5 von Willebrand multimer, by two European Centers.

Bowyer AE, Goodfellow KJ, Seidel H, Westhofen P, Stufano F, Goodeve A, Kitchen S, Makris M.

Res Pract Thromb Haemost. 2018 Aug 12;2(4):790-799. doi: 10.1002/rth2.12141. eCollection 2018 Oct.

14.

Publisher Correction: Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study.

Hellenkamp B, Schmid S, Doroshenko O, Opanasyuk O, Kühnemuth R, Adariani SR, Ambrose B, Aznauryan M, Barth A, Birkedal V, Bowen ME, Chen H, Cordes T, Eilert T, Fijen C, Gebhardt C, Götz M, Gouridis G, Gratton E, Ha T, Hao P, Hanke CA, Hartmann A, Hendrix J, Hildebrandt LL, Hirschfeld V, Hohlbein J, Hua B, Hübner CG, Kallis E, Kapanidis AN, Kim JY, Krainer G, Lamb DC, Lee NK, Lemke EA, Levesque B, Levitus M, McCann JJ, Naredi-Rainer N, Nettels D, Ngo T, Qiu R, Robb NC, Röcker C, Sanabria H, Schlierf M, Schröder T, Schuler B, Seidel H, Streit L, Thurn J, Tinnefeld P, Tyagi S, Vandenberk N, Vera AM, Weninger KR, Wünsch B, Yanez-Orozco IS, Michaelis J, Seidel CAM, Craggs TD, Hugel T.

Nat Methods. 2018 Nov;15(11):984. doi: 10.1038/s41592-018-0193-x.

PMID:
30327572
15.

Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study.

Hellenkamp B, Schmid S, Doroshenko O, Opanasyuk O, Kühnemuth R, Rezaei Adariani S, Ambrose B, Aznauryan M, Barth A, Birkedal V, Bowen ME, Chen H, Cordes T, Eilert T, Fijen C, Gebhardt C, Götz M, Gouridis G, Gratton E, Ha T, Hao P, Hanke CA, Hartmann A, Hendrix J, Hildebrandt LL, Hirschfeld V, Hohlbein J, Hua B, Hübner CG, Kallis E, Kapanidis AN, Kim JY, Krainer G, Lamb DC, Lee NK, Lemke EA, Levesque B, Levitus M, McCann JJ, Naredi-Rainer N, Nettels D, Ngo T, Qiu R, Robb NC, Röcker C, Sanabria H, Schlierf M, Schröder T, Schuler B, Seidel H, Streit L, Thurn J, Tinnefeld P, Tyagi S, Vandenberk N, Vera AM, Weninger KR, Wünsch B, Yanez-Orozco IS, Michaelis J, Seidel CAM, Craggs TD, Hugel T.

Nat Methods. 2018 Sep;15(9):669-676. doi: 10.1038/s41592-018-0085-0. Epub 2018 Aug 31. Erratum in: Nat Methods. 2018 Nov;15(11):984.

16.

Targeting the NLRP3 inflammasome in inflammatory diseases.

Mangan MSJ, Olhava EJ, Roush WR, Seidel HM, Glick GD, Latz E.

Nat Rev Drug Discov. 2018 Sep;17(9):688. doi: 10.1038/nrd.2018.149. Epub 2018 Aug 17.

PMID:
30116046
17.

C. elegans germ cells divide and differentiate in a folded tissue.

Seidel HS, Smith TA, Evans JK, Stamper JQ, Mast TG, Kimble J.

Dev Biol. 2018 Oct 1;442(1):173-187. doi: 10.1016/j.ydbio.2018.07.013. Epub 2018 Jul 19.

18.

Targeting the NLRP3 inflammasome in inflammatory diseases.

Mangan MSJ, Olhava EJ, Roush WR, Seidel HM, Glick GD, Latz E.

Nat Rev Drug Discov. 2018 Aug;17(8):588-606. doi: 10.1038/nrd.2018.97. Epub 2018 Jul 20. Review. Erratum in: Nat Rev Drug Discov. 2018 Sep;17(9):688.

PMID:
30026524
19.

Monitoring of argatroban and lepirudin anticoagulation in critically ill patients by conventional laboratory parameters and rotational thromboelastometry - a prospectively controlled randomized double-blind clinical trial.

Beiderlinden M, Werner P, Bahlmann A, Kemper J, Brezina T, Schäfer M, Görlinger K, Seidel H, Kienbaum P, Treschan TA.

BMC Anesthesiol. 2018 Feb 9;18(1):18. doi: 10.1186/s12871-018-0475-y.

20.

Ellis-van Creveld syndrome and profound deafness resulted by sequence variants in the EVC/EVC2 and TMC1 genes.

Umair M, Seidel H, Ahmed I, Ullah A, Haack TB, Alhaddad B, Jan A, Rafique A, Strom TM, Ahmad F, Meitinger T, Ahmad W.

J Genet. 2017 Dec;96(6):1005-1014.

21.

Lower prevalence of vitamin D insufficiency in German patients with systemic mast cell activation syndrome compared with the general population.

Wirz S, Hertfelder HJ, Seidel H, Homann J, Molderings GJ.

Z Gastroenterol. 2017 Dec;55(12):1297-1306. doi: 10.1055/s-0043-121346. Epub 2017 Dec 6.

PMID:
29212100
22.

Corrigendum to: 'Clinical long-term outcome of septal myectomy for obstructive hypertrophic cardiomyopathy in infants' [Eur J Cardiothorac Surg 2018;53:538--44].

Schleihauf J, Cleuziou J, Pabst von Ohain J, Meierhofer C, Stern H, Shehu N, Mkrtchyan N, Kaltenecker E, Kühn A, Nagdyman N, Hager A, Seidel H, Lange R, Ewert P, Wolf CM.

Eur J Cardiothorac Surg. 2018 Mar 1;53(3):694. doi: 10.1093/ejcts/ezx441. No abstract available.

PMID:
29211880
23.

Discovery of Tropifexor (LJN452), a Highly Potent Non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH).

Tully DC, Rucker PV, Chianelli D, Williams J, Vidal A, Alper PB, Mutnick D, Bursulaya B, Schmeits J, Wu X, Bao D, Zoll J, Kim Y, Groessl T, McNamara P, Seidel HM, Molteni V, Liu B, Phimister A, Joseph SB, Laffitte B.

J Med Chem. 2017 Dec 28;60(24):9960-9973. doi: 10.1021/acs.jmedchem.7b00907. Epub 2017 Dec 8.

PMID:
29148806
24.

Clinical long-term outcome of septal myectomy for obstructive hypertrophic cardiomyopathy in infants.

Schleihauf J, Cleuziou J, Pabst von Ohain J, Meierhofer C, Stern H, Shehu N, Mkrtchyan N, Kaltenecker E, Kühn A, Nagdyman N, Hager A, Seidel H, Lange R, Ewert P, Wolf CM.

Eur J Cardiothorac Surg. 2018 Mar 1;53(3):538-544. doi: 10.1093/ejcts/ezx369. Erratum in: Eur J Cardiothorac Surg. 2018 Mar 1;53(3):694.

PMID:
29088344
25.

Phosphatidylinositol 3-Kinase Inhibition by Copanlisib in Relapsed or Refractory Indolent Lymphoma.

Dreyling M, Santoro A, Mollica L, Leppä S, Follows GA, Lenz G, Kim WS, Nagler A, Panayiotidis P, Demeter J, Özcan M, Kosinova M, Bouabdallah K, Morschhauser F, Stevens DA, Trevarthen D, Giurescu M, Cupit L, Liu L, Köchert K, Seidel H, Peña C, Yin S, Hiemeyer F, Garcia-Vargas J, Childs BH, Zinzani PL.

J Clin Oncol. 2017 Dec 10;35(35):3898-3905. doi: 10.1200/JCO.2017.75.4648. Epub 2017 Oct 4. Erratum in: J Clin Oncol. 2018 Feb 10;36(5):521.

PMID:
28976790
26.

Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons.

Zdraljevic S, Strand C, Seidel HS, Cook DE, Doench JG, Andersen EC.

PLoS Genet. 2017 Jul 12;13(7):e1006891. doi: 10.1371/journal.pgen.1006891. eCollection 2017 Jul.

27.

Perceptual Real-Time 2D-to-3D Conversion Using Cue Fusion.

Leimkuhler T, Kellnhofer P, Ritschel T, Myszkowski K, Seidel HP.

IEEE Trans Vis Comput Graph. 2018 Jun;24(6):2037-2050. doi: 10.1109/TVCG.2017.2703612. Epub 2017 May 11.

PMID:
28504938
28.

Contrasting Hydraulic Architectures of Scots Pine and Sessile Oak at Their Southernmost Distribution Limits.

Martínez-Sancho E, Dorado-Liñán I, Hacke UG, Seidel H, Menzel A.

Front Plant Sci. 2017 Apr 20;8:598. doi: 10.3389/fpls.2017.00598. eCollection 2017.

29.

Monitoring of Argatroban and Lepirudin: What is the Input of Laboratory Values in "Real Life"?

Seidel H, Kolde HJ.

Clin Appl Thromb Hemost. 2018 Mar;24(2):287-294. doi: 10.1177/1076029617699087. Epub 2017 Mar 21.

30.

Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling.

Chen CW, Beyer C, Liu J, Maier C, Li C, Trinh-Minh T, Xu X, Cole SH, Hsieh MH, Ng N, Althage A, Meeusen S, Pan S, Svensson EC, Seidel HM, Schett G, Gergely P, Harris JL, Distler JH.

Ann Rheum Dis. 2017 Apr;76(4):773-778. doi: 10.1136/annrheumdis-2016-210294. Epub 2017 Feb 2.

PMID:
28153829
31.

Phase I/II Study of Refametinib (BAY 86-9766) in Combination with Gemcitabine in Advanced Pancreatic cancer.

Van Laethem JL, Riess H, Jassem J, Haas M, Martens UM, Weekes C, Peeters M, Ross P, Bridgewater J, Melichar B, Cascinu S, Saramak P, Michl P, Van Brummelen D, Zaniboni A, Schmiegel W, Dueland S, Giurescu M, Garosi VL, Roth K, Schulz A, Seidel H, Rajagopalan P, Teufel M, Childs BH.

Target Oncol. 2017 Feb;12(1):97-109. doi: 10.1007/s11523-016-0469-y.

PMID:
27975152
32.

Analysis of the C. elegans Germline Stem Cell Pool.

Crittenden SL, Seidel HS, Kimble J.

Methods Mol Biol. 2017;1463:1-33.

PMID:
27734344
33.

Diverging Drought Resistance of Scots Pine Provenances Revealed by Infrared Thermography.

Seidel H, Schunk C, Matiu M, Menzel A.

Front Plant Sci. 2016 Aug 31;7:1247. doi: 10.3389/fpls.2016.01247. eCollection 2016.

34.

Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer.

Oran AR, Adams CM, Zhang XY, Gennaro VJ, Pfeiffer HK, Mellert HS, Seidel HE, Mascioli K, Kaplan J, Gaballa MR, Shen C, Rigoutsos I, King MP, Cotney JL, Arnold JJ, Sharma SD, Martinez-Outschoorn UE, Vakoc CR, Chodosh LA, Thompson JE, Bradner JE, Cameron CE, Shadel GS, Eischen CM, McMahon SB.

Oncotarget. 2016 Nov 8;7(45):72395-72414. doi: 10.18632/oncotarget.11718.

35.

Above-Ground Dimensions and Acclimation Explain Variation in Drought Mortality of Scots Pine Seedlings from Various Provenances.

Seidel H, Menzel A.

Front Plant Sci. 2016 Jul 7;7:1014. doi: 10.3389/fpls.2016.01014. eCollection 2016.

36.

Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors.

Cheng D, Liu J, Han D, Zhang G, Gao W, Hsieh MH, Ng N, Kasibhatla S, Tompkins C, Li J, Steffy A, Sun F, Li C, Seidel HM, Harris JL, Pan S.

ACS Med Chem Lett. 2016 May 10;7(7):676-80. doi: 10.1021/acsmedchemlett.6b00038. eCollection 2016 Jul 14.

37.

Unraveling the Phosphocholination Mechanism of the Legionella pneumophila Enzyme AnkX.

Gavriljuk K, Schartner J, Seidel H, Dickhut C, Zahedi RP, Hedberg C, Kötting C, Gerwert K.

Biochemistry. 2016 Aug 9;55(31):4375-85. doi: 10.1021/acs.biochem.6b00524. Epub 2016 Jul 27.

PMID:
27404583
38.

Comparison of tissue-interface pressure in healthy subjects lying on two trauma splinting devices: The vacuum mattress splint and long spine board.

Pernik MN, Seidel HH, Blalock RE, Burgess AR, Horodyski M, Rechtine GR, Prasarn ML.

Injury. 2016 Aug;47(8):1801-5. doi: 10.1016/j.injury.2016.05.018. Epub 2016 Jun 4.

PMID:
27324323
39.

Key factors for successful data integration in biomarker research.

Elefsinioti A, Bellaire T, Wang A, Quast K, Seidel H, Braxenthaler M, Goeller G, Christianson A, Henderson D, Reischl J.

Nat Rev Drug Discov. 2016 Jun;15(6):369-70. doi: 10.1038/nrd.2016.74. Epub 2016 May 13.

PMID:
27173942
40.

Expressive Single Scattering for Light Shaft Stylization.

Kol TR, Klehm O, Seidel HP, Eisemann E.

IEEE Trans Vis Comput Graph. 2017 Jul;23(7):1753-1766. doi: 10.1109/TVCG.2016.2554114. Epub 2016 Apr 14.

PMID:
27101611
41.

Genotype and phenotype in patients with Noonan syndrome and a RIT1 mutation.

Kouz K, Lissewski C, Spranger S, Mitter D, Riess A, Lopez-Gonzalez V, Lüttgen S, Aydin H, von Deimling F, Evers C, Hahn A, Hempel M, Issa U, Kahlert AK, Lieb A, Villavicencio-Lorini P, Ballesta-Martinez MJ, Nampoothiri S, Ovens-Raeder A, Puchmajerová A, Satanovskij R, Seidel H, Unkelbach S, Zabel B, Kutsche K, Zenker M.

Genet Med. 2016 Dec;18(12):1226-1234. doi: 10.1038/gim.2016.32. Epub 2016 Apr 21.

PMID:
27101134
42.

Cell-cycle quiescence maintains Caenorhabditis elegans germline stem cells independent of GLP-1/Notch.

Seidel HS, Kimble J.

Elife. 2015 Nov 9;4. pii: e10832. doi: 10.7554/eLife.10832.

43.

Nanoprocessing using near-infrared sub-15 femtosecond laser microscopes.

König K, Seidel H, Afshar M, Klötzer M, Feili D, Straub M.

In: König K, Ostendorf A, editors. Optically Induced Nanostructures: Biomedical and Technical Applications. Berlin: De Gruyter; 2015 Jun 23. Chapter 1.

44.

Multi-field Pattern Matching based on Sparse Feature Sampling.

Wang Z, Seidel HP, Weinkauf T.

IEEE Trans Vis Comput Graph. 2016 Jan;22(1):807-16. doi: 10.1109/TVCG.2015.2467292. Epub 2015 Aug 12.

PMID:
26390479
45.

Fast and Memory-Efficient Topological Denoising of 2D and 3D Scalar Fields.

Günther D, Jacobson A, Reininghaus J, Seidel HP, Sorkine-Hornung O, Weinkauf T.

IEEE Trans Vis Comput Graph. 2014 Dec;20(12):2585-94. doi: 10.1109/TVCG.2014.2346432.

PMID:
26356972
46.

MovExp: A Versatile Visualization Tool for Human-Computer Interaction Studies with 3D Performance and Biomechanical Data.

Palmas G, Bachynskyi M, Oulasvirta A, Seidel HP, Weinkauf T.

IEEE Trans Vis Comput Graph. 2014 Dec;20(12):2359-68. doi: 10.1109/TVCG.2014.2346311.

PMID:
26356950
47.

Strategies from UW-Madison for rescuing biomedical research in the US.

Kimble J, Bement WM, Chang Q, Cox BL, Drinkwater NR, Gourse RL, Hoskins AA, Huttenlocher A, Kreeger PK, Lambert PF, Mailick MR, Miyamoto S, Moss RL, O'Connor-Giles KM, Roopra A, Saha K, Seidel HS.

Elife. 2015 Jun 30;4:e09305. doi: 10.7554/eLife.09305.

48.

Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease.

Miller AT, Dahlberg C, Sandberg ML, Wen BG, Beisner DR, Hoerter JA, Parker A, Schmedt C, Stinson M, Avis J, Cienfuegos C, McPate M, Tranter P, Gosling M, Groot-Kormelink PJ, Dawson J, Pan S, Tian SS, Seidel HM, Cooke MP.

PLoS One. 2015 Jun 29;10(6):e0131071. doi: 10.1371/journal.pone.0131071. eCollection 2015.

49.

(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.

Choi HS, Rucker PV, Wang Z, Fan Y, Albaugh P, Chopiuk G, Gessier F, Sun F, Adrian F, Liu G, Hood T, Li N, Jia Y, Che J, McCormack S, Li A, Li J, Steffy A, Culazzo A, Tompkins C, Phung V, Kreusch A, Lu M, Hu B, Chaudhary A, Prashad M, Tuntland T, Liu B, Harris J, Seidel HM, Loren J, Molteni V.

ACS Med Chem Lett. 2015 Mar 16;6(5):562-7. doi: 10.1021/acsmedchemlett.5b00050. eCollection 2015 May 14.

50.

A Powerful New Quantitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains.

Andersen EC, Shimko TC, Crissman JR, Ghosh R, Bloom JS, Seidel HS, Gerke JP, Kruglyak L.

G3 (Bethesda). 2015 Mar 13;5(5):911-20. doi: 10.1534/g3.115.017178.

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