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Items: 1 to 50 of 75

1.

Expression of MATE1, P-gp, OCTN1 and OCTN2, in epithelial and immune cells in the lung of COPD and healthy individuals.

Berg T, Hegelund-Myrbäck T, Öckinger J, Zhou XH, Brännström M, Hagemann-Jensen M, Werkström V, Seidegård J, Grunewald J, Nord M, Gustavsson L.

Respir Res. 2018 Apr 20;19(1):68. doi: 10.1186/s12931-018-0760-9.

2.

Gene expression analysis of membrane transporters and drug-metabolizing enzymes in the lung of healthy and COPD subjects.

Berg T, Hegelund Myrbäck T, Olsson M, Seidegård J, Werkström V, Zhou XH, Grunewald J, Gustavsson L, Nord M.

Pharmacol Res Perspect. 2014 Aug;2(4):e00054. doi: 10.1002/prp2.54. Epub 2014 Jun 12.

3.

Differentiating mucosal and hepatic metabolism of budesonide by local pretreatment with increasing doses of ketoconazole in the proximal jejunum.

Seidegård J, Nyberg L, Borgå O.

Eur J Pharm Sci. 2012 Aug 15;46(5):530-6. doi: 10.1016/j.ejps.2012.04.005. Epub 2012 Apr 17.

PMID:
22538054
4.

Grapefruit juice interaction with oral budesonide: equal effect on immediate-release and delayed-release formulations.

Seidegård J, Randvall G, Nyberg L, Borgå O.

Pharmazie. 2009 Jul;64(7):461-5.

PMID:
19694184
5.

Increased degradation rate of nitrososureas in media containing carbonate.

Seidegård J, Grönquist L, Tuvesson H, Gunnarsson PO.

In Vitro Cell Dev Biol Anim. 2009 Jan-Feb;45(1-2):32-4. doi: 10.1007/s11626-008-9147-4. Epub 2008 Oct 15.

PMID:
18855076
6.

Presystemic elimination of budesonide in man when administered locally at different levels in the gut, with and without local inhibition by ketoconazole.

Seidegård J, Nyberg L, Borgå O.

Eur J Pharm Sci. 2008 Nov 15;35(4):264-70. doi: 10.1016/j.ejps.2008.07.005. Epub 2008 Jul 29.

PMID:
18706998
7.

Expression of cytochromes P450 3A and P-glycoprotein in human large intestine in paired tumour and normal samples.

Canaparo R, Nordmark A, Finnström N, Lundgren S, Seidegård J, Jeppsson B, Edwards RJ, Boobis AR, Rane A.

Basic Clin Pharmacol Toxicol. 2007 Apr;100(4):240-8.

8.

A convenient method for local drug administration at predefined sites in the entire gastrointestinal tract: experiences from 13 phase I studies.

Nyberg L, Månsson W, Abrahamsson B, Seidegård J, Borgå O.

Eur J Pharm Sci. 2007 Apr;30(5):432-40. Epub 2007 Feb 2.

PMID:
17336045
9.

In vitro metabolism and in vivo pharmacokinetics of quinoline 3-carboxamide derivatives in various species.

Tuvesson H, Hallin I, Ellman M, Sparre B, Gunnarsson PO, Seidegård J.

Xenobiotica. 2005 Mar;35(3):293-304.

PMID:
16019952
10.

Cytochrome P450 3A4 is the major enzyme responsible for the metabolism of laquinimod, a novel immunomodulator.

Tuvesson H, Hallin I, Persson R, Sparre B, Gunnarsson PO, Seidegård J.

Drug Metab Dispos. 2005 Jun;33(6):866-72. Epub 2005 Mar 11.

PMID:
15764719
11.

Association of metabolic gene polymorphisms with tobacco consumption in healthy controls.

Smits KM, Benhamou S, Garte S, Weijenberg MP, Alamanos Y, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Boffetta P, Bouchardy C, Brockmoller J, Butkiewicz D, Cascorbi I, Clapper ML, Coutelle C, Daly AK, Muzi G, Dolzan V, Duzhak TG, Farker K, Golka K, Haugen A, Hein DW, Hildesheim A, Hirvonen A, Hsieh LL, Ingelman-Sundberg M, Kalina I, Kang D, Katoh T, Kihara M, Ono-Kihara M, Kim H, Kiyohara C, Kremers P, Lazarus P, Le Marchand L, Lechner MC, London S, Manni JJ, Maugard CM, Morgan GJ, Morita S, Nazar-Stewart V, Kristensen VN, Oda Y, Parl FF, Peters WH, Rannug A, Rebbeck T, Pinto LF, Risch A, Romkes M, Salagovic J, Schoket B, Seidegard J, Shields PG, Sim E, Sinnett D, Strange RC, Stucker I, Sugimura H, To-Figueras J, Vineis P, Yu MC, Zheng W, Pedotti P, Taioli E.

Int J Cancer. 2004 Jun 10;110(2):266-70.

12.

Interaction between smoking, GSTM1 deletion and colorectal cancer: results from the GSEC study.

Smits KM, Gaspari L, Weijenberg MP, Dolzan V, Golka K, Roemer HC, Nedelcheva Kristensen V, Lechner MC, Mehling GI, Seidegard J, Strange RC, Taioli E.

Biomarkers. 2003 May-Aug;8(3-4):299-310.

PMID:
12944179
13.

Antibodies against 5-hydroxymethyl-2'-deoxyuridine are associated with lifestyle factors and GSTM1 genotype: a report from the Malmö Diet and Cancer cohort.

Wallström P, Frenkel K, Wirfält E, Gullberg B, Karkoszka J, Seidegård J, Janzon L, Berglund G.

Cancer Epidemiol Biomarkers Prev. 2003 May;12(5):444-51.

14.

Polymorphisms in CYP1A1, GSTM1, GSTT1 and lung cancer below the age of 45 years.

Taioli E, Gaspari L, Benhamou S, Boffetta P, Brockmoller J, Butkiewicz D, Cascorbi I, Clapper ML, Dolzan V, Haugen A, Hirvonen A, Husgafvel-Pursiainen K, Kalina I, Kremers P, Le Marchand L, London S, Rannug A, Romkes M, Schoket B, Seidegard J, Strange RC, Stucker I, To-Figueras J, Garte S.

Int J Epidemiol. 2003 Feb;32(1):60-3.

PMID:
12690010
15.

Meta- and pooled analyses of the effects of glutathione S-transferase M1 polymorphisms and smoking on lung cancer risk.

Benhamou S, Lee WJ, Alexandrie AK, Boffetta P, Bouchardy C, Butkiewicz D, Brockmöller J, Clapper ML, Daly A, Dolzan V, Ford J, Gaspari L, Haugen A, Hirvonen A, Husgafvel-Pursiainen K, Ingelman-Sundberg M, Kalina I, Kihara M, Kremers P, Le Marchand L, London SJ, Nazar-Stewart V, Onon-Kihara M, Rannug A, Romkes M, Ryberg D, Seidegard J, Shields P, Strange RC, Stücker I, To-Figueras J, Brennan P, Taioli E.

Carcinogenesis. 2002 Aug;23(8):1343-50. Erratum in: Carcinogenesis 2002 Oct;23(10):1771.

PMID:
12151353
16.

Metabolic gene polymorphism frequencies in control populations.

Garte S, Gaspari L, Alexandrie AK, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Benhamou S, Boffetta P, Bouchardy C, Breskvar K, Brockmoller J, Cascorbi I, Clapper ML, Coutelle C, Daly A, Dell'Omo M, Dolzan V, Dresler CM, Fryer A, Haugen A, Hein DW, Hildesheim A, Hirvonen A, Hsieh LL, Ingelman-Sundberg M, Kalina I, Kang D, Kihara M, Kiyohara C, Kremers P, Lazarus P, Le Marchand L, Lechner MC, van Lieshout EM, London S, Manni JJ, Maugard CM, Morita S, Nazar-Stewart V, Noda K, Oda Y, Parl FF, Pastorelli R, Persson I, Peters WH, Rannug A, Rebbeck T, Risch A, Roelandt L, Romkes M, Ryberg D, Salagovic J, Schoket B, Seidegard J, Shields PG, Sim E, Sinnet D, Strange RC, Stücker I, Sugimura H, To-Figueras J, Vineis P, Yu MC, Taioli E.

Cancer Epidemiol Biomarkers Prev. 2001 Dec;10(12):1239-48.

17.

Identification of cytochrome P4503A as the major subfamily responsible for the metabolism of roquinimex in man.

Tuvesson H, Wienkers LC, Gunnarsson PO, Seidegård J, Persson R.

Xenobiotica. 2000 Sep;30(9):905-14.

PMID:
11055268
18.

Influence of glutathione metabolising enzymes in rats with gram-negative sepsis.

Hansson L, Seidegård J, Johansson L, Jeppsson B.

Eur J Surg. 2000 Sep;166(9):728-33.

PMID:
11034470
20.

Metabolism of roquinimex in mouse and rat: an in vitro/in vivo comparison.

Tuvesson H, Strandgården K, Nordle O, Gunnarsson PO, Seidegård J, Persson R.

Xenobiotica. 2000 Apr;30(4):371-80.

PMID:
10821166
21.

Effect of an oral contraceptive on the plasma levels of budesonide and prednisolone and the influence on plasma cortisol.

Seidegård J, Simonsson M, Edsbäcker S.

Clin Pharmacol Ther. 2000 Apr;67(4):373-81.

PMID:
10801246
22.

Metabolism of tauromustine in liver and lung microsomes from various species.

Tuvesson H, Gunnarsson PO, Seidegård J.

Xenobiotica. 1999 Aug;29(8):783-92.

PMID:
10553719
23.

Regulation of rat glutathione S-transferase A5 by cancer chemopreventive agents: mechanisms of inducible resistance to aflatoxin B1.

Hayes JD, Pulford DJ, Ellis EM, McLeod R, James RF, Seidegård J, Mosialou E, Jernström B, Neal GE.

Chem Biol Interact. 1998 Apr 24;111-112:51-67. Review.

PMID:
9679543
24.

Effect of grapefruit juice on urinary 6 beta-hydroxycortisol/cortisol excretion.

Seidegård J, Dahlström K, Kullberg A.

Clin Exp Pharmacol Physiol. 1998 May;25(5):379-81.

PMID:
9612666
25.

Characterization of a human glutathione S-transferase mu cluster containing a duplicated GSTM1 gene that causes ultrarapid enzyme activity.

McLellan RA, Oscarson M, Alexandrie AK, Seidegård J, Evans DA, Rannug A, Ingelman-Sundberg M.

Mol Pharmacol. 1997 Dec;52(6):958-65.

PMID:
9415705
26.

The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics.

Seidegård J, Ekström G.

Environ Health Perspect. 1997 Jun;105 Suppl 4:791-9. Review.

27.

Frequent occurrence of CYP2D6 gene duplication in Saudi Arabians.

McLellan RA, Oscarson M, Seidegård J, Evans DA, Ingelman-Sundberg M.

Pharmacogenetics. 1997 Jun;7(3):187-91.

PMID:
9241658
28.

The GSTM1 genetic polymorphism in healthy Saudi Arabians and Filipinos, and Saudi Arabians with coronary atherosclerosis.

Evans DA, Seidegård J, Narayanan N.

Pharmacogenetics. 1996 Aug;6(4):365-7. No abstract available.

PMID:
8873224
29.

Glutathione and phospholipid depletion of liver tumors after arterial ischemia.

Wang LQ, Persson BG, Xu N, Seidegård J, Jeppsson B, Bengmark S.

J Surg Oncol. 1996 Apr;61(4):284-9.

PMID:
8628000
30.

P53 polymorphisms and haplotypes in lung cancer.

Birgander R, Själander A, Rannug A, Alexandrie AK, Sundberg MI, Seidegård J, Tornling G, Beckman G, Beckman L.

Carcinogenesis. 1995 Sep;16(9):2233-6.

PMID:
7554081
31.
32.

The expression of glutathione transferase mu in patients with inflammatory bowel disease.

Hertervig E, Nilsson A, Seidegård J.

Scand J Gastroenterol. 1994 Aug;29(8):729-35.

PMID:
7973433
33.

Effect of drug scheduling on the antitumor-activity and bone-marrow toxicity of tauromustine (tcnu).

Matthew A, Christensson P, Seidegard J, Tuvesson H, Bibby M, Hartleyasp B, Creaven P.

Int J Oncol. 1994 Feb;4(2):403-9.

PMID:
21566938
34.

Simultaneous pulmonary carcinoma in twins--a case report and review of the literature.

Agrup M, Ekberg L, Albertsson M, Seidegård J.

Acta Oncol. 1994;33(1):82-3. No abstract available.

PMID:
8142135
35.

Glutathione transferase activity in human vessels and in cultured arterial smooth muscle cells.

Pessah-Rasmussen H, Seidegård J, Stavenow L, Solem JO, Lindblad B, Xu CB.

Int Angiol. 1993 Dec;12(4):348-54.

PMID:
8207312
37.

Genetic polymorphism of cytochrome P4502E1 in a Swedish population. Relationship to incidence of lung cancer.

Persson I, Johansson I, Bergling H, Dahl ML, Seidegård J, Rylander R, Rannug A, Högberg J, Sundberg MI.

FEBS Lett. 1993 Mar 22;319(3):207-11.

38.

The Malmö biomarker programme.

Pero RW, Berglund G, Christie NT, Cosma GN, Frenkel K, Garte SJ, Janzon L, Olsson A, Seidegård J, Smulson ME, et al.

J Intern Med. 1993 Jan;233(1):69-74. Review.

PMID:
8429290
39.

Human fibroblasts lacking trans-stilbene oxide active glutathione transferase exhibit increased cell death when exposed to polycyclic aromatic hydrocarbons.

Pessah-Rasmussen H, Stavenow L, Seidegård J, Berglund A.

Pharmacol Toxicol. 1992 May;70(5 Pt 1):361-5.

PMID:
1608925
40.

Eighty-year-old men without cardiovascular disease in the community of Malmö. Part II. Smoking characteristics and ultrasound findings, with special reference to glutathione transferase and pyridoxal-5-phosphate.

Pessah-Rasmussen H, Jerntorp P, Stavenow L, Elmstähl S, Hansen F, Seidegärd J, Galvard H, Brattström L, Hamfelt A.

J Intern Med. 1990 Jul;228(1):17-22.

PMID:
2200836
41.

Metabolism of a novel nitrosourea, tauromustine, in the rat.

Seidegård J, Grönquist L, Gunnarsson PO.

Biochem Pharmacol. 1990 May 1;39(9):1431-6.

PMID:
2334443
42.

Lack of glutathione transferase activity in intermittent claudication.

Pessah-Rasmussen H, Stavenow L, Seidegard J, Solem JO, Israelsson B.

Int Angiol. 1990 Apr-Jun;9(2):70-4.

PMID:
2254677
43.

Isoenzyme(s) of glutathione transferase (class Mu) as a marker for the susceptibility to lung cancer: a follow up study.

Seidegård J, Pero RW, Markowitz MM, Roush G, Miller DG, Beattie EJ.

Carcinogenesis. 1990 Jan;11(1):33-6.

PMID:
2295125
44.
45.

DNA repair synthesis in individuals with and without a family history of cancer.

Pero RW, Johnson DB, Markowitz M, Doyle G, Lund-Pero M, Seidegard J, Halper M, Miller DG.

Carcinogenesis. 1989 Apr;10(4):693-7.

PMID:
2702717
46.
47.

The genetic variation and the expression of human glutathione transferase mu.

Seidegård J, Pero RW.

Klin Wochenschr. 1988;66 Suppl 11:125-6.

PMID:
3184770
49.

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