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Items: 30

1.

Close inbreeding and low genetic diversity in Inner Asian human populations despite geographical exogamy.

Marchi N, Mennecier P, Georges M, Lafosse S, Hegay T, Dorzhu C, Chichlo B, Ségurel L, Heyer E.

Sci Rep. 2018 Jun 20;8(1):9397. doi: 10.1038/s41598-018-27047-3.

2.

[Importance of intestinal paleomicrobiome study for contemporaneous medical problematics].

Charlier P, Augias A, Sansonetti P, Bon C, Kennedy S, Segurel L.

Med Sci (Paris). 2017 Nov;33(11):984-990. doi: 10.1051/medsci/20173311016. Epub 2017 Dec 4. Review. French.

3.

Gut Protozoa: Friends or Foes of the Human Gut Microbiota?

Chabé M, Lokmer A, Ségurel L.

Trends Parasitol. 2017 Dec;33(12):925-934. doi: 10.1016/j.pt.2017.08.005. Epub 2017 Sep 1. Review.

PMID:
28870496
4.

On the Evolution of Lactase Persistence in Humans.

Ségurel L, Bon C.

Annu Rev Genomics Hum Genet. 2017 Aug 31;18:297-319. doi: 10.1146/annurev-genom-091416-035340. Epub 2017 Apr 19. Review.

PMID:
28426286
5.

Sex-specific genetic diversity is shaped by cultural factors in Inner Asian human populations.

Marchi N, Hegay T, Mennecier P, Georges M, Laurent R, Whitten M, Endicott P, Aldashev A, Dorzhu C, Nasyrova F, Chichlo B, Ségurel L, Heyer E.

Am J Phys Anthropol. 2017 Apr;162(4):627-640. doi: 10.1002/ajpa.23151. Epub 2017 Feb 3.

PMID:
28158897
6.

Latitude as a co-driver of human gut microbial diversity?

Dikongué E, Ségurel L.

Bioessays. 2017 Mar;39(3). doi: 10.1002/bies.201600145. Epub 2017 Jan 13. Review.

PMID:
28083908
7.

Erratum: Detection and interpretation of shared genetic influences on 42 human traits.

Pickrell JK, Berisa T, Liu JZ, Ségurel L, Tung JY, Hinds DA.

Nat Genet. 2016 Sep 28;48(10):1296. doi: 10.1038/ng1016-1296a. No abstract available.

PMID:
27681293
8.

Detection of Allelic Frequency Differences between the Sexes in Humans: A Signature of Sexually Antagonistic Selection.

Lucotte EA, Laurent R, Heyer E, Ségurel L, Toupance B.

Genome Biol Evol. 2016 Jun 2;8(5):1489-500. doi: 10.1093/gbe/evw090.

9.

Detection and interpretation of shared genetic influences on 42 human traits.

Pickrell JK, Berisa T, Liu JZ, Ségurel L, Tung JY, Hinds DA.

Nat Genet. 2016 Jul;48(7):709-17. doi: 10.1038/ng.3570. Epub 2016 May 16. Erratum in: Nat Genet. 2016 Sep 28;48(10):1296.

10.

Variation in Rural African Gut Microbiota Is Strongly Correlated with Colonization by Entamoeba and Subsistence.

Morton ER, Lynch J, Froment A, Lafosse S, Heyer E, Przeworski M, Blekhman R, Ségurel L.

PLoS Genet. 2015 Nov 30;11(11):e1005658. doi: 10.1371/journal.pgen.1005658. eCollection 2015 Nov.

11.

Microsatellite data show recent demographic expansions in sedentary but not in nomadic human populations in Africa and Eurasia.

Aime C, Verdu P, Ségurel L, Martinez-Cruz B, Hegay T, Heyer E, Austerlitz F.

Eur J Hum Genet. 2015 Nov;23(11):1592. doi: 10.1038/ejhg.2014.276. No abstract available.

12.

Preserving immune diversity through ancient inheritance and admixture.

Ségurel L, Quintana-Murci L.

Curr Opin Immunol. 2014 Oct;30:79-84. doi: 10.1016/j.coi.2014.08.002. Epub 2014 Sep 3. Review.

PMID:
25190608
13.

Determinants of mutation rate variation in the human germline.

Ségurel L, Wyman MJ, Przeworski M.

Annu Rev Genomics Hum Genet. 2014;15:47-70. doi: 10.1146/annurev-genom-031714-125740. Epub 2014 Jun 5. Review.

PMID:
25000986
14.

TroX: a new method to learn about the genesis of aneuploidy from trisomic products of conception.

Kermany AR, Segurel L, Oliver TR, Przeworski M.

Bioinformatics. 2014 Jul 15;30(14):2035-42. doi: 10.1093/bioinformatics/btu159. Epub 2014 Mar 21.

15.

Microsatellite data show recent demographic expansions in sedentary but not in nomadic human populations in Africa and Eurasia.

Aimé C, Verdu P, Ségurel L, Martinez-Cruz B, Hegay T, Heyer E, Austerlitz F.

Eur J Hum Genet. 2014 Oct;22(10):1201-7. doi: 10.1038/ejhg.2014.2. Epub 2014 Feb 12. Erratum in: Eur J Hum Genet. 2015 Nov;23(11):1592.

16.

Human genetic data reveal contrasting demographic patterns between sedentary and nomadic populations that predate the emergence of farming.

Aimé C, Laval G, Patin E, Verdu P, Ségurel L, Chaix R, Hegay T, Quintana-Murci L, Heyer E, Austerlitz F.

Mol Biol Evol. 2013 Dec;30(12):2629-44. doi: 10.1093/molbev/mst156. Epub 2013 Sep 24.

PMID:
24063884
17.

Ancestry runs deeper than blood: the evolutionary history of ABO points to cryptic variation of functional importance.

Ségurel L, Gao Z, Przeworski M.

Bioessays. 2013 Oct;35(10):862-7. doi: 10.1002/bies.201300030. Epub 2013 Jul 9.

18.

The complex binding of PRDM9.

Ségurel L.

Genome Biol. 2013 Apr 24;14(4):112. doi: 10.1186/gb-2013-14-1-112.

19.

Multiple instances of ancient balancing selection shared between humans and chimpanzees.

Leffler EM, Gao Z, Pfeifer S, Ségurel L, Auton A, Venn O, Bowden R, Bontrop R, Wall JD, Sella G, Donnelly P, McVean G, Przeworski M.

Science. 2013 Mar 29;339(6127):1578-82. doi: 10.1126/science.1234070. Epub 2013 Feb 14.

20.

Positive selection of protective variants for type 2 diabetes from the Neolithic onward: a case study in Central Asia.

Ségurel L, Austerlitz F, Toupance B, Gautier M, Kelley JL, Pasquet P, Lonjou C, Georges M, Voisin S, Cruaud C, Couloux A, Hegay T, Aldashev A, Vitalis R, Heyer E.

Eur J Hum Genet. 2013 Oct;21(10):1146-51. doi: 10.1038/ejhg.2012.295. Epub 2013 Jan 23.

21.

The ABO blood group is a trans-species polymorphism in primates.

Ségurel L, Thompson EE, Flutre T, Lovstad J, Venkat A, Margulis SW, Moyse J, Ross S, Gamble K, Sella G, Ober C, Przeworski M.

Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18493-8. doi: 10.1073/pnas.1210603109. Epub 2012 Oct 22. Erratum in: Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6607.

22.

Revisiting an old riddle: what determines genetic diversity levels within species?

Leffler EM, Bullaughey K, Matute DR, Meyer WK, Ségurel L, Venkat A, Andolfatto P, Przeworski M.

PLoS Biol. 2012;10(9):e1001388. doi: 10.1371/journal.pbio.1001388. Epub 2012 Sep 11.

23.

A fine-scale chimpanzee genetic map from population sequencing.

Auton A, Fledel-Alon A, Pfeifer S, Venn O, Ségurel L, Street T, Leffler EM, Bowden R, Aneas I, Broxholme J, Humburg P, Iqbal Z, Lunter G, Maller J, Hernandez RD, Melton C, Venkat A, Nobrega MA, Bontrop R, Myers S, Donnelly P, Przeworski M, McVean G.

Science. 2012 Apr 13;336(6078):193-8. doi: 10.1126/science.1216872. Epub 2012 Mar 15.

24.

The case of the fickle fingers: how the PRDM9 zinc finger protein specifies meiotic recombination hotspots in humans.

Ségurel L, Leffler EM, Przeworski M.

PLoS Biol. 2011 Dec;9(12):e1001211. doi: 10.1371/journal.pbio.1001211. Epub 2011 Dec 6. Review.

25.

Lactase persistence in central Asia: phenotype, genotype, and evolution.

Heyer E, Brazier L, Ségurel L, Hegay T, Austerlitz F, Quintana-Murci L, Georges M, Pasquet P, Veuille M.

Hum Biol. 2011 Jun;83(3):379-92. doi: 10.3378/027.083.0304.

PMID:
21740154
26.

In the heartland of Eurasia: the multilocus genetic landscape of Central Asian populations.

Martínez-Cruz B, Vitalis R, Ségurel L, Austerlitz F, Georges M, Théry S, Quintana-Murci L, Hegay T, Aldashev A, Nasyrova F, Heyer E.

Eur J Hum Genet. 2011 Feb;19(2):216-23. doi: 10.1038/ejhg.2010.153. Epub 2010 Sep 8.

27.

Looking for signatures of sex-specific demography and local adaptation on the X chromosome.

Heyer E, Segurel L.

Genome Biol. 2010 Jan 28;11(1):203. doi: 10.1186/gb-2010-11-1-203. Review.

28.

Frequency of the AGT Pro11Leu polymorphism in humans: Does diet matter?

Ségurel L, Lafosse S, Heyer E, Vitalis R.

Ann Hum Genet. 2010 Jan;74(1):57-64. doi: 10.1111/j.1469-1809.2009.00549.x.

29.

Genetic diversity and the emergence of ethnic groups in Central Asia.

Heyer E, Balaresque P, Jobling MA, Quintana-Murci L, Chaix R, Segurel L, Aldashev A, Hegay T.

BMC Genet. 2009 Sep 1;10:49. doi: 10.1186/1471-2156-10-49.

30.

Sex-specific genetic structure and social organization in Central Asia: insights from a multi-locus study.

Ségurel L, Martínez-Cruz B, Quintana-Murci L, Balaresque P, Georges M, Hegay T, Aldashev A, Nasyrova F, Jobling MA, Heyer E, Vitalis R.

PLoS Genet. 2008 Sep 26;4(9):e1000200. doi: 10.1371/journal.pgen.1000200.

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