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Items: 10

1.

LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells.

Cebrià-Costa JP, Pascual-Reguant L, Gonzalez-Perez A, Serra-Bardenys G, Querol J, Cosín M, Verde G, Cigliano RA, Sanseverino W, Segura-Bayona S, Iturbide A, Andreu D, Nuciforo P, Bernado-Morales C, Rodilla V, Arribas J, Yelamos J, de Herreros AG, Stracker TH, Peiró S.

Oncogene. 2020 Jan;39(1):79-121. doi: 10.1038/s41388-019-0969-1. Epub 2019 Aug 28.

2.

SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance.

Panier S, Maric M, Hewitt G, Mason-Osann E, Gali H, Dai A, Labadorf A, Guervilly JH, Ruis P, Segura-Bayona S, Belan O, Marzec P, Gaillard PHL, Flynn RL, Boulton SJ.

Mol Cell. 2019 Oct 3;76(1):27-43.e11. doi: 10.1016/j.molcel.2019.07.010. Epub 2019 Aug 22.

3.

The Tousled-like kinases regulate genome and epigenome stability: implications in development and disease.

Segura-Bayona S, Stracker TH.

Cell Mol Life Sci. 2019 Oct;76(19):3827-3841. doi: 10.1007/s00018-019-03208-z. Epub 2019 Jul 13. Review.

PMID:
31302748
4.

Tousled-like kinases stabilize replication forks and show synthetic lethality with checkpoint and PARP inhibitors.

Lee SB, Segura-Bayona S, Villamor-Payà M, Saredi G, Todd MAM, Attolini CS, Chang TY, Stracker TH, Groth A.

Sci Adv. 2018 Aug 8;4(8):eaat4985. doi: 10.1126/sciadv.aat4985. eCollection 2018 Aug.

5.

Molecular basis of Tousled-Like Kinase 2 activation.

Mortuza GB, Hermida D, Pedersen AK, Segura-Bayona S, López-Méndez B, Redondo P, Rüther P, Pozdnyakova I, Garrote AM, Muñoz IG, Villamor-Payà M, Jauset C, Olsen JV, Stracker TH, Montoya G.

Nat Commun. 2018 Jun 28;9(1):2535. doi: 10.1038/s41467-018-04941-y.

6.

Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.

Segura-Bayona S, Knobel PA, González-Burón H, Youssef SA, Peña-Blanco A, Coyaud É, López-Rovira T, Rein K, Palenzuela L, Colombelli J, Forrow S, Raught B, Groth A, de Bruin A, Stracker TH.

Cell Death Differ. 2017 Nov;24(11):1872-1885. doi: 10.1038/cdd.2017.108. Epub 2017 Jul 14.

7.

PARP-1/PARP-2 double deficiency in mouse T cells results in faulty immune responses and T lymphomas.

Navarro J, Gozalbo-López B, Méndez AC, Dantzer F, Schreiber V, Martínez C, Arana DM, Farrés J, Revilla-Nuin B, Bueno MF, Ampurdanés C, Galindo-Campos MA, Knobel PA, Segura-Bayona S, Martin-Caballero J, Stracker TH, Aparicio P, Del Val M, Yélamos J.

Sci Rep. 2017 Feb 9;7:41962. doi: 10.1038/srep41962.

8.

GEMC1 is a critical regulator of multiciliated cell differentiation.

Terré B, Piergiovanni G, Segura-Bayona S, Gil-Gómez G, Youssef SA, Attolini CS, Wilsch-Bräuninger M, Jung C, Rojas AM, Marjanović M, Knobel PA, Palenzuela L, López-Rovira T, Forrow S, Huttner WB, Valverde MA, de Bruin A, Costanzo V, Stracker TH.

EMBO J. 2016 May 2;35(9):942-60. doi: 10.15252/embj.201592821. Epub 2016 Mar 1.

9.

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection.

Boersma V, Moatti N, Segura-Bayona S, Peuscher MH, van der Torre J, Wevers BA, Orthwein A, Durocher D, Jacobs JJL.

Nature. 2015 May 28;521(7553):537-540. doi: 10.1038/nature14216. Epub 2015 Mar 23.

10.

FANCJ promotes DNA synthesis through G-quadruplex structures.

Castillo Bosch P, Segura-Bayona S, Koole W, van Heteren JT, Dewar JM, Tijsterman M, Knipscheer P.

EMBO J. 2014 Nov 3;33(21):2521-33. doi: 10.15252/embj.201488663. Epub 2014 Sep 5.

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