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Items: 1 to 50 of 118

1.

Personalized medicine: exploiting druggable vulnerabilities for KRAS-driven lung cancer.

Seguin L, Féral C.

Oncoscience. 2018 Jun 23;5(5-6):124-125. doi: 10.18632/oncoscience.416. eCollection 2018 May. No abstract available.

2.

Dermal Fibroblast SLC3A2 Deficiency Leads to Premature Aging and Loss of Epithelial Homeostasis.

Tissot FS, Estrach S, Boulter E, Cailleteau L, Tosello L, Seguin L, Pisano S, Audebert S, Croce O, Féral CC.

J Invest Dermatol. 2018 Jun 12. pii: S0022-202X(18)32054-2. doi: 10.1016/j.jid.2018.05.026. [Epub ahead of print]

PMID:
29906411
3.

Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma.

Cosset É, Ilmjärv S, Dutoit V, Elliott K, von Schalscha T, Camargo MF, Reiss A, Moroishi T, Seguin L, Gomez G, Moo JS, Preynat-Seauve O, Krause KH, Chneiweiss H, Sarkaria JN, Guan KL, Dietrich PY, Weis SM, Mischel PS, Cheresh DA.

Cancer Cell. 2017 Dec 11;32(6):856-868.e5. doi: 10.1016/j.ccell.2017.10.016. Epub 2017 Nov 30.

PMID:
29198914
4.

Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers.

Seguin L, Camargo MF, Wettersten HI, Kato S, Desgrosellier JS, von Schalscha T, Elliott KC, Cosset E, Lesperance J, Weis SM, Cheresh DA.

Cancer Discov. 2017 Dec;7(12):1464-1479. doi: 10.1158/2159-8290.CD-17-0539. Epub 2017 Sep 11.

PMID:
28893801
5.

Pharmacological characterisation of S 47445, a novel positive allosteric modulator of AMPA receptors.

Bretin S, Louis C, Seguin L, Wagner S, Thomas JY, Challal S, Rogez N, Albinet K, Iop F, Villain N, Bertrand S, Krazem A, Bérachochéa D, Billiald S, Tordjman C, Cordi A, Bertrand D, Lestage P, Danober L.

PLoS One. 2017 Sep 8;12(9):e0184429. doi: 10.1371/journal.pone.0184429. eCollection 2017.

6.

Consuming Ecstasy: Representations of Male and Female Orgasm in Mainstream Pornography.

Séguin LJ, Rodrigue C, Lavigne J.

J Sex Res. 2018 Mar-Apr;55(3):348-356. doi: 10.1080/00224499.2017.1332152. Epub 2017 Jun 20.

PMID:
28632461
7.

How and Where Parents of Infants and Young Children Want to Receive Nutrition Information.

Dexter B, Frank S, Seguin L.

Can J Diet Pract Res. 2016 Dec;77(4):203-205. Epub 2016 Oct 20.

PMID:
27763768
8.

Agomelatine affects rat suprachiasmatic nucleus neurons via melatonin and serotonin receptors.

Yang J, Jin HJ, Mocaër E, Seguin L, Zhao H, Rusak B.

Life Sci. 2016 Jun 15;155:147-54. doi: 10.1016/j.lfs.2016.04.035. Epub 2016 May 24.

PMID:
27269050
9.

Kinase-independent role for CRAF-driving tumour radioresistance via CHK2.

Advani SJ, Camargo MF, Seguin L, Mielgo A, Anand S, Hicks AM, Aguilera J, Franovic A, Weis SM, Cheresh DA.

Nat Commun. 2015 Sep 3;6:8154. doi: 10.1038/ncomms9154.

10.

Glioblastomas require integrin αvβ3/PAK4 signaling to escape senescence.

Franovic A, Elliott KC, Seguin L, Camargo MF, Weis SM, Cheresh DA.

Cancer Res. 2015 Nov 1;75(21):4466-73. doi: 10.1158/0008-5472.CAN-15-0988. Epub 2015 Aug 21.

11.

Poor, Unsafe, and Overweight: The Role of Feeling Unsafe at School in Mediating the Association Among Poverty Exposure, Youth Screen Time, Physical Activity, and Weight Status.

Côté-Lussier C, Fitzpatrick C, Séguin L, Barnett TA.

Am J Epidemiol. 2015 Jul 1;182(1):67-79. doi: 10.1093/aje/kwv005. Epub 2015 Apr 28.

12.

Parenting style and obesity risk in children.

Kakinami L, Barnett TA, Séguin L, Paradis G.

Prev Med. 2015 Jun;75:18-22. doi: 10.1016/j.ypmed.2015.03.005. Epub 2015 Mar 20.

PMID:
25797329
13.

Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance.

Seguin L, Desgrosellier JS, Weis SM, Cheresh DA.

Trends Cell Biol. 2015 Apr;25(4):234-40. doi: 10.1016/j.tcb.2014.12.006. Epub 2015 Jan 5. Review.

14.

Maternal prenatal felt security and infant health at birth interact to predict infant fussing and crying at 12 months postpartum.

Sawada N, Gagné FM, Séguin L, Kramer MS, McNamara H, Platt RW, Goulet L, Meaney MJ, Lydon JE.

Health Psychol. 2015 Aug;34(8):811-9. doi: 10.1037/hea0000152. Epub 2014 Dec 22.

PMID:
25528180
15.

The role of the residential neighborhood in linking youths' family poverty trajectory to decreased feelings of safety at school.

Côté-Lussier C, Barnett TA, Kestens Y, Tu MT, Séguin L.

J Youth Adolesc. 2015 Jun;44(6):1194-207. doi: 10.1007/s10964-014-0214-8. Epub 2014 Nov 12.

PMID:
25388832
16.

Integrin αvβ3 drives slug activation and stemness in the pregnant and neoplastic mammary gland.

Desgrosellier JS, Lesperance J, Seguin L, Gozo M, Kato S, Franovic A, Yebra M, Shattil SJ, Cheresh DA.

Dev Cell. 2014 Aug 11;30(3):295-308. doi: 10.1016/j.devcel.2014.06.005.

17.

Short-term heart rate variability in a population-based sample of 10-year-old children.

Jarrin DC, McGrath JJ, Poirier P, Séguin L, Tremblay RE, Montplaisir JY, Paradis G, Séguin JR.

Pediatr Cardiol. 2015 Jan;36(1):41-8. doi: 10.1007/s00246-014-0962-y. Epub 2014 Jul 24.

18.

Impact of the 2008 economic and financial crisis on child health: a systematic review.

Rajmil L, Fernandez de Sanmamed MJ, Choonara I, Faresjö T, Hjern A, Kozyrskyj AL, Lucas PJ, Raat H, Séguin L, Spencer N, Taylor-Robinson D; International Network for Research in Inequalities in Child Health (INRICH).

Int J Environ Res Public Health. 2014 Jun;11(6):6528-46. Review.

20.

Persistent and occasional poverty and children's food consumption: evidence from a longitudinal Québec birth cohort.

Kakinami L, Gauvin L, Séguin L, Lambert M, Nikiema B, Paradis G.

J Epidemiol Community Health. 2014 Oct;68(10):987-92. doi: 10.1136/jech-2014-203951. Epub 2014 Jun 26.

PMID:
24970765
21.

Targeting the Achilles' heel of drug-resistant cancer stem cells.

Seguin L, Gozo M, Weis SM, Cheresh DA.

Cell Cycle. 2014;13(13):2017-8. doi: 10.4161/cc.29460. Epub 2014 Jun 6. No abstract available.

22.

Variety in the tumor microenvironment: integrin splicing regulates stemness.

Seguin L, Weis SM, Cheresh DA.

Cell Stem Cell. 2014 May 1;14(5):557-8. doi: 10.1016/j.stem.2014.04.011.

23.

An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.

Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, Lippman SM, Desgrosellier JS, Anand S, Weis SM, Cheresh DA.

Nat Cell Biol. 2014 May;16(5):457-68. doi: 10.1038/ncb2953. Epub 2014 Apr 20.

24.

Like melatonin, agomelatine (S20098) increases the amplitude of oscillations of two clock outputs: melatonin and temperature rhythms.

Castanho A, Bothorel B, Seguin L, Mocaër E, Pévet P.

Chronobiol Int. 2014 Apr;31(3):371-81. doi: 10.3109/07420528.2013.860457. Epub 2013 Dec 11.

PMID:
24328729
25.

Poverty's latent effect on adiposity during childhood: evidence from a Québec birth cohort.

Kakinami L, Séguin L, Lambert M, Gauvin L, Nikiema B, Paradis G.

J Epidemiol Community Health. 2014 Mar;68(3):239-45. doi: 10.1136/jech-2012-201881. Epub 2013 Nov 22.

PMID:
24272921
26.

Comparison of three lifecourse models of poverty in predicting cardiovascular disease risk in youth.

Kakinami L, Séguin L, Lambert M, Gauvin L, Nikiema B, Paradis G.

Ann Epidemiol. 2013 Aug;23(8):485-91. doi: 10.1016/j.annepidem.2013.05.012. Epub 2013 Jul 5.

PMID:
23830840
27.

Tracking exposure to child poverty during the first 10 years of life in a Quebec birth cohort.

Séguin L, Nikiema B, Gauvin L, Lambert M, Thanh Tu M, Kakinami L, Paradis G.

Can J Public Health. 2012 Apr 27;103(4):e270-6.

PMID:
23618640
28.

Maternal stress/distress, hormonal pathways and spontaneous preterm birth.

Kramer MS, Lydon J, Goulet L, Kahn S, Dahhou M, Platt RW, Sharma S, Meaney MJ, Séguin L.

Paediatr Perinat Epidemiol. 2013 May;27(3):237-46. doi: 10.1111/ppe.12042. Epub 2013 Mar 4.

PMID:
23574411
29.

Is the obesity epidemic worsening the cardiovascular risk factor profile of children? Evidence from two Québec samples measured 10 years apart.

Kakinami L, Paradis G, O'Loughlin J, Séguin L, Delvin EE, Lambert M.

Ann Hum Biol. 2012 Jul;39(4):322-6. doi: 10.3109/03014460.2012.690889. Epub 2012 Jun 21.

PMID:
22716236
30.

AT₂receptors recruit c-Src, SHP-1 and FAK upon activation by Ang II in PND15 rat hindbrain.

Seguin LR, Villarreal RS, Ciuffo GM.

Neurochem Int. 2012 Jan;60(2):199-207. doi: 10.1016/j.neuint.2011.11.008. Epub 2011 Nov 20.

PMID:
22120166
31.

A MEK-independent role for CRAF in mitosis and tumor progression.

Mielgo A, Seguin L, Huang M, Camargo MF, Anand S, Franovic A, Weis SM, Advani SJ, Murphy EA, Cheresh DA.

Nat Med. 2011 Nov 13;17(12):1641-5. doi: 10.1038/nm.2464.

32.

Understanding the determinants of active transportation to school among children: evidence of environmental injustice from the Quebec Longitudinal Study of Child Development.

Pabayo RA, Gauvin L, Barnett TA, Morency P, Nikiéma B, Séguin L.

Health Place. 2012 Mar;18(2):163-71. doi: 10.1016/j.healthplace.2011.08.017. Epub 2011 Sep 10.

PMID:
21937255
33.

APC(cdh1) mediates degradation of the oncogenic Rho-GEF Ect2 after mitosis.

Liot C, Seguin L, Siret A, Crouin C, Schmidt S, Bertoglio J.

PLoS One. 2011;6(8):e23676. doi: 10.1371/journal.pone.0023676. Epub 2011 Aug 19.

34.

Child asthma and change in elevated depressive symptoms among mothers of children of a birth cohort from Quebec.

Tu MT, Perreault G, Séguin L, Gauvin L.

Women Health. 2011 Jul 22;51(5):461-81. doi: 10.1080/03630242.2011.590876.

PMID:
21797679
35.

The influence of poverty and social support on the perceived health of children born to minority migrant mothers.

Van Hulst A, Séguin L, Zunzunegui MV, Vélez MP, Nikiéma B.

Ethn Health. 2011 Jun;16(3):185-200. doi: 10.1080/13557858.2011.559536.

PMID:
21491286
36.

Memory facilitating effects of agomelatine in the novel object recognition memory paradigm in the rat.

Bertaina-Anglade V, Drieu-La-Rochelle C, Mocaër E, Seguin L.

Pharmacol Biochem Behav. 2011 Jun;98(4):511-7. doi: 10.1016/j.pbb.2011.02.015. Epub 2011 Feb 22.

PMID:
21352847
37.

Purkinje cells express Angiotensin II AT(2) receptors at different developmental stages.

Arce ME, Sánchez SI, Aguilera FL, Seguin LR, Seltzer AM, Ciuffo GM.

Neuropeptides. 2011 Feb;45(1):69-76. doi: 10.1016/j.npep.2010.11.002. Epub 2010 Dec 10.

PMID:
21146214
38.

Agomelatine reverses the decrease in hippocampal cell survival induced by chronic mild stress.

Dagytė G, Crescente I, Postema F, Seguin L, Gabriel C, Mocaër E, Boer JA, Koolhaas JM.

Behav Brain Res. 2011 Mar 17;218(1):121-8. doi: 10.1016/j.bbr.2010.11.045. Epub 2010 Nov 27.

39.

Non-stress-related factors associated with maternal corticotrophin-releasing hormone (CRH) concentration.

Kramer MS, Lydon J, Séguin L, Goulet L, Kahn SR, McNamara H, Genest J, Sharma S, Meaney MJ, Libman M, Dahhou M, Platt RW.

Paediatr Perinat Epidemiol. 2010 Jul 1;24(4):390-7. doi: 10.1111/j.1365-3016.2010.01127.x.

PMID:
20618729
40.

Vaginal douching, bacterial vaginosis, and spontaneous preterm birth.

Luong ML, Libman M, Dahhou M, Chen MF, Kahn SR, Goulet L, Séguin L, Lydon J, McNamara H, Platt RW, Kramer MS.

J Obstet Gynaecol Can. 2010 Apr;32(4):313-320. doi: 10.1016/S1701-2163(16)34474-7.

PMID:
20500937
41.

Poverty and chronic illness in early childhood: a comparison between the United kingdom and Quebec.

Nikiéma B, Spencer N, Séguin L.

Pediatrics. 2010 Mar;125(3):e499-507. doi: 10.1542/peds.2009-0701. Epub 2010 Feb 1.

PMID:
20123770
42.

Mid-trimester maternal plasma cytokines and CRP as predictors of spontaneous preterm birth.

Kramer MS, Kahn SR, Platt RW, Genest J, Chen MF, Goulet L, Séguin L, Lydon J, McNamara H, Libman M, Dahhou M, Lamoureux J, Skogstrand K, Thorsen P.

Cytokine. 2010 Jan;49(1):10-4. doi: 10.1016/j.cyto.2009.08.014. Epub 2009 Sep 26.

PMID:
19783155
43.

Sustained active transportation is associated with a favorable body mass index trajectory across the early school years: findings from the Quebec Longitudinal Study of Child Development birth cohort.

Pabayo R, Gauvin L, Barnett TA, Nikiéma B, Séguin L.

Prev Med. 2010 Jan;50 Suppl 1:S59-64. doi: 10.1016/j.ypmed.2009.08.014. Epub 2009 Sep 19.

PMID:
19769996
44.

Antioxidant vitamins, long-chain fatty acids, and spontaneous preterm birth.

Kramer MS, Kahn SR, Platt RW, Genest J, Rozen R, Chen MF, Goulet L, Séguin L, Dassa C, Lydon J, McNamara H, Dahhou M, Lamoureux J, Evans RW.

Epidemiology. 2009 Sep;20(5):707-13. doi: 10.1097/EDE.0b013e3181a818c5.

PMID:
19568173
45.

Investigating socio-economic disparities in preterm birth: evidence for selective study participation and selection bias.

Kramer MS, Wilkins R, Goulet L, Séguin L, Lydon J, Kahn SR, McNamara H, Dassa C, Dahhou M, Masse A, Miner L, Asselin G, Gauthier H, Ghanem A, Benjamin A, Platt RW; Montreal Prematurity Study Group.

Paediatr Perinat Epidemiol. 2009 Jul;23(4):301-9. doi: 10.1111/j.1365-3016.2009.01042.x.

PMID:
19523077
46.

Stress pathways to spontaneous preterm birth: the role of stressors, psychological distress, and stress hormones.

Kramer MS, Lydon J, Séguin L, Goulet L, Kahn SR, McNamara H, Genest J, Dassa C, Chen MF, Sharma S, Meaney MJ, Thomson S, Van Uum S, Koren G, Dahhou M, Lamoureux J, Platt RW.

Am J Epidemiol. 2009 Jun 1;169(11):1319-26. doi: 10.1093/aje/kwp061. Epub 2009 Apr 10.

PMID:
19363098
47.

Vasculopathic and thrombophilic risk factors for spontaneous preterm birth.

Kramer MS, Kahn SR, Rozen R, Evans R, Platt RW, Chen MF, Goulet L, Séguin L, Dassa C, Lydon J, McNamara H, Dahhou M, Genest J.

Int J Epidemiol. 2009 Jun;38(3):715-23. doi: 10.1093/ije/dyp167. Epub 2009 Mar 31.

PMID:
19336437
48.

Inherited thrombophilia and preeclampsia within a multicenter cohort: the Montreal Preeclampsia Study.

Kahn SR, Platt R, McNamara H, Rozen R, Chen MF, Genest J Jr, Goulet L, Lydon J, Seguin L, Dassa C, Masse A, Asselin G, Benjamin A, Miner L, Ghanem A, Kramer MS.

Am J Obstet Gynecol. 2009 Feb;200(2):151.e1-9; discussion e1-5. doi: 10.1016/j.ajog.2008.09.023. Epub 2008 Dec 13.

PMID:
19070828
49.

CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase.

Seguin L, Liot C, Mzali R, Harada R, Siret A, Nepveu A, Bertoglio J.

Mol Cell Biol. 2009 Jan;29(2):570-81. doi: 10.1128/MCB.01275-08. Epub 2008 Nov 17.

50.

Duration of lack of money for basic needs and growth delay in the Quebec Longitudinal Study of Child Development birth cohort.

Ehounoux NZ, Zunzunegui MV, Séguin L, Nikiema B, Gauvin L; Quebec Longitudinal Study of Child Development Birth Cohort.

J Epidemiol Community Health. 2009 Jan;63(1):45-9. doi: 10.1136/jech.2007.072157. Epub 2008 Sep 9.

PMID:
18782808

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