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Items: 31


Structural evidence for a new elaborate 3D-organization of the cardiomyocyte lateral membrane in adult mammalian cardiac tissues.

Guilbeau-Frugier C, Cauquil M, Karsenty C, Lairez O, Dambrin C, Payré B, Cassard H, Josse C, Seguelas MH, Allart S, Branchereau M, Heymes C, Mandel F, Delisle MB, Pathak A, Dague E, Sénard JM, Galés C.

Cardiovasc Res. 2019 May 1;115(6):1078-1091. doi: 10.1093/cvr/cvy256.


G protein stoichiometry dictates biased agonism through distinct receptor-G protein partitioning.

Onfroy L, Galandrin S, Pontier SM, Seguelas MH, N'Guyen D, Sénard JM, Galés C.

Sci Rep. 2017 Aug 11;7(1):7885. doi: 10.1038/s41598-017-07392-5.


Nanoscale structural mapping as a measure of maturation in the murine frontal cortex.

Smolyakov G, Dague E, Roux C, Seguelas MH, Galés C, Senard JM, Arvanitis DN.

Brain Struct Funct. 2018 Jan;223(1):255-265. doi: 10.1007/s00429-017-1486-z. Epub 2017 Aug 4.


Cardioprotective Angiotensin-(1-7) Peptide Acts as a Natural-Biased Ligand at the Angiotensin II Type 1 Receptor.

Galandrin S, Denis C, Boularan C, Marie J, M'Kadmi C, Pilette C, Dubroca C, Nicaise Y, Seguelas MH, N'Guyen D, Banères JL, Pathak A, Sénard JM, Galés C.

Hypertension. 2016 Dec;68(6):1365-1374. Epub 2016 Oct 3.


Dual agonist occupancy of AT1-R-α2C-AR heterodimers results in atypical Gs-PKA signaling.

Bellot M, Galandrin S, Boularan C, Matthies HJ, Despas F, Denis C, Javitch J, Mazères S, Sanni SJ, Pons V, Seguelas MH, Hansen JL, Pathak A, Galli A, Sénard JM, Galés C.

Nat Chem Biol. 2015 Apr;11(4):271-9. doi: 10.1038/nchembio.1766. Epub 2015 Feb 23.


Cardiac fibroblasts regulate sympathetic nerve sprouting and neurocardiac synapse stability.

Mias C, Coatrieux C, Denis C, Genet G, Seguelas MH, Laplace N, Rouzaud-Laborde C, Calise D, Parini A, Cussac D, Pathak A, Sénard JM, Galés C.

PLoS One. 2013 Nov 14;8(11):e79068. doi: 10.1371/journal.pone.0079068. eCollection 2013.


Role of endothelial AADC in cardiac synthesis of serotonin and nitrates accumulation.

Rouzaud-Laborde C, Hanoun N, Baysal I, Rech JS, Mias C, Calise D, Sicard P, Frugier C, Seguelas MH, Parini A, Pizzinat N.

PLoS One. 2012;7(7):e34893. doi: 10.1371/journal.pone.0034893. Epub 2012 Jul 19.


Deciphering biased-agonism complexity reveals a new active AT1 receptor entity.

Saulière A, Bellot M, Paris H, Denis C, Finana F, Hansen JT, Altié MF, Seguelas MH, Pathak A, Hansen JL, Sénard JM, Galés C.

Nat Chem Biol. 2012 Jul;8(7):622-30. doi: 10.1038/nchembio.961. Epub 2012 May 27.


Ephrin-B1 is a novel specific component of the lateral membrane of the cardiomyocyte and is essential for the stability of cardiac tissue architecture cohesion.

Genet G, Guilbeau-Frugier C, Honton B, Dague E, Schneider MD, Coatrieux C, Calise D, Cardin C, Nieto C, Payré B, Dubroca C, Marck P, Heymes C, Dubrac A, Arvanitis D, Despas F, Altié MF, Seguelas MH, Delisle MB, Davy A, Sénard JM, Pathak A, Galés C.

Circ Res. 2012 Mar 2;110(5):688-700. doi: 10.1161/CIRCRESAHA.111.262451. Epub 2012 Feb 2.


Apelin prevents cardiac fibroblast activation and collagen production through inhibition of sphingosine kinase 1.

Pchejetski D, Foussal C, Alfarano C, Lairez O, Calise D, Guilbeau-Frugier C, Schaak S, Seguelas MH, Wanecq E, Valet P, Parini A, Kunduzova O.

Eur Heart J. 2012 Sep;33(18):2360-9. doi: 10.1093/eurheartj/ehr389. Epub 2011 Oct 25.


Evaluation of alginate microspheres for mesenchymal stem cell engraftment on solid organ.

Trouche E, Girod Fullana S, Mias C, Ceccaldi C, Tortosa F, Seguelas MH, Calise D, Parini A, Cussac D, Sallerin B.

Cell Transplant. 2010;19(12):1623-33. doi: 10.3727/096368910X514297. Epub 2010 Aug 17.


Characterization of monoamine oxidases in mesenchymal stem cells: role in hydrogen peroxide generation and serotonin-dependent apoptosis.

Trouche E, Mias C, Seguelas MH, Ordener C, Cussac D, Parini A.

Stem Cells Dev. 2010 Oct;19(10):1571-8. doi: 10.1089/scd.2009.0353.


Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction.

Mias C, Lairez O, Trouche E, Roncalli J, Calise D, Seguelas MH, Ordener C, Piercecchi-Marti MD, Auge N, Salvayre AN, Bourin P, Parini A, Cussac D.

Stem Cells. 2009 Nov;27(11):2734-43. doi: 10.1002/stem.169.


Platelet derived serotonin drives the activation of rat cardiac fibroblasts by 5-HT2A receptors.

Yabanoglu S, Akkiki M, Seguelas MH, Mialet-Perez J, Parini A, Pizzinat N.

J Mol Cell Cardiol. 2009 Apr;46(4):518-25. doi: 10.1016/j.yjmcc.2008.12.019. Epub 2009 Jan 9.


Ex vivo pretreatment with melatonin improves survival, proangiogenic/mitogenic activity, and efficiency of mesenchymal stem cells injected into ischemic kidney.

Mias C, Trouche E, Seguelas MH, Calcagno F, Dignat-George F, Sabatier F, Piercecchi-Marti MD, Daniel L, Bianchi P, Calise D, Bourin P, Parini A, Cussac D.

Stem Cells. 2008 Jul;26(7):1749-57. doi: 10.1634/stemcells.2007-1000. Epub 2008 May 8.


Vesicular monoamine transporter 1 mediates dopamine secretion in rat proximal tubular cells.

Maurel A, Spreux-Varoquaux O, Amenta F, Tayebati SK, Tomassoni D, Seguelas MH, Parini A, Pizzinat N.

Am J Physiol Renal Physiol. 2007 May;292(5):F1592-8. Epub 2007 Jan 23.


Oxidative stress-dependent sphingosine kinase-1 inhibition mediates monoamine oxidase A-associated cardiac cell apoptosis.

Pchejetski D, Kunduzova O, Dayon A, Calise D, Seguelas MH, Leducq N, Seif I, Parini A, Cuvillier O.

Circ Res. 2007 Jan 5;100(1):41-9. Epub 2006 Dec 7.


Oxidative stress by monoamine oxidase mediates receptor-independent cardiomyocyte apoptosis by serotonin and postischemic myocardial injury.

Bianchi P, Kunduzova O, Masini E, Cambon C, Bani D, Raimondi L, Seguelas MH, Nistri S, Colucci W, Leducq N, Parini A.

Circulation. 2005 Nov 22;112(21):3297-305. Epub 2005 Nov 14.


Involvement of peripheral benzodiazepine receptor in the oxidative stress, death-signaling pathways, and renal injury induced by ischemia-reperfusion.

Kunduzova OR, Escourrou G, De La Farge F, Salvayre R, Séguélas MH, Leducq N, Bono F, Herbert JM, Parini A.

J Am Soc Nephrol. 2004 Aug;15(8):2152-60.


Prevention of apoptotic and necrotic cell death, caspase-3 activation, and renal dysfunction by melatonin after ischemia/reperfusion.

Kunduzova OR, Escourrou G, Seguelas MH, Delagrange P, De La Farge F, Cambon C, Parini A.

FASEB J. 2003 May;17(8):872-4. Epub 2003 Mar 28.


Regulation of JNK/ERK activation, cell apoptosis, and tissue regeneration by monoamine oxidases after renal ischemia-reperfusion.

Kunduzova OR, Bianchi P, Pizzinat N, Escourrou G, Seguelas MH, Parini A, Cambon C.

FASEB J. 2002 Jul;16(9):1129-31. Epub 2002 May 21.


Dopamine induces ERK activation in renal epithelial cells through H2O2 produced by monoamine oxidase.

Vindis C, Séguélas MH, Lanier S, Parini A, Cambon C.

Kidney Int. 2001 Jan;59(1):76-86.


Monoamine oxidase B induces ERK-dependent cell mitogenesis by hydrogen peroxide generation.

Vindis C, Séguélas MH, Bianchi P, Parini A, Cambon C.

Biochem Biophys Res Commun. 2000 Apr 29;271(1):181-5.


Involvement of calcium and arachidonate metabolism in acetylated-low-density-lipoprotein-stimulated tumor-necrosis-factor-alpha production by rat peritoneal macrophages.

Pollaud-Chérion C, Vandaele J, Quartulli F, Séguélas MH, Decerprit J, Pipy B.

Eur J Biochem. 1998 Apr 1;253(1):345-53.


IL-13 induces tyrosine phosphorylation of phospholipase C gamma-1 following IRS-2 association in human monocytes: relationship with the inhibitory effect of IL-13 on ROI production.

Sozzani P, Hasan L, Séguélas MH, Caput D, Ferrara P, Pipy B, Cambon C.

Biochem Biophys Res Commun. 1998 Mar 27;244(3):665-70.


Effect of interleukin-4 on allergen-induced arachidonic acid metabolism of rat peritoneal macrophages during immediate hypersensitivity reactions.

M'Rini C, Escoubet L, Rey A, Béraud M, Lamboeuf Y, Séguelas MH, Besombes, Pipy B.

Biochim Biophys Acta. 1997 Jul 24;1357(3):319-28.


Reactive oxygen intermediates as regulators of TNF-alpha production in rat lung inflammation induced by silica.

Gossart S, Cambon C, Orfila C, Séguélas MH, Lepert JC, Rami J, Carré P, Pipy B.

J Immunol. 1996 Feb 15;156(4):1540-8.


Acetylated low density lipoprotein inhibits the incorporation of arachidonic acid in phospholipids with a concomitant increase of cholesterol arachidonate in rat peritoneal macrophages.

Pollaud C, Krause S, Lepert JC, Orfila C, Séguélas M, Festal D, Decerprit J, Pipy B.

Biochim Biophys Acta. 1995 Dec 7;1259(3):211-9.


Interleukin-13 inhibits protein kinase C-triggered respiratory burst in human monocytes. Role of calcium and cyclic AMP.

Sozzani P, Cambon C, Vita N, Séguélas MH, Caput D, Ferrara P, Pipy B.

J Biol Chem. 1995 Mar 10;270(10):5084-8.


Arachidonic acid metabolism of rat peritoneal macrophages after passive sensitization and allergen challenge.

M'Rini-Puel C, Thardin JF, Forgue MF, Cambon C, Seguelas MH, Pipy B.

Biochim Biophys Acta. 1993 Apr 7;1167(2):165-74.


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