Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 439

1.

Pigment Epithelium-Derived Factor and its Phosphomimetic Mutant Induce JNK-Dependent Apoptosis and P38-Mediated Migration Arrest.

Konson A, Pradeep S, D'Acunto CW, Seger R.

Cell Physiol Biochem. 2018;49(2):512-529. doi: 10.1159/000492990. Epub 2018 Aug 29.

2.

Intrinsically active MEK variants are differentially regulated by proteinases and phosphatases.

Ordan M, Pallara C, Maik-Rachline G, Hanoch T, Gervasio FL, Glaser F, Fernandez-Recio J, Seger R.

Sci Rep. 2018 Aug 7;8(1):11830. doi: 10.1038/s41598-018-30202-5.

3.

Retraction for Plotnikov et al., "Nuclear Extracellular Signal-Regulated Kinase 1 and 2 Translocation Is Mediated by Casein Kinase 2 and Accelerated by Autophosphorylation".

Plotnikov A, Chuderland D, Karamansha Y, Livnah O, Seger R.

Mol Cell Biol. 2018 May 15;38(11). pii: e00106-18. doi: 10.1128/MCB.00106-18. Print 2018 Jun 1. No abstract available.

4.

Retraction for Zehorai and Seger, "Beta-Like Importins Mediate the Nuclear Translocation of Mitogen-Activated Protein Kinases".

Zehorai E, Seger R.

Mol Cell Biol. 2018 May 15;38(11). pii: e00105-18. doi: 10.1128/MCB.00105-18. Print 2018 Jun 1. No abstract available.

5.

Mortality following surgery for trauma in an Indian trauma cohort.

Mansourati M, Kumar V, Khajanchi M, Saha ML, Dharap S, Seger R, Gerdin Wärnberg M.

Br J Surg. 2018 Sep;105(10):1274-1282. doi: 10.1002/bjs.10862. Epub 2018 Apr 17.

PMID:
29665031
6.

The nuclear translocation of the kinases p38 and JNK promotes inflammation-induced cancer.

Maik-Rachline G, Zehorai E, Hanoch T, Blenis J, Seger R.

Sci Signal. 2018 Apr 10;11(525). pii: eaao3428. doi: 10.1126/scisignal.aao3428.

PMID:
29636389
7.

Current Emergency Preparedness Resources and Capabilities Among Academic Health Systems in the United States.

Biddinger PD, Reisman D, Seger RF, Prestipino AL, Sinclair J, Wante B, Goralnick E, Kemen K.

Disaster Med Public Health Prep. 2018 Feb 21:1-4. doi: 10.1017/dmp.2017.131. [Epub ahead of print]

PMID:
29465336
8.

Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells.

Arafeh R, Flores K, Keren-Paz A, Maik-Rachline G, Gutkind N, Rosenberg S, Seger R, Samuels Y.

Sci Rep. 2017 Nov 27;7(1):16345. doi: 10.1038/s41598-017-16558-0.

9.

Expedited Discharge from an Academic Emergency Department: A Pilot Program.

Goldsmith A, Ticona L, Thompson R, White BA, Strauss J, Seger R, Brown DFM, Raja AS, Yun BJ.

J Emerg Med. 2017 Dec;53(6):919-923. doi: 10.1016/j.jemermed.2017.08.075. Epub 2017 Oct 25.

PMID:
29079490
10.

Activation of Signaling Cascades by Weak Extremely Low Frequency Electromagnetic Fields.

Kapri-Pardes E, Hanoch T, Maik-Rachline G, Murbach M, Bounds PL, Kuster N, Seger R.

Cell Physiol Biochem. 2017;43(4):1533-1546. doi: 10.1159/000481977. Epub 2017 Oct 16.

11.

The Role of ERK Signaling in Experimental Autoimmune Encephalomyelitis.

Birkner K, Wasser B, Loos J, Plotnikov A, Seger R, Zipp F, Witsch E, Bittner S.

Int J Mol Sci. 2017 Sep 15;18(9). pii: E1990. doi: 10.3390/ijms18091990.

12.

Correction for Aebersold et al., "Extracellular Signal-Regulated Kinase 1c (ERK1c), a Novel 42-Kilodalton ERK, Demonstrates Unique Modes of Regulation, Localization, and Function".

Aebersold DM, Shaul YD, Yung Y, Yarom N, Yao Z, Hanoch T, Seger R.

Mol Cell Biol. 2017 Aug 28;37(18). pii: e00322-17. doi: 10.1128/MCB.00322-17. Print 2017 Sep 15. No abstract available.

13.

Correction for Zehorai and Seger, "Beta-Like Importins Mediate the Nuclear Translocation of Mitogen-Activated Protein Kinases".

Zehorai E, Seger R.

Mol Cell Biol. 2017 Jul 28;37(16). pii: e00215-17. doi: 10.1128/MCB.00215-17. Print 2017 Aug 15. No abstract available.

14.

GnRH Induces ERK-Dependent Bleb Formation in Gonadotrope Cells, Involving Recruitment of Members of a GnRH Receptor-Associated Signalosome to the Blebs.

Rahamim-Ben Navi L, Tsukerman A, Feldman A, Melamed P, Tomić M, Stojilkovic SS, Boehm U, Seger R, Naor Z.

Front Endocrinol (Lausanne). 2017 Jun 2;8:113. doi: 10.3389/fendo.2017.00113. eCollection 2017.

15.

Role of dynamin, Src, and Ras in the protein kinase C-mediated activation of ERK by gonadotropin-releasing hormone.

Benard O, Naor Z, Seger R.

J Biol Chem. 2017 May 26;292(21):8855. doi: 10.1074/jbc.A117.006995. No abstract available.

16.

ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK.

Yung Y, Yao Z, Hanoch T, Seger R.

J Biol Chem. 2017 May 26;292(21):8854. doi: 10.1074/jbc.A117.910060. No abstract available.

17.

Involvement of the activation loop of ERK in the detachment from cytosolic anchoring.

Wolf I, Rubinfeld H, Yoon S, Marmor G, Hanoch T, Seger R.

J Biol Chem. 2017 May 26;292(21):8853. doi: 10.1074/jbc.A117.103352. No abstract available.

18.

Altered regulation of ERK1b by MEK1 and PTP-SL and modified Elk1 phosphorylation by ERK1b are caused by abrogation of the regulatory C-terminal sequence of ERKs.

Yung Y, Yao Z, Aebersold DM, Hanoch T, Seger R.

J Biol Chem. 2017 May 26;292(21):8852. doi: 10.1074/jbc.A117.105995. No abstract available.

19.

c-Src is activated by the epidermal growth factor receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cells.

Kraus S, Benard O, Naor Z, Seger R.

J Biol Chem. 2017 May 26;292(21):8851. doi: 10.1074/jbc.A117.303886. No abstract available.

20.

Calcium-mediated interactions regulate the subcellular localization of extracellular signal-regulated kinases.

Chuderland D, Marmor G, Shainskaya A, Seger R.

J Biol Chem. 2017 May 26;292(21):8850. doi: 10.1074/jbc.A117.709030. No abstract available.

21.

Pigment epithelium-derived factor and its phosphomimetic mutant induce JNK-dependent apoptosis and p38-mediated migration arrest.

Konson A, Pradeep S, D'Acunto CW, Seger R.

J Biol Chem. 2017 May 26;292(21):8849. doi: 10.1074/jbc.A110.151548. No abstract available.

22.

Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation.

Ben-Ami I, Yao Z, Naor Z, Seger R.

J Biol Chem. 2017 May 26;292(21):8848. doi: 10.1074/jbc.A111.247726. No abstract available.

23.

The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis.

Seger R, Hanoch T, Rosenberg R, Dantes A, Merz WE, Strauss JF 3rd, Amsterdam A.

J Biol Chem. 2017 May 26;292(21):8847. doi: 10.1074/jbc.A117.006852. No abstract available.

24.

High Throughput Analysis of Golgi Structure by Imaging Flow Cytometry.

Wortzel I, Koifman G, Rotter V, Seger R, Porat Z.

Sci Rep. 2017 Apr 11;7(1):788. doi: 10.1038/s41598-017-00909-y.

25.

Direct binding of MEK1 and MEK2 to AKT induces Foxo1 phosphorylation, cellular migration and metastasis.

Procaccia S, Ordan M, Cohen I, Bendetz-Nezer S, Seger R.

Sci Rep. 2017 Feb 22;7:43078. doi: 10.1038/srep43078.

26.

The Nuclear Translocation of ERK.

Berti DA, Seger R.

Methods Mol Biol. 2017;1487:175-194.

PMID:
27924567
27.

A-Kinase Anchoring Protein 4 (AKAP4) is an ERK1/2 substrate and a switch molecule between cAMP/PKA and PKC/ERK1/2 in human spermatozoa.

Rahamim Ben-Navi L, Almog T, Yao Z, Seger R, Naor Z.

Sci Rep. 2016 Nov 30;6:37922. doi: 10.1038/srep37922.

28.

Differential roles of PKC isoforms (PKCs) and Ca2+ in GnRH and phorbol 12-myristate 13-acetate (PMA) stimulation of p38MAPK phosphorylation in immortalized gonadotrope cells.

Mugami S, Kravchook S, Rahamim-Ben Navi L, Seger R, Naor Z.

Mol Cell Endocrinol. 2017 Jan 5;439:141-154. doi: 10.1016/j.mce.2016.10.031. Epub 2016 Nov 1.

PMID:
27810601
29.

Long-term outcomes of 176 patients with X-linked hyper-IgM syndrome treated with or without hematopoietic cell transplantation.

de la Morena MT, Leonard D, Torgerson TR, Cabral-Marques O, Slatter M, Aghamohammadi A, Chandra S, Murguia-Favela L, Bonilla FA, Kanariou M, Damrongwatanasuk R, Kuo CY, Dvorak CC, Meyts I, Chen K, Kobrynski L, Kapoor N, Richter D, DiGiovanni D, Dhalla F, Farmaki E, Speckmann C, Español T, Shcherbina A, Hanson IC, Litzman J, Routes JM, Wong M, Fuleihan R, Seneviratne SL, Small TN, Janda A, Bezrodnik L, Seger R, Raccio AG, Edgar JD, Chou J, Abbott JK, van Montfrans J, González-Granado LI, Bunin N, Kutukculer N, Gray P, Seminario G, Pasic S, Aquino V, Wysocki C, Abolhassani H, Dorsey M, Cunningham-Rundles C, Knutsen AP, Sleasman J, Costa Carvalho BT, Condino-Neto A, Grunebaum E, Chapel H, Ochs HD, Filipovich A, Cowan M, Gennery A, Cant A, Notarangelo LD, Roifman CM.

J Allergy Clin Immunol. 2017 Apr;139(4):1282-1292. doi: 10.1016/j.jaci.2016.07.039. Epub 2016 Sep 30.

30.

Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer.

Weidner P, Söhn M, Gutting T, Friedrich T, Gaiser T, Magdeburg J, Kienle P, Ruh H, Hopf C, Behrens HM, Röcken C, Hanoch T, Seger R, Ebert MP, Burgermeister E.

Oncotarget. 2016 Aug 2;7(31):50490-50506. doi: 10.18632/oncotarget.10466.

31.

The ERK cascade inhibitors: Towards overcoming resistance.

Maik-Rachline G, Seger R.

Drug Resist Updat. 2016 Mar;25:1-12. doi: 10.1016/j.drup.2015.12.001. Epub 2016 Jan 2. Review.

PMID:
27155372
32.

A PARP1-ERK2 synergism is required for the induction of LTP.

Visochek L, Grigoryan G, Kalal A, Milshtein-Parush H, Gazit N, Slutsky I, Yeheskel A, Shainberg A, Castiel A, Seger R, Langelier MF, Dantzer F, Pascal JM, Segal M, Cohen-Armon M.

Sci Rep. 2016 Apr 28;6:24950. doi: 10.1038/srep24950.

33.

Extremely low-frequency magnetic fields and risk of childhood leukemia: A risk assessment by the ARIMMORA consortium.

Schüz J, Dasenbrock C, Ravazzani P, Röösli M, Schär P, Bounds PL, Erdmann F, Borkhardt A, Cobaleda C, Fedrowitz M, Hamnerius Y, Sanchez-Garcia I, Seger R, Schmiegelow K, Ziegelberger G, Capstick M, Manser M, Müller M, Schmid CD, Schürmann D, Struchen B, Kuster N.

Bioelectromagnetics. 2016 Apr;37(3):183-189. doi: 10.1002/bem.21963. Epub 2016 Mar 15.

PMID:
26991812
34.

The dynamic subcellular localization of ERK: mechanisms of translocation and role in various organelles.

Wainstein E, Seger R.

Curr Opin Cell Biol. 2016 Apr;39:15-20. doi: 10.1016/j.ceb.2016.01.007. Epub 2016 Jan 29. Review.

PMID:
26827288
35.

Retraction notice to "Regulation of p53: Intricate loops and delicate balances" [Biochem. Pharmacol. 64 (2002) 865-871].

Oren M, Damalas A, Gottlieb T, Michael D, Taplick J, Martinez Leal JF, Maya R, Moas M, Seger R, Taya Y, Ben-Ze'ev A.

Biochem Pharmacol. 2015 Aug 15;96(4):369. doi: 10.1016/j.bcp.2015.07.001. No abstract available.

PMID:
26465018
36.

Mitotic Golgi translocation of ERK1c is mediated by a PI4KIIIβ-14-3-3γ shuttling complex.

Wortzel I, Hanoch T, Porat Z, Hausser A, Seger R.

J Cell Sci. 2015 Nov 15;128(22):4083-95. doi: 10.1242/jcs.170910. Epub 2015 Oct 12.

37.

Role of PI4K and PI3K-AKT in ERK1/2 activation by GnRH in the pituitary gonadotropes.

Bar-Lev TH, Harris D, Tomić M, Stojilkovic S, Blumenfeld Z, Brown P, Seger R, Naor Z.

Mol Cell Endocrinol. 2015 Nov 5;415:12-23. doi: 10.1016/j.mce.2015.07.029. Epub 2015 Aug 1.

38.

Successful Combination of Sequential Gene Therapy and Rescue Allo-HSCT in Two Children with X-CGD - Importance of Timing.

Siler U, Paruzynski A, Holtgreve-Grez H, Kuzmenko E, Koehl U, Renner ED, Alhan C, de Loosdrecht AA, Schwäble J, Pfluger T, Tchinda J, Schmugge M, Jauch A, Naundorf S, Kühlcke K, Notheis G, Güngor T, Kalle CV, Schmidt M, Grez M, Seger R, Reichenbach J.

Curr Gene Ther. 2015;15(4):416-27.

PMID:
25981636
39.

Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments.

Schevzov G, Kee AJ, Wang B, Sequeira VB, Hook J, Coombes JD, Lucas CA, Stehn JR, Musgrove EA, Cretu A, Assoian R, Fath T, Hanoch T, Seger R, Pleines I, Kile BT, Hardeman EC, Gunning PW.

Mol Biol Cell. 2015 Jul 1;26(13):2475-90. doi: 10.1091/mbc.E14-10-1453. Epub 2015 May 13.

40.

Membrane-permeable tastants amplify β2-adrenergic receptor signaling and delay receptor desensitization via intracellular inhibition of GRK2's kinase activity.

Malach E, Shaul ME, Peri I, Huang L, Spielman AI, Seger R, Naim M.

Biochim Biophys Acta. 2015 Jul;1850(7):1375-88. doi: 10.1016/j.bbagen.2015.03.015. Epub 2015 Apr 6.

PMID:
25857770
41.

The nuclear translocation of ERK1/2 as an anticancer target.

Plotnikov A, Flores K, Maik-Rachline G, Zehorai E, Kapri-Pardes E, Berti DA, Hanoch T, Besser MJ, Seger R.

Nat Commun. 2015 Mar 30;6:6685. doi: 10.1038/ncomms7685.

PMID:
25819065
42.

Dynamic distribution of ERK, p38 and JNK during the development of pancreatic ductal adenocarcinoma.

Amsterdam A, Shpigner L, Raanan C, Schreiber L, Melzer E, Seger R.

Acta Histochem. 2014 Oct;116(8):1434-42. doi: 10.1016/j.acthis.2014.09.007. Epub 2014 Oct 30.

PMID:
25440531
43.

Nuclear to cytoplasmic shuttling of ERK promotes differentiation of muscle stem/progenitor cells.

Michailovici I, Harrington HA, Azogui HH, Yahalom-Ronen Y, Plotnikov A, Ching S, Stumpf MP, Klein OD, Seger R, Tzahor E.

Development. 2014 Jul;141(13):2611-20. doi: 10.1242/dev.107078. Epub 2014 Jun 12.

44.

GM1-gangliosidosis in American black bears: clinical, pathological, biochemical and molecular genetic characterization.

Muthupalani S, Torres PA, Wang BC, Zeng BJ, Eaton S, Erdelyi I, Ducore R, Maganti R, Keating J, Perry BJ, Tseng FS, Waliszewski N, Pokras M, Causey R, Seger R, March P, Tidwell A, Pfannl R, Seyfried T, Kolodny EH, Alroy J.

Mol Genet Metab. 2014 Apr;111(4):513-21. doi: 10.1016/j.ymgme.2014.02.002. Epub 2014 Feb 13.

PMID:
24581871
45.

Modern management of primary T-cell immunodeficiencies.

Pachlopnik Schmid J, Güngör T, Seger R.

Pediatr Allergy Immunol. 2014 Jun;25(4):300-13. doi: 10.1111/pai.12179. Epub 2014 Jan 3. Review.

PMID:
24383740
46.

Compartmental genomics in living cells revealed by single-cell nanobiopsy.

Actis P, Maalouf MM, Kim HJ, Lohith A, Vilozny B, Seger RA, Pourmand N.

ACS Nano. 2014 Jan 28;8(1):546-53. doi: 10.1021/nn405097u. Epub 2013 Dec 4.

47.

Beta-like importins mediate the nuclear translocation of mitogen-activated protein kinases.

Zehorai E, Seger R.

Mol Cell Biol. 2014 Jan;34(2):259-70. doi: 10.1128/MCB.00799-13. Epub 2013 Nov 11. Erratum in: Mol Cell Biol. 2017 Jul 28;37(16):. Retraction in: Mol Cell Biol. 2018 May 15;38(11):.

48.

ERK as a model for systems biology of enzyme kinetics in cells.

Futran AS, Link AJ, Seger R, Shvartsman SY.

Curr Biol. 2013 Nov 4;23(21):R972-9. doi: 10.1016/j.cub.2013.09.033. Review.

49.

Stimulated nuclear import by β-like importins.

Flores K, Seger R.

F1000Prime Rep. 2013 Oct 1;5:41. doi: 10.12703/P5-41. Review.

50.

Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study.

Güngör T, Teira P, Slatter M, Stussi G, Stepensky P, Moshous D, Vermont C, Ahmad I, Shaw PJ, Telles da Cunha JM, Schlegel PG, Hough R, Fasth A, Kentouche K, Gruhn B, Fernandes JF, Lachance S, Bredius R, Resnick IB, Belohradsky BH, Gennery A, Fischer A, Gaspar HB, Schanz U, Seger R, Rentsch K, Veys P, Haddad E, Albert MH, Hassan M; Inborn Errors Working Party of the European Society for Blood and Marrow Transplantation.

Lancet. 2014 Feb 1;383(9915):436-48. doi: 10.1016/S0140-6736(13)62069-3. Epub 2013 Oct 23.

PMID:
24161820

Supplemental Content

Support Center