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Items: 1 to 50 of 357

1.

Ni-Catalyzed α-Selective C-H Borylations of Naphthalene-Based Aromatic Compounds.

Kamei T, Nishino S, Yagi A, Segawa Y, Shimada T.

J Org Chem. 2019 Oct 18. doi: 10.1021/acs.joc.9b02333. [Epub ahead of print]

PMID:
31594300
2.

Dietary capsaicin-mediated attenuation of hypertension in a rat model of renovascular hypertension.

Segawa Y, Hashimoto H, Maruyama S, Shintani M, Ohno H, Nakai Y, Osera T, Kurihara N.

Clin Exp Hypertens. 2019 Sep 13:1-8. doi: 10.1080/10641963.2019.1665676. [Epub ahead of print]

PMID:
31518162
3.

Topologically Unique Molecular Nanocarbons.

Segawa Y, Levine DR, Itami K.

Acc Chem Res. 2019 Oct 15;52(10):2760-2767. doi: 10.1021/acs.accounts.9b00402. Epub 2019 Sep 13.

PMID:
31517488
4.

Negatively Curved Warped Nanographene Self-Assembled on Metal Surfaces.

Urgel JI, Di Giovannantonio M, Segawa Y, Ruffieux P, Scott LT, Pignedoli CA, Itami K, Fasel R.

J Am Chem Soc. 2019 Aug 21;141(33):13158-13164. doi: 10.1021/jacs.9b05501. Epub 2019 Aug 5.

PMID:
31340123
5.

Topological molecular nanocarbons: All-benzene catenane and trefoil knot.

Segawa Y, Kuwayama M, Hijikata Y, Fushimi M, Nishihara T, Pirillo J, Shirasaki J, Kubota N, Itami K.

Science. 2019 Jul 19;365(6450):272-276. doi: 10.1126/science.aav5021.

PMID:
31320538
6.

Bi-allelic CSF1R Mutations Cause Skeletal Dysplasia of Dysosteosclerosis-Pyle Disease Spectrum and Degenerative Encephalopathy with Brain Malformation.

Guo L, Bertola DR, Takanohashi A, Saito A, Segawa Y, Yokota T, Ishibashi S, Nishida Y, Yamamoto GL, Franco JFDS, Honjo RS, Kim CA, Musso CM, Timmons M, Pizzino A, Taft RJ, Lajoie B, Knight MA, Fischbeck KH, Singleton AB, Ferreira CR, Wang Z, Yan L, Garbern JY, Simsek-Kiper PO, Ohashi H, Robey PG, Boyde A, Matsumoto N, Miyake N, Spranger J, Schiffmann R, Vanderver A, Nishimura G, Passos-Bueno MRDS, Simons C, Ishikawa K, Ikegawa S.

Am J Hum Genet. 2019 May 2;104(5):925-935. doi: 10.1016/j.ajhg.2019.03.004. Epub 2019 Apr 11.

PMID:
30982609
7.

Synthesis and structural features of thiophene-fused analogues of warped nanographene and quintuple helicene.

Lin HA, Kato K, Segawa Y, Scott LT, Itami K.

Chem Sci. 2018 Dec 19;10(8):2326-2330. doi: 10.1039/c8sc04470h. eCollection 2019 Feb 28.

8.

Polycyclic Arene Synthesis by Annulative π-Extension.

Ito H, Segawa Y, Murakami K, Itami K.

J Am Chem Soc. 2019 Jan 9;141(1):3-10. doi: 10.1021/jacs.8b09232. Epub 2018 Nov 13.

PMID:
30395456
9.

Tumor Sidedness and Enriched Gene Groups for Efficacy of First-line Cetuximab Treatment in Metastatic Colorectal Cancer.

Sunakawa Y, Mogushi K, Lenz HJ, Zhang W, Tsuji A, Takahashi T, Denda T, Shimada K, Kochi M, Nakamura M, Kotaka M, Segawa Y, Tanioka H, Negoro Y, Moran M, Astrow SH, Hsiang J, Stephens C, Fujii M, Ichikawa W.

Mol Cancer Ther. 2018 Dec;17(12):2788-2795. doi: 10.1158/1535-7163.MCT-18-0694. Epub 2018 Oct 1.

PMID:
30275242
10.

Anatomy of the Tarsal Canal and Sinus in Relation to the Subtalar Joint Capsule.

Yamaguchi R, Nimura A, Amaha K, Yamaguchi K, Segawa Y, Okawa A, Akita K.

Foot Ankle Int. 2018 Nov;39(11):1360-1369. doi: 10.1177/1071100718788038. Epub 2018 Jul 27.

PMID:
30052059
11.

Synthesis and Size-Dependent Properties of [12], [16], and [24]Carbon Nanobelts.

Povie G, Segawa Y, Nishihara T, Miyauchi Y, Itami K.

J Am Chem Soc. 2018 Aug 8;140(31):10054-10059. doi: 10.1021/jacs.8b06842. Epub 2018 Jul 26.

PMID:
30032597
12.

Synthesis and Structure of a Propeller-Shaped Polycyclic Aromatic Hydrocarbon Containing Seven-Membered Rings.

Kawai K, Kato K, Peng L, Segawa Y, Scott LT, Itami K.

Org Lett. 2018 Apr 6;20(7):1932-1935. doi: 10.1021/acs.orglett.8b00477. Epub 2018 Mar 21.

PMID:
29560728
13.

A Water-Soluble Warped Nanographene: Synthesis and Applications for Photoinduced Cell Death.

Lin HA, Sato Y, Segawa Y, Nishihara T, Sugimoto N, Scott LT, Higashiyama T, Itami K.

Angew Chem Int Ed Engl. 2018 Mar 5;57(11):2874-2878. doi: 10.1002/anie.201713387. Epub 2018 Feb 8.

PMID:
29380493
14.

A Quintuple [6]Helicene with a Corannulene Core as a C5 -Symmetric Propeller-Shaped π-System.

Kato K, Segawa Y, Scott LT, Itami K.

Angew Chem Int Ed Engl. 2018 Jan 26;57(5):1337-1341. doi: 10.1002/anie.201711985. Epub 2018 Jan 9.

PMID:
29280250
15.

Correction to: Multicenter phase II study of trastuzumab plus S-1 alone in elderly patients with HER2-positive advanced gastric cancer (JACCRO GC‑06).

Kimura Y, Fujii M, Masuishi T, Nishikawa K, Kunisaki C, Matsusaka S, Segawa Y, Nakamura M, Sasaki K, Nagao N, Hatachi Y, Yuasa Y, Asami S, Takeuchi M, Furukawa H, Nakajima T; JACCRO GC-06 Study Group.

Gastric Cancer. 2018 May;21(3):428. doi: 10.1007/s10120-017-0784-8.

PMID:
29234896
16.

CEA Response and Depth of Response (DpR) to Predict Clinical Outcomes of First-Line Cetuximab Treatment for Metastatic Colorectal Cancer.

Sunakawa Y, Tsuji A, Denda T, Segawa Y, Negoro Y, Shimada K, Kochi M, Nakamura M, Kotaka M, Tanioka H, Takagane A, Tani S, Yamaguchi T, Watanabe T, Takeuchi M, Fujii M, Ichikawa W.

Target Oncol. 2017 Dec;12(6):787-794. doi: 10.1007/s11523-017-0527-0.

PMID:
29064002
17.

Multicenter phase II study of trastuzumab plus S-1 alone in elderly patients with HER2-positive advanced gastric cancer (JACCRO GC-06).

Kimura Y, Fujii M, Masuishi T, Nishikawa K, Kunisaki C, Matsusaka S, Segawa Y, Nakamura M, Sasaki K, Nagao N, Hatachi Y, Yuasa Y, Asami S, Takeuchi M, Furukawa H, Nakajima T; JACCRO GC-06 Study Group.

Gastric Cancer. 2018 May;21(3):421-427. doi: 10.1007/s10120-017-0766-x. Epub 2017 Sep 21. Erratum in: Gastric Cancer. 2017 Dec 12;:.

18.

Laterally π-Extended Dithia[6]helicenes with Heptagons: Saddle-Helix Hybrid Molecules.

Fujikawa T, Segawa Y, Itami K.

J Org Chem. 2017 Aug 4;82(15):7745-7749. doi: 10.1021/acs.joc.7b01540. Epub 2017 Jul 12.

PMID:
28686025
19.

Synthesis, properties, and crystal structures of π-extended double [6]helicenes: contorted multi-dimensional stacking lattice.

Fujikawa T, Mitoma N, Wakamiya A, Saeki A, Segawa Y, Itami K.

Org Biomol Chem. 2017 May 31;15(21):4697-4703. doi: 10.1039/c7ob00987a.

PMID:
28516991
20.

Synthesis and properties of [8]-, [10]-, [12]-, and [16]cyclo-1,4-naphthylenes.

Okada K, Yagi A, Segawa Y, Itami K.

Chem Sci. 2017 Jan 1;8(1):661-667. doi: 10.1039/c6sc04048a. Epub 2016 Sep 12.

21.

Synthesis of a carbon nanobelt.

Povie G, Segawa Y, Nishihara T, Miyauchi Y, Itami K.

Science. 2017 Apr 14;356(6334):172-175. doi: 10.1126/science.aam8158.

PMID:
28408599
22.

Survey of Nitrate Ion Concentrations in Vegetables Cultivated in Plant Factories: Comparison with Open-Culture Vegetables.

Oka Y, Hirayama I, Yoshikawa M, Yokoyama T, Iida K, Iwakoshi K, Suzuki A, Yanagihara M, Segawa Y, Kukimoto S, Hamada H, Matsuzawa S, Tabata S, Sasamoto T.

Shokuhin Eiseigaku Zasshi. 2017;58(1):49-58. doi: 10.3358/shokueishi.58.49. Japanese.

23.

Prognostic Impact of Primary Tumor Location on Clinical Outcomes of Metastatic Colorectal Cancer Treated With Cetuximab Plus Oxaliplatin-Based Chemotherapy: A Subgroup Analysis of the JACCRO CC-05/06 Trials.

Sunakawa Y, Ichikawa W, Tsuji A, Denda T, Segawa Y, Negoro Y, Shimada K, Kochi M, Nakamura M, Kotaka M, Tanioka H, Takagane A, Tani S, Yamaguchi T, Watanabe T, Takeuchi M, Fujii M, Nakajima T.

Clin Colorectal Cancer. 2017 Sep;16(3):e171-e180. doi: 10.1016/j.clcc.2016.09.010. Epub 2016 Oct 6.

PMID:
27856123
24.

Synthesis, Structure, and Reactivity of a Cylinder-Shaped Cyclo[12]orthophenylene[6]ethynylene: Toward the Synthesis of Zigzag Carbon Nanobelts.

Matsui K, Fushimi M, Segawa Y, Itami K.

Org Lett. 2016 Oct 21;18(20):5352-5355. doi: 10.1021/acs.orglett.6b02702. Epub 2016 Oct 10.

PMID:
27718578
25.

Thiophene-Fused π-Systems from Diarylacetylenes and Elemental Sulfur.

Meng L, Fujikawa T, Kuwayama M, Segawa Y, Itami K.

J Am Chem Soc. 2016 Aug 17;138(32):10351-5. doi: 10.1021/jacs.6b06486. Epub 2016 Aug 8.

PMID:
27501373
26.

Corannulene-Helicene Hybrids: Chiral π-Systems Comprising Both Bowl and Helical Motifs.

Fujikawa T, Preda DV, Segawa Y, Itami K, Scott LT.

Org Lett. 2016 Aug 19;18(16):3992-5. doi: 10.1021/acs.orglett.6b01801. Epub 2016 Aug 4.

PMID:
27490184
27.

Single Versus Combined Procedures for Severely Involved Legg-Calvé-Perthes Disease.

Kamegaya M, Morita M, Saisu T, Kakizaki J, Oikawa Y, Segawa Y.

J Pediatr Orthop. 2018 Jul;38(6):312-319. doi: 10.1097/BPO.0000000000000840.

PMID:
27442215
28.

Long-term combination chemotherapy using eribulin and trastuzumab for three patients with human epidermal growth factor receptor 2-positive metastatic breast cancer.

Saeki T, Araki K, Shimada K, Shigekawa T, Nakayama H, Segawa Y, Mukai H.

Int Cancer Conf J. 2016 Jun 21;5(4):178-182. doi: 10.1007/s13691-016-0253-y. eCollection 2016 Oct.

29.

Combined assessment of EGFR-related molecules to predict outcome of 1st-line cetuximab-containing chemotherapy for metastatic colorectal cancer.

Sunakawa Y, Yang D, Moran M, Astrow SH, Tsuji A, Stephens C, Zhang W, Cao S, Takahashi T, Denda T, Shimada K, Kochi M, Nakamura M, Kotaka M, Segawa Y, Masuishi T, Takeuchi M, Fujii M, Nakajima T, Ichikawa W, Lenz HJ.

Cancer Biol Ther. 2016 Jul 2;17(7):751-9. doi: 10.1080/15384047.2016.1178426. Epub 2016 Apr 22.

30.

Induction of metallothionein isoforms by copper diethyldithiocarbamate in cultured vascular endothelial cells.

Fujie T, Segawa Y, Yoshida E, Kimura T, Fujiwara Y, Yamamoto C, Satoh M, Naka H, Kaji T.

J Toxicol Sci. 2016 Apr;41(2):225-32. doi: 10.2131/jts.41.225.

31.

Zinc diethyldithiocarbamate as an inducer of metallothionein in cultured vascular endothelial cells.

Fujie T, Segawa Y, Uehara A, Nakamura T, Kimura T, Yoshida E, Yamamoto C, Uchiyama M, Naka H, Kaji T.

J Toxicol Sci. 2016 Apr;41(2):217-24. doi: 10.2131/jts.41.217.

32.

A Theoretical Study on the Strain Energy of Carbon Nanobelts.

Segawa Y, Yagi A, Ito H, Itami K.

Org Lett. 2016 Mar 18;18(6):1430-3. doi: 10.1021/acs.orglett.6b00365. Epub 2016 Mar 8.

PMID:
26953497
33.

Synthesis and Structural Features of Quadruple Helicenes: Highly Distorted π Systems Enabled by Accumulation of Helical Repulsions.

Fujikawa T, Segawa Y, Itami K.

J Am Chem Soc. 2016 Mar 16;138(10):3587-95. doi: 10.1021/jacs.6b01303. Epub 2016 Mar 4.

PMID:
26918641
34.

Design and Synthesis of Carbon Nanotube Segments.

Segawa Y, Yagi A, Matsui K, Itami K.

Angew Chem Int Ed Engl. 2016 Apr 18;55(17):5136-58. doi: 10.1002/anie.201508384. Epub 2016 Feb 18. Review.

PMID:
26890967
35.

Pyridylidene ligand facilitates gold-catalyzed oxidative C-H arylation of heterocycles.

Hata K, Ito H, Segawa Y, Itami K.

Beilstein J Org Chem. 2015 Dec 28;11:2737-46. doi: 10.3762/bjoc.11.295. eCollection 2015.

36.

Synthesis of open-shell ladder π-systems by catalytic C-H annulation of diarylacetylenes.

Maekawa T, Ueno H, Segawa Y, Haley MM, Itami K.

Chem Sci. 2016 Jan 1;7(1):650-654. doi: 10.1039/c5sc03391h. Epub 2015 Oct 22.

37.

Subgroup analyses of the safety and efficacy of ramucirumab in Japanese and Western patients in RAINBOW: a randomized clinical trial in second-line treatment of gastric cancer.

Shitara K, Muro K, Shimada Y, Hironaka S, Sugimoto N, Komatsu Y, Nishina T, Yamaguchi K, Segawa Y, Omuro Y, Tamura T, Doi T, Yukisawa S, Yasui H, Nagashima F, Gotoh M, Esaki T, Emig M, Chandrawansa K, Liepa AM, Wilke H, Ichimiya Y, Ohtsu A.

Gastric Cancer. 2016 Jul;19(3):927-38. doi: 10.1007/s10120-015-0559-z. Epub 2015 Oct 28.

PMID:
26510663
38.

Curved Oligophenylenes as Donors in Shape-Persistent Donor-Acceptor Macrocycles with Solvatofluorochromic Properties.

Kuwabara T, Orii J, Segawa Y, Itami K.

Angew Chem Int Ed Engl. 2015 Aug 10;54(33):9646-9. doi: 10.1002/anie.201503397. Epub 2015 Jul 3.

PMID:
26140706
39.

Synthesis, Properties, and Packing Structures of Corannulene-Based π-Systems Containing Heptagons.

Kato K, Segawa Y, Scott LT, Itami K.

Chem Asian J. 2015 Aug;10(8):1635-9. doi: 10.1002/asia.201500560. Epub 2015 Jun 25.

PMID:
26062779
40.

Synthesis, Structures, and Properties of π-Extended Double Helicene: A Combination of Planar and Nonplanar π-Systems.

Fujikawa T, Segawa Y, Itami K.

J Am Chem Soc. 2015 Jun 24;137(24):7763-8. doi: 10.1021/jacs.5b03118. Epub 2015 Jun 11.

PMID:
26028308
41.

para-C-H Borylation of Benzene Derivatives by a Bulky Iridium Catalyst.

Saito Y, Segawa Y, Itami K.

J Am Chem Soc. 2015 Apr 22;137(15):5193-8. doi: 10.1021/jacs.5b02052. Epub 2015 Apr 10.

PMID:
25860511
42.

Induction of CD44 variant 9-expressing cancer stem cells might attenuate the efficacy of chemoradioselection and Worsens the prognosis of patients with advanced head and neck cancer.

Aso T, Matsuo M, Kiyohara H, Taguchi K, Rikimaru F, Shimokawa M, Segawa Y, Higaki Y, Umeno H, Nakashima T, Masuda M.

PLoS One. 2015 Mar 9;10(3):e0116596. doi: 10.1371/journal.pone.0116596. eCollection 2015.

43.

Synthesis and characterization of hexaarylbenzenes with five or six different substituents enabled by programmed synthesis.

Suzuki S, Segawa Y, Itami K, Yamaguchi J.

Nat Chem. 2015 Mar;7(3):227-33. doi: 10.1038/nchem.2174. Epub 2015 Jan 26.

PMID:
25698332
44.

Cycloparaphenylene-based ionic donor-acceptor supramolecule: isolation and characterization of Li⁺@C60⊂[10]CPP.

Ueno H, Nishihara T, Segawa Y, Itami K.

Angew Chem Int Ed Engl. 2015 Mar 16;54(12):3707-11. doi: 10.1002/anie.201500544. Epub 2015 Feb 18.

PMID:
25693784
45.
46.

A phase II study of cisplatin plus S-1 with concurrent thoracic radiotherapy for locally advanced non-small-cell lung cancer: the Okayama Lung Cancer Study Group Trial 0501.

Nogami N, Takigawa N, Hotta K, Segawa Y, Kato Y, Kozuki T, Oze I, Kishino D, Aoe K, Ueoka H, Kuyama S, Harita S, Okada T, Hosokawa S, Inoue K, Gemba K, Shibayama T, Tabata M, Takemoto M, Kanazawa S, Tanimoto M, Kiura K.

Lung Cancer. 2015 Feb;87(2):141-7. doi: 10.1016/j.lungcan.2014.11.001. Epub 2014 Nov 8.

PMID:
25534129
47.

Thiophene-based, radial π-conjugation: synthesis, structure, and photophysical properties of cyclo-1,4-phenylene-2',5'-thienylenes.

Ito H, Mitamura Y, Segawa Y, Itami K.

Angew Chem Int Ed Engl. 2015 Jan 2;54(1):159-63. doi: 10.1002/anie.201409389. Epub 2014 Nov 20.

PMID:
25413894
48.

All-benzene carbon nanocages: size-selective synthesis, photophysical properties, and crystal structure.

Matsui K, Segawa Y, Itami K.

J Am Chem Soc. 2014 Nov 19;136(46):16452-8. doi: 10.1021/ja509880v. Epub 2014 Nov 7.

PMID:
25361385
49.

Synthesis of extended π-systems through C-H activation.

Segawa Y, Maekawa T, Itami K.

Angew Chem Int Ed Engl. 2015 Jan 2;54(1):66-81. doi: 10.1002/anie.201403729. Epub 2014 Sep 26.

PMID:
25255741
50.

Divergent synthesis of bioactive resorcinols isolated from the fruiting bodies of Hericium erinaceum: total syntheses of hericenones A, B, and I, hericenols B-D, and erinacerins A and B.

Kobayashi S, Tamanoi H, Hasegawa Y, Segawa Y, Masuyama A.

J Org Chem. 2014 Jun 6;79(11):5227-38. doi: 10.1021/jo500795z. Epub 2014 May 23.

PMID:
24833262

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