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Germline BRCA-associated Endometrial Carcinoma is a Distinct Clinicopathologic Entity.

de Jonge MM, Ritterhouse LL, de Kroon CD, Vreeswijk MPG, Segal JP, Puranik R, Study H, Hollema H, Rookus MA, van Asperen CJ, Van Leeuwen FE, Smit VTHBM, Howitt BE, Bosse T.

Clin Cancer Res. 2019 Sep 6. pii: clincanres.0848.2019. doi: 10.1158/1078-0432.CCR-19-0848. [Epub ahead of print]


Polyp detection rate: does length matter?

Segal JP, Kanagasundaram C, Mills P, Bassett P, Greenfield SM.

Frontline Gastroenterol. 2019 Apr;10(2):107-112. doi: 10.1136/flgastro-2017-100945. Epub 2018 Jul 24.


Quantitative next-generation sequencing-based analysis indicates progressive accumulation of microsatellite instability between atypical hyperplasia/endometrial intraepithelial neoplasia and paired endometrioid endometrial carcinoma.

Chapel DB, Patil SA, Plagov A, Puranik R, Mendybaeva A, Steinhardt G, Wanjari P, Lastra RR, Kadri S, Segal JP, Ritterhouse LL.

Mod Pathol. 2019 Oct;32(10):1508-1520. doi: 10.1038/s41379-019-0298-5. Epub 2019 Jun 11.


High NPM1 mutant allele burden at diagnosis correlates with minimal residual disease at first remission in de novo acute myeloid leukemia.

Patel SS, Pinkus GS, Ritterhouse LL, Segal JP, Dal Cin P, Restrepo T, Harris MH, Stone RM, Hasserjian RP, Weinberg OK.

Am J Hematol. 2019 Aug;94(8):921-928. doi: 10.1002/ajh.25544. Epub 2019 Jun 17.


The gut virome: the 'missing link' between gut bacteria and host immunity?

Mukhopadhya I, Segal JP, Carding SR, Hart AL, Hold GL.

Therap Adv Gastroenterol. 2019 Mar 25;12:1756284819836620. doi: 10.1177/1756284819836620. eCollection 2019. Review.


γδ T Cells Modulate Myeloid Cell Recruitment but Not Pain During Peripheral Inflammation.

Petrović J, Silva JR, Bannerman CA, Segal JP, Marshall AS, Haird CM, Gilron I, Ghasemlou N.

Front Immunol. 2019 Mar 18;10:473. doi: 10.3389/fimmu.2019.00473. eCollection 2019.


Dihydropyrimidine dehydrogenase deficiency as a cause of fatal 5-Fluorouracil toxicity.

Fidai SS, Sharma AE, Johnson DN, Segal JP, Lastra RR.

Autops Case Rep. 2018 Nov 30;8(4):e2018049. doi: 10.4322/acr.2018.049. eCollection 2018 Oct-Dec.


The Renew® anal insert for passive faecal incontinence: a retrospective audit of our use of a novel device.

Leo CA, Thomas GP, Hodgkinson JD, Segal JP, Maeda Y, Murphy J, Vaizey CJ.

Colorectal Dis. 2019 Jun;21(6):684-688. doi: 10.1111/codi.14587. Epub 2019 Mar 12.


The application of omics techniques to understand the role of the gut microbiota in inflammatory bowel disease.

Segal JP, Mullish BH, Quraishi MN, Acharjee A, Williams HRT, Iqbal T, Hart AL, Marchesi JR.

Therap Adv Gastroenterol. 2019 Jan 24;12:1756284818822250. doi: 10.1177/1756284818822250. eCollection 2019. Review.


Autophagy Inhibition to Augment mTOR Inhibition: a Phase I/II Trial of Everolimus and Hydroxychloroquine in Patients with Previously Treated Renal Cell Carcinoma.

Haas NB, Appleman LJ, Stein M, Redlinger M, Wilks M, Xu X, Onorati A, Kalavacharla A, Kim T, Zhen CJ, Kadri S, Segal JP, Gimotty PA, Davis LE, Amaravadi RK.

Clin Cancer Res. 2019 Apr 1;25(7):2080-2087. doi: 10.1158/1078-0432.CCR-18-2204. Epub 2019 Jan 11.


Current Practices in Ileal Pouch Surveillance for Patients With Ulcerative Colitis: A Multinational, Retrospective Cohort Study.

Samaan MA, Forsyth K, Segal JP, De Jong D, Vleugels JLA, Elkady S, Kabir M, Campbell S, Kok K, Armstrong DG, Penez L, Arenaza AP, Seward E, Vega R, Mehta S, Rahman F, McCartney S, Bloom S, Patel K, Pollok R, Westcott E, Darakhshan A, Williams A, Koumoutsos I, Ray S, Mawdsley J, Anderson S, Sanderson JD, Dekker E, D'Haens GR, Hart A, Irving PM.

J Crohns Colitis. 2019 May 27;13(6):735-743. doi: 10.1093/ecco-jcc/jjy225.


Biological therapy for the treatment of prepouch ileitis: a retrospective observational study from three centers.

Segal JP, Rottoli M, Felwick RK, Worley GH, McLaughlin SD, Vallicelli C, Bassett P, Faiz OD, Hart AL, Clark SK.

Clin Exp Gastroenterol. 2018 Dec 11;11:461-465. doi: 10.2147/CEG.S179418. eCollection 2018.


Clinicopathologic and Molecular Features of Metastatic Follicular Thyroid Carcinoma in Patients Presenting With a Thyroid Nodule Versus a Distant Metastasis.

Cracolici V, Kadri S, Ritterhouse LL, Segal JP, Wanjari P, Cipriani NA.

Am J Surg Pathol. 2019 Apr;43(4):514-522. doi: 10.1097/PAS.0000000000001208.


Author Correction: Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis.

Pitroda SP, Khodarev NN, Huang L, Uppal A, Wightman SC, Ganai S, Joseph N, Pitt J, Brown M, Forde M, Mangold K, Xue L, Weber C, Segal JP, Kadri S, Stack ME, Khan S, Paty P, Kaul K, Andrade J, White KP, Talamonti M, Posner MC, Hellman S, Weichselbaum RR.

Nat Commun. 2018 Nov 13;9(1):4827. doi: 10.1038/s41467-018-07303-w.


insiM: in silico Mutator Software for Bioinformatics Pipeline Validation of Clinical Next-Generation Sequencing Assays.

Patil SA, Mujacic I, Ritterhouse LL, Segal JP, Kadri S.

J Mol Diagn. 2019 Jan;21(1):19-26. doi: 10.1016/j.jmoldx.2018.08.001. Epub 2018 Sep 29.


Long term outcomes of initial infliximab therapy for inflammatory pouch pathology: a multi-Centre retrospective study.

Segal JP, Penez L, Mohsen Elkady S, Worley GHT, McLaughlin SD, Mullish BH, Quraishi MN, Ding NS, Glyn T, Kandiah K, Samaan MA, Irving PM, Faiz OD, Clark SK, Hart AL.

Scand J Gastroenterol. 2018 Sep;53(9):1051-1058. doi: 10.1080/00365521.2018.1496271. Epub 2018 Sep 29.


Introduction to the joint British Society of Gastroenterology (BSG) and Healthcare Infection Society (HIS) faecal microbiota transplant guidelines.

Mullish BH, Quraishi MN, Segal JP, Williams HRT, Goldenberg SD.

J Hosp Infect. 2018 Oct;100(2):130-132. doi: 10.1016/j.jhin.2018.07.028. Epub 2018 Sep 18. No abstract available.


Acceptability, effectiveness and safety of a Renew® anal insert in patients who have undergone restorative proctocolectomy with ileal pouch-anal anastomosis.

Segal JP, Leo CA, Hodgkinson JD, Cavazzoni E, Bradshaw E, Lung PFC, Ilangovan R, Vaizey CJ, Faiz OD, Hart AL, Clark SK.

Colorectal Dis. 2019 Jan;21(1):73-78. doi: 10.1111/codi.14422. Epub 2018 Oct 8.


Cribriform-Morular Variant of Papillary Thyroid Carcinoma With Poorly Differentiated Features: A Case Report With Immunohistochemical and Molecular Genetic Analysis.

Corean J, Furtado LV, Kadri S, Segal JP, Emerson LL.

Int J Surg Pathol. 2019 May;27(3):294-304. doi: 10.1177/1066896918796946. Epub 2018 Sep 3.


The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridium difficile infection and other potential indications: joint British Society of Gastroenterology (BSG) and Healthcare Infection Society (HIS) guidelines.

Mullish BH, Quraishi MN, Segal JP, McCune VL, Baxter M, Marsden GL, Moore D, Colville A, Bhala N, Iqbal TH, Settle C, Kontkowski G, Hart AL, Hawkey PM, Williams HR, Goldenberg SD.

J Hosp Infect. 2018 Sep;100 Suppl 1:S1-S31. doi: 10.1016/j.jhin.2018.07.037. No abstract available.


Human Organoids Share Structural and Genetic Features with Primary Pancreatic Adenocarcinoma Tumors.

Romero-Calvo I, Weber CR, Ray M, Brown M, Kirby K, Nandi RK, Long TM, Sparrow SM, Ugolkov A, Qiang W, Zhang Y, Brunetti T, Kindler H, Segal JP, Rzhetsky A, Mazar AP, Buschmann MM, Weichselbaum R, Roggin K, White KP.

Mol Cancer Res. 2019 Jan;17(1):70-83. doi: 10.1158/1541-7786.MCR-18-0531. Epub 2018 Aug 31.


The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridium difficile infection and other potential indications: joint British Society of Gastroenterology (BSG) and Healthcare Infection Society (HIS) guidelines.

Mullish BH, Quraishi MN, Segal JP, McCune VL, Baxter M, Marsden GL, Moore DJ, Colville A, Bhala N, Iqbal TH, Settle C, Kontkowski G, Hart AL, Hawkey PM, Goldenberg SD, Williams HRT.

Gut. 2018 Nov;67(11):1920-1941. doi: 10.1136/gutjnl-2018-316818. Epub 2018 Aug 28.


Management of early pouch-related septic complications in ulcerative colitis: a systematic review.

Worley GHT, Segal JP, Warusavitarne J, Clark SK, Faiz OD.

Colorectal Dis. 2018 Aug;20(8):O181-O189. doi: 10.1111/codi.14266. Epub 2018 Jun 12.


Does the Internet promote the unregulated use of fecal microbiota transplantation: a potential public health issue?

Segal JP, Abbasi F, Kanagasundaram C, Hart A.

Clin Exp Gastroenterol. 2018 May 1;11:179-183. doi: 10.2147/CEG.S159609. eCollection 2018.


Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis.

Pitroda SP, Khodarev NN, Huang L, Uppal A, Wightman SC, Ganai S, Joseph N, Pitt J, Brown M, Forde M, Mangold K, Xue L, Weber C, Segal JP, Kadri S, Stack ME, Khan S, Paty P, Kaul K, Andrade J, White KP, Talamonti M, Posner MC, Hellman S, Weichselbaum RR.

Nat Commun. 2018 May 4;9(1):1793. doi: 10.1038/s41467-018-04278-6. Erratum in: Nat Commun. 2018 Nov 13;9(1):4827.


System for Informatics in the Molecular Pathology Laboratory: An Open-Source End-to-End Solution for Next-Generation Sequencing Clinical Data Management.

Kang W, Kadri S, Puranik R, Wurst MN, Patil SA, Mujacic I, Benhamed S, Niu N, Zhen CJ, Ameti B, Long BC, Galbo F, Montes D, Iracheta C, Gamboa VL, Lopez D, Yourshaw M, Lawrence CA, Aisner DL, Fitzpatrick C, McNerney ME, Wang YL, Andrade J, Volchenboum SL, Furtado LV, Ritterhouse LL, Segal JP.

J Mol Diagn. 2018 Jul;20(4):522-532. doi: 10.1016/j.jmoldx.2018.03.008. Epub 2018 Apr 24.


Long-term follow-up of the use of maintenance antibiotic therapy for chronic antibiotic-dependent pouchitis.

Segal JP, Poo SX, McLaughlin SD, Faiz OD, Clark SK, Hart AL.

Frontline Gastroenterol. 2018 Apr;9(2):154-158. doi: 10.1136/flgastro-2017-100913. Epub 2018 Jan 31.


Noninvasive Follicular Thyroid Neoplasms With Papillary-like Nuclear Features Are Genetically and Biologically Similar to Adenomatous Nodules and Distinct From Papillary Thyroid Carcinomas With Extensive Follicular Growth.

Johnson DN, Furtado LV, Long BC, Zhen CJ, Wurst M, Mujacic I, Kadri S, Segal JP, Antic T, Cipriani NA.

Arch Pathol Lab Med. 2018 Jul;142(7):838-850. doi: 10.5858/arpa.2017-0118-OA. Epub 2018 Mar 27.


Biofeedback in patients with ileoanal pouch dysfunction: a specialist centre experience.

Segal JP, Chan H, Collins B, Faiz OD, Clark SK, Hart AL.

Scand J Gastroenterol. 2018 Jun;53(6):665-669. doi: 10.1080/00365521.2018.1454508. Epub 2018 Mar 26.


Chronobiological regulation of psychosocial and physiological outcomes in multiple sclerosis.

De Somma E, Jain RW, Poon KWC, Tresidder KA, Segal JP, Ghasemlou N.

Neurosci Biobehav Rev. 2018 May;88:73-83. doi: 10.1016/j.neubiorev.2018.03.011. Epub 2018 Mar 13. Review.


Incidence and Long-term Implications of Prepouch Ileitis: An Observational Study.

Segal JP, McLaughlin SD, Faiz OD, Hart AL, Clark SK.

Dis Colon Rectum. 2018 Apr;61(4):472-475. doi: 10.1097/DCR.0000000000000978.


Twenty years of biological therapy in an patient with IBD.

Mak WY, Segal JP, Hart A.

BMJ Case Rep. 2018 Jan 23;2018. pii: bcr-2017-221994. doi: 10.1136/bcr-2017-221994.


Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies.

Drazer MW, Kadri S, Sukhanova M, Patil SA, West AH, Feurstein S, Calderon DA, Jones MF, Weipert CM, Daugherty CK, Ceballos-López AA, Raca G, Lingen MW, Li Z, Segal JP, Churpek JE, Godley LA.

Blood Adv. 2018 Jan 23;2(2):146-150. doi: 10.1182/bloodadvances.2017013037.


Clonal evolution underlying leukemia progression and Richter transformation in patients with ibrutinib-relapsed CLL.

Kadri S, Lee J, Fitzpatrick C, Galanina N, Sukhanova M, Venkataraman G, Sharma S, Long B, Petras K, Theissen M, Ming M, Kobzev Y, Kang W, Guo A, Wang W, Niu N, Weiner H, Thirman M, Stock W, Smith SM, Nabhan C, Segal JP, Lu P, Wang YL.

Blood Adv. 2017 May 2;1(12):715-727. doi: 10.1182/bloodadvances.2016003632. eCollection 2017 May 9.


Feasibility of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration Cytology Specimens for Next Generation Sequencing in Non-small-cell Lung Cancer.

Stoy SP, Segal JP, Mueller J, Furtado LV, Vokes EE, Patel JD, Murgu S.

Clin Lung Cancer. 2018 May;19(3):230-238.e2. doi: 10.1016/j.cllc.2017.11.010. Epub 2017 Dec 5.


Systematic review: ileoanal pouch microbiota in health and disease.

Segal JP, Oke S, Hold GL, Clark SK, Faiz OD, Hart AL.

Aliment Pharmacol Ther. 2018 Feb;47(4):466-477. doi: 10.1111/apt.14454. Epub 2017 Dec 5.


A Systematic Review: The Management and Outcomes of Ileal Pouch Strictures.

Segal JP, Adegbola SO, Worley GHT, Sahnan K, Tozer P, Lung PFC, Faiz OD, Clark SK, Hart AL.

J Crohns Colitis. 2018 Feb 28;12(3):369-375. doi: 10.1093/ecco-jcc/jjx151. Review.


Circadian control of pain and neuroinflammation.

Segal JP, Tresidder KA, Bhatt C, Gilron I, Ghasemlou N.

J Neurosci Res. 2018 Jun;96(6):1002-1020. doi: 10.1002/jnr.24150. Epub 2017 Sep 2. Review.


Synchronous and Metastatic Papillary and Follicular Thyroid Carcinomas with Unique Molecular Signatures.

Cracolici V, Mujacic I, Kadri S, Alikhan M, Niu N, Segal JP, Rosen LE, Sarne DH, Morgan A, Desouky S, Cipriani NA.

Endocr Pathol. 2018 Mar;29(1):9-14. doi: 10.1007/s12022-017-9491-6.


Risk factors, prevalence, and site concordance of human papillomavirus in high-risk Greek men.

Tsikis S, Hoefer L, Bethimoutis G, Nicolaidou E, Paparizos V, Antoniou C, Chardalias L, Stavropoulos GE, Sharma S, Long BC, Mujacic I, Kadri S, Segal JP, Furtado LV, Schneider J, Charnot-Katsikas A.

Eur J Cancer Prev. 2018 Sep;27(5):514-520. doi: 10.1097/CEJ.0000000000000366.


Systematic review with meta-analysis: the management of chronic refractory pouchitis with an evidence-based treatment algorithm.

Segal JP, Ding NS, Worley G, Mclaughlin S, Preston S, Faiz OD, Clark SK, Hart AL.

Aliment Pharmacol Ther. 2017 Mar;45(5):581-592. doi: 10.1111/apt.13905. Epub 2016 Dec 23. Review. Erratum in: Aliment Pharmacol Ther. 2018 Mar;47(6):864.


High prevalence of MiTF staining in undifferentiated pleomorphic sarcoma: caution in the use of melanocytic markers in sarcoma.

Choy B, Hyjek E, Montag AG, Pytel P, Haydon R, Luu HH, Zhen CJ, Long BC, Kadri S, Segal JP, Furtado LV, Cipriani NA.

Histopathology. 2017 Apr;70(5):734-745. doi: 10.1111/his.13139. Epub 2017 Feb 1.


Diagnostic evaluation of RNA sequencing for the detection of genetic abnormalities associated with Ph-like acute lymphoblastic leukemia (ALL).

Yap KL, Furtado LV, Kiyotani K, Curran E, Stock W, McNeer JL, Kadri S, Segal JP, Nakamura Y, Le Beau MM, Gurbuxani S, Raca G.

Leuk Lymphoma. 2017 Apr;58(4):950-958. doi: 10.1080/10428194.2016.1219902. Epub 2016 Nov 17.


Clinical Validation of a Next-Generation Sequencing Genomic Oncology Panel via Cross-Platform Benchmarking against Established Amplicon Sequencing Assays.

Kadri S, Long BC, Mujacic I, Zhen CJ, Wurst MN, Sharma S, McDonald N, Niu N, Benhamed S, Tuteja JH, Seiwert TY, White KP, McNerney ME, Fitzpatrick C, Wang YL, Furtado LV, Segal JP.

J Mol Diagn. 2017 Jan;19(1):43-56. doi: 10.1016/j.jmoldx.2016.07.012. Epub 2016 Nov 9.


Identification of a structurally novel BTK mutation that drives ibrutinib resistance in CLL.

Sharma S, Galanina N, Guo A, Lee J, Kadri S, Van Slambrouck C, Long B, Wang W, Ming M, Furtado LV, Segal JP, Stock W, Venkataraman G, Tang WJ, Lu P, Wang YL.

Oncotarget. 2016 Oct 18;7(42):68833-68841. doi: 10.18632/oncotarget.11932.


Identifying Inherited and Acquired Genetic Factors Involved in Poor Stem Cell Mobilization and Donor-Derived Malignancy.

Rojek K, Nickels E, Neistadt B, Marquez R, Wickrema A, Artz A, van Besien K, Larson RA, Lee MK, Segal JP, King MC, Walsh T, Shimamura A, Keel SB, Churpek JE, Godley LA.

Biol Blood Marrow Transplant. 2016 Nov;22(11):2100-2103. doi: 10.1016/j.bbmt.2016.08.002. Epub 2016 Aug 4.


Next-Generation Proficiency Testing.

Segal JP.

J Mol Diagn. 2016 Jul;18(4):469-70. doi: 10.1016/j.jmoldx.2016.05.001. Epub 2016 May 25.


Unclassified renal cell carcinoma with tubulopapillary architecture, clear cell phenotype, and chromosome 8 monosomy: a new kid on the block.

Lan TT, Keller-Ramey J, Fitzpatrick C, Kadri S, Taxy JB, Segal JP, Furtado LV, Antic T.

Virchows Arch. 2016 Jul;469(1):81-91. doi: 10.1007/s00428-016-1952-7. Epub 2016 May 12.


Polyglucosan bodies in intramuscular nerve branches are a poor predictor of GBE1 mutation and adult polyglucosan body disease.

Furtado LV, Kadri S, Wurst MN, Long BC, Segal JP, Pytel P.

Muscle Nerve. 2016 Mar;53(3):473-5. doi: 10.1002/mus.25017.


Amplicon Indel Hunter Is a Novel Bioinformatics Tool to Detect Large Somatic Insertion/Deletion Mutations in Amplicon-Based Next-Generation Sequencing Data.

Kadri S, Zhen CJ, Wurst MN, Long BC, Jiang ZF, Wang YL, Furtado LV, Segal JP.

J Mol Diagn. 2015 Nov;17(6):635-43. doi: 10.1016/j.jmoldx.2015.06.005. Epub 2015 Aug 28. Erratum in: J Mol Diagn. 2017 May;19(3):485.


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