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Items: 1 to 50 of 141

1.

The landscape of myeloid and astrocyte phenotypes in acute multiple sclerosis lesions.

Park C, Ponath G, Levine-Ritterman M, Bull E, Swanson EC, De Jager PL, Segal BM, Pitt D.

Acta Neuropathol Commun. 2019 Aug 12;7(1):130. doi: 10.1186/s40478-019-0779-2.

2.

Multiple sclerosis relapse risk in the postoperative period: Effects of invasive surgery and anesthesia.

De Lott LB, Zerafa S, Shedden K, Dunietz GL, Earley M, Segal BM, Braley TJ.

Mult Scler. 2019 Jun 25:1352458519860304. doi: 10.1177/1352458519860304. [Epub ahead of print]

PMID:
31237825
3.

Clinical trials in multiple sclerosis: potential future trial designs.

Manouchehri N, Zhang Y, Salter A, Hussain RZ, Hartung HP, Hemmer B, Linker R, Segal BM, Cutter G, Stüve O.

Ther Adv Neurol Disord. 2019 May 13;12:1756286419847095. doi: 10.1177/1756286419847095. eCollection 2019. Review.

4.

MAdCAM-1-Mediated Intestinal Lymphocyte Homing Is Critical for the Development of Active Experimental Autoimmune Encephalomyelitis.

Kuhbandner K, Hammer A, Haase S, Terbrack E, Hoffmann A, Schippers A, Wagner N, Hussain RZ, Miller-Little WA, Koh AY, Stoolman JS, Segal BM, Linker RA, Stüve O.

Front Immunol. 2019 Apr 26;10:903. doi: 10.3389/fimmu.2019.00903. eCollection 2019.

5.

Treatment of neuromyelitis optica spectrum disorders.

Romeo AR, Segal BM.

Curr Opin Rheumatol. 2019 May;31(3):250-255. doi: 10.1097/BOR.0000000000000603.

PMID:
30920972
6.

The Diversity of Encephalitogenic CD4+ T Cells in Multiple Sclerosis and Its Animal Models.

Segal BM.

J Clin Med. 2019 Jan 19;8(1). pii: E120. doi: 10.3390/jcm8010120. Review.

7.

Enhancing natural killer cells is beneficial in multiple sclerosis - Commentary.

Segal BM.

Mult Scler. 2019 Apr;25(4):513-514. doi: 10.1177/1352458518809296. Epub 2018 Nov 13. No abstract available.

PMID:
30421650
8.

CNS-resident classical DCs play a critical role in CNS autoimmune disease.

Giles DA, Duncker PC, Wilkinson NM, Washnock-Schmid JM, Segal BM.

J Clin Invest. 2018 Dec 3;128(12):5322-5334. doi: 10.1172/JCI123708. Epub 2018 Oct 29.

9.

An IFNγ/CXCL2 regulatory pathway determines lesion localization during EAE.

Stoolman JS, Duncker PC, Huber AK, Giles DA, Washnock-Schmid JM, Soulika AM, Segal BM.

J Neuroinflammation. 2018 Jul 16;15(1):208. doi: 10.1186/s12974-018-1237-y.

10.

A randomized, subject and rater-blinded, placebo-controlled trial of dimethyl fumarate for obstructive sleep apnea.

Braley TJ, Huber AK, Segal BM, Kaplish N, Saban R, Washnock-Schmid JM, Chervin RD.

Sleep. 2018 Aug 1;41(8). doi: 10.1093/sleep/zsy109.

PMID:
29800466
11.

Modulation of the Innate Immune System: A Future Approach to the Treatment of Neurological Disease.

Segal BM.

Clin Immunol. 2018 Apr;189:1-3. doi: 10.1016/j.clim.2018.03.003. No abstract available.

PMID:
29628125
12.
13.
14.

Myeloid cell plasticity in the evolution of central nervous system autoimmunity.

Giles DA, Washnock-Schmid JM, Duncker PC, Dahlawi S, Ponath G, Pitt D, Segal BM.

Ann Neurol. 2018 Jan;83(1):131-141. doi: 10.1002/ana.25128. Epub 2018 Jan 14.

15.

CD4+ T Cells Orchestrate Lethal Immune Pathology despite Fungal Clearance during Cryptococcus neoformans Meningoencephalitis.

Neal LM, Xing E, Xu J, Kolbe JL, Osterholzer JJ, Segal BM, Williamson PR, Olszewski MA.

MBio. 2017 Nov 21;8(6). pii: e01415-17. doi: 10.1128/mBio.01415-17.

16.

Minor salivary gland fibrosis in Sjögren's syndrome is elevated, associated with focus score and not solely a consequence of aging.

Leehan KM, Pezant NP, Rasmussen A, Grundahl K, Moore JS, Radfar L, Lewis DM, Stone DU, Lessard CJ, Rhodus NL, Segal BM, Scofield RH, Sivils KL, Montgomery C, Farris AD.

Clin Exp Rheumatol. 2018 May-Jun;36 Suppl 112(3):80-88. Epub 2017 Oct 23.

17.

Fatty infiltration of the minor salivary glands is a selective feature of aging but not Sjögren's syndrome.

Leehan KM, Pezant NP, Rasmussen A, Grundahl K, Moore JS, Radfar L, Lewis DM, Stone DU, Lessard CJ, Rhodus NL, Segal BM, Kaufman CE, Scofield RH, Sivils KL, Montgomery C, Farris AD.

Autoimmunity. 2017 Dec;50(8):451-457. doi: 10.1080/08916934.2017.1385776. Epub 2017 Oct 8.

18.

Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.

Li H, Reksten TR, Ice JA, Kelly JA, Adrianto I, Rasmussen A, Wang S, He B, Grundahl KM, Glenn SB, Miceli-Richard C, Bowman S, Lester S, Eriksson P, Eloranta ML, Brun JG, Gøransson LG, Harboe E, Guthridge JM, Kaufman KM, Kvarnström M, Cunninghame Graham DS, Patel K, Adler AJ, Farris AD, Brennan MT, Chodosh J, Gopalakrishnan R, Weisman MH, Venuturupalli S, Wallace DJ, Hefner KS, Houston GD, Huang AJW, Hughes PJ, Lewis DM, Radfar L, Vista ES, Edgar CE, Rohrer MD, Stone DU, Vyse TJ, Harley JB, Gaffney PM, James JA, Turner S, Alevizos I, Anaya JM, Rhodus NL, Segal BM, Montgomery CG, Scofield RH, Kovats S, Mariette X, Rönnblom L, Witte T, Rischmueller M, Wahren-Herlenius M, Omdal R, Jonsson R, Ng WF; for UK Primary Sjögren's Syndrome Registry, Nordmark G, Lessard CJ, Sivils KL.

PLoS Genet. 2017 Jun 22;13(6):e1006820. doi: 10.1371/journal.pgen.1006820. eCollection 2017 Jun.

19.

Speaking out about gender imbalance in invited speakers improves diversity.

Klein RS, Voskuhl R, Segal BM, Dittel BN, Lane TE, Bethea JR, Carson MJ, Colton C, Rosi S, Anderson A, Piccio L, Goverman JM, Benveniste EN, Brown MA, Tiwari-Woodruff SK, Harris TH, Cross AH.

Nat Immunol. 2017 Apr 18;18(5):475-478. doi: 10.1038/ni.3707. No abstract available.

20.

Effect of Tobacco Smoking on The Clinical, Histopathological, and Serological Manifestations of Sjögren's Syndrome.

Stone DU, Fife D, Brown M, Earley KE, Radfar L, Kaufman CE, Lewis DM, Rhodus NL, Segal BM, Wallace DJ, Weisman MH, Venuturupalli S, Brennan MT, Lessard CJ, Montgomery CG, Scofield RH, Sivils KL, Rasmussen A.

PLoS One. 2017 Feb 6;12(2):e0170249. doi: 10.1371/journal.pone.0170249. eCollection 2017.

21.

Effect of Template Reporting of Brain MRIs for Multiple Sclerosis on Report Thoroughness and Neurologist-Rated Quality: Results of a Prospective Quality Improvement Project.

Dickerson E, Davenport MS, Syed F, Stuve O, Cohen JA, Rinker JR, Goldman MD, Segal BM, Foerster BR; Michigan Radiology Quality Collaborative.

J Am Coll Radiol. 2017 Mar;14(3):371-379.e1. doi: 10.1016/j.jacr.2016.09.037. Epub 2016 Dec 5.

PMID:
27932248
22.

IL-12/IL-23p40 Is Highly Expressed in Secondary Lymphoid Organs and the CNS during All Stages of EAE, but Its Deletion Does Not Affect Disease Perpetuation.

Cravens PD, Hussain RZ, Miller-Little WA, Ben LH, Segal BM, Herndon E, Stüve O.

PLoS One. 2016 Oct 25;11(10):e0165248. doi: 10.1371/journal.pone.0165248. eCollection 2016.

23.

An emerging role for eotaxins in neurodegenerative disease.

Huber AK, Giles DA, Segal BM, Irani DN.

Clin Immunol. 2018 Apr;189:29-33. doi: 10.1016/j.clim.2016.09.010. Epub 2016 Sep 21. Review.

PMID:
27664933
24.

Antibodies to the RNA-binding protein hnRNP A1 contribute to neurodegeneration in a model of central nervous system autoimmune inflammatory disease.

Douglas JN, Gardner LA, Salapa HE, Lalor SJ, Lee S, Segal BM, Sawchenko PE, Levin MC.

J Neuroinflammation. 2016 Jul 8;13(1):178. doi: 10.1186/s12974-016-0647-y.

25.

T-bet promotes the accumulation of encephalitogenic Th17 cells in the CNS.

Grifka-Walk HM, Segal BM.

J Neuroimmunol. 2017 Mar 15;304:35-39. doi: 10.1016/j.jneuroim.2016.05.007. Epub 2016 May 24.

26.

Stable biomarker for plastic microglia.

Segal BM, Giger RJ.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3130-2. doi: 10.1073/pnas.1601669113. Epub 2016 Mar 10. No abstract available.

27.

Primary progressive multiple sclerosis--why we are failing.

Segal BM, Stüve O.

Lancet. 2016 Mar 12;387(10023):1032-1034. doi: 10.1016/S0140-6736(16)00158-6. Epub 2016 Jan 28. No abstract available.

PMID:
26827076
28.

CXCL13 promotes isotype-switched B cell accumulation to the central nervous system during viral encephalomyelitis.

Phares TW, DiSano KD, Stohlman SA, Segal BM, Bergmann CC.

Brain Behav Immun. 2016 May;54:128-139. doi: 10.1016/j.bbi.2016.01.016. Epub 2016 Jan 18.

29.

Genetic susceptibility loci of idiopathic interstitial pneumonia do not represent risk for systemic sclerosis: a case control study in Caucasian patients.

Wu M, Assassi S, Salazar GA, Pedroza C, Gorlova OY, Chen WV, Charles J, Taing ML, Liao K, Wigley FM, Hummers LK, Shah AA, Hinchcliff M, Khanna D, Schiopu E, Phillips K, Furst DE, Steen V, Baron M, Hudson M, Zhou X, Pope J, Jones N, Docherty P, Khalidi NA, Robinson D, Simms RW, Silver RM, Frech TM, Fessler BJ, Fritzler MJ, Molitor JA, Segal BM, Movahedian M, Martín J, Varga J, Mayes MD.

Arthritis Res Ther. 2016 Jan 20;18:20. doi: 10.1186/s13075-016-0923-3.

30.

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.

Liu K, Kurien BT, Zimmerman SL, Kaufman KM, Taft DH, Kottyan LC, Lazaro S, Weaver CA, Ice JA, Adler AJ, Chodosh J, Radfar L, Rasmussen A, Stone DU, Lewis DM, Li S, Koelsch KA, Igoe A, Talsania M, Kumar J, Maier-Moore JS, Harris VM, Gopalakrishnan R, Jonsson R, Lessard JA, Lu X, Gottenberg JE, Anaya JM, Cunninghame-Graham DS, Huang AJW, Brennan MT, Hughes P, Illei GG, Miceli-Richard C, Keystone EC, Bykerk VP, Hirschfield G, Xie G, Ng WF, Nordmark G, Eriksson P, Omdal R, Rhodus NL, Rischmueller M, Rohrer M, Segal BM, Vyse TJ, Wahren-Herlenius M, Witte T, Pons-Estel B, Alarcon-Riquelme ME, Guthridge JM, James JA, Lessard CJ, Kelly JA, Thompson SD, Gaffney PM, Montgomery CG, Edberg JC, Kimberly RP, Alarcón GS, Langefeld CL, Gilkeson GS, Kamen DL, Tsao BP, McCune WJ, Salmon JE, Merrill JT, Weisman MH, Wallace DJ, Utset TO, Bottinger EP, Amos CI, Siminovitch KA, Mariette X, Sivils KL, Harley JB, Scofield RH.

Arthritis Rheumatol. 2016 May;68(5):1290-1300. doi: 10.1002/art.39560.

31.

Th Cell Diversity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis.

Carbajal KS, Mironova Y, Ulrich-Lewis JT, Kulkarni D, Grifka-Walk HM, Huber AK, Shrager P, Giger RJ, Segal BM.

J Immunol. 2015 Sep 15;195(6):2552-9. doi: 10.4049/jimmunol.1501097. Epub 2015 Aug 3.

32.

IL-12-polarized Th1 cells produce GM-CSF and induce EAE independent of IL-23.

Grifka-Walk HM, Giles DA, Segal BM.

Eur J Immunol. 2015 Oct;45(10):2780-6. doi: 10.1002/eji.201545800. Epub 2015 Aug 14.

33.

The dual roles of immunity in ALS: injury overrides protection.

Murdock BJ, Bender DE, Segal BM, Feldman EL.

Neurobiol Dis. 2015 May;77:1-12. doi: 10.1016/j.nbd.2015.02.017. Epub 2015 Feb 26. Review.

PMID:
25726748
34.

Neuroinflammation triggered by β-glucan/dectin-1 signaling enables CNS axon regeneration.

Baldwin KT, Carbajal KS, Segal BM, Giger RJ.

Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2581-6. doi: 10.1073/pnas.1423221112. Epub 2015 Feb 9.

35.

Work disability, lost productivity and associated risk factors in patients diagnosed with systemic lupus erythematosus.

Utset TO, Baskaran A, Segal BM, Trupin L, Ogale S, Herberich E, Kalunian K.

Lupus Sci Med. 2015 Jan 20;2(1):e000058. doi: 10.1136/lupus-2014-000058. eCollection 2015.

36.

Antinuclear antibody-negative systemic sclerosis.

Salazar GA, Assassi S, Wigley F, Hummers L, Varga J, Hinchcliff M, Khanna D, Schiopu E, Phillips K, Furst DE, Steen V, Baron M, Hudson M, Taillefer SS, Pope J, Jones N, Docherty P, Khalidi NA, Robinson D, Simms RW, Silver RM, Frech TM, Fessler BJ, Molitor JA, Fritzler MJ, Segal BM, Al-Kassab F, Perry M, Yang J, Zamanian S, Reveille JD, Arnett FC, Pedroza C, Mayes MD.

Semin Arthritis Rheum. 2015 Jun;44(6):680-6. doi: 10.1016/j.semarthrit.2014.11.006. Epub 2014 Nov 28.

37.

Neutrophil-related factors as biomarkers in EAE and MS.

Rumble JM, Huber AK, Krishnamoorthy G, Srinivasan A, Giles DA, Zhang X, Wang L, Segal BM.

J Exp Med. 2015 Jan 12;212(1):23-35. doi: 10.1084/jem.20141015. Epub 2015 Jan 5.

38.

Hypnotic use and fatigue in multiple sclerosis.

Braley TJ, Segal BM, Chervin RD.

Sleep Med. 2015 Jan;16(1):131-7. doi: 10.1016/j.sleep.2014.09.006. Epub 2014 Sep 28.

PMID:
25454981
39.

Underrecognition of sleep disorders in patients with multiple sclerosis.

Braley TJ, Segal BM, Chervin RD.

J Clin Sleep Med. 2015 Jan 15;11(1):81. doi: 10.5664/jcsm.4378. No abstract available.

40.

Dysregulation of the IL-23/IL-17 axis and myeloid factors in secondary progressive MS.

Huber AK, Wang L, Han P, Zhang X, Ekholm S, Srinivasan A, Irani DN, Segal BM.

Neurology. 2014 Oct 21;83(17):1500-7. doi: 10.1212/WNL.0000000000000908. Epub 2014 Sep 24.

41.

Validation of the brief cognitive symptoms index in Sjögren syndrome.

Segal BM, Rhodus N, Moser Sivils KL, Solid CA.

J Rheumatol. 2014 Oct;41(10):2027-33. doi: 10.3899/jrheum.140362. Epub 2014 Sep 15.

PMID:
25225280
42.

The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.

Kottyan LC, Zoller EE, Bene J, Lu X, Kelly JA, Rupert AM, Lessard CJ, Vaughn SE, Marion M, Weirauch MT, Namjou B, Adler A, Rasmussen A, Glenn S, Montgomery CG, Hirschfield GM, Xie G, Coltescu C, Amos C, Li H, Ice JA, Nath SK, Mariette X, Bowman S; UK Primary Sjögren's Syndrome Registry, Rischmueller M, Lester S, Brun JG, Gøransson LG, Harboe E, Omdal R, Cunninghame-Graham DS, Vyse T, Miceli-Richard C, Brennan MT, Lessard JA, Wahren-Herlenius M, Kvarnström M, Illei GG, Witte T, Jonsson R, Eriksson P, Nordmark G, Ng WF; UK Primary Sjögren's Syndrome Registry, Anaya JM, Rhodus NL, Segal BM, Merrill JT, James JA, Guthridge JM, Scofield RH, Alarcon-Riquelme M, Bae SC, Boackle SA, Criswell LA, Gilkeson G, Kamen DL, Jacob CO, Kimberly R, Brown E, Edberg J, Alarcón GS, Reveille JD, Vilá LM, Petri M, Ramsey-Goldman R, Freedman BI, Niewold T, Stevens AM, Tsao BP, Ying J, Mayes MD, Gorlova OY, Wakeland W, Radstake T, Martin E, Martin J, Siminovitch K, Moser Sivils KL, Gaffney PM, Langefeld CD, Harley JB, Kaufman KM.

Hum Mol Genet. 2015 Jan 15;24(2):582-96. doi: 10.1093/hmg/ddu455. Epub 2014 Sep 8.

43.

In vitro polarization of T-helper cells.

Rumble J, Segal BM.

Methods Mol Biol. 2014;1193:105-13. doi: 10.1007/978-1-4939-1212-4_11.

PMID:
25151001
44.

Stage-specific immune dysregulation in multiple sclerosis.

Segal BM.

J Interferon Cytokine Res. 2014 Aug;34(8):633-40. doi: 10.1089/jir.2014.0025. Review.

45.

Obstructive sleep apnea is an under-recognized and consequential morbidity in multiple sclerosis.

Braley TJ, Segal BM, Chervin RD.

J Clin Sleep Med. 2014 Jun 15;10(6):709-10. doi: 10.5664/jcsm.3820. No abstract available.

46.

Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis.

Stoolman JS, Duncker PC, Huber AK, Segal BM.

J Immunol. 2014 Jul 15;193(2):564-70. doi: 10.4049/jimmunol.1400825. Epub 2014 Jun 13.

47.

Obstructive sleep apnea and fatigue in patients with multiple sclerosis.

Braley TJ, Segal BM, Chervin RD.

J Clin Sleep Med. 2014 Feb 15;10(2):155-62. doi: 10.5664/jcsm.3442.

48.

Pain in primary Sjögren's syndrome: the role of catastrophizing and negative illness perceptions.

Segal BM, Pogatchnik B, Rhodus N, Sivils KM, McElvain G, Solid CA.

Scand J Rheumatol. 2014;43(3):234-41. doi: 10.3109/03009742.2013.846409. Epub 2014 Jan 7.

PMID:
24392761
49.

Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis.

Mayes MD, Bossini-Castillo L, Gorlova O, Martin JE, Zhou X, Chen WV, Assassi S, Ying J, Tan FK, Arnett FC, Reveille JD, Guerra S, Teruel M, Carmona FD, Gregersen PK, Lee AT, López-Isac E, Ochoa E, Carreira P, Simeón CP, Castellví I, González-Gay MÁ; Spanish Scleroderma Group, Zhernakova A, Padyukov L, Alarcón-Riquelme M, Wijmenga C, Brown M, Beretta L, Riemekasten G, Witte T, Hunzelmann N, Kreuter A, Distler JH, Voskuyl AE, Schuerwegh AJ, Hesselstrand R, Nordin A, Airó P, Lunardi C, Shiels P, van Laar JM, Herrick A, Worthington J, Denton C, Wigley FM, Hummers LK, Varga J, Hinchcliff ME, Baron M, Hudson M, Pope JE, Furst DE, Khanna D, Phillips K, Schiopu E, Segal BM, Molitor JA, Silver RM, Steen VD, Simms RW, Lafyatis RA, Fessler BJ, Frech TM, Alkassab F, Docherty P, Kaminska E, Khalidi N, Jones HN, Markland J, Robinson D, Broen J, Radstake TR, Fonseca C, Koeleman BP, Martin J.

Am J Hum Genet. 2014 Jan 2;94(1):47-61. doi: 10.1016/j.ajhg.2013.12.002.

50.

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.

Lessard CJ, Li H, Adrianto I, Ice JA, Rasmussen A, Grundahl KM, Kelly JA, Dozmorov MG, Miceli-Richard C, Bowman S, Lester S, Eriksson P, Eloranta ML, Brun JG, Gøransson LG, Harboe E, Guthridge JM, Kaufman KM, Kvarnström M, Jazebi H, Cunninghame Graham DS, Grandits ME, Nazmul-Hossain AN, Patel K, Adler AJ, Maier-Moore JS, Farris AD, Brennan MT, Lessard JA, Chodosh J, Gopalakrishnan R, Hefner KS, Houston GD, Huang AJ, Hughes PJ, Lewis DM, Radfar L, Rohrer MD, Stone DU, Wren JD, Vyse TJ, Gaffney PM, James JA, Omdal R, Wahren-Herlenius M, Illei GG, Witte T, Jonsson R, Rischmueller M, Rönnblom L, Nordmark G, Ng WF; UK Primary Sjögren's Syndrome Registry, Mariette X, Anaya JM, Rhodus NL, Segal BM, Scofield RH, Montgomery CG, Harley JB, Sivils KL.

Nat Genet. 2013 Nov;45(11):1284-92. doi: 10.1038/ng.2792. Epub 2013 Oct 6.

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