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Items: 17


Daptomycin Dose-Ranging Evaluation with Single-Dose versus Multidose Ceftriaxone Combinations against Streptococcus mitis/oralis in an Ex Vivo Simulated Endocarditis Vegetation Model.

Kebriaei R, Rice SA, Stamper KC, Seepersaud R, Garcia-de-la-Maria C, Mishra NN, Miro JM, Arias CA, Tran TT, Sullam PM, Bayer AS, Rybak MJ.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00386-19. doi: 10.1128/AAC.00386-19. Print 2019 Jun.


Mutations in cdsA and pgsA Correlate with Daptomycin Resistance in Streptococcus mitis and S. oralis.

Tran TT, Mishra NN, Seepersaud R, Diaz L, Rios R, Dinh AQ, Garcia-de-la-Maria C, Rybak MJ, Miro JM, Shelburne SA, Sullam PM, Bayer AS, Arias CA.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01531-18. doi: 10.1128/AAC.01531-18. Print 2019 Feb.


Unraveling the sequence of cytosolic reactions in the export of GspB adhesin from Streptococcus gordonii.

Chen Y, Bensing BA, Seepersaud R, Mi W, Liao M, Jeffrey PD, Shajahan A, Sonon RN, Azadi P, Sullam PM, Rapoport TA.

J Biol Chem. 2018 Apr 6;293(14):5360-5373. doi: 10.1074/jbc.RA117.000963. Epub 2018 Feb 9.


O-acetylation of the serine-rich repeat glycoprotein GspB is coordinated with accessory Sec transport.

Seepersaud R, Sychantha D, Bensing BA, Clarke AJ, Sullam PM.

PLoS Pathog. 2017 Aug 21;13(8):e1006558. doi: 10.1371/journal.ppat.1006558. eCollection 2017 Aug.


Perturbations of Phosphatidate Cytidylyltransferase (CdsA) Mediate Daptomycin Resistance in Streptococcus mitis/oralis by a Novel Mechanism.

Mishra NN, Tran TT, Seepersaud R, Garcia-de-la-Maria C, Faull K, Yoon A, Proctor R, Miro JM, Rybak MJ, Bayer AS, Arias CA, Sullam PM.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02435-16. doi: 10.1128/AAC.02435-16. Print 2017 Apr.


Mechanism of a cytosolic O-glycosyltransferase essential for the synthesis of a bacterial adhesion protein.

Chen Y, Seepersaud R, Bensing BA, Sullam PM, Rapoport TA.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1190-9. doi: 10.1073/pnas.1600494113. Epub 2016 Feb 16.


Selective transport by SecA2: an expanding family of customized motor proteins.

Bensing BA, Seepersaud R, Yen YT, Sullam PM.

Biochim Biophys Acta. 2014 Aug;1843(8):1674-86. doi: 10.1016/j.bbamcr.2013.10.019. Epub 2013 Oct 31. Review.


Characterization of fibrinogen binding by glycoproteins Srr1 and Srr2 of Streptococcus agalactiae.

Seo HS, Minasov G, Seepersaud R, Doran KS, Dubrovska I, Shuvalova L, Anderson WF, Iverson TM, Sullam PM.

J Biol Chem. 2013 Dec 13;288(50):35982-96. doi: 10.1074/jbc.M113.513358. Epub 2013 Oct 28.


Differential localization of the streptococcal accessory sec components and implications for substrate export.

Yen YT, Cameron TA, Bensing BA, Seepersaud R, Zambryski PC, Sullam PM.

J Bacteriol. 2013 Feb;195(4):682-95. doi: 10.1128/JB.01742-12. Epub 2012 Nov 30.


The accessory Sec protein Asp2 modulates GlcNAc deposition onto the serine-rich repeat glycoprotein GspB.

Seepersaud R, Bensing BA, Yen YT, Sullam PM.

J Bacteriol. 2012 Oct;194(20):5564-75. Epub 2012 Aug 10.


A Specific interaction between SecA2 and a region of the preprotein adjacent to the signal peptide occurs during transport via the accessory Sec system.

Bensing BA, Yen YT, Seepersaud R, Sullam PM.

J Biol Chem. 2012 Jul 13;287(29):24438-47. doi: 10.1074/jbc.M112.378059. Epub 2012 May 31.


Asp2 and Asp3 interact directly with GspB, the export substrate of the Streptococcus gordonii accessory Sec System.

Yen YT, Seepersaud R, Bensing BA, Sullam PM.

J Bacteriol. 2011 Jul;193(13):3165-74. doi: 10.1128/JB.00057-11. Epub 2011 Apr 29.


Asp3 mediates multiple protein-protein interactions within the accessory Sec system of Streptococcus gordonii.

Seepersaud R, Bensing BA, Yen YT, Sullam PM.

Mol Microbiol. 2010 Oct;78(2):490-505. doi: 10.1111/j.1365-2958.2010.07346.x. Epub 2010 Sep 2.


Bacteriophage lysin mediates the binding of streptococcus mitis to human platelets through interaction with fibrinogen.

Seo HS, Xiong YQ, Mitchell J, Seepersaud R, Bayer AS, Sullam PM.

PLoS Pathog. 2010 Aug 12;6(8):e1001047. doi: 10.1371/journal.ppat.1001047.


Abundance of the delta subunit of RNA polymerase is linked to the virulence of Streptococcus agalactiae.

Seepersaud R, Needham RH, Kim CS, Jones AL.

J Bacteriol. 2006 Mar;188(6):2096-105.


Characterization of a novel leucine-rich repeat protein antigen from group B streptococci that elicits protective immunity.

Seepersaud R, Hanniffy SB, Mayne P, Sizer P, Le Page R, Wells JM.

Infect Immun. 2005 Mar;73(3):1671-83.


Expression of the AM gene locus in infective stages of Leishmania.

Dyall SD, Denny PW, Seepersaud R, McGhie D, Smith DF.

Mol Biochem Parasitol. 2000 Jun;109(1):73-9. No abstract available.


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