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Items: 1 to 50 of 1005

1.

Implication of in vivo circulating fibrocytes ablation in experimental pulmonary hypertension murine model.

Nikam VS, Nikam S, Sydykov A, Ahlbrecht K, Morty RE, Seeger W, Voswinckel R.

Br J Pharmacol. 2020 Feb 14. doi: 10.1111/bph.15025. [Epub ahead of print]

PMID:
32060903
2.

The Multi-Modal Effect of the Anti-fibrotic Drug Pirfenidone on NSCLC.

Marwitz S, Turkowski K, Nitschkowski D, Weigert A, Brandenburg J, Reiling N, Thomas M, Reck M, Drömann D, Seeger W, Rabe KF, Savai R, Goldmann T.

Front Oncol. 2020 Jan 21;9:1550. doi: 10.3389/fonc.2019.01550. eCollection 2019.

3.

Alterations in Doppler-derived renal venous stasis index during recompensation of right heart failure and fluid overload in a patient with pulmonary hypertension.

Husain-Syed F, Birk HW, Tello K, Richter MJ, Ronco C, McCullough PA, Schörmann T, Ferrari F, Yücel G, Yazdani B, Walmrath HD, Seeger W, Gall H, Ghofrani HA.

Rev Cardiovasc Med. 2019 Dec 30;20(4):263-266. doi: 10.31083/j.rcm.2019.04.564.

4.

Association of right atrial conduit phase with right ventricular lusitropic function in pulmonary hypertension.

Richter MJ, Fortuni F, Wiegand MA, Dalmer A, Vanderpool R, Ghofrani HA, Naeije R, Roller F, Seeger W, Sommer N, Gall H, Ghio S, Tello K.

Int J Cardiovasc Imaging. 2020 Jan 8. doi: 10.1007/s10554-019-01763-x. [Epub ahead of print]

PMID:
31912453
5.

Right ventricular function correlates of right atrial strain in pulmonary hypertension: a combined cardiac magnetic resonance and conductance catheter study.

Tello K, Dalmer A, Vanderpool R, Ghofrani HA, Naeije R, Roller F, Seeger W, Wiegand M, Gall H, Richter MJ.

Am J Physiol Heart Circ Physiol. 2020 Jan 1;318(1):H156-H164. doi: 10.1152/ajpheart.00485.2019. Epub 2019 Nov 22.

PMID:
31756118
6.

Targeting histone acetylation in pulmonary hypertension and right ventricular hypertrophy.

Chelladurai P, Boucherat O, Stenmark K, Kracht M, Seeger W, Bauer UM, Bonnet S, Pullamsetti SS.

Br J Pharmacol. 2019 Nov 20. doi: 10.1111/bph.14932. [Epub ahead of print] Review.

PMID:
31749139
7.

Response by Tello et al to Letter Regarding Article, "Validation of the Tricuspid Annular Plane Systolic Excursion/Systolic Pulmonary Artery Pressure Ratio for the Assessment of Right Ventricular-Arterial Coupling in Severe Pulmonary Hypertension".

Tello K, Ghofrani HA, Seeger W, Richter MJ, Naeije R.

Circ Cardiovasc Imaging. 2019 Nov;12(11):e010059. doi: 10.1161/CIRCIMAGING.119.010059. Epub 2019 Nov 13. No abstract available.

PMID:
31718275
8.

Epithelial cell plasticity defines heterogeneity in lung cancer.

Sarode P, Mansouri S, Karger A, Schaefer MB, Grimminger F, Seeger W, Savai R.

Cell Signal. 2020 Jan;65:109463. doi: 10.1016/j.cellsig.2019.109463. Epub 2019 Nov 3.

PMID:
31693875
9.

Characterization of GDF2 Mutations and Levels of BMP9 and BMP10 in Pulmonary Arterial Hypertension.

Hodgson J, Swietlik EM, Salmon RM, Hadinnapola C, Nikolic I, Wharton J, Guo J, Liley J, Haimel M, Bleda M, Southgate L, Machado RD, Martin JM, Treacy CM, Yates K, Daugherty LC, Shamardina O, Whitehorn D, Holden S, Bogaard HJ, Church C, Coghlan G, Condliffe R, Corris PA, Danesino C, Eyries M, Gall H, Ghio S, Ghofrani HA, Gibbs JSR, Girerd B, Houweling AC, Howard L, Humbert M, Kiely DG, Kovacs G, Lawrie A, MacKenzie Ross RV, Moledina S, Montani D, Olschewski A, Olschewski H, Ouwehand WH, Peacock AJ, Pepke-Zaba J, Prokopenko I, Rhodes CJ, Scelsi L, Seeger W, Soubrier F, Suntharalingam J, Toshner MR, Trembath RC, Vonk Noordegraaf A, Wort SJ, Wilkins MR, Yu PB, Li W, Gräf S, Upton PD, Morrell NW.

Am J Respir Crit Care Med. 2019 Oct 29. doi: 10.1164/rccm.201906-1141OC. [Epub ahead of print]

PMID:
31661308
10.

Doppler-Derived Renal Venous Stasis Index in the Prognosis of Right Heart Failure.

Husain-Syed F, Birk HW, Ronco C, Schörmann T, Tello K, Richter MJ, Wilhelm J, Sommer N, Steyerberg E, Bauer P, Walmrath HD, Seeger W, McCullough PA, Gall H, Ghofrani HA.

J Am Heart Assoc. 2019 Nov 5;8(21):e013584. doi: 10.1161/JAHA.119.013584. Epub 2019 Oct 19.

11.
12.

Acute response to rapid iloprost inhalation using the Breelib™ nebulizer in pulmonary arterial hypertension: the Breelib™ acute study.

Richter MJ, Wan J, Ghofrani HA, Seeger W, Gall H, Rieth A, Tello K.

Pulm Circ. 2019 Sep 11;9(3):2045894019875342. doi: 10.1177/2045894019875342. eCollection 2019 Jul-Sep.

13.

IRE1 Signaling As a Putative Therapeutic Target in Influenza Virus-induced Pneumonia.

Schmoldt C, Vazquez-Armendariz AI, Shalashova I, Selvakumar B, Bremer CM, Peteranderl C, Wasnick R, Witte B, Gattenlöhner S, Fink L, Vadász I, Morty RE, Pleschka S, Seeger W, Günther A, Herold S.

Am J Respir Cell Mol Biol. 2019 Oct;61(4):537-540. doi: 10.1165/rcmb.2019-0123LE. No abstract available.

PMID:
31573336
14.

Evaluation and Prognostic Relevance of Right Ventricular-Arterial Coupling in Pulmonary Hypertension.

Richter MJ, Peters D, Ghofrani HA, Naeije R, Roller F, Sommer N, Gall H, Grimminger F, Seeger W, Tello K.

Am J Respir Crit Care Med. 2020 Jan 1;201(1):116-119. doi: 10.1164/rccm.201906-1195LE. No abstract available.

PMID:
31539478
15.

Right heart failure in pulmonary hypertension: Diagnosis and new perspectives on vascular and direct right ventricular treatment.

Tello K, Seeger W, Naeije R, Vanderpool R, Ghofrani HA, Richter M, Tedford RJ, Bogaard HJ.

Br J Pharmacol. 2019 Sep 13. doi: 10.1111/bph.14866. [Epub ahead of print] Review.

PMID:
31517994
16.

Impaired right ventricular lusitropy is associated with ventilatory inefficiency in pulmonary arterial hypertension.

Tello K, Dalmer A, Vanderpool R, Ghofrani HA, Naeije R, Roller F, Seeger W, Dumitrescu D, Sommer N, Brunst A, Gall H, Richter MJ.

Eur Respir J. 2019 Nov 21;54(5). pii: 1900342. doi: 10.1183/13993003.00342-2019. Print 2019 Nov.

PMID:
31515402
17.

Validation of the Tricuspid Annular Plane Systolic Excursion/Systolic Pulmonary Artery Pressure Ratio for the Assessment of Right Ventricular-Arterial Coupling in Severe Pulmonary Hypertension.

Tello K, Wan J, Dalmer A, Vanderpool R, Ghofrani HA, Naeije R, Roller F, Mohajerani E, Seeger W, Herberg U, Sommer N, Gall H, Richter MJ.

Circ Cardiovasc Imaging. 2019 Sep;12(9):e009047. doi: 10.1161/CIRCIMAGING.119.009047. Epub 2019 Sep 10.

PMID:
31500448
18.

Is PKM2 Phosphorylation a Prerequisite for Oligomer Disassembly in Pulmonary Arterial Hypertension?

Novoyatleva T, Rai N, Weissmann N, Grimminger F, Ghofrani HA, Seeger W, Gall H, Schermuly RT.

Am J Respir Crit Care Med. 2019 Dec 15;200(12):1550-1554. doi: 10.1164/rccm.201904-0782LE. No abstract available.

PMID:
31486671
19.

Reply to Bogaard et al.: Emphysema Is-at the Most-Only a Mild Phenotype in the Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension.

Kojonazarov B, Hadzic S, Ghofrani HA, Grimminger F, Seeger W, Weissmann N, Schermuly RT.

Am J Respir Crit Care Med. 2019 Dec 1;200(11):1450-1452. doi: 10.1164/rccm.201907-1367LE. No abstract available.

20.

Susceptibility of microtubule-associated protein 1 light chain 3β (MAP1LC3B/LC3B) knockout mice to lung injury and fibrosis.

Kesireddy VS, Chillappagari S, Ahuja S, Knudsen L, Henneke I, Graumann J, Meiners S, Ochs M, Ruppert C, Korfei M, Seeger W, Mahavadi P.

FASEB J. 2019 Nov;33(11):12392-12408. doi: 10.1096/fj.201900854R. Epub 2019 Aug 20.

PMID:
31431059
21.

Clinical characteristics of patients with familial idiopathic pulmonary fibrosis (f-IPF).

Krauss E, Gehrken G, Drakopanagiotakis F, Tello S, Dartsch RC, Maurer O, Windhorst A, von der Beck D, Griese M, Seeger W, Guenther A.

BMC Pulm Med. 2019 Jul 18;19(1):130. doi: 10.1186/s12890-019-0895-6.

22.

Indefinite cytomegalovirus prophylaxis with valganciclovir after lung transplantation.

Hecker M, Hecker A, Askevold I, Kuhnert S, Reichert M, Guth S, Mayer E, Slanina H, Schüttler CG, Seeger W, Padberg W, Mayer K.

Transpl Infect Dis. 2019 Oct;21(5):e13138. doi: 10.1111/tid.13138. Epub 2019 Jul 18.

PMID:
31278878
23.

Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis.

Kheirollahi V, Wasnick RM, Biasin V, Vazquez-Armendariz AI, Chu X, Moiseenko A, Weiss A, Wilhelm J, Zhang JS, Kwapiszewska G, Herold S, Schermuly RT, Mari B, Li X, Seeger W, Günther A, Bellusci S, El Agha E.

Nat Commun. 2019 Jul 5;10(1):2987. doi: 10.1038/s41467-019-10839-0.

24.

[Hemodynamic Definition of Pulmonary Hypertension: Commentary on the Proposed Change by the 6th World Symposium on Pulmonary Hypertension].

Rosenkranz S, Diller GP, Dumitrescu D, Ewert R, Ghofrani HA, Grünig E, Halank M, Held M, Kaemmerer H, Klose H, Kovacs G, Konstantinides S, Lang IM, Lange TJ, Leuchte H, Mayer E, Olschewski A, Olschewski H, Olsson KM, Opitz C, Schermuly RT, Seeger W, Wilkens H, Hoeper MM.

Dtsch Med Wochenschr. 2019 Sep;144(19):1367-1372. doi: 10.1055/a-0918-3772. Epub 2019 Jul 5. German.

25.

Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis.

Rubio K, Singh I, Dobersch S, Sarvari P, Günther S, Cordero J, Mehta A, Wujak L, Cabrera-Fuentes H, Chao CM, Braubach P, Bellusci S, Seeger W, Günther A, Preissner KT, Wygrecka M, Savai R, Papy-Garcia D, Dobreva G, Heikenwalder M, Savai-Pullamsetti S, Braun T, Barreto G.

Nat Commun. 2019 May 20;10(1):2229. doi: 10.1038/s41467-019-10066-7.

26.

Targeting cyclin-dependent kinases for the treatment of pulmonary arterial hypertension.

Weiss A, Neubauer MC, Yerabolu D, Kojonazarov B, Schlueter BC, Neubert L, Jonigk D, Baal N, Ruppert C, Dorfmuller P, Pullamsetti SS, Weissmann N, Ghofrani HA, Grimminger F, Seeger W, Schermuly RT.

Nat Commun. 2019 May 17;10(1):2204. doi: 10.1038/s41467-019-10135-x.

27.

A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension.

Dabral S, Muecke C, Valasarajan C, Schmoranzer M, Wietelmann A, Semenza GL, Meister M, Muley T, Seeger-Nukpezah T, Samakovlis C, Weissmann N, Grimminger F, Seeger W, Savai R, Pullamsetti SS.

Nat Commun. 2019 May 13;10(1):2130. doi: 10.1038/s41467-019-10044-z.

28.

Exhalative Breath Markers Do Not Offer for Diagnosis of Interstitial Lung Diseases: Data from the European IPF Registry (eurIPFreg) and Biobank.

Krauss E, Froehler M, Degen M, Mahavadi P, Dartsch RC, Korfei M, Ruppert C, Seeger W, Guenther A.

J Clin Med. 2019 May 9;8(5). pii: E643. doi: 10.3390/jcm8050643.

29.

A simple echocardiographic estimate of right ventricular-arterial coupling to assess severity and outcome in pulmonary hypertension on chronic lung disease.

Tello K, Ghofrani HA, Heinze C, Krueger K, Naeije R, Raubach C, Seeger W, Sommer N, Gall H, Richter MJ.

Eur Respir J. 2019 Sep 12;54(3). pii: 1802435. doi: 10.1183/13993003.02435-2018. Print 2019 Sep. No abstract available.

PMID:
31073085
30.

Increased frequency of the restless legs syndrome in adults with cystic fibrosis.

Jurisch P, Gall H, Richter MJ, Seeger W, Nährlich L, Völkel S, Hirche TO, Schulz R.

Respir Med. 2019 May;151:8-10. doi: 10.1016/j.rmed.2019.03.009. Epub 2019 Mar 23.

PMID:
31047121
31.

Severe Emphysema in the SU5416/Hypoxia Rat Model of Pulmonary Hypertension.

Kojonazarov B, Hadzic S, Ghofrani HA, Grimminger F, Seeger W, Weissmann N, Schermuly RT.

Am J Respir Crit Care Med. 2019 Aug 15;200(4):515-518. doi: 10.1164/rccm.201902-0390LE. No abstract available.

PMID:
31034778
32.

Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells.

Klymenko O, Huehn M, Wilhelm J, Wasnick R, Shalashova I, Ruppert C, Henneke I, Hezel S, Guenther K, Mahavadi P, Samakovlis C, Seeger W, Guenther A, Korfei M.

J Mol Med (Berl). 2019 Jul;97(7):973-990. doi: 10.1007/s00109-019-01787-9. Epub 2019 Apr 26.

33.

Estimation of absolute number of alveolar epithelial type 2 cells in mouse lungs: a comparison between stereology and flow cytometry.

Dzhuraev G, Rodríguez-Castillo JA, Ruiz-Camp J, Salwig I, Szibor M, Vadász I, Herold S, Braun T, Ahlbrecht K, Atzberger A, Mühlfeld C, Seeger W, Morty RE.

J Microsc. 2019 Jul;275(1):36-50. doi: 10.1111/jmi.12800. Epub 2019 May 6.

PMID:
31020994
34.

Altered proteasome function in right ventricular hypertrophy.

Heitmeier T, Sydykov A, Lukas C, Vroom C, Korfei M, Petrovic A, Klingel K, Günther A, Eickelberg O, Weissmann N, Ghofrani HA, Seeger W, Grimminger F, Schermuly RT, Meiners S, Kosanovic D.

Cardiovasc Res. 2020 Feb 1;116(2):406-415. doi: 10.1093/cvr/cvz103.

PMID:
31020333
35.

Lamin B1 loss promotes lung cancer development and metastasis by epigenetic derepression of RET.

Jia Y, Vong JS, Asafova A, Garvalov BK, Caputo L, Cordero J, Singh A, Boettger T, Günther S, Fink L, Acker T, Barreto G, Seeger W, Braun T, Savai R, Dobreva G.

J Exp Med. 2019 Jun 3;216(6):1377-1395. doi: 10.1084/jem.20181394. Epub 2019 Apr 23.

36.

Process Evaluation of a Medical Student-Delivered Smoking Prevention Program for Secondary Schools: Protocol for the Education Against Tobacco Cluster Randomized Trial.

Brinker TJ, Buslaff F, Suhre JL, Silchmüller MP, Divizieva E, Wilhelm J, Hillebrand G, Penka D, Gaim B, Swoboda S, Baumermann S, Walther JW, Brieske CM, Jakob L, Baumert HM, Anhuef O, Schmidt SM, Alfitian J, Batra A, Taha L, Mons U, Hofmann FJ, Haney AC, Haney CM, Schaible S, Tran TA, Beißwenger H, Stark T, Groneberg DA, Seeger W, Srivastava A, Gall H, Holzapfel J, Rigotti NA, Baudson TG, Enk AH, Fröhling S, von Kalle C, Bernardes-Souza B, Pereira RMOS, Thomas R.

JMIR Res Protoc. 2019 Apr 11;8(4):e13508. doi: 10.2196/13508.

37.

Riociguat for treatment of pulmonary hypertension in COPD: a translational study.

Pichl A, Sommer N, Bednorz M, Seimetz M, Hadzic S, Kuhnert S, Kraut S, Roxlau ET, Kojonazarov B, Wilhelm J, Gredic M, Gall H, Tello K, Richter MJ, Pak O, Petrovic A, Hecker M, Schermuly RT, Grimminger F, Seeger W, Ghofrani HA, Weissmann N.

Eur Respir J. 2019 Jun 27;53(6). pii: 1802445. doi: 10.1183/13993003.02445-2018. Print 2019 Jun.

PMID:
30956210
38.

miR-574-5p as RNA decoy for CUGBP1 stimulates human lung tumor growth by mPGES-1 induction.

Saul MJ, Baumann I, Bruno A, Emmerich AC, Wellstein J, Ottinger SM, Contursi A, Dovizio M, Donnini S, Tacconelli S, Raouf J, Idborg H, Stein S, Korotkova M, Savai R, Terzuoli E, Sala G, Seeger W, Jakobsson PJ, Patrignani P, Suess B, Steinhilber D.

FASEB J. 2019 Jun;33(6):6933-6947. doi: 10.1096/fj.201802547R. Epub 2019 Mar 28.

PMID:
30922080
39.

[Chronic fibrosing lung diseases : Idiopathic pulmonary fibrosis from the perspective of its differential diagnosis].

Dartsch RC, Fink L, Breithecker A, Markart P, Tello S, Seeger W, Günther A.

Internist (Berl). 2019 Apr;60(4):345-361. doi: 10.1007/s00108-019-0571-1. German.

PMID:
30887071
40.

Cardiac Magnetic Resonance Imaging-Based Right Ventricular Strain Analysis for Assessment of Coupling and Diastolic Function in Pulmonary Hypertension.

Tello K, Dalmer A, Vanderpool R, Ghofrani HA, Naeije R, Roller F, Seeger W, Wilhelm J, Gall H, Richter MJ.

JACC Cardiovasc Imaging. 2019 Nov;12(11 Pt 1):2155-2164. doi: 10.1016/j.jcmg.2018.12.032. Epub 2019 Mar 13.

PMID:
30878422
41.

Protection against pressure overload-induced right heart failure by uncoupling protein 2 silencing.

Esfandiary A, Kutsche HS, Schreckenberg R, Weber M, Pak O, Kojonazarov B, Sydykov A, Hirschhäuser C, Wolf A, Haag D, Hecker M, Fink L, Seeger W, Ghofrani HA, Schermuly RT, Weißmann N, Schulz R, Rohrbach S, Li L, Sommer N, Schlüter KD.

Cardiovasc Res. 2019 Jun 1;115(7):1217-1227. doi: 10.1093/cvr/cvz049.

42.

Mouse genetic background impacts susceptibility to hyperoxia-driven perturbations to lung maturation.

Tiono J, Surate Solaligue DE, Mižíková I, Nardiello C, Vadász I, Böttcher-Friebertshäuser E, Ehrhardt H, Herold S, Seeger W, Morty RE.

Pediatr Pulmonol. 2019 Jul;54(7):1060-1077. doi: 10.1002/ppul.24304. Epub 2019 Mar 7.

PMID:
30848059
43.

Psychometric properties and minimal important differences of SF-36 in Idiopathic Pulmonary Fibrosis.

Witt S, Krauss E, Barbero MAN, Müller V, Bonniaud P, Vancheri C, Wells AU, Vasakova M, Pesci A, Klepetko W, Seeger W, Crestani B, Leidl R, Holle R, Schwarzkopf L, Guenther A.

Respir Res. 2019 Mar 1;20(1):47. doi: 10.1186/s12931-019-1010-5.

44.

Targeting miR-34a/Pdgfra interactions partially corrects alveologenesis in experimental bronchopulmonary dysplasia.

Ruiz-Camp J, Quantius J, Lignelli E, Arndt PF, Palumbo F, Nardiello C, Surate Solaligue DE, Sakkas E, Mižíková I, Rodríguez-Castillo JA, Vadász I, Richardson WD, Ahlbrecht K, Herold S, Seeger W, Morty RE.

EMBO Mol Med. 2019 Mar;11(3). pii: e9448. doi: 10.15252/emmm.201809448.

45.

Lung CT Densitometry in Idiopathic Pulmonary Fibrosis for the Prediction of Natural Course, Severity, and Mortality.

Loeh B, Brylski LT, von der Beck D, Seeger W, Krauss E, Bonniaud P, Crestani B, Vancheri C, Wells AU, Markart P, Breithecker A, Guenther A.

Chest. 2019 May;155(5):972-981. doi: 10.1016/j.chest.2019.01.019. Epub 2019 Feb 8.

PMID:
30742809
46.

Resolvin E1 Improves Mitochondrial Function in Human Alveolar Epithelial Cells during Severe Inflammation.

Mayer K, Sommer N, Hache K, Hecker A, Reiche S, Schneck E, Weissmann N, Seeger W, Hecker M.

Lipids. 2019 Jan;54(1):53-65. doi: 10.1002/lipd.12119. Epub 2019 Jan 29.

PMID:
30697748
47.

Multibeat Right Ventricular-Arterial Coupling during a Positive Acute Vasoreactivity Test.

Tello K, Dalmer A, Husain-Syed F, Seeger W, Naeije R, Ghofrani HA, Gall H, Richter MJ.

Am J Respir Crit Care Med. 2019 Jun 1;199(11):e41-e42. doi: 10.1164/rccm.201809-1787IM. No abstract available.

PMID:
30645142
48.

Response to: Comment on "Effect of Riociguat and Sildenafil on Right Heart Remodeling and Function in Pressure Overload Induced Model of Pulmonary Arterial Banding".

Rai N, Veeroju S, Schymura Y, Janssen W, Wietelmann A, Kojonazarov B, Weissmann N, Stasch JP, Ghofrani HA, Seeger W, Schermuly RT, Novoyatleva T.

Biomed Res Int. 2018 Dec 16;2018:7491284. doi: 10.1155/2018/7491284. eCollection 2018. No abstract available.

49.

Reserve of Right Ventricular-Arterial Coupling in the Setting of Chronic Overload.

Tello K, Dalmer A, Axmann J, Vanderpool R, Ghofrani HA, Naeije R, Roller F, Seeger W, Sommer N, Wilhelm J, Gall H, Richter MJ.

Circ Heart Fail. 2019 Jan;12(1):e005512. doi: 10.1161/CIRCHEARTFAILURE.118.005512.

PMID:
30616360
50.

Evidence for the Fucoidan/P-Selectin Axis as a Therapeutic Target in Hypoxia-induced Pulmonary Hypertension.

Novoyatleva T, Kojonazarov B, Owczarek A, Veeroju S, Rai N, Henneke I, Böhm M, Grimminger F, Ghofrani HA, Seeger W, Weissmann N, Schermuly RT.

Am J Respir Crit Care Med. 2019 Jun 1;199(11):1407-1420. doi: 10.1164/rccm.201806-1170OC.

PMID:
30557519

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