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Items: 11


Extension of the Notch intracellular domain ankyrin repeat stack by NRARP promotes feedback inhibition of Notch signaling.

Jarrett SM, Seegar TCM, Andrews M, Adelmant G, Marto JA, Aster JC, Blacklow SC.

Sci Signal. 2019 Nov 5;12(606). pii: eaay2369. doi: 10.1126/scisignal.aay2369.


Domain integration of ADAM family proteins: Emerging themes from structural studies.

Seegar TC, Blacklow SC.

Exp Biol Med (Maywood). 2019 Jul 23:1535370219865901. doi: 10.1177/1535370219865901. [Epub ahead of print] No abstract available.


Bispecific Forkhead Transcription Factor FoxN3 Recognizes Two Distinct Motifs with Different DNA Shapes.

Rogers JM, Waters CT, Seegar TCM, Jarrett SM, Hallworth AN, Blacklow SC, Bulyk ML.

Mol Cell. 2019 Apr 18;74(2):245-253.e6. doi: 10.1016/j.molcel.2019.01.019. Epub 2019 Feb 27.


Structural Basis for Regulated Proteolysis by the α-Secretase ADAM10.

Seegar TCM, Killingsworth LB, Saha N, Meyer PA, Patra D, Zimmerman B, Janes PW, Rubinstein E, Nikolov DB, Skiniotis G, Kruse AC, Blacklow SC.

Cell. 2017 Dec 14;171(7):1638-1648.e7. doi: 10.1016/j.cell.2017.11.014. Epub 2017 Dec 7.


Directed evolution provides insight into conformational substrate sampling by SrtA.

Suliman M, Santosh V, Seegar TCM, Dalton AC, Schultz KM, Klug CS, Barton WA.

PLoS One. 2017 Aug 31;12(8):e0184271. doi: 10.1371/journal.pone.0184271. eCollection 2017.


Structural Basis for Regulation of ESCRT-III Complexes by Lgd.

McMillan BJ, Tibbe C, Drabek AA, Seegar TCM, Blacklow SC, Klein T.

Cell Rep. 2017 May 30;19(9):1750-1757. doi: 10.1016/j.celrep.2017.05.026.


Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket.

Zimmerman B, Kelly B, McMillan BJ, Seegar TCM, Dror RO, Kruse AC, Blacklow SC.

Cell. 2016 Nov 3;167(4):1041-1051.e11. doi: 10.1016/j.cell.2016.09.056. Epub 2016 Oct 27.


Migrating Tundra Peregrine Falcons accumulate polycyclic aromatic hydrocarbons along Gulf of Mexico following Deepwater Horizon oil spill.

Seegar WS, Yates MA, Doney GE, Jenny JP, Seegar TC, Perkins C, Giovanni M.

Ecotoxicology. 2015 Jul;24(5):1102-11. doi: 10.1007/s10646-015-1450-8. Epub 2015 Mar 21.


Tie2 and Eph receptor tyrosine kinase activation and signaling.

Barton WA, Dalton AC, Seegar TC, Himanen JP, Nikolov DB.

Cold Spring Harb Perspect Biol. 2014 Mar 1;6(3). pii: a009142. doi: 10.1101/cshperspect.a009142. Review.


Structural basis for angiopoietin-1-mediated signaling initiation.

Yu X, Seegar TC, Dalton AC, Tzvetkova-Robev D, Goldgur Y, Rajashankar KR, Nikolov DB, Barton WA.

Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7205-10. doi: 10.1073/pnas.1216890110. Epub 2013 Apr 16.


Tie1-Tie2 interactions mediate functional differences between angiopoietin ligands.

Seegar TC, Eller B, Tzvetkova-Robev D, Kolev MV, Henderson SC, Nikolov DB, Barton WA.

Mol Cell. 2010 Mar 12;37(5):643-55. doi: 10.1016/j.molcel.2010.02.007.

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