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Items: 21


Genome replication dynamics of a bacteriophage and its satellite reveal strategies for parasitism and viral restriction.

Barth ZK, Silvas TV, Angermeyer A, Seed KD.

Nucleic Acids Res. 2019 Oct 31. pii: gkz1005. doi: 10.1093/nar/gkz1005. [Epub ahead of print]


Viral Satellites Exploit Phage Proteins to Escape Degradation of the Bacterial Host Chromosome.

McKitterick AC, Hays SG, Johura FT, Alam M, Seed KD.

Cell Host Microbe. 2019 Oct 9;26(4):504-514.e4. doi: 10.1016/j.chom.2019.09.006.


Competition between mobile genetic elements drives optimization of a phage-encoded CRISPR-Cas system: insights from a natural arms race.

McKitterick AC, LeGault KN, Angermeyer A, Alam M, Seed KD.

Philos Trans R Soc Lond B Biol Sci. 2019 May 13;374(1772):20180089. doi: 10.1098/rstb.2018.0089.


Megaphages infect Prevotella and variants are widespread in gut microbiomes.

Devoto AE, Santini JM, Olm MR, Anantharaman K, Munk P, Tung J, Archie EA, Turnbaugh PJ, Seed KD, Blekhman R, Aarestrup FM, Thomas BC, Banfield JF.

Nat Microbiol. 2019 Apr;4(4):693-700. doi: 10.1038/s41564-018-0338-9. Epub 2019 Jan 28.


Anti-phage islands force their target phage to directly mediate island excision and spread.

McKitterick AC, Seed KD.

Nat Commun. 2018 Jun 14;9(1):2348. doi: 10.1038/s41467-018-04786-5.


Analysis of 19 Highly Conserved Vibrio cholerae Bacteriophages Isolated from Environmental and Patient Sources Over a Twelve-Year Period.

Angermeyer A, Das MM, Singh DV, Seed KD.

Viruses. 2018 Jun 1;10(6). pii: E299. doi: 10.3390/v10060299.


A highly specific phage defense system is a conserved feature of the Vibrio cholerae mobilome.

O'Hara BJ, Barth ZK, McKitterick AC, Seed KD.

PLoS Genet. 2017 Jun 8;13(6):e1006838. doi: 10.1371/journal.pgen.1006838. eCollection 2017 Jun.


Functional Analysis of Bacteriophage Immunity through a Type I-E CRISPR-Cas System in Vibrio cholerae and Its Application in Bacteriophage Genome Engineering.

Box AM, McGuffie MJ, O'Hara BJ, Seed KD.

J Bacteriol. 2015 Nov 23;198(3):578-90. doi: 10.1128/JB.00747-15. Print 2016 Feb 1.


A globally distributed mobile genetic element inhibits natural transformation of Vibrio cholerae.

Dalia AB, Seed KD, Calderwood SB, Camilli A.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10485-90. doi: 10.1073/pnas.1509097112. Epub 2015 Aug 3.


Battling Phages: How Bacteria Defend against Viral Attack.

Seed KD.

PLoS Pathog. 2015 Jun 11;11(6):e1004847. doi: 10.1371/journal.ppat.1004847. eCollection 2015 Jun. Review. No abstract available.


Evolutionary consequences of intra-patient phage predation on microbial populations.

Seed KD, Yen M, Shapiro BJ, Hilaire IJ, Charles RC, Teng JE, Ivers LC, Boncy J, Harris JB, Camilli A.

Elife. 2014 Aug 26;3:e03497. doi: 10.7554/eLife.03497.


A bacteriophage encodes its own CRISPR/Cas adaptive response to evade host innate immunity.

Seed KD, Lazinski DW, Calderwood SB, Camilli A.

Nature. 2013 Feb 28;494(7438):489-91. doi: 10.1038/nature11927.


Phase variable O antigen biosynthetic genes control expression of the major protective antigen and bacteriophage receptor in Vibrio cholerae O1.

Seed KD, Faruque SM, Mekalanos JJ, Calderwood SB, Qadri F, Camilli A.

PLoS Pathog. 2012 Sep;8(9):e1002917. doi: 10.1371/journal.ppat.1002917. Epub 2012 Sep 13.


Evidence of a dominant lineage of Vibrio cholerae-specific lytic bacteriophages shed by cholera patients over a 10-year period in Dhaka, Bangladesh.

Seed KD, Bodi KL, Kropinski AM, Ackermann HW, Calderwood SB, Qadri F, Camilli A.

MBio. 2011 Feb 8;2(1):e00334-10. doi: 10.1128/mBio.00334-10. Print 2011.


Inactivation of Burkholderia cepacia complex phage KS9 gp41 identifies the phage repressor and generates lytic virions.

Lynch KH, Seed KD, Stothard P, Dennis JJ.

J Virol. 2010 Feb;84(3):1276-88. doi: 10.1128/JVI.01843-09. Epub 2009 Nov 25.


Experimental bacteriophage therapy increases survival of Galleria mellonella larvae infected with clinically relevant strains of the Burkholderia cepacia complex.

Seed KD, Dennis JJ.

Antimicrob Agents Chemother. 2009 May;53(5):2205-8. doi: 10.1128/AAC.01166-08. Epub 2009 Feb 17.


Genomic sequence and activity of KS10, a transposable phage of the Burkholderia cepacia complex.

Goudie AD, Lynch KH, Seed KD, Stothard P, Shrivastava S, Wishart DS, Dennis JJ.

BMC Genomics. 2008 Dec 18;9:615. doi: 10.1186/1471-2164-9-615.


Toward modern inhalational bacteriophage therapy: nebulization of bacteriophages of Burkholderia cepacia complex.

Golshahi L, Seed KD, Dennis JJ, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2008 Dec;21(4):351-60. doi: 10.1089/jamp.2008.0701.


Development of Galleria mellonella as an alternative infection model for the Burkholderia cepacia complex.

Seed KD, Dennis JJ.

Infect Immun. 2008 Mar;76(3):1267-75. doi: 10.1128/IAI.01249-07. Epub 2008 Jan 14.


Isolation and characterization of novel organic solvent-tolerant bacteria.

Zahir Z, Seed KD, Dennis JJ.

Extremophiles. 2006 Apr;10(2):129-38. Epub 2005 Oct 20.


Isolation and characterization of bacteriophages of the Burkholderia cepacia complex.

Seed KD, Dennis JJ.

FEMS Microbiol Lett. 2005 Oct 15;251(2):273-80.

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