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Items: 1 to 50 of 409

1.

Mucins and Pathogenic Mucin-Like Molecules Are Immunomodulators During Infection and Targets for Diagnostics and Vaccines.

Pinzón Martín S, Seeberger PH, Varón Silva D.

Front Chem. 2019 Oct 22;7:710. doi: 10.3389/fchem.2019.00710. eCollection 2019. Review.

2.

Synthetic Oligosaccharide-based Vaccines Protect Mice from Clostridioides difficile Infections.

Broecker F, Wegner E, Seco BMS, Kaplonek P, Bräutigam M, Ensser A, Pfister F, Daniel C, Martin CE, Mattner J, Seeberger PH.

ACS Chem Biol. 2019 Nov 6. doi: 10.1021/acschembio.9b00642. [Epub ahead of print]

PMID:
31692324
3.

Glycan size and attachment site location affect electron transfer dissociation (ETD) fragmentation and automated glycopeptide identification.

Alagesan K, Hinneburg H, Seeberger PH, Silva DV, Kolarich D.

Glycoconj J. 2019 Oct 21. doi: 10.1007/s10719-019-09888-w. [Epub ahead of print]

PMID:
31637569
4.

Immunological Evaluation of Synthetic Glycosylphosphatidylinositol Glycoconjugates as Vaccine Candidates against Malaria.

Malik A, Steinbeis F, Carillo MA, Seeberger PH, Lepenies B, Varón Silva D.

ACS Chem Biol. 2019 Oct 15. doi: 10.1021/acschembio.9b00739. [Epub ahead of print]

PMID:
31573796
5.

Thermodynamic and Structural Behavior of α-Galactosylceramide and C6-Functionalized α-GalCer in 2D Layers at the Air-Liquid Interface.

Brezesinski G, Calow ADJ, Pereira CL, Seeberger PH.

Chembiochem. 2019 Sep 22. doi: 10.1002/cbic.201900491. [Epub ahead of print]

PMID:
31544285
6.

Structural Studies Using Unnatural Oligosaccharides: Toward Sugar Foldamers.

Tyrikos-Ergas T, Fittolani G, Seeberger PH, Delbianco M.

Biomacromolecules. 2019 Sep 27. doi: 10.1021/acs.biomac.9b01090. [Epub ahead of print]

PMID:
31517479
7.

Advancing Solutions to the Carbohydrate Sequencing Challenge.

Gray CJ, Migas LG, Barran PE, Pagel K, Seeberger PH, Eyers CE, Boons GJ, Pohl NLB, Compagnon I, Widmalm G, Flitsch SL.

J Am Chem Soc. 2019 Sep 18;141(37):14463-14479. doi: 10.1021/jacs.9b06406. Epub 2019 Aug 21.

PMID:
31403778
8.

Detection of Anti-Toxoplasma gondii Antibodies in Human Sera Using Synthetic Glycosylphosphatidylinositol Glycans on a Bead-Based Multiplex Assay.

Garg M, Stern D, Groß U, Seeberger PH, Seeber F, Varón Silva D.

Anal Chem. 2019 Sep 3;91(17):11215-11222. doi: 10.1021/acs.analchem.9b02154. Epub 2019 Aug 22.

9.

Energy-Efficient Solar Photochemistry with Luminescent Solar Concentrator Based Photomicroreactors.

Cambié D, Dobbelaar J, Riente P, Vanderspikken J, Shen C, Seeberger PH, Gilmore K, Debije MG, Noël T.

Angew Chem Int Ed Engl. 2019 Oct 1;58(40):14374-14378. doi: 10.1002/anie.201908553. Epub 2019 Aug 23. Review.

10.

Systematic Hydrogen-Bond Manipulations To Establish Polysaccharide Structure-Property Correlations.

Yu Y, Tyrikos-Ergas T, Zhu Y, Fittolani G, Bordoni V, Singhal A, Fair RJ, Grafmüller A, Seeberger PH, Delbianco M.

Angew Chem Int Ed Engl. 2019 Sep 9;58(37):13127-13132. doi: 10.1002/anie.201906577. Epub 2019 Aug 19. Review.

11.

Multivalent glycan arrays.

Mende M, Bordoni V, Tsouka A, Loeffler FF, Delbianco M, Seeberger PH.

Faraday Discuss. 2019 Oct 30;219(0):9-32. doi: 10.1039/c9fd00080a.

PMID:
31298252
12.

Automated glycan assembly of Lewis type I and II oligosaccharide antigens.

Guberman M, Bräutigam M, Seeberger PH.

Chem Sci. 2019 Apr 29;10(21):5634-5640. doi: 10.1039/c9sc00768g. eCollection 2019 Jun 7.

13.

The C-type Lectin Receptor CLEC12A Recognizes Plasmodial Hemozoin and Contributes to Cerebral Malaria Development.

Raulf MK, Johannssen T, Matthiesen S, Neumann K, Hachenberg S, Mayer-Lambertz S, Steinbeis F, Hegermann J, Seeberger PH, Baumgärtner W, Strube C, Ruland J, Lepenies B.

Cell Rep. 2019 Jul 2;28(1):30-38.e5. doi: 10.1016/j.celrep.2019.06.015.

14.

Semiheterogeneous Dual Nickel/Photocatalytic (Thio)etherification Using Carbon Nitrides.

Cavedon C, Madani A, Seeberger PH, Pieber B.

Org Lett. 2019 Jul 5;21(13):5331-5334. doi: 10.1021/acs.orglett.9b01957. Epub 2019 Jun 24.

15.

Practical considerations for printing high-density glycan microarrays to study weak carbohydrate-protein interactions.

Ruprecht C, Geissner A, Seeberger PH, Pfrengle F.

Carbohydr Res. 2019 Jul 15;481:31-35. doi: 10.1016/j.carres.2019.06.006. Epub 2019 Jun 13.

PMID:
31228654
16.

MAIT cells as attractive vaccine targets.

Downey AM, Kapłonek P, Seeberger PH.

FEBS Lett. 2019 Jul;593(13):1627-1640. doi: 10.1002/1873-3468.13488. Epub 2019 Jun 27. Review.

PMID:
31206659
17.

Traceless Photolabile Linker Expedites the Chemical Synthesis of Complex Oligosaccharides by Automated Glycan Assembly.

Le Mai Hoang K, Pardo-Vargas A, Zhu Y, Yu Y, Loria M, Delbianco M, Seeberger PH.

J Am Chem Soc. 2019 Jun 5;141(22):9079-9086. doi: 10.1021/jacs.9b03769. Epub 2019 May 24.

18.

Carbohydrate-based nanomaterials for biomedical applications.

Gim S, Zhu Y, Seeberger PH, Delbianco M.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2019 Sep;11(5):e1558. doi: 10.1002/wnan.1558. Epub 2019 May 7. Review.

PMID:
31063240
19.

Semi-heterogeneous Dual Nickel/Photocatalysis using Carbon Nitrides: Esterification of Carboxylic Acids with Aryl Halides.

Pieber B, Malik JA, Cavedon C, Gisbertz S, Savateev A, Cruz D, Heil T, Zhang G, Seeberger PH.

Angew Chem Int Ed Engl. 2019 Jul 8;58(28):9575-9580. doi: 10.1002/anie.201902785. Epub 2019 Jun 6.

PMID:
31050132
20.

Automated Glycan Assembly: A Perspective.

Guberman M, Seeberger PH.

J Am Chem Soc. 2019 Apr 10;141(14):5581-5592. doi: 10.1021/jacs.9b00638. Epub 2019 Mar 28.

21.

Oligosaccharides Self-Assemble and Show Intrinsic Optical Properties.

Yu Y, Gim S, Kim D, Arnon ZA, Gazit E, Seeberger PH, Delbianco M.

J Am Chem Soc. 2019 Mar 27;141(12):4833-4838. doi: 10.1021/jacs.8b11882. Epub 2019 Mar 13.

22.

Microbe-focused glycan array screening platform.

Geissner A, Reinhardt A, Rademacher C, Johannssen T, Monteiro J, Lepenies B, Thépaut M, Fieschi F, Mrázková J, Wimmerova M, Schuhmacher F, Götze S, Grünstein D, Guo X, Hahm HS, Kandasamy J, Leonori D, Martin CE, Parameswarappa SG, Pasari S, Schlegel MK, Tanaka H, Xiao G, Yang Y, Pereira CL, Anish C, Seeberger PH.

Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):1958-1967. doi: 10.1073/pnas.1800853116. Epub 2019 Jan 22.

23.

High-density Peptide Arrays Help to Identify Linear Immunogenic B-cell Epitopes in Individuals Naturally Exposed to Malaria Infection.

Jaenisch T, Heiss K, Fischer N, Geiger C, Bischoff FR, Moldenhauer G, Rychlewski L, Sié A, Coulibaly B, Seeberger PH, Wyrwicz LS, Breitling F, Loeffler FF.

Mol Cell Proteomics. 2019 Apr;18(4):642-656. doi: 10.1074/mcp.RA118.000992. Epub 2019 Jan 10.

PMID:
30630936
24.

Improving vaccines against Streptococcus pneumoniae using synthetic glycans.

Kaplonek P, Khan N, Reppe K, Schumann B, Emmadi M, Lisboa MP, Xu FF, Calow ADJ, Parameswarappa SG, Witzenrath M, Pereira CL, Seeberger PH.

Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):13353-13358. doi: 10.1073/pnas.1811862115. Epub 2018 Dec 7.

25.

Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity.

Gerlach D, Guo Y, De Castro C, Kim SH, Schlatterer K, Xu FF, Pereira C, Seeberger PH, Ali S, Codée J, Sirisarn W, Schulte B, Wolz C, Larsen J, Molinaro A, Lee BL, Xia G, Stehle T, Peschel A.

Nature. 2018 Nov;563(7733):705-709. doi: 10.1038/s41586-018-0730-x. Epub 2018 Nov 21.

PMID:
30464342
26.

Publisher Correction: Unravelling the structure of glycosyl cations via cold-ion infrared spectroscopy.

Mucha E, Marianski M, Xu FF, Thomas DA, Meijer G, von Helden G, Seeberger PH, Pagel K.

Nat Commun. 2018 Nov 8;9(1):4767. doi: 10.1038/s41467-018-07184-z.

27.

Unravelling the structure of glycosyl cations via cold-ion infrared spectroscopy.

Mucha E, Marianski M, Xu FF, Thomas DA, Meijer G, von Helden G, Seeberger PH, Pagel K.

Nat Commun. 2018 Oct 9;9(1):4174. doi: 10.1038/s41467-018-06764-3. Erratum in: Nat Commun. 2018 Nov 8;9(1):4767.

28.

Mannose-Functionalized Nanoscaffolds for Targeted Delivery in Biomedical Applications.

Hu J, Wei P, Seeberger PH, Yin J.

Chem Asian J. 2018 Nov 16;13(22):3448-3459. doi: 10.1002/asia.201801088. Epub 2018 Oct 12. Review.

PMID:
30251341
29.

Comparative characterization of two galectins excreted-secreted from intestine-dwelling parasitic versus free-living females of the soil-transmitted nematode Strongyloides.

Ditgen D, Anandarajah EM, Reinhardt A, Younis AE, Witt S, Hansmann J, Lorenz E, García-Hernández M, Paclik D, Soblik H, Jolodar A, Seeberger PH, Liebau E, Brattig NW.

Mol Biochem Parasitol. 2018 Oct;225:73-83. doi: 10.1016/j.molbiopara.2018.08.008. Epub 2018 Sep 1.

PMID:
30179636
30.

Glycan Isomer Identification Using Ultraviolet Photodissociation Initiated Radical Chemistry.

Riggs DL, Hofmann J, Hahm HS, Seeberger PH, Pagel K, Julian RR.

Anal Chem. 2018 Oct 2;90(19):11581-11588. doi: 10.1021/acs.analchem.8b02958. Epub 2018 Sep 17.

PMID:
30179447
31.

An Empirical Understanding of the Glycosylation Reaction.

Chatterjee S, Moon S, Hentschel F, Gilmore K, Seeberger PH.

J Am Chem Soc. 2018 Sep 26;140(38):11942-11953. doi: 10.1021/jacs.8b04525. Epub 2018 Sep 18.

PMID:
30125122
32.

Chemoselective Photoredox Synthesis of Unprotected Primary Amines Using Ammonia.

Rong J, Seeberger PH, Gilmore K.

Org Lett. 2018 Jul 6;20(13):4081-4085. doi: 10.1021/acs.orglett.8b01637. Epub 2018 Jun 27.

PMID:
29947523
33.

Erratum for Diago-Navarro et al., "Novel, Broadly Reactive Anticapsular Antibodies against Carbapenem-Resistant Klebsiella pneumoniae Protect from Infection".

Diago-Navarro E, Motley MP, Ruiz-Peréz G, Yu W, Austin J, Seco BMS, Xiao G, Chikhalya A, Seeberger PH, Fries BC.

MBio. 2018 Jun 12;9(3). pii: e01005-18. doi: 10.1128/mBio.01005-18. No abstract available.

34.

Synthesis, Liposomal Formulation, and Immunological Evaluation of a Minimalistic Carbohydrate-α-GalCer Vaccine Candidate.

Broecker F, Götze S, Hudon J, Rathwell DCK, Pereira CL, Stallforth P, Anish C, Seeberger PH.

J Med Chem. 2018 Jun 14;61(11):4918-4927. doi: 10.1021/acs.jmedchem.8b00312. Epub 2018 May 18.

PMID:
29742893
35.

Automated glycan assembly as an enabling technology.

Pardo-Vargas A, Delbianco M, Seeberger PH.

Curr Opin Chem Biol. 2018 Oct;46:48-55. doi: 10.1016/j.cbpa.2018.04.007. Epub 2018 Apr 30. Review.

36.

Fucose Migration in Intact Protonated Glycan Ions: A Universal Phenomenon in Mass Spectrometry.

Mucha E, Lettow M, Marianski M, Thomas DA, Struwe WB, Harvey DJ, Meijer G, Seeberger PH, von Helden G, Pagel K.

Angew Chem Int Ed Engl. 2018 Jun 18;57(25):7440-7443. doi: 10.1002/anie.201801418. Epub 2018 May 25.

PMID:
29688603
37.

A modular synthetic route to size-defined immunogenic Haemophilus influenzae b antigens is key to the identification of an octasaccharide lead vaccine candidate.

Baek JY, Geissner A, Rathwell DCK, Meierhofer D, Pereira CL, Seeberger PH.

Chem Sci. 2017 Dec 11;9(5):1279-1288. doi: 10.1039/c7sc04521b. eCollection 2018 Feb 7.

38.

Development of an Efficacious, Semisynthetic Glycoconjugate Vaccine Candidate against Streptococcus pneumoniae Serotype 1.

Schumann B, Reppe K, Kaplonek P, Wahlbrink A, Anish C, Witzenrath M, Pereira CL, Seeberger PH.

ACS Cent Sci. 2018 Mar 28;4(3):357-361. doi: 10.1021/acscentsci.7b00504. Epub 2018 Mar 14.

39.

High affinity sugar ligands of C-type lectin receptor langerin.

Ota F, Hirayama T, Kizuka Y, Yamaguchi Y, Fujinawa R, Nagata M, Ismanto HS, Lepenies B, Aretz J, Rademacher C, Seeberger PH, Angata T, Kitazume S, Yoshida K, Betsuyaku T, Kida K, Yamasaki S, Taniguchi N.

Biochim Biophys Acta Gen Subj. 2018 Jul;1862(7):1592-1601. doi: 10.1016/j.bbagen.2018.04.004. Epub 2018 Apr 7.

PMID:
29631057
40.

Well-Defined Oligo- and Polysaccharides as Ideal Probes for Structural Studies.

Delbianco M, Kononov A, Poveda A, Yu Y, Diercks T, Jiménez-Barbero J, Seeberger PH.

J Am Chem Soc. 2018 Apr 25;140(16):5421-5426. doi: 10.1021/jacs.8b00254. Epub 2018 Apr 11.

PMID:
29624385
41.

Alterations of the Human Skin N- and O-Glycome in Basal Cell Carcinoma and Squamous Cell Carcinoma.

Möginger U, Grunewald S, Hennig R, Kuo CW, Schirmeister F, Voth H, Rapp E, Khoo KH, Seeberger PH, Simon JC, Kolarich D.

Front Oncol. 2018 Mar 21;8:70. doi: 10.3389/fonc.2018.00070. eCollection 2018.

42.

Novel, Broadly Reactive Anticapsular Antibodies against Carbapenem-Resistant Klebsiella pneumoniae Protect from Infection.

Diago-Navarro E, Motley MP, Ruiz-Peréz G, Yu W, Austin J, Seco BMS, Xiao G, Chikhalya A, Seeberger PH, Fries BC.

MBio. 2018 Apr 3;9(2). pii: e00091-18. doi: 10.1128/mBio.00091-18. Erratum in: MBio. 2018 Jun 12;9(3):.

43.

A Capping Step During Automated Glycan Assembly Enables Access to Complex Glycans in High Yield.

Yu Y, Kononov A, Delbianco M, Seeberger PH.

Chemistry. 2018 Apr 20;24(23):6075-6078. doi: 10.1002/chem.201801023. Epub 2018 Mar 25.

PMID:
29498436
44.

Literally Green Chemical Synthesis of Artemisinin from Plant Extracts.

Triemer S, Gilmore K, Vu GT, Seeberger PH, Seidel-Morgenstern A.

Angew Chem Int Ed Engl. 2018 May 4;57(19):5525-5528. doi: 10.1002/anie.201801424. Epub 2018 Apr 6.

PMID:
29465820
45.

Total Synthesis of a Densely Functionalized Plesiomonas shigelloides Serotype 51 Aminoglycoside Trisaccharide Antigen.

Qin C, Schumann B, Zou X, Pereira CL, Tian G, Hu J, Seeberger PH, Yin J.

J Am Chem Soc. 2018 Feb 28;140(8):3120-3127. doi: 10.1021/jacs.8b00148. Epub 2018 Feb 9.

PMID:
29377682
46.

Continuous Heterogeneous Photocatalysis in Serial Micro-Batch Reactors.

Pieber B, Shalom M, Antonietti M, Seeberger PH, Gilmore K.

Angew Chem Int Ed Engl. 2018 Jul 26;57(31):9976-9979. doi: 10.1002/anie.201712568. Epub 2018 Mar 13.

PMID:
29377383
47.

Flagellin Glycoproteomics of the Periodontitis Associated Pathogen Selenomonas sputigena Reveals Previously Not Described O-glycans and Rhamnose Fragment Rearrangement Occurring on the Glycopeptides.

Rath CB, Schirmeister F, Figl R, Seeberger PH, Schäffer C, Kolarich D.

Mol Cell Proteomics. 2018 Apr;17(4):721-736. doi: 10.1074/mcp.RA117.000394. Epub 2018 Jan 16.

48.

Identification of the Minimal Glycotope of Streptococcus pneumoniae 7F Capsular Polysaccharide using Synthetic Oligosaccharides.

Ménová P, Sella M, Sellrie K, Pereira CL, Seeberger PH.

Chemistry. 2018 Mar 15;24(16):4181-4187. doi: 10.1002/chem.201705379. Epub 2018 Feb 21.

PMID:
29333751
49.

Synergistic Glycosylation as Key to the Chemical Synthesis of an Outer Core Octasaccharide of Helicobacter pylori.

Zou X, Qin C, Pereira CL, Tian G, Hu J, Seeberger PH, Yin J.

Chemistry. 2018 Feb 26;24(12):2868-2872. doi: 10.1002/chem.201800049. Epub 2018 Jan 31.

PMID:
29319212
50.

Synthesis of Galactosylated Glycosylphosphatidylinositol Derivatives from Trypanosoma brucei.

Grube M, Lee BY, Garg M, Michel D, Vilotijević I, Malik A, Seeberger PH, Varón Silva D.

Chemistry. 2018 Mar 2;24(13):3271-3282. doi: 10.1002/chem.201705511. Epub 2018 Feb 1.

PMID:
29314341

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