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Items: 46

1.

Bioactive Sphingolipids as Biomarkers Predictive of Disease Severity and Treatment Response in Cancer: Current Status and Translational Challenges.

Sedić M, Grbčić P, Pavelić SK.

Anticancer Res. 2019 Jan;39(1):41-56. doi: 10.21873/anticanres.13078. Review.

PMID:
30591439
2.

Targeting tumour metastasis: the emerging role of nanotechnology.

Visentin S, Sedić M, Pavelić SK, Pavelić K.

Curr Med Chem. 2018 Dec 19. doi: 10.2174/0929867326666181220095343. [Epub ahead of print]

PMID:
30569844
3.

Correction for Giuntini et al., "Identification and Characterization of Human Monoclonal Antibodies for Immunoprophylaxis against Enterotoxigenic Escherichia coli Infection".

Giuntini S, Stoppato M, Sedic M, Ejemel M, Pondish JR, Wisheart D, Schiller ZA, Thomas WD Jr, Barry EM, Cavacini LA, Klempner MS, Wang Y.

Infect Immun. 2018 Nov 20;86(12). pii: e00713-18. doi: 10.1128/IAI.00713-18. Print 2018 Dec. No abstract available.

4.

Acid ceramidase inhibition sensitizes human colon cancer cells to oxaliplatin through downregulation of transglutaminase 2 and β1 integrin/FAK-mediated signalling.

Klobučar M, Grbčić P, Pavelić SK, Jonjić N, Visentin S, Sedić M.

Biochem Biophys Res Commun. 2018 Sep 5;503(2):843-848. doi: 10.1016/j.bbrc.2018.06.085. Epub 2018 Jun 21.

PMID:
29920241
5.

Identification and Characterization of Human Monoclonal Antibodies for Immunoprophylaxis against Enterotoxigenic Escherichia coli Infection.

Giuntini S, Stoppato M, Sedic M, Ejemel M, Pondish JR, Wisheart D, Schiller ZA, Thomas WD Jr, Barry EM, Cavacini LA, Klempner MS, Wang Y.

Infect Immun. 2018 Jul 23;86(8). pii: e00355-18. doi: 10.1128/IAI.00355-18. Print 2018 Aug. Erratum in: Infect Immun. 2018 Nov 20;86(12):.

6.

Eco-friendly synthesis, in vitro anti-proliferative evaluation, and 3D-QSAR analysis of a novel series of monocationic 2-aryl/heteroaryl-substituted 6-(2-imidazolinyl)benzothiazole mesylates.

Racané L, Ptiček L, Sedić M, Grbčić P, Kraljević Pavelić S, Bertoša B, Sović I, Karminski-Zamola G.

Mol Divers. 2018 Aug;22(3):723-741. doi: 10.1007/s11030-018-9827-2. Epub 2018 Apr 17.

PMID:
29667008
7.

In Vitro Photodynamic Activity of N-Methylated and N-Oxidised Tripyridyl Porphyrins with Long Alkyl Chains and Their Inhibitory Activity in Sphingolipid Metabolism.

Jelovica M, Grbčić P, Mušković M, Sedić M, Pavelić SK, Lončarić M, Malatesti N.

ChemMedChem. 2018 Feb 20;13(4):360-372. doi: 10.1002/cmdc.201700748. Epub 2018 Jan 30.

PMID:
29381258
8.

Small molecule purine and pseudopurine derivatives: synthesis, cytostatic evaluations and investigation of growth inhibitory effect in non-small cell lung cancer A549.

Bistrović A, Grbčić P, Harej A, Sedić M, Kraljević-Pavelić S, Koštrun S, Plavec J, Makuc D, Raić-Malić S.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):271-285. doi: 10.1080/14756366.2017.1414807.

9.

Safety Evaluation of Lipid Nanoparticle-Formulated Modified mRNA in the Sprague-Dawley Rat and Cynomolgus Monkey.

Sedic M, Senn JJ, Lynn A, Laska M, Smith M, Platz SJ, Bolen J, Hoge S, Bulychev A, Jacquinet E, Bartlett V, Smith PF.

Vet Pathol. 2018 Mar;55(2):341-354. doi: 10.1177/0300985817738095. Epub 2017 Nov 30.

PMID:
29191134
10.

Design, synthesis and biological evaluation of novel benzimidazole amidines as potent multi-target inhibitors for the treatment of non-small cell lung cancer.

Bistrović A, Krstulović L, Harej A, Grbčić P, Sedić M, Koštrun S, Pavelić SK, Bajić M, Raić-Malić S.

Eur J Med Chem. 2018 Jan 1;143:1616-1634. doi: 10.1016/j.ejmech.2017.10.061. Epub 2017 Nov 11.

PMID:
29133046
11.

Synthesis and Anti-Proliferative Effects of Mono- and Bis-Purinomimetics Targeting Kinases.

Bistrović A, Harej A, Grbčić P, Sedić M, Kraljević Pavelić S, Cetina M, Raić-Malić S.

Int J Mol Sci. 2017 Nov 1;18(11). pii: E2292. doi: 10.3390/ijms18112292.

12.

Epigenetic Reprogramming of Lineage-Committed Human Mammary Epithelial Cells Requires DNMT3A and Loss of DOT1L.

Breindel JL, Skibinski A, Sedic M, Wronski-Campos A, Zhou W, Keller PJ, Mills J, Bradner J, Onder T, Kuperwasser C.

Stem Cell Reports. 2017 Sep 12;9(3):943-955. doi: 10.1016/j.stemcr.2017.06.019. Epub 2017 Aug 3.

13.

Dual sphingosine kinase inhibitor SKI-II enhances sensitivity to 5-fluorouracil in hepatocellular carcinoma cells via suppression of osteopontin and FAK/IGF-1R signalling.

Grbčić P, Tomljanović I, Klobučar M, Kraljević Pavelić S, Lučin K, Sedić M.

Biochem Biophys Res Commun. 2017 Jun 10;487(4):782-788. doi: 10.1016/j.bbrc.2017.04.100. Epub 2017 Apr 19.

PMID:
28433634
14.

Novel pyrimidine-2,4-dione-1,2,3-triazole and furo[2,3-d]pyrimidine-2-one-1,2,3-triazole hybrids as potential anti-cancer agents: Synthesis, computational and X-ray analysis and biological evaluation.

Gregorić T, Sedić M, Grbčić P, Tomljenović Paravić A, Kraljević Pavelić S, Cetina M, Vianello R, Raić-Malić S.

Eur J Med Chem. 2017 Jan 5;125:1247-1267. doi: 10.1016/j.ejmech.2016.11.028. Epub 2016 Nov 14.

PMID:
27875779
15.

Synthesis, in vitro anticancer and antibacterial activities and in silico studies of new 4-substituted 1,2,3-triazole-coumarin hybrids.

Kraljević TG, Harej A, Sedić M, Pavelić SK, Stepanić V, Drenjančević D, Talapko J, Raić-Malić S.

Eur J Med Chem. 2016 Nov 29;124:794-808. doi: 10.1016/j.ejmech.2016.08.062. Epub 2016 Aug 31.

PMID:
27639370
16.

Basement membrane protein ladinin-1 and the MIF-CD44-β1 integrin signaling axis are implicated in laryngeal cancer metastasis.

Klobučar M, Sedić M, Gehrig P, Grossmann J, Bilić M, Kovač-Bilić L, Pavelić K, Kraljević Pavelić S.

Biochim Biophys Acta. 2016 Oct;1862(10):1938-54. doi: 10.1016/j.bbadis.2016.07.014. Epub 2016 Jul 25.

17.

Novel 2-Thienyl- and 2-Benzothienyl-Substituted 6-(2-Imidazolinyl)Benzothiazoles: Synthesis; in vitro Evaluation of Antitumor Effects and Assessment of Mitochondrial Toxicity.

Racané L, Sedić M, Ilić N, Aleksić M, Pavelić SK, Karminski-Zamola G.

Anticancer Agents Med Chem. 2017;17(1):57-66.

PMID:
27141878
18.

BRCA1-hapoinsufficiency: Unraveling the molecular and cellular basis for tissue-specific cancer.

Sedic M, Kuperwasser C.

Cell Cycle. 2016;15(5):621-7. doi: 10.1080/15384101.2016.1141841. Review.

19.

Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence.

Sedic M, Skibinski A, Brown N, Gallardo M, Mulligan P, Martinez P, Keller PJ, Glover E, Richardson AL, Cowan J, Toland AE, Ravichandran K, Riethman H, Naber SP, Näär AM, Blasco MA, Hinds PW, Kuperwasser C.

Nat Commun. 2015 Jun 24;6:7505. doi: 10.1038/ncomms8505.

20.

UV-induced retinal proteome changes in the rat model of age-related macular degeneration.

Kraljević Pavelić S, Klobučar M, Sedić M, Micek V, Gehrig P, Grossman J, Pavelić K, Vojniković B.

Biochim Biophys Acta. 2015 Sep;1852(9):1833-45. doi: 10.1016/j.bbadis.2015.06.006. Epub 2015 Jun 10.

21.

CoREST1 promotes tumor formation and tumor stroma interactions in a mouse model of breast cancer.

Mazumdar S, Arendt LM, Phillips S, Sedic M, Kuperwasser C, Gill G.

PLoS One. 2015 Mar 20;10(3):e0121281. doi: 10.1371/journal.pone.0121281. eCollection 2015.

22.

Resolving self-association of a therapeutic antibody by formulation optimization and molecular approaches.

Casaz P, Boucher E, Wollacott R, Pierce BG, Rivera R, Sedic M, Ozturk S, Thomas WD Jr, Wang Y.

MAbs. 2014;6(6):1533-9. doi: 10.4161/19420862.2014.975658.

23.

Label-free mass spectrometric profiling of urinary proteins and metabolites from paediatric idiopathic nephrotic syndrome.

Sedic M, Gethings LA, Vissers JP, Shockcor JP, McDonald S, Vasieva O, Lemac M, Langridge JI, Batinić D, Pavelić SK.

Biochem Biophys Res Commun. 2014 Sep 12;452(1):21-6. doi: 10.1016/j.bbrc.2014.08.016. Epub 2014 Aug 20.

PMID:
25150443
24.

Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation.

Phillips S, Prat A, Sedic M, Proia T, Wronski A, Mazumdar S, Skibinski A, Shirley SH, Perou CM, Gill G, Gupta PB, Kuperwasser C.

Stem Cell Reports. 2014 Apr 24;2(5):633-47. doi: 10.1016/j.stemcr.2014.03.008. eCollection 2014 May 6.

25.

Expression of growth hormone receptor, plakoglobin and NEDD9 protein in association with tumour progression and metastasis in human breast cancer.

Štajduhar E, Sedić M, Leniček T, Radulović P, Kerenji A, Krušlin B, Pavelić K, Kraljević Pavelić S.

Tumour Biol. 2014 Jul;35(7):6425-34. doi: 10.1007/s13277-014-1827-y. Epub 2014 Mar 28.

PMID:
24676793
26.

Novel coumarin derivatives containing 1,2,4-triazole, 4,5-dicyanoimidazole and purine moieties: synthesis and evaluation of their cytostatic activity.

Benci K, Mandić L, Suhina T, Sedić M, Klobučar M, Kraljević Pavelić S, Pavelić K, Wittine K, Mintas M.

Molecules. 2012 Sep 12;17(9):11010-25. doi: 10.3390/molecules170911010.

27.

Using functional genomics to identify drug targets: a Dupuytren's disease example.

Sedic M, Pavelic SK, Hock K.

Methods Mol Biol. 2012;910:15-31. doi: 10.1007/978-1-61779-965-5_2.

PMID:
22821590
28.

Novel 1,2,4-triazole and imidazole derivatives of L-ascorbic and imino-ascorbic acid: synthesis, anti-HCV and antitumor activity evaluations.

Wittine K, Stipković Babić M, Makuc D, Plavec J, Kraljević Pavelić S, Sedić M, Pavelić K, Leyssen P, Neyts J, Balzarini J, Mintas M.

Bioorg Med Chem. 2012 Jun 1;20(11):3675-85. doi: 10.1016/j.bmc.2012.01.054. Epub 2012 Feb 15.

PMID:
22555152
29.

Plasma biomarker identification in S-adenosylhomocysteine hydrolase deficiency.

Sedic M, Kraljevic Pavelic S, Cindric M, Vissers JP, Peronja M, Josic D, Cuk M, Fumic K, Pavelic K, Baric I.

Electrophoresis. 2011 Aug;32(15):1970-5. doi: 10.1002/elps.201000556. Epub 2011 Jul 6.

PMID:
21732553
30.

The new 5- or 6-azapyrimidine and cyanuric acid derivatives of l-ascorbic acid bearing the free C-5 hydroxy or C-4 amino group at the ethylenic spacer: CD-spectral absolute configuration determination and biological activity evaluations.

Wittine K, Babić MS, Košutić M, Cetina M, Rissanen K, Pavelić SK, Paravić AT, Sedić M, Pavelić K, Mintas M.

Eur J Med Chem. 2011 Jul;46(7):2770-85. doi: 10.1016/j.ejmech.2011.03.066. Epub 2011 Apr 6.

PMID:
21524828
31.

Metastasis: new perspectives on an old problem.

Kraljevic Pavelic S, Sedic M, Bosnjak H, Spaventi S, Pavelic K.

Mol Cancer. 2011 Feb 22;10:22. doi: 10.1186/1476-4598-10-22. Review.

32.

Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate.

Proia TA, Keller PJ, Gupta PB, Klebba I, Jones AD, Sedic M, Gilmore H, Tung N, Naber SP, Schnitt S, Lander ES, Kuperwasser C.

Cell Stem Cell. 2011 Feb 4;8(2):149-63. doi: 10.1016/j.stem.2010.12.007.

33.

Evaluation of in vitro biological activity of O-alkylated hydroxamic derivatives of some nonsteroidal anti-inflammatory drugs.

Pavelić SK, Sedić M, Poznić M, Rajić Z, Zorc B, Pavelić K, Balzarini J, Mintas M.

Anticancer Res. 2010 Oct;30(10):3987-94.

PMID:
21036712
34.

Differences between reversible (self-association) and irreversible aggregation of rHuG-CSF in carbohydrate and polyol formulations.

Pavišić R, Dodig I, Horvatić A, Mijić L, Sedić M, Linarić MR, Sovulj IG, Preočanin T, Krajačić MB, Cindrić M.

Eur J Pharm Biopharm. 2010 Nov;76(3):357-65. doi: 10.1016/j.ejpb.2010.09.006. Epub 2010 Sep 18.

PMID:
20854908
35.

The unsaturated acyclic nucleoside analogues bearing a sterically constrained (Z)-4'-benzamido-2'-butenyl moiety: Synthesis, X-ray crystal structure study, cytostatic and antiviral activity evaluations.

Benci K, Wittine K, Radan M, Cetina M, Sedić M, Kraljević Pavelić S, Pavelić K, Clercq ED, Mintas M.

Bioorg Med Chem. 2010 Sep 1;18(17):6249-57. doi: 10.1016/j.bmc.2010.07.035. Epub 2010 Aug 7.

PMID:
20696582
36.

Functional genomics in identification of drug targets in Dupuytren's contracture.

Sedic M, Jurisic D, Stanec Z, Hock K, Pavelic K, Kraljevic Pavelic S.

Front Biosci (Landmark Ed). 2010 Jan 1;15:57-64. Review.

PMID:
20036806
37.

Recombinant human granulocyte colony stimulating factor pre-screening and screening of stabilizing carbohydrates and polyols.

Pavisić R, Hock K, Mijić I, Horvatić A, Gecan M, Sedić M, Krajacić MB, Cindrić M.

Int J Pharm. 2010 Mar 15;387(1-2):110-9. doi: 10.1016/j.ijpharm.2009.12.015. Epub 2009 Dec 18.

PMID:
20005931
38.

An integrated proteomics approach for studying the molecular pathogenesis of Dupuytren's disease.

Kraljevic Pavelic S, Sedic M, Hock K, Vucinic S, Jurisic D, Gehrig P, Scott M, Schlapbach R, Cacev T, Kapitanovic S, Pavelic K.

J Pathol. 2009 Mar;217(4):524-33. doi: 10.1002/path.2483.

PMID:
19089850
39.

Differential antiproliferative mechanisms of novel derivative of benzimidazo[1,2-alpha]quinoline in colon cancer cells depending on their p53 status.

Sedic M, Poznic M, Gehrig P, Scott M, Schlapbach R, Hranjec M, Karminski-Zamola G, Pavelic K, Kraljevic Pavelic S.

Mol Cancer Ther. 2008 Jul;7(7):2121-32. doi: 10.1158/1535-7163.MCT-07-2261.

40.

Membrane morphology and leukotoxin secretion are associated with a novel membrane protein of Aggregatibacter actinomycetemcomitans.

Gallant CV, Sedic M, Chicoine EA, Ruiz T, Mintz KP.

J Bacteriol. 2008 Sep;190(17):5972-80. doi: 10.1128/JB.00548-08. Epub 2008 Jul 11.

41.

4. Global Approach to Biomedicine: Functional Genomics and Proteomics.

Pavelić K, Kralj M, Kraljević S, Sedić M.

EJIFCC. 2008 Apr 3;19(1):22-30. eCollection 2008 Apr. No abstract available.

42.

Novel cyano- and amidino-substituted derivatives of styryl-2-benzimidazoles and benzimidazo[1,2-a]quinolines. Synthesis, photochemical synthesis, DNA binding, and antitumor evaluation, part 3.

Hranjec M, Kralj M, Piantanida I, Sedić M, Suman L, Pavelić K, Karminski-Zamola G.

J Med Chem. 2007 Nov 15;50(23):5696-711. Epub 2007 Oct 13.

PMID:
17935309
43.

Casting light on molecular events underlying anti-cancer drug treatment: what can be seen from the proteomics point of view?

Kraljevic S, Sedic M, Scott M, Gehrig P, Schlapbach R, Pavelic K.

Cancer Treat Rev. 2006 Dec;32(8):619-29. Epub 2006 Oct 25. Review.

PMID:
17069979
44.

Global Approach to Biomedicine: Functional Genomics and Proteomics.

Pavelic K, Kralj M, Kraljevic S, Sedic M.

EJIFCC. 2005 May 17;16(2):22-26. eCollection 2005 May. No abstract available.

45.

Global approach to perinatal medicine: functional genomics and proteomics.

Kralj M, Kraljević S, Sedić M, Kurjak A, Pavelić K.

J Perinat Med. 2005;33(1):5-16. Review.

PMID:
15841607
46.

Sphingoid bases as possible diagnostic parameters.

Ribar S, Mesaric M, Sedic M.

Croat Med J. 2003 Apr;44(2):165-70.

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