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Items: 47

1.

Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination.

Martin RM, Ikeda K, Cromer MK, Uchida N, Nishimura T, Romano R, Tong AJ, Lemgart VT, Camarena J, Pavel-Dinu M, Sindhu C, Wiebking V, Vaidyanathan S, Dever DP, Bak RO, Laustsen A, Lesch BJ, Jakobsen MR, Sebastiano V, Nakauchi H, Porteus MH.

Cell Stem Cell. 2019 May 2;24(5):821-828.e5. doi: 10.1016/j.stem.2019.04.001.

PMID:
31051134
2.

Platelet-Rich Plasma (PRP) From Older Males With Knee Osteoarthritis Depresses Chondrocyte Metabolism and Upregulates Inflammation.

O'Donnell C, Migliore E, Grandi FC, Koltsov J, Lingampalli N, Cisar C, Indelli PF, Sebastiano V, Robinson WH, Bhutani N, Chu CR.

J Orthop Res. 2019 May 1. doi: 10.1002/jor.24322. [Epub ahead of print]

PMID:
31042308
3.

Replication study: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.

Kim J, Afshari A, Sengupta R, Sebastiano V, Gupta A, Kim YH; Reproducibility Project: Cancer Biology, Iorns E, Tsui R, Denis A, Perfito N, Errington TM, Iorns E, Tsui R, Denis A, Perfito N, Errington TM.

Elife. 2018 Dec 11;7. pii: e39944. doi: 10.7554/eLife.39944.

4.

Efficient scarless genome editing in human pluripotent stem cells.

Ikeda K, Uchida N, Nishimura T, White J, Martin RM, Nakauchi H, Sebastiano V, Weinberg KI, Porteus MH.

Nat Methods. 2018 Dec;15(12):1045-1047. doi: 10.1038/s41592-018-0212-y. Epub 2018 Nov 30.

PMID:
30504872
5.

Honey bee Royalactin unlocks conserved pluripotency pathway in mammals.

Wan DC, Morgan SL, Spencley AL, Mariano N, Chang EY, Shankar G, Luo Y, Li TH, Huh D, Huynh SK, Garcia JM, Dovey CM, Lumb J, Liu L, Brown KV, Bermudez A, Luong R, Zeng H, Mascetti VL, Pitteri SJ, Wang J, Tu H, Quarta M, Sebastiano V, Nusse R, Rando TA, Carette JE, Bazan JF, Wang KC.

Nat Commun. 2018 Dec 4;9(1):5078. doi: 10.1038/s41467-018-06256-4.

6.

A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells.

Fang F, Xia N, Angulo B, Carey J, Cady Z, Durruthy-Durruthy J, Bennett T, Sebastiano V, Reijo Pera RA.

Nat Commun. 2018 Oct 22;9(1):4384. doi: 10.1038/s41467-018-06908-5.

7.

Influenza virus infection causes global RNAPII termination defects.

Zhao N, Sebastiano V, Moshkina N, Mena N, Hultquist J, Jimenez-Morales D, Ma Y, Rialdi A, Albrecht R, Fenouil R, Sánchez-Aparicio MT, Ayllon J, Ravisankar S, Haddad B, Ho JSY, Low D, Jin J, Yurchenko V, Prinjha RK, Tarakhovsky A, Squatrito M, Pinto D, Allette K, Byun M, Smith ML, Sebra R, Guccione E, Tumpey T, Krogan N, Greenbaum B, van Bakel H, García-Sastre A, Marazzi I.

Nat Struct Mol Biol. 2018 Sep;25(9):885-893. doi: 10.1038/s41594-018-0124-7. Epub 2018 Sep 3.

PMID:
30177761
8.

Do Induced Pluripotent Stem Cell Characteristics Correlate with Efficient In Vitro Smooth Muscle Cell Differentiation? A Comparison of Three Patient-Derived Induced Pluripotent Stem Cell Lines.

Zhou Y, Kang G, Wen Y, Briggs M, Sebastiano V, Pederson R, Chen B.

Stem Cells Dev. 2018 Oct 15;27(20):1438-1448. doi: 10.1089/scd.2018.0031. Epub 2018 Aug 28.

PMID:
30153084
9.

NKX3-1 is required for induced pluripotent stem cell reprogramming and can replace OCT4 in mouse and human iPSC induction.

Mai T, Markov GJ, Brady JJ, Palla A, Zeng H, Sebastiano V, Blau HM.

Nat Cell Biol. 2018 Aug;20(8):900-908. doi: 10.1038/s41556-018-0136-x. Epub 2018 Jul 16.

10.

Single cell expression analysis of primate-specific retroviruses-derived HPAT lincRNAs in viable human blastocysts identifies embryonic cells co-expressing genetic markers of multiple lineages.

Glinsky G, Durruthy-Durruthy J, Wossidlo M, Grow EJ, Weirather JL, Au KF, Wysocka J, Sebastiano V.

Heliyon. 2018 Jun 28;4(6):e00667. doi: 10.1016/j.heliyon.2018.e00667. eCollection 2018 Jun.

11.

Use of human-derived stem cells to create a novel, in vitro model designed to explore FMR1 CGG repeat instability amongst female premutation carriers.

Gustin SLF, Wang G, Baker VM, Latham G, Sebastiano V.

J Assist Reprod Genet. 2018 Aug;35(8):1443-1455. doi: 10.1007/s10815-018-1237-y. Epub 2018 Jun 20.

12.

CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep.

Vilarino M, Rashid ST, Suchy FP, McNabb BR, van der Meulen T, Fine EJ, Ahsan S, Mursaliyev N, Sebastiano V, Diab SS, Huising MO, Nakauchi H, Ross PJ.

Sci Rep. 2017 Dec 12;7(1):17472. doi: 10.1038/s41598-017-17805-0.

13.

[Iron intake and HFE gen in male adults from Buenos Aires].

Felipoff AL, Fleischman SJ, Donadío ML, Sebastiano V, Castro M, Vellicce A, Rey JA, Lardo MM, Langini SH.

Medicina (B Aires). 2017;77(6):458-464. Spanish.

14.

Comprehensive comparison of Pacific Biosciences and Oxford Nanopore Technologies and their applications to transcriptome analysis.

Weirather JL, de Cesare M, Wang Y, Piazza P, Sebastiano V, Wang XJ, Buck D, Au KF.

Version 2. F1000Res. 2017 Feb 3 [revised 2017 Jan 1];6:100. doi: 10.12688/f1000research.10571.2. eCollection 2017.

15.

A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases.

Karakikes I, Termglinchan V, Cepeda DA, Lee J, Diecke S, Hendel A, Itzhaki I, Ameen M, Shrestha R, Wu H, Ma N, Shao NY, Seeger T, Woo N, Wilson KD, Matsa E, Porteus MH, Sebastiano V, Wu JC.

Circ Res. 2017 May 12;120(10):1561-1571. doi: 10.1161/CIRCRESAHA.116.309948. Epub 2017 Feb 28. Review.

16.

A semi-interpenetrating network of polyacrylamide and recombinant basement membrane allows pluripotent cell culture in a soft, ligand-rich microenvironment.

Price AJ, Huang EY, Sebastiano V, Dunn AR.

Biomaterials. 2017 Mar;121:179-192. doi: 10.1016/j.biomaterials.2016.12.005. Epub 2016 Dec 9.

PMID:
28088685
17.

Spatiotemporal Reconstruction of the Human Blastocyst by Single-Cell Gene-Expression Analysis Informs Induction of Naive Pluripotency.

Durruthy-Durruthy J, Wossidlo M, Pai S, Takahashi Y, Kang G, Omberg L, Chen B, Nakauchi H, Reijo Pera R, Sebastiano V.

Dev Cell. 2016 Jul 11;38(1):100-15. doi: 10.1016/j.devcel.2016.06.014.

18.

YAP Induces Human Naive Pluripotency.

Qin H, Hejna M, Liu Y, Percharde M, Wossidlo M, Blouin L, Durruthy-Durruthy J, Wong P, Qi Z, Yu J, Qi LS, Sebastiano V, Song JS, Ramalho-Santos M.

Cell Rep. 2016 Mar 15;14(10):2301-12. doi: 10.1016/j.celrep.2016.02.036. Epub 2016 Mar 3.

19.

Patenting parthenotes in the US and Europe.

Senatore V, Scott CT, Sebastiano V.

Nat Biotechnol. 2015 Dec 9;33(12):1232-1234. doi: 10.1038/nbt.3421. No abstract available.

PMID:
26650007
20.

The primate-specific noncoding RNA HPAT5 regulates pluripotency during human preimplantation development and nuclear reprogramming.

Durruthy-Durruthy J, Sebastiano V, Wossidlo M, Cepeda D, Cui J, Grow EJ, Davila J, Mall M, Wong WH, Wysocka J, Au KF, Reijo Pera RA.

Nat Genet. 2016 Jan;48(1):44-52. doi: 10.1038/ng.3449. Epub 2015 Nov 23.

21.

Lift NIH restrictions on chimera research.

Sharma A, Sebastiano V, Scott CT, Magnus D, Koyano-Nakagawa N, Garry DJ, Witte ON, Nakauchi H, Wu JC, Weissman IL, Wu SM.

Science. 2015 Nov 6;350(6261):640. doi: 10.1126/science.350.6261.640-a. Epub 2015 Nov 5. No abstract available.

22.

The transcriptome of human pluripotent stem cells.

Au KF, Sebastiano V.

Curr Opin Genet Dev. 2014 Oct;28:71-7. doi: 10.1016/j.gde.2014.09.012. Epub 2014 Oct 27. Review.

23.

Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa.

Sebastiano V, Zhen HH, Haddad B, Bashkirova E, Melo SP, Wang P, Leung TL, Siprashvili Z, Tichy A, Li J, Ameen M, Hawkins J, Lee S, Li L, Schwertschkow A, Bauer G, Lisowski L, Kay MA, Kim SK, Lane AT, Wernig M, Oro AE.

Sci Transl Med. 2014 Nov 26;6(264):264ra163. doi: 10.1126/scitranslmed.3009540. Erratum in: Sci Transl Med. 2014 Dec 17;6(267):267er8. Derafshi, Bahareh Haddad [corrected to Haddad, Bahareh].

24.

Derivation of GMP-compliant integration-free hiPSCs using modified mRNAs.

Durruthy JD, Sebastiano V.

Methods Mol Biol. 2015;1283:31-42. doi: 10.1007/7651_2014_124.

PMID:
25304205
25.

Germ cell nuclear factor regulates gametogenesis in developing gonads.

Sabour D, Xu X, Chung AC, Le Menuet D, Ko K, Tapia N, Araúzo-Bravo MJ, Gentile L, Greber B, Hübner K, Sebastiano V, Wu G, Schöler HR, Cooney AJ.

PLoS One. 2014 Aug 20;9(8):e103985. doi: 10.1371/journal.pone.0103985. eCollection 2014.

26.

Rapid and efficient conversion of integration-free human induced pluripotent stem cells to GMP-grade culture conditions.

Durruthy-Durruthy J, Briggs SF, Awe J, Ramathal CY, Karumbayaram S, Lee PC, Heidmann JD, Clark A, Karakikes I, Loh KM, Wu JC, Hoffman AR, Byrne J, Reijo Pera RA, Sebastiano V.

PLoS One. 2014 Apr 9;9(4):e94231. doi: 10.1371/journal.pone.0094231. eCollection 2014.

27.

Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing.

Hendel A, Kildebeck EJ, Fine EJ, Clark J, Punjya N, Sebastiano V, Bao G, Porteus MH.

Cell Rep. 2014 Apr 10;7(1):293-305. doi: 10.1016/j.celrep.2014.02.040. Epub 2014 Mar 27.

28.

Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations.

Loh KM, Ang LT, Zhang J, Kumar V, Ang J, Auyeong JQ, Lee KL, Choo SH, Lim CY, Nichane M, Tan J, Noghabi MS, Azzola L, Ng ES, Durruthy-Durruthy J, Sebastiano V, Poellinger L, Elefanty AG, Stanley EG, Chen Q, Prabhakar S, Weissman IL, Lim B.

Cell Stem Cell. 2014 Feb 6;14(2):237-52. doi: 10.1016/j.stem.2013.12.007. Epub 2014 Jan 9.

29.

Characterization of the human ESC transcriptome by hybrid sequencing.

Au KF, Sebastiano V, Afshar PT, Durruthy JD, Lee L, Williams BA, van Bakel H, Schadt EE, Reijo-Pera RA, Underwood JG, Wong WH.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):E4821-30. doi: 10.1073/pnas.1320101110. Epub 2013 Nov 26.

30.

SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients.

Shcheglovitov A, Shcheglovitova O, Yazawa M, Portmann T, Shu R, Sebastiano V, Krawisz A, Froehlich W, Bernstein JA, Hallmayer JF, Dolmetsch RE.

Nature. 2013 Nov 14;503(7475):267-71. doi: 10.1038/nature12618. Epub 2013 Oct 16.

31.

Establishment of totipotency does not depend on Oct4A.

Wu G, Han D, Gong Y, Sebastiano V, Gentile L, Singhal N, Adachi K, Fischedick G, Ortmeier C, Sinn M, Radstaak M, Tomilin A, Schöler HR.

Nat Cell Biol. 2013 Sep;15(9):1089-97. doi: 10.1038/ncb2816. Epub 2013 Aug 11.

32.

Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status.

Awe JP, Lee PC, Ramathal C, Vega-Crespo A, Durruthy-Durruthy J, Cooper A, Karumbayaram S, Lowry WE, Clark AT, Zack JA, Sebastiano V, Kohn DB, Pyle AD, Martin MG, Lipshutz GS, Phelps PE, Pera RA, Byrne JA.

Stem Cell Res Ther. 2013 Jul 26;4(4):87. doi: 10.1186/scrt246.

33.

Human amniotic mesenchymal stem cell-derived induced pluripotent stem cells may generate a universal source of cardiac cells.

Ge X, Wang IN, Toma I, Sebastiano V, Liu J, Butte MJ, Reijo Pera RA, Yang PC.

Stem Cells Dev. 2012 Oct 10;21(15):2798-808. doi: 10.1089/scd.2011.0435. Epub 2012 Jun 11.

34.

In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases.

Sebastiano V, Maeder ML, Angstman JF, Haddad B, Khayter C, Yeo DT, Goodwin MJ, Hawkins JS, Ramirez CL, Batista LF, Artandi SE, Wernig M, Joung JK.

Stem Cells. 2011 Nov;29(11):1717-26. doi: 10.1002/stem.718.

35.

Induction of human neuronal cells by defined transcription factors.

Pang ZP, Yang N, Vierbuchen T, Ostermeier A, Fuentes DR, Yang TQ, Citri A, Sebastiano V, Marro S, Südhof TC, Wernig M.

Nature. 2011 May 26;476(7359):220-3. doi: 10.1038/nature10202.

36.

Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells.

Batista LF, Pech MF, Zhong FL, Nguyen HN, Xie KT, Zaug AJ, Crary SM, Choi J, Sebastiano V, Cherry A, Giri N, Wernig M, Alter BP, Cech TR, Savage SA, Reijo Pera RA, Artandi SE.

Nature. 2011 May 22;474(7351):399-402. doi: 10.1038/nature10084.

37.

Embryonic stem cells, derived either after in vitro fertilization or nuclear transfer, prolong survival of semiallogeneic heart transplants.

Imberti B, Casiraghi F, Cugini D, Azzollini N, Cassis P, Todeschini M, Solini S, Sebastiano V, Zuccotti M, Garagna S, Redi CA, Noris M, Morigi M, Remuzzi G.

J Immunol. 2011 Apr 1;186(7):4164-74. doi: 10.4049/jimmunol.1000654. Epub 2011 Mar 9.

38.

Ultrastructural characterization of mouse embryonic stem cell-derived oocytes and granulosa cells.

Psathaki OE, Hübner K, Sabour D, Sebastiano V, Wu G, Sugawa F, Wieacker P, Pennekamp P, Schöler HR.

Stem Cells Dev. 2011 Dec;20(12):2205-15. doi: 10.1089/scd.2010.0575. Epub 2011 Mar 8.

PMID:
21244227
39.

Oct1 regulates trophoblast development during early mouse embryogenesis.

Sebastiano V, Dalvai M, Gentile L, Schubart K, Sutter J, Wu GM, Tapia N, Esch D, Ju JY, Hübner K, Bravo MJ, Schöler HR, Cavaleri F, Matthias P.

Development. 2010 Nov;137(21):3551-60. doi: 10.1242/dev.047027. Epub 2010 Sep 28.

40.

Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes.

Wossidlo M, Arand J, Sebastiano V, Lepikhov K, Boiani M, Reinhardt R, Schöler H, Walter J.

EMBO J. 2010 Jun 2;29(11):1877-88. doi: 10.1038/emboj.2010.80. Epub 2010 May 4.

41.

Induction of pluripotency in adult unipotent germline stem cells.

Ko K, Tapia N, Wu G, Kim JB, Bravo MJ, Sasse P, Glaser T, Ruau D, Han DW, Greber B, Hausdörfer K, Sebastiano V, Stehling M, Fleischmann BK, Brüstle O, Zenke M, Schöler HR.

Cell Stem Cell. 2009 Jul 2;5(1):87-96. doi: 10.1016/j.stem.2009.05.025.

42.

Oct4-induced pluripotency in adult neural stem cells.

Kim JB, Sebastiano V, Wu G, Araúzo-Bravo MJ, Sasse P, Gentile L, Ko K, Ruau D, Ehrich M, van den Boom D, Meyer J, Hübner K, Bernemann C, Ortmeier C, Zenke M, Fleischmann BK, Zaehres H, Schöler HR.

Cell. 2009 Feb 6;136(3):411-9. doi: 10.1016/j.cell.2009.01.023.

43.

Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors.

Kim JB, Zaehres H, Wu G, Gentile L, Ko K, Sebastiano V, Araúzo-Bravo MJ, Ruau D, Han DW, Zenke M, Schöler HR.

Nature. 2008 Jul 31;454(7204):646-50. doi: 10.1038/nature07061. Epub 2008 Jun 29.

PMID:
18594515
44.

Experimental demonstration that mammalian oocytes are not selective towards X- or Y-bearing sperm.

Zuccotti M, Sebastiano V, Garagna S, Redi CA.

Mol Reprod Dev. 2005 Jun;71(2):245-6.

PMID:
15791593
45.

Three-dimensional localization and dynamics of centromeres in mouse oocytes during folliculogenesis.

Garagna S, Merico V, Sebastiano V, Monti M, Orlandini G, Gatti R, Scandroglio R, Redi CA, Zuccotti M.

J Mol Histol. 2004 Aug;35(6):631-8.

PMID:
15614617
46.

Cloned pre-implantation mouse embryos show correct timing but altered levels of gene expression.

Sebastiano V, Gentile L, Garagna S, Redi CA, Zuccotti M.

Mol Reprod Dev. 2005 Feb;70(2):146-54.

PMID:
15570622
47.

Single-cell quantitative RT-PCR analysis of Cpt1b and Cpt2 gene expression in mouse antral oocytes and in preimplantation embryos.

Gentile L, Monti M, Sebastiano V, Merico V, Nicolai R, Calvani M, Garagna S, Redi CA, Zuccotti M.

Cytogenet Genome Res. 2004;105(2-4):215-21.

PMID:
15237209

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