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Items: 1 to 50 of 150

1.

Sex Differences in Genetic Associations With Longevity.

Zeng Y, Nie C, Min J, Chen H, Liu X, Ye R, Chen Z, Bai C, Xie E, Yin Z, Lv Y, Lu J, Li J, Ni T, Bolund L, Land KC, Yashin A, O'Rand AM, Sun L, Yang Z, Tao W, Gurinovich A, Franceschi C, Xie J, Gu J, Hou Y, Liu X, Xu X, Robine JM, Deelen J, Sebastiani P, Slagboom E, Perls T, Hauser E, Gottschalk W, Tan Q, Christensen K, Shi X, Lutz M, Tian XL, Yang H, Vaupel J.

JAMA Netw Open. 2018 Aug;1(4). pii: e181670. doi: 10.1001/jamanetworkopen.2018.1670. Epub 2018 Aug 24.

2.

APOE Alleles and Extreme Human Longevity.

Sebastiani P, Gurinovich A, Nygaard M, Sasaki T, Sweigart B, Bae H, Andersen SL, Villa F, Atzmon G, Christensen K, Arai Y, Barzilai N, Puca A, Christiansen L, Hirose N, Perls TT.

J Gerontol A Biol Sci Med Sci. 2018 Jul 27. doi: 10.1093/gerona/gly174. [Epub ahead of print]

PMID:
30060062
3.

Reduced Prevalence and Incidence of Cognitive Impairment Among Centenarian Offspring.

Andersen SL, Sweigart B, Sebastiani P, Drury J, Sidlowski S, Perls TT.

J Gerontol A Biol Sci Med Sci. 2018 Jun 20. doi: 10.1093/gerona/gly141. [Epub ahead of print]

PMID:
29931286
4.

Biomarker signatures of sickle cell disease severity.

Du M, Van Ness S, Gordeuk V, Nouraie SM, Nekhai S, Gladwin M, Steinberg MH, Sebastiani P.

Blood Cells Mol Dis. 2018 Sep;72:1-9. doi: 10.1016/j.bcmd.2018.05.001. Epub 2018 May 16.

PMID:
29778312
5.

Inflammatory signatures distinguish metabolic health in African American women with obesity.

Denis GV, Sebastiani P, Bertrand KA, Strissel KJ, Tran AH, Slama J, Medina ND, Andrieu G, Palmer JR.

PLoS One. 2018 May 8;13(5):e0196755. doi: 10.1371/journal.pone.0196755. eCollection 2018.

6.

Purpose in Life Among Centenarian Offspring.

Marone S, Bloore K, Sebastiani P, Flynn C, Leonard B, Whitaker K, Mostowy M, Perls T, Andersen SL.

J Gerontol B Psychol Sci Soc Sci. 2018 Mar 7. doi: 10.1093/geronb/gby023. [Epub ahead of print]

PMID:
29522128
7.

Sequestosome 1 Deficiency Delays, but Does Not Prevent Brain Damage Formation Following Acute Brain Injury in Adult Mice.

Sebastiani A, Gölz C, Sebastiani PG, Bobkiewicz W, Behl C, Mittmann T, Thal SC, Engelhard K.

Front Neurosci. 2017 Dec 19;11:678. doi: 10.3389/fnins.2017.00678. eCollection 2017.

8.

Assortative Mating by Ethnicity in Longevous Families.

Sebastiani P, Gurinovich A, Bae H, Andersen SL, Perls TT.

Front Genet. 2017 Nov 21;8:186. doi: 10.3389/fgene.2017.00186. eCollection 2017.

9.

HLA Typing and Celiac Disease in Moroccans.

Piancatelli D, Ben El Barhdadi I, Oumhani K, Sebastiani P, Colanardi A, Essaid A.

Med Sci (Basel). 2017 Jan 6;5(1). pii: E2. doi: 10.3390/medsci5010002.

10.

Effects of FOXO3 Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies.

Bae H, Gurinovich A, Malovini A, Atzmon G, Andersen SL, Villa F, Barzilai N, Puca A, Perls TT, Sebastiani P.

J Gerontol A Biol Sci Med Sci. 2018 Oct 8;73(11):1439-1447. doi: 10.1093/gerona/glx124.

PMID:
28977569
11.

Relationships Among Obesity, Type 2 Diabetes, and Plasma Cytokines in African American Women.

Denis GV, Sebastiani P, Andrieu G, Tran AH, Strissel KJ, Lombardi FL, Palmer JR.

Obesity (Silver Spring). 2017 Nov;25(11):1916-1920. doi: 10.1002/oby.21943. Epub 2017 Aug 25.

12.

A novel healthy blood pressure phenotype in the Long Life Family Study.

Marron MM, Singh J, Boudreau RM, Christensen K, Cosentino S, Feitosa MF, Minster RL, Perls T, Schupf N, Sebastiani P, Ukraintseva S, Wojczynski MK, Newman AB.

J Hypertens. 2018 Jan;36(1):43-53. doi: 10.1097/HJH.0000000000001514.

13.

A phased SNP-based classification of sickle cell anemia HBB haplotypes.

Shaikho EM, Farrell JJ, Alsultan A, Qutub H, Al-Ali AK, Figueiredo MS, Chui DHK, Farrer LA, Murphy GJ, Mostoslavsky G, Sebastiani P, Steinberg MH.

BMC Genomics. 2017 Aug 11;18(1):608. doi: 10.1186/s12864-017-4013-y.

14.

Genetic determinants of HbF in Saudi Arabian and African Benin haplotype sickle cell anemia.

Shaikho EM, Farrell JJ, Alsultan A, Sebastiani P, Steinberg MH.

Am J Hematol. 2017 Sep;92(9):E555-E557. doi: 10.1002/ajh.24822. Epub 2017 Jul 19. No abstract available.

15.

Uroplakin 3a+ Cells Are a Distinctive Population of Epithelial Progenitors that Contribute to Airway Maintenance and Post-injury Repair.

Guha A, Deshpande A, Jain A, Sebastiani P, Cardoso WV.

Cell Rep. 2017 Apr 11;19(2):246-254. doi: 10.1016/j.celrep.2017.03.051.

16.

Four Genome-Wide Association Studies Identify New Extreme Longevity Variants.

Sebastiani P, Gurinovich A, Bae H, Andersen S, Malovini A, Atzmon G, Villa F, Kraja AT, Ben-Avraham D, Barzilai N, Puca A, Perls TT.

J Gerontol A Biol Sci Med Sci. 2017 Oct 12;72(11):1453-1464. doi: 10.1093/gerona/glx027.

17.

Limitations and risks of meta-analyses of longevity studies.

Sebastiani P, Bae H, Gurinovich A, Soerensen M, Puca A, Perls TT.

Mech Ageing Dev. 2017 Jul;165(Pt B):139-146. doi: 10.1016/j.mad.2017.01.008. Epub 2017 Jan 28. Review.

18.

A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells.

Park S, Gianotti-Sommer A, Molina-Estevez FJ, Vanuytsel K, Skvir N, Leung A, Rozelle SS, Shaikho EM, Weir I, Jiang Z, Luo HY, Chui DHK, Figueiredo MS, Alsultan A, Al-Ali A, Sebastiani P, Steinberg MH, Mostoslavsky G, Murphy GJ.

Stem Cell Reports. 2017 Apr 11;8(4):1076-1085. doi: 10.1016/j.stemcr.2016.12.017. Epub 2017 Jan 19.

19.

The comparative safety of buprenorphine versus methadone in pregnancy-what about confounding?

Brogly SB, Saia K, Hernández-Diaz S, Werler M, Sebastiani P.

Addiction. 2016 Dec;111(12):2130-2131. doi: 10.1111/add.13551. No abstract available.

20.

Biomarker signatures of aging.

Sebastiani P, Thyagarajan B, Sun F, Schupf N, Newman AB, Montano M, Perls TT.

Aging Cell. 2017 Apr;16(2):329-338. doi: 10.1111/acel.12557. Epub 2017 Jan 6.

21.

Telomere length is longer in women with late maternal age.

Fagan E, Sun F, Bae H, Elo I, Andersen SL, Lee J, Christensen K, Thyagarajan B, Sebastiani P, Perls T, Honig LS, Schupf N; Long Life Family Study.

Menopause. 2017 May;24(5):497-501. doi: 10.1097/GME.0000000000000795.

22.

Age and Sex Distributions of Age-Related Biomarker Values in Healthy Older Adults from the Long Life Family Study.

Sebastiani P, Thyagarajan B, Sun F, Honig LS, Schupf N, Cosentino S, Feitosa MF, Wojczynski M, Newman AB, Montano M, Perls TT.

J Am Geriatr Soc. 2016 Nov;64(11):e189-e194. doi: 10.1111/jgs.14522. Epub 2016 Oct 26.

23.

A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia.

Vathipadiekal V, Farrell JJ, Wang S, Edward HL, Shappell H, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Simkin I, Farrer LA, Jiang Z, Luo HY, Huang S, Mostoslavsky G, Murphy GJ, Patra PK, Chui DH, Alsultan A, Al-Ali AK, Sebastiani P, Steinberg MH.

Am J Hematol. 2016 Nov;91(11):1118-1122. doi: 10.1002/ajh.24527. Epub 2016 Aug 22.

24.

Detection of Significant Groups in Hierarchical Clustering by Resampling.

Sebastiani P, Perls TT.

Front Genet. 2016 Aug 8;7:144. doi: 10.3389/fgene.2016.00144. eCollection 2016.

25.

Compression of Morbidity Is Observed Across Cohorts with Exceptional Longevity.

Ismail K, Nussbaum L, Sebastiani P, Andersen S, Perls T, Barzilai N, Milman S.

J Am Geriatr Soc. 2016 Aug;64(8):1583-91. doi: 10.1111/jgs.14222. Epub 2016 Jul 5.

26.

Variants of ZBTB7A (LRF) and its β-globin gene cluster binding motifs in sickle cell anemia.

Shaikho EM, Habara AH, Alsultan A, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Patra PK, Sebastiani P, Baltrusaitis K, Farrell JJ, Jiang Z, Luo HY, Chui DH, Al-Ali AK, Steinberg MH.

Blood Cells Mol Dis. 2016 Jul;59:49-51. doi: 10.1016/j.bcmd.2016.04.001. Epub 2016 Apr 13. No abstract available.

PMID:
27282567
27.

Homozygosity for a haplotype in the HBG2-OR51B4 region is exclusive to Arab-Indian haplotype sickle cell anemia.

Vathipadiekal V, Alsultan A, Baltrusaitis K, Farrell JJ, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Suliman A, Patra PK, Milton JN, Farrer LA, Chui DH, Al-Ali AK, Sebastiani P, Steinberg MH.

Am J Hematol. 2016 Jun;91(6):E308-11. doi: 10.1002/ajh.24368. Epub 2016 Apr 28. No abstract available.

28.

Learning Bayesian Networks from Correlated Data.

Bae H, Monti S, Montano M, Steinberg MH, Perls TT, Sebastiani P.

Sci Rep. 2016 May 5;6:25156. doi: 10.1038/srep25156.

29.

Kidney Transplantation, Polymorphisms of IL-18, and Other Pro-Inflammatory Genes and Late Post-Transplant Outcome.

Piancatelli D, Maccarone D, Colanardi A, Sebastiani P, Clemente K, Iesari S, Di Pietro V, Lai Q, Famulari A, Pisani F.

Transplant Proc. 2016 Mar;48(2):323-5. doi: 10.1016/j.transproceed.2016.02.010.

PMID:
27109946
30.

Familial Risk for Exceptional Longevity.

Sebastiani P, Andersen SL, McIntosh AI, Nussbaum L, Stevenson MD, Pierce L, Xia S, Salance K, Perls TT.

N Am Actuar J. 2016 Jan 1;20(1):57-64. Epub 2015 Oct 7.

31.

Original Research: A case-control genome-wide association study identifies genetic modifiers of fetal hemoglobin in sickle cell disease.

Liu L, Pertsemlidis A, Ding LH, Story MD, Steinberg MH, Sebastiani P, Hoppe C, Ballas SK, Pace BS.

Exp Biol Med (Maywood). 2016 Apr;241(7):706-18. doi: 10.1177/1535370216642047. Epub 2016 Mar 27.

32.

Novel loci and pathways significantly associated with longevity.

Zeng Y, Nie C, Min J, Liu X, Li M, Chen H, Xu H, Wang M, Ni T, Li Y, Yan H, Zhang JP, Song C, Chi LQ, Wang HM, Dong J, Zheng GY, Lin L, Qian F, Qi Y, Liu X, Cao H, Wang Y, Zhang L, Li Z, Zhou Y, Wang Y, Lu J, Li J, Qi M, Bolund L, Yashin A, Land KC, Gregory S, Yang Z, Gottschalk W, Tao W, Wang J, Wang J, Xu X, Bae H, Nygaard M, Christiansen L, Christensen K, Franceschi C, Lutz MW, Gu J, Tan Q, Perls T, Sebastiani P, Deelen J, Slagboom E, Hauser E, Xu H, Tian XL, Yang H, Vaupel JW.

Sci Rep. 2016 Feb 25;6:21243. doi: 10.1038/srep21243.

33.

Fast Room Temperature Very Low Field-Magnetic Resonance Imaging System Compatible with MagnetoEncephaloGraphy Environment.

Galante A, Sinibaldi R, Conti A, De Luca C, Catallo N, Sebastiani P, Pizzella V, Romani GL, Sotgiu A, Della Penna S.

PLoS One. 2015 Dec 2;10(12):e0142701. doi: 10.1371/journal.pone.0142701. eCollection 2015.

34.

Posttraumatic Propofol Neurotoxicity Is Mediated via the Pro-Brain-Derived Neurotrophic Factor-p75 Neurotrophin Receptor Pathway in Adult Mice.

Sebastiani A, Granold M, Ditter A, Sebastiani P, Gölz C, Pöttker B, Luh C, Schaible EV, Radyushkin K, Timaru-Kast R, Werner C, Schäfer MK, Engelhard K, Moosmann B, Thal SC.

Crit Care Med. 2016 Feb;44(2):e70-82. doi: 10.1097/CCM.0000000000001284.

PMID:
26317567
35.

Bayesian Polynomial Regression Models to Fit Multiple Genetic Models for Quantitative Traits.

Bae H, Perls T, Steinberg M, Sebastiani P.

Bayesian Anal. 2015 Mar;10(1):53-74.

36.

Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease.

Zhang X, Zhang W, Saraf SL, Nouraie M, Han J, Gowhari M, Hassan J, Miasnikova G, Sergueeva A, Nekhai S, Kittles R, Machado RF, Garcia JG, Gladwin MT, Steinberg MH, Sebastiani P, McClain DA, Gordeuk VR.

Hum Genet. 2015 Aug;134(8):895-904. doi: 10.1007/s00439-015-1572-3. Epub 2015 May 30.

37.

Temporal gene expression profiling of the rat knee joint capsule during immobilization-induced joint contractures.

Wong K, Sun F, Trudel G, Sebastiani P, Laneuville O.

BMC Musculoskelet Disord. 2015 May 26;16:125. doi: 10.1186/s12891-015-0588-0.

38.

Increasing Sibling Relative Risk of Survival to Older and Older Ages and the Importance of Precise Definitions of "Aging," "Life Span," and "Longevity".

Sebastiani P, Nussbaum L, Andersen SL, Black MJ, Perls TT.

J Gerontol A Biol Sci Med Sci. 2016 Mar;71(3):340-6. doi: 10.1093/gerona/glv020. Epub 2015 Mar 26.

39.

MICA∗078: A novel allele identified in a Moroccan individual affected by celiac disease.

Piancatelli D, Oumhani K, Benelbarhdadi I, Del Beato T, Colanardi A, Sebastiani P, Tessitore A, El Aouad R, Essaid A.

Hum Immunol. 2015 Jun;76(6):438-41. doi: 10.1016/j.humimm.2015.03.013. Epub 2015 Mar 20.

PMID:
25797203
40.

BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia.

Sebastiani P, Farrell JJ, Alsultan A, Wang S, Edward HL, Shappell H, Bae H, Milton JN, Baldwin CT, Al-Rubaish AM, Naserullah Z, Al-Muhanna F, Alsuliman A, Patra PK, Farrer LA, Ngo D, Vathipadiekal V, Chui DH, Al-Ali AK, Steinberg MH.

Blood Cells Mol Dis. 2015 Mar;54(3):224-30. doi: 10.1016/j.bcmd.2015.01.001. Epub 2015 Jan 30.

41.

Burden of disease variants in participants of the Long Life Family Study.

Stevenson M, Bae H, Schupf N, Andersen S, Zhang Q, Perls T, Sebastiani P.

Aging (Albany NY). 2015 Feb;7(2):123-32. Erratum in: Aging (Albany NY). 2015 Jun;7(6):450.

42.

Evaluation of an ensemble of genetic models for prediction of a quantitative trait.

Milton JN, Steinberg MH, Sebastiani P.

Front Genet. 2015 Jan 13;5:474. doi: 10.3389/fgene.2014.00474. eCollection 2014.

43.

An efficient technique for Bayesian modeling of family data using the BUGS software.

Bae HT, Perls TT, Sebastiani P.

Front Genet. 2014 Nov 18;5:390. doi: 10.3389/fgene.2014.00390. eCollection 2014.

44.

GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.

Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, Eirkisdottir G, Evans DA, Garcia ME, Hofman A, Kaplan RC, Kardia SL, Kiel DP, Oostra BA, Orwoll ES, Parimi N, Psaty BM, Rivadeneira F, Rotter JI, Seshadri S, Singleton A, Tiemeier H, Uitterlinden AG, Zhao W, Bandinelli S, Bennett DA, Ferrucci L, Gudnason V, Harris TB, Karasik D, Launer LJ, Perls TT, Slagboom PE, Tranah GJ, Weir DR, Newman AB, van Duijn CM, Murabito JM.

J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):110-8. doi: 10.1093/gerona/glu166. Epub 2014 Sep 8.

45.

Prenatal buprenorphine versus methadone exposure and neonatal outcomes: systematic review and meta-analysis.

Brogly SB, Saia KA, Walley AY, Du HM, Sebastiani P.

Am J Epidemiol. 2014 Oct 1;180(7):673-86. doi: 10.1093/aje/kwu190. Epub 2014 Aug 22. Review.

PMID:
25150272
46.

Involvement of IL-6 and IL-1 receptor antagonist on intellectual disability.

Aureli A, Sebastiani P, Del Beato T, Marimpietri AE, Graziani A, Sechi E, Di Loreto S.

Immunol Lett. 2014 Nov;162(1 Pt A):124-31. doi: 10.1016/j.imlet.2014.08.003. Epub 2014 Aug 11.

47.

The genetics of hemoglobin A2 regulation in sickle cell anemia.

Griffin PJ, Sebastiani P, Edward H, Baldwin CT, Gladwin MT, Gordeuk VR, Chui DH, Steinberg MH.

Am J Hematol. 2014 Nov;89(11):1019-23. doi: 10.1002/ajh.23811. Epub 2014 Aug 4.

48.

Extended maternal age at birth of last child and women's longevity in the Long Life Family Study.

Sun F, Sebastiani P, Schupf N, Bae H, Andersen SL, McIntosh A, Abel H, Elo IT, Perls TT.

Menopause. 2015 Jan;22(1):26-31. doi: 10.1097/GME.0000000000000276.

49.

Regular and moderate exercise initiated in middle age prevents age-related amyloidogenesis and preserves synaptic and neuroprotective signaling in mouse brain cortex.

Di Loreto S, Falone S, D'Alessandro A, Santini S Jr, Sebastiani P, Cacchio M, Amicarelli F.

Exp Gerontol. 2014 Sep;57:57-65. doi: 10.1016/j.exger.2014.05.006. Epub 2014 May 14.

50.

Prediction of fetal hemoglobin in sickle cell anemia using an ensemble of genetic risk prediction models.

Milton JN, Gordeuk VR, Taylor JG 6th, Gladwin MT, Steinberg MH, Sebastiani P.

Circ Cardiovasc Genet. 2014 Apr;7(2):110-5. doi: 10.1161/CIRCGENETICS.113.000387. Epub 2014 Mar 1.

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