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Items: 50

1.

Breast cancer survivors reduce accelerometer-measured sedentary time in an exercise intervention.

Weiner LS, Takemoto M, Godbole S, Nelson SH, Natarajan L, Sears DD, Hartman SJ.

J Cancer Surviv. 2019 Jun;13(3):468-476. doi: 10.1007/s11764-019-00768-8. Epub 2019 May 29.

PMID:
31144265
2.

Association of Low Fasting Glucose and HbA1c With Cardiovascular Disease and Mortality: The MESA Study.

Mongraw-Chaffin M, Bertoni AG, Golden SH, Mathioudakis N, Sears DD, Szklo M, Anderson CAM.

J Endocr Soc. 2019 Mar 1;3(5):892-901. doi: 10.1210/js.2019-00033. eCollection 2019 May 1.

3.

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.

Garrett-Bakelman FE, Darshi M, Green SJ, Gur RC, Lin L, Macias BR, McKenna MJ, Meydan C, Mishra T, Nasrini J, Piening BD, Rizzardi LF, Sharma K, Siamwala JH, Taylor L, Vitaterna MH, Afkarian M, Afshinnekoo E, Ahadi S, Ambati A, Arya M, Bezdan D, Callahan CM, Chen S, Choi AMK, Chlipala GE, Contrepois K, Covington M, Crucian BE, De Vivo I, Dinges DF, Ebert DJ, Feinberg JI, Gandara JA, George KA, Goutsias J, Grills GS, Hargens AR, Heer M, Hillary RP, Hoofnagle AN, Hook VYH, Jenkinson G, Jiang P, Keshavarzian A, Laurie SS, Lee-McMullen B, Lumpkins SB, MacKay M, Maienschein-Cline MG, Melnick AM, Moore TM, Nakahira K, Patel HH, Pietrzyk R, Rao V, Saito R, Salins DN, Schilling JM, Sears DD, Sheridan CK, Stenger MB, Tryggvadottir R, Urban AE, Vaisar T, Van Espen B, Zhang J, Ziegler MG, Zwart SR, Charles JB, Kundrot CE, Scott GBI, Bailey SM, Basner M, Feinberg AP, Lee SMC, Mason CE, Mignot E, Rana BK, Smith SM, Snyder MP, Turek FW.

Science. 2019 Apr 12;364(6436). pii: eaau8650. doi: 10.1126/science.aau8650.

PMID:
30975860
4.

Arriba por la Vida Estudio (AVE): Study protocol for a standing intervention targeting postmenopausal Latinas.

Takemoto M, Schechtman M, Villa N, Talavera G, Sears DD, Natarajan L, Owen N, Rosenberg DE, Dunstan D, Allison M, Kerr J.

Contemp Clin Trials. 2019 Apr;79:66-72. doi: 10.1016/j.cct.2019.02.004. Epub 2019 Feb 13.

PMID:
30771560
5.

Protocol for a cross sectional study of cancer risk, environmental exposures and lifestyle behaviors in a diverse community sample: the Community of Mine study.

Jankowska MM, Sears DD, Natarajan L, Martinez E, Anderson CAM, Sallis JF, Matthews SA, Crist K, Dillon L, Johnson E, Barrera-Ng A, Full K, Godbole S, Kerr J.

BMC Public Health. 2019 Feb 13;19(1):186. doi: 10.1186/s12889-019-6501-2.

6.

Associations of Sedentary Behavior and Abdominal Muscle Density: The Multi-Ethnic Study of Atherosclerosis.

Vella CA, Michos ED, Sears DD, Cushman M, Van Hollebeke RB, Wiest MM, Allison MA.

J Phys Act Health. 2018 Nov 1;15(11):827-833. doi: 10.1123/jpah.2018-0028. Epub 2018 Oct 9.

PMID:
30301405
7.

Modeling interrelationships between health behaviors in overweight breast cancer survivors: Applying Bayesian networks.

Xu S, Thompson W, Kerr J, Godbole S, Sears DD, Patterson R, Natarajan L.

PLoS One. 2018 Sep 4;13(9):e0202923. doi: 10.1371/journal.pone.0202923. eCollection 2018.

8.

The Effects of Metformin and Weight Loss on Biomarkers Associated With Breast Cancer Outcomes.

Patterson RE, Marinac CR, Sears DD, Kerr J, Hartman SJ, Cadmus-Bertram L, Villaseñor A, Flatt SW, Godbole S, Li H, Laughlin GA, Oratowski-Coleman J, Parker BA, Natarajan L.

J Natl Cancer Inst. 2018 Nov 1;110(11):1239-1247. doi: 10.1093/jnci/djy040.

9.

AIBP protects against metabolic abnormalities and atherosclerosis.

Schneider DA, Choi SH, Agatisa-Boyle C, Zhu L, Kim J, Pattison J, Sears DD, Gordts PLSM, Fang L, Miller YI.

J Lipid Res. 2018 May;59(5):854-863. doi: 10.1194/jlr.M083618. Epub 2018 Mar 20.

10.

Acute glucoregulatory and vascular outcomes of three strategies for interrupting prolonged sitting time in postmenopausal women: A pilot, laboratory-based, randomized, controlled, 4-condition, 4-period crossover trial.

Kerr J, Crist K, Vital DG, Dillon L, Aden SA, Trivedi M, Castellanos LR, Godbole S, Li H, Allison MA, Khemlina GL, Takemoto ML, Schenk S, Sallis JF, Grace M, Dunstan DW, Natarajan L, LaCroix AZ, Sears DD.

PLoS One. 2017 Nov 30;12(11):e0188544. doi: 10.1371/journal.pone.0188544. eCollection 2017.

11.

Obesity-induced changes in lipid mediators persist after weight loss.

Hernandez-Carretero A, Weber N, La Frano MR, Ying W, Lantero Rodriguez J, Sears DD, Wallenius V, Börgeson E, Newman JW, Osborn O.

Int J Obes (Lond). 2018 Apr;42(4):728-736. doi: 10.1038/ijo.2017.266. Epub 2017 Nov 1.

12.

Randomized controlled trial of increasing physical activity on objectively measured and self-reported cognitive functioning among breast cancer survivors: The memory & motion study.

Hartman SJ, Nelson SH, Myers E, Natarajan L, Sears DD, Palmer BW, Weiner LS, Parker BA, Patterson RE.

Cancer. 2018 Jan 1;124(1):192-202. doi: 10.1002/cncr.30987. Epub 2017 Sep 19.

13.

Metabolic Effects of Intermittent Fasting.

Patterson RE, Sears DD.

Annu Rev Nutr. 2017 Aug 21;37:371-393. doi: 10.1146/annurev-nutr-071816-064634. Epub 2017 Jul 17. Review.

PMID:
28715993
14.

Sedentary Behaviors and Biomarkers Among Breast Cancer Survivors.

Hartman SJ, Marinac CR, Cadmus-Bertram L, Kerr J, Natarajan L, Godbole S, Patterson RE, Morey B, Sears DD.

J Phys Act Health. 2018 Jan 1;15(1):1-6. doi: 10.1123/jpah.2017-0045. Epub 2017 Sep 14.

15.

A prospective study of low fasting glucose with cardiovascular disease events and all-cause mortality: The Women's Health Initiative.

Mongraw-Chaffin M, LaCroix AZ, Sears DD, Garcia L, Phillips LS, Salmoirago-Blotcher E, Zaslavsky O, Anderson CA.

Metabolism. 2017 May;70:116-124. doi: 10.1016/j.metabol.2017.02.010. Epub 2017 Feb 16.

16.

Kernel Density Estimation as a Measure of Environmental Exposure Related to Insulin Resistance in Breast Cancer Survivors.

Jankowska MM, Natarajan L, Godbole S, Meseck K, Sears DD, Patterson RE, Kerr J.

Cancer Epidemiol Biomarkers Prev. 2017 Jul;26(7):1078-1084. doi: 10.1158/1055-9965.EPI-16-0927. Epub 2017 Mar 3.

17.

Time-restricted feeding improves insulin resistance and hepatic steatosis in a mouse model of postmenopausal obesity.

Chung H, Chou W, Sears DD, Patterson RE, Webster NJ, Ellies LG.

Metabolism. 2016 Dec;65(12):1743-1754. doi: 10.1016/j.metabol.2016.09.006. Epub 2016 Sep 22.

18.

Circulating adipocyte-derived extracellular vesicles are novel markers of metabolic stress.

Eguchi A, Lazic M, Armando AM, Phillips SA, Katebian R, Maraka S, Quehenberger O, Sears DD, Feldstein AE.

J Mol Med (Berl). 2016 Nov;94(11):1241-1253. doi: 10.1007/s00109-016-1446-8. Epub 2016 Jul 9.

19.

Prolonged Nightly Fasting and Breast Cancer Prognosis.

Marinac CR, Nelson SH, Breen CI, Hartman SJ, Natarajan L, Pierce JP, Flatt SW, Sears DD, Patterson RE.

JAMA Oncol. 2016 Aug 1;2(8):1049-55. doi: 10.1001/jamaoncol.2016.0164.

20.

Impact of increasing physical activity on cognitive functioning in breast cancer survivors: Rationale and study design of Memory & Motion.

Hartman SJ, Natarajan L, Palmer BW, Parker B, Patterson RE, Sears DD.

Contemp Clin Trials. 2015 Nov;45(Pt B):371-376. doi: 10.1016/j.cct.2015.09.021. Epub 2015 Sep 30.

21.

Frequency and Circadian Timing of Eating May Influence Biomarkers of Inflammation and Insulin Resistance Associated with Breast Cancer Risk.

Marinac CR, Sears DD, Natarajan L, Gallo LC, Breen CI, Patterson RE.

PLoS One. 2015 Aug 25;10(8):e0136240. doi: 10.1371/journal.pone.0136240. eCollection 2015.

22.

Gender and Age Differences in Hourly and Daily Patterns of Sedentary Time in Older Adults Living in Retirement Communities.

Bellettiere J, Carlson JA, Rosenberg D, Singhania A, Natarajan L, Berardi V, LaCroix AZ, Sears DD, Moran K, Crist K, Kerr J.

PLoS One. 2015 Aug 21;10(8):e0136161. doi: 10.1371/journal.pone.0136161. eCollection 2015.

23.

Prolonged Nightly Fasting and Breast Cancer Risk: Findings from NHANES (2009-2010).

Marinac CR, Natarajan L, Sears DD, Gallo LC, Hartman SJ, Arredondo E, Patterson RE.

Cancer Epidemiol Biomarkers Prev. 2015 May;24(5):783-9. doi: 10.1158/1055-9965.EPI-14-1292. Epub 2015 Apr 20.

24.

Intermittent Fasting and Human Metabolic Health.

Patterson RE, Laughlin GA, LaCroix AZ, Hartman SJ, Natarajan L, Senger CM, Martínez ME, Villaseñor A, Sears DD, Marinac CR, Gallo LC.

J Acad Nutr Diet. 2015 Aug;115(8):1203-12. doi: 10.1016/j.jand.2015.02.018. Epub 2015 Apr 6. No abstract available.

25.

Evaluation of the synuclein-γ (SNCG) gene as a PPARγ target in murine adipocytes, dorsal root ganglia somatosensory neurons, and human adipose tissue.

Dunn TN, Akiyama T, Lee HW, Kim JB, Knotts TA, Smith SR, Sears DD, Carstens E, Adams SH.

PLoS One. 2015 Mar 10;10(3):e0115830. doi: 10.1371/journal.pone.0115830. eCollection 2015.

26.

Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis.

Lazic M, Inzaugarat ME, Povero D, Zhao IC, Chen M, Nalbandian M, Miller YI, Cherñavsky AC, Feldstein AE, Sears DD.

PLoS One. 2014 Sep 24;9(9):e107658. doi: 10.1371/journal.pone.0107658. eCollection 2014.

27.

Omega-3 fatty acids reduce obesity-induced tumor progression independent of GPR120 in a mouse model of postmenopausal breast cancer.

Chung H, Lee YS, Mayoral R, Oh DY, Siu JT, Webster NJ, Sears DD, Olefsky JM, Ellies LG.

Oncogene. 2015 Jul;34(27):3504-13. doi: 10.1038/onc.2014.283. Epub 2014 Sep 15.

28.

TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis.

Inokuchi-Shimizu S, Park EJ, Roh YS, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, Asahina K, Lagakos W, Mackey MR, Akira S, Ellisman MH, Sears DD, Olefsky JM, Karin M, Brenner DA, Seki E.

J Clin Invest. 2014 Aug;124(8):3566-78. doi: 10.1172/JCI74068. Epub 2014 Jul 1.

29.

Macrophage glucose-6-phosphate dehydrogenase stimulates proinflammatory responses with oxidative stress.

Ham M, Lee JW, Choi AH, Jang H, Choi G, Park J, Kozuka C, Sears DD, Masuzaki H, Kim JB.

Mol Cell Biol. 2013 Jun;33(12):2425-35. doi: 10.1128/MCB.01260-12. Epub 2013 Apr 9.

30.

The 2011-2016 Transdisciplinary Research on Energetics and Cancer (TREC) initiative: rationale and design.

Patterson RE, Colditz GA, Hu FB, Schmitz KH, Ahima RS, Brownson RC, Carson KR, Chavarro JE, Chodosh LA, Gehlert S, Gill J, Glanz K, Haire-Joshu D, Herbst KL, Hoehner CM, Hovmand PS, Irwin ML, Jacobs LA, James AS, Jones LW, Kerr J, Kibel AS, King IB, Ligibel JA, Meyerhardt JA, Natarajan L, Neuhouser ML, Olefsky JM, Proctor EK, Redline S, Rock CL, Rosner B, Sarwer DB, Schwartz JS, Sears DD, Sesso HD, Stampfer MJ, Subramanian SV, Taveras EM, Tchou J, Thompson B, Troxel AB, Wessling-Resnick M, Wolin KY, Thornquist MD.

Cancer Causes Control. 2013 Apr;24(4):695-704. doi: 10.1007/s10552-013-0150-z. Epub 2013 Feb 3.

31.

Inverse regulation of inflammation and mitochondrial function in adipose tissue defines extreme insulin sensitivity in morbidly obese patients.

Qatanani M, Tan Y, Dobrin R, Greenawalt DM, Hu G, Zhao W, Olefsky JM, Sears DD, Kaplan LM, Kemp DM.

Diabetes. 2013 Mar;62(3):855-63. doi: 10.2337/db12-0399. Epub 2012 Dec 6.

32.

SirT1 regulates adipose tissue inflammation.

Gillum MP, Kotas ME, Erion DM, Kursawe R, Chatterjee P, Nead KT, Muise ES, Hsiao JJ, Frederick DW, Yonemitsu S, Banks AS, Qiang L, Bhanot S, Olefsky JM, Sears DD, Caprio S, Shulman GI.

Diabetes. 2011 Dec;60(12):3235-45. doi: 10.2337/db11-0616.

33.

Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity.

Li P, Fan W, Xu J, Lu M, Yamamoto H, Auwerx J, Sears DD, Talukdar S, Oh D, Chen A, Bandyopadhyay G, Scadeng M, Ofrecio JM, Nalbandian S, Olefsky JM.

Cell. 2011 Nov 11;147(4):815-26. doi: 10.1016/j.cell.2011.09.050.

34.

Fat-induced inflammation unchecked.

Osborn O, Sears DD, Olefsky JM.

Cell Metab. 2010 Dec 1;12(6):553-4. doi: 10.1016/j.cmet.2010.11.017.

35.

Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice.

Chapman J, Miles PD, Ofrecio JM, Neels JG, Yu JG, Resnik JL, Wilkes J, Talukdar S, Thapar D, Johnson K, Sears DD.

PLoS One. 2010 Nov 12;5(11):e13959. doi: 10.1371/journal.pone.0013959.

36.

Multi-tissue, selective PPARγ modulation of insulin sensitivity and metabolic pathways in obese rats.

Hsiao G, Chapman J, Ofrecio JM, Wilkes J, Resnik JL, Thapar D, Subramaniam S, Sears DD.

Am J Physiol Endocrinol Metab. 2011 Jan;300(1):E164-74. doi: 10.1152/ajpendo.00219.2010. Epub 2010 Oct 19.

37.

TLR4 and Insulin Resistance.

Kim JJ, Sears DD.

Gastroenterol Res Pract. 2010;2010. pii: 212563. doi: 10.1155/2010/212563. Epub 2010 Aug 10.

38.

Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice.

Li P, Lu M, Nguyen MT, Bae EJ, Chapman J, Feng D, Hawkins M, Pessin JE, Sears DD, Nguyen AK, Amidi A, Watkins SM, Nguyen U, Olefsky JM.

J Biol Chem. 2010 May 14;285(20):15333-45. doi: 10.1074/jbc.M110.100263. Epub 2010 Mar 22.

39.

PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization.

Sugii S, Olson P, Sears DD, Saberi M, Atkins AR, Barish GD, Hong SH, Castro GL, Yin YQ, Nelson MC, Hsiao G, Greaves DR, Downes M, Yu RT, Olefsky JM, Evans RM.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22504-9. doi: 10.1073/pnas.0912487106. Epub 2009 Dec 16.

40.

Mechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization.

Sears DD, Hsiao G, Hsiao A, Yu JG, Courtney CH, Ofrecio JM, Chapman J, Subramaniam S.

Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18745-50. doi: 10.1073/pnas.0903032106. Epub 2009 Oct 19.

41.

12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice.

Sears DD, Miles PD, Chapman J, Ofrecio JM, Almazan F, Thapar D, Miller YI.

PLoS One. 2009 Sep 29;4(9):e7250. doi: 10.1371/journal.pone.0007250.

42.

MBX-102/JNJ39659100, a novel peroxisome proliferator-activated receptor-ligand with weak transactivation activity retains antidiabetic properties in the absence of weight gain and edema.

Gregoire FM, Zhang F, Clarke HJ, Gustafson TA, Sears DD, Favelyukis S, Lenhard J, Rentzeperis D, Clemens LE, Mu Y, Lavan BE.

Mol Endocrinol. 2009 Jul;23(7):975-88. doi: 10.1210/me.2008-0473. Epub 2009 Apr 23.

43.

FOXO1 transrepresses peroxisome proliferator-activated receptor gamma transactivation, coordinating an insulin-induced feed-forward response in adipocytes.

Fan W, Imamura T, Sonoda N, Sears DD, Patsouris D, Kim JJ, Olefsky JM.

J Biol Chem. 2009 May 1;284(18):12188-97. doi: 10.1074/jbc.M808915200. Epub 2009 Feb 26.

44.

Molecular Characterization of the Tumor Suppressor Candidate 5 Gene: Regulation by PPARgamma and Identification of TUSC5 Coding Variants in Lean and Obese Humans.

Knotts TA, Lee HW, Kim JB, Oort PJ, McPherson R, Dent R, Tachibana K, Doi T, Yu S, Reddy JK, Uno K, Katagiri H, Pasarica M, Smith SR, Sears DD, Grino M, Adams SH.

PPAR Res. 2009;2009:867678. doi: 10.1155/2009/867678. Epub 2010 Mar 1.

45.

Selective modulation of promoter recruitment and transcriptional activity of PPARgamma.

Sears DD, Hsiao A, Ofrecio JM, Chapman J, He W, Olefsky JM.

Biochem Biophys Res Commun. 2007 Dec 21;364(3):515-21. Epub 2007 Oct 18.

46.

Increased instability of human CTG repeat tracts on yeast artificial chromosomes during gametogenesis.

Cohen H, Sears DD, Zenvirth D, Hieter P, Simchen G.

Mol Cell Biol. 1999 Jun;19(6):4153-8.

49.

Alu sequences in RMSA-1 protein?

Tugendreich S, Feng Q, Kroll J, Sears DD, Boeke JD, Hieter P.

Nature. 1994 Jul 14;370(6485):106. No abstract available.

PMID:
8022478
50.

Meiotic recombination and segregation of human-derived artificial chromosomes in Saccharomyces cerevisiae.

Sears DD, Hegemann JH, Hieter P.

Proc Natl Acad Sci U S A. 1992 Jun 15;89(12):5296-300.

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