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Items: 43

1.

Lessons from the CAGI-4 Hopkins clinical panel challenge.

Chandonia JM, Adhikari A, Carraro M, Chhibber A, Cutting GR, Fu Y, Gasparini A, Jones DT, Kramer A, Kundu K, Lam HYK, Leonardi E, Moult J, Pal LR, Searls DB, Shah S, Sunyaev S, Tosatto SCE, Yin Y, Buckley BA.

Hum Mutat. 2017 Sep;38(9):1155-1168. doi: 10.1002/humu.23225. Epub 2017 Jun 12.

2.

A new online computational biology curriculum.

Searls DB.

PLoS Comput Biol. 2014 Jun 12;10(6):e1003662. doi: 10.1371/journal.pcbi.1003662. eCollection 2014 Jun.

3.

A primer in macromolecular linguistics.

Searls DB.

Biopolymers. 2013 Mar;99(3):203-17. doi: 10.1002/bip.22101. Epub 2012 Oct 3. Review.

PMID:
23034580
4.

An online bioinformatics curriculum.

Searls DB.

PLoS Comput Biol. 2012;8(9):e1002632. doi: 10.1371/journal.pcbi.1002632. Epub 2012 Sep 13.

5.

Ten simple rules for online learning.

Searls DB.

PLoS Comput Biol. 2012;8(9):e1002631. doi: 10.1371/journal.pcbi.1002631. Epub 2012 Sep 13. No abstract available.

6.

The roots of bioinformatics.

Searls DB.

PLoS Comput Biol. 2010 Jun 24;6(6):e1000809. doi: 10.1371/journal.pcbi.1000809. No abstract available.

7.

Can literature analysis identify innovation drivers in drug discovery?

Agarwal P, Searls DB.

Nat Rev Drug Discov. 2009 Nov;8(11):865-78. doi: 10.1038/nrd2973. Review.

PMID:
19876041
8.

Ten simple rules for choosing between industry and academia.

Searls DB.

PLoS Comput Biol. 2009 Jun;5(6):e1000388. doi: 10.1371/journal.pcbi.1000388. Epub 2009 Jun 26. No abstract available.

9.

Omic empiricism.

Searls DB.

Sci Signal. 2009 Apr 28;2(68):eg6. doi: 10.1126/scisignal.268eg6. No abstract available.

10.

IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels.

Harmar AJ, Hills RA, Rosser EM, Jones M, Buneman OP, Dunbar DR, Greenhill SD, Hale VA, Sharman JL, Bonner TI, Catterall WA, Davenport AP, Delagrange P, Dollery CT, Foord SM, Gutman GA, Laudet V, Neubig RR, Ohlstein EH, Olsen RW, Peters J, Pin JP, Ruffolo RR, Searls DB, Wright MW, Spedding M.

Nucleic Acids Res. 2009 Jan;37(Database issue):D680-5. doi: 10.1093/nar/gkn728. Epub 2008 Oct 23.

11.

Literature mining in support of drug discovery.

Agarwal P, Searls DB.

Brief Bioinform. 2008 Nov;9(6):479-92. doi: 10.1093/bib/bbn035. Epub 2008 Sep 27. Review.

PMID:
18820304
12.

A view from the dark side.

Searls DB.

PLoS Comput Biol. 2007 Jun;3(6):e105. No abstract available.

13.

Risk in drug trials.

Barnes MR, Holbrook J, Feild JA, Searls DB, Sanseau P.

Lancet. 2006 Dec 23;368(9554):2205. No abstract available.

PMID:
17189021
14.

Grammatical representations of macromolecular structure.

Chiang D, Joshi AK, Searls DB.

J Comput Biol. 2006 Jun;13(5):1077-100.

PMID:
16796552
15.

Clusters of adjacent and similarly expressed genes across normal human tissues complicate comparative transcriptomic discovery.

Liu C, Ghosh S, Searls DB, Saunders AM, Cossman J, Roses AD.

OMICS. 2005 Winter;9(4):351-63.

PMID:
16402893
16.

Managing genomic and proteomic knowledge.

Lutz MW, Warren PV, Gill RW, Searls DB.

Drug Discov Today Technol. 2005 Autumn;2(3):197-204. doi: 10.1016/j.ddtec.2005.08.001.

PMID:
24981936
17.

Data integration: challenges for drug discovery.

Searls DB.

Nat Rev Drug Discov. 2005 Jan;4(1):45-58. Review.

PMID:
15688072
18.

Linguistics: trees of life and of language.

Searls DB.

Nature. 2003 Nov 27;426(6965):391-2. No abstract available.

PMID:
14647362
19.

Pharmacophylogenomics: genes, evolution and drug targets.

Searls DB.

Nat Rev Drug Discov. 2003 Aug;2(8):613-23. Review. No abstract available.

PMID:
12904811
20.

Data integration--connecting the dots.

Searls DB.

Nat Biotechnol. 2003 Aug;21(8):844-5. No abstract available.

PMID:
12894190
21.

The language of genes.

Searls DB.

Nature. 2002 Nov 14;420(6912):211-7. Review.

PMID:
12432405
22.

Mining the bibliome.

Searls DB.

Pharmacogenomics J. 2001;1(2):88-9. No abstract available.

PMID:
11911444
23.

Bioinformatics tools for whole genomes.

Searls DB.

Annu Rev Genomics Hum Genet. 2000;1:251-79. Review.

PMID:
11701631
24.

From Jabberwocky to genome: Lewis Carroll and computational biology.

Searls DB.

J Comput Biol. 2001;8(3):339-48.

PMID:
11535180
25.

Reading the book of life.

Searls DB.

Bioinformatics. 2001 Jul;17(7):579-80. No abstract available.

PMID:
11448875
26.

Using bioinformatics in gene and drug discovery.

Searls DB.

Drug Discov Today. 2000 Apr;5(4):135-143.

PMID:
10729819
27.

Analysis of EST-driven gene annotation in human genomic sequence.

Bailey LC Jr, Searls DB, Overton GC.

Genome Res. 1998 Apr;8(4):362-76.

28.

Linguistic approaches to biological sequences.

Searls DB.

Comput Appl Biosci. 1997 Aug;13(4):333-44. Review.

PMID:
9283748
29.

Computational gene discovery and human disease.

Rawlings CJ, Searls DB.

Curr Opin Genet Dev. 1997 Jun;7(3):416-23. Review.

PMID:
9229120
30.

Sequence alignment through pictures.

Searls DB.

Trends Genet. 1996 Jan;12(1):35-7. No abstract available.

PMID:
8741859
31.

bioTk:componentry for genome informatics graphical user interfaces.

Searls DB.

Gene. 1995 Oct 3;163(2):GC1-16.

PMID:
7590260
32.

Automata-theoretic models of mutation and alignment.

Searls DB, Murphy KP.

Proc Int Conf Intell Syst Mol Biol. 1995;3:341-9.

PMID:
7584457
33.

Gene structure prediction by linguistic methods.

Dong S, Searls DB.

Genomics. 1994 Oct;23(3):540-51.

PMID:
7851881
34.

SORTEZ: a relational translator for NCBI's ASN.1 database.

Hart KW, Searls DB, Overton GC.

Comput Appl Biosci. 1994 Jul;10(4):369-78.

PMID:
7804870
35.

Doing sequence analysis with your printer.

Searls DB.

Comput Appl Biosci. 1993 Aug;9(4):421-6.

PMID:
8402209
36.

Fast Fourier transform-based correlation of DNA sequences using complex plane encoding.

Cheever EA, Overton GC, Searls DB.

Comput Appl Biosci. 1991 Apr;7(2):143-54.

PMID:
2059838
37.

Chromosomal site of hepatitis B virus (HBV) integration in a human hepatocellular carcinoma-derived cell line.

Simon D, Searls DB, Cao Y, Sun K, Knowles BB.

Cytogenet Cell Genet. 1985;39(2):116-20.

PMID:
2988862
38.

Hybridization with a teratocarcinoma-derived cell line confers resistance to cell-mediated inhibition of growth on L cells.

Fenderson BA, Searls DB.

Transplantation. 1983 Jul;36(1):112-3. No abstract available.

PMID:
6603038
39.

H-2 expression on a teratocarcinoma-derived cell line, TerC.

Searls DB, Edidin M.

J Natl Cancer Inst. 1982 Dec;69(6):1311-5.

PMID:
6958907
40.
41.
42.

Plasma membrane isolation on DEAE-Sephadex beads.

Gotlib LJ, Searls DB.

Biochim Biophys Acta. 1980 Oct 16;602(1):207-12.

PMID:
7417448
43.

An improved colorimetric assay for plasminogen activator.

Searls DB.

Anal Biochem. 1980 Sep 1;107(1):64-70. No abstract available.

PMID:
7192061

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