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Items: 1 to 20 of 102

1.

Genomic landscape of neutrophilic leukemias of ambiguous diagnosis.

Zhang H, Wilmot B, Bottomly D, Dao KT, Stevens E, Eide CA, Khanna V, Rofelty A, Savage S, Reister Schultz A, Long N, White L, Carlos A, Henson R, Lin C, Searles R, Collins RH, DeAngelo DJ, Deininger MW, Dunn T, Hein T, Luskin MR, Medeiros BC, Oh ST, Pollyea DA, Steensma DP, Stone RM, Druker BJ, McWeeney SK, Maxson JE, Gotlib JR, Tyner JW.

Blood. 2019 Sep 12;134(11):867-879. doi: 10.1182/blood.2019000611. Epub 2019 Jul 31.

PMID:
31366621
2.

Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms.

Zhang H, Savage S, Schultz AR, Bottomly D, White L, Segerdell E, Wilmot B, McWeeney SK, Eide CA, Nechiporuk T, Carlos A, Henson R, Lin C, Searles R, Ho H, Lam YL, Sweat R, Follit C, Jain V, Lind E, Borthakur G, Garcia-Manero G, Ravandi F, Kantarjian HM, Cortes J, Collins R, Buelow DR, Baker SD, Druker BJ, Tyner JW.

Nat Commun. 2019 Jan 16;10(1):244. doi: 10.1038/s41467-018-08263-x.

3.

Functional genomic landscape of acute myeloid leukaemia.

Tyner JW, Tognon CE, Bottomly D, Wilmot B, Kurtz SE, Savage SL, Long N, Schultz AR, Traer E, Abel M, Agarwal A, Blucher A, Borate U, Bryant J, Burke R, Carlos A, Carpenter R, Carroll J, Chang BH, Coblentz C, d'Almeida A, Cook R, Danilov A, Dao KT, Degnin M, Devine D, Dibb J, Edwards DK 5th, Eide CA, English I, Glover J, Henson R, Ho H, Jemal A, Johnson K, Johnson R, Junio B, Kaempf A, Leonard J, Lin C, Liu SQ, Lo P, Loriaux MM, Luty S, Macey T, MacManiman J, Martinez J, Mori M, Nelson D, Nichols C, Peters J, Ramsdill J, Rofelty A, Schuff R, Searles R, Segerdell E, Smith RL, Spurgeon SE, Sweeney T, Thapa A, Visser C, Wagner J, Watanabe-Smith K, Werth K, Wolf J, White L, Yates A, Zhang H, Cogle CR, Collins RH, Connolly DC, Deininger MW, Drusbosky L, Hourigan CS, Jordan CT, Kropf P, Lin TL, Martinez ME, Medeiros BC, Pallapati RR, Pollyea DA, Swords RT, Watts JM, Weir SJ, Wiest DL, Winters RM, McWeeney SK, Druker BJ.

Nature. 2018 Oct;562(7728):526-531. doi: 10.1038/s41586-018-0623-z. Epub 2018 Oct 17.

4.

Cross-species molecular dissection across alcohol behavioral domains.

Farris SP, Riley BP, Williams RW, Mulligan MK, Miles MF, Lopez MF, Hitzemann R, Iancu OD, Colville A, Walter NAR, Darakjian P, Oberbeck DL, Daunais JB, Zheng CL, Searles RP, McWeeney SK, Grant KA, Mayfield RD.

Alcohol. 2018 Nov;72:19-31. doi: 10.1016/j.alcohol.2017.11.036. Epub 2017 Dec 6. Review.

5.

Regional Differences and Similarities in the Brain Transcriptome for Mice Selected for Ethanol Preference From HS-CC Founders.

Colville AM, Iancu OD, Lockwood DR, Darakjian P, McWeeney SK, Searles R, Zheng C, Hitzemann R.

Front Genet. 2018 Aug 28;9:300. doi: 10.3389/fgene.2018.00300. eCollection 2018.

6.

Gender-Specific Effects of Selection for Drinking in the Dark on the Network Roles of Coding and Noncoding RNAs.

Iancu OD, Colville AM, Wilmot B, Searles R, Darakjian P, Zheng C, McWeeney S, Kawane S, Crabbe JC, Metten P, Oberbeck D, Hitzemann R.

Alcohol Clin Exp Res. 2018 Aug;42(8):1454-1465. doi: 10.1111/acer.13777. Epub 2018 Jun 22.

7.

On the relationships in rhesus macaques between chronic ethanol consumption and the brain transcriptome.

Iancu OD, Colville A, Walter NAR, Darakjian P, Oberbeck DL, Daunais JB, Zheng CL, Searles RP, McWeeney SK, Grant KA, Hitzemann R.

Addict Biol. 2018 Jan;23(1):196-205. doi: 10.1111/adb.12501. Epub 2017 Feb 28.

8.

Effects of selection for ethanol preference on gene expression in the nucleus accumbens of HS-CC mice.

Colville AM, Iancu OD, Oberbeck DL, Darakjian P, Zheng CL, Walter NA, Harrington CA, Searles RP, McWeeney S, Hitzemann RJ.

Genes Brain Behav. 2017 Apr;16(4):462-471. doi: 10.1111/gbb.12367. Epub 2017 Feb 9.

9.

A Subset of Malignant Mesothelioma Tumors Retain Osteogenic Potential.

Lansley SM, Pedersen B, Robinson C, Searles RG, Sterrett G, van Bruggen I, Lake RA, Mutsaers SE, Prêle CM.

Sci Rep. 2016 Nov 25;6:36349. doi: 10.1038/srep36349.

10.

Anti-Müllerian hormone is produced heterogeneously in primate preantral follicles and is a potential biomarker for follicle growth and oocyte maturation in vitro.

Xu J, Xu F, Letaw JH, Park BS, Searles RP, Ferguson BM.

J Assist Reprod Genet. 2016 Dec;33(12):1665-1675. Epub 2016 Sep 15.

11.

Splicing landscape of the eight collaborative cross founder strains.

Zheng CL, Wilmot B, Walter NA, Oberbeck D, Kawane S, Searles RP, McWeeney SK, Hitzemann R.

BMC Genomics. 2015 Feb 5;16:52. doi: 10.1186/s12864-015-1267-0.

12.

Introduction to sequencing the brain transcriptome.

Hitzemann R, Darakjian P, Walter N, Iancu OD, Searles R, McWeeney S.

Int Rev Neurobiol. 2014;116:1-19. doi: 10.1016/B978-0-12-801105-8.00001-1. Review.

13.

The genetics of gene expression in complex mouse crosses as a tool to study the molecular underpinnings of behavior traits.

Hitzemann R, Bottomly D, Iancu O, Buck K, Wilmot B, Mooney M, Searles R, Zheng C, Belknap J, Crabbe J, McWeeney S.

Mamm Genome. 2014 Feb;25(1-2):12-22. doi: 10.1007/s00335-013-9495-6. Epub 2013 Dec 31. Review.

14.

Loss of the nuclear receptor corepressor SLIRP compromises male fertility.

Colley SM, Wintle L, Searles R, Russell V, Firman RC, Smith S, Deboer K, Merriner DJ, Genevieve B, Bentel JM, Stuckey BG, Phillips MR, Simmons LW, de Kretser DM, O'Bryan MK, Leedman PJ.

PLoS One. 2013 Aug 15;8(8):e70700. doi: 10.1371/journal.pone.0070700. eCollection 2013.

15.

Genes, behavior and next-generation RNA sequencing.

Hitzemann R, Bottomly D, Darakjian P, Walter N, Iancu O, Searles R, Wilmot B, McWeeney S.

Genes Brain Behav. 2013 Feb;12(1):1-12. doi: 10.1111/gbb.12007. Epub 2012 Dec 28. Review.

16.

Utilizing RNA-Seq data for de novo coexpression network inference.

Iancu OD, Kawane S, Bottomly D, Searles R, Hitzemann R, McWeeney S.

Bioinformatics. 2012 Jun 15;28(12):1592-7. doi: 10.1093/bioinformatics/bts245. Epub 2012 May 3.

17.

Evaluating gene expression in C57BL/6J and DBA/2J mouse striatum using RNA-Seq and microarrays.

Bottomly D, Walter NA, Hunter JE, Darakjian P, Kawane S, Buck KJ, Searles RP, Mooney M, McWeeney SK, Hitzemann R.

PLoS One. 2011 Mar 24;6(3):e17820. doi: 10.1371/journal.pone.0017820.

18.

Mesothelial cell differentiation into osteoblast- and adipocyte-like cells.

Lansley SM, Searles RG, Hoi A, Thomas C, Moneta H, Herrick SE, Thompson PJ, Newman M, Sterrett GF, Prêle CM, Mutsaers SE.

J Cell Mol Med. 2011 Oct;15(10):2095-105. doi: 10.1111/j.1582-4934.2010.01212.x.

19.

Nos3 protects against systemic inflammation and myocardial dysfunction in murine polymicrobial sepsis.

Bougaki M, Searles RJ, Kida K, Yu J, Buys ES, Ichinose F.

Shock. 2010 Sep;34(3):281-90. doi: 10.1097/SHK.0b013e3181cdc327.

20.

Novel nuclear nesprin-2 variants tether active extracellular signal-regulated MAPK1 and MAPK2 at promyelocytic leukemia protein nuclear bodies and act to regulate smooth muscle cell proliferation.

Warren DT, Tajsic T, Mellad JA, Searles R, Zhang Q, Shanahan CM.

J Biol Chem. 2010 Jan 8;285(2):1311-20. doi: 10.1074/jbc.M109.032557. Epub 2009 Oct 27.

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