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Items: 17


Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota.

Wu RY, Määttänen P, Napper S, Scruten E, Li B, Koike Y, Johnson-Henry KC, Pierro A, Rossi L, Botts SR, Surette MG, Sherman PM.

Microbiome. 2017 Oct 10;5(1):135. doi: 10.1186/s40168-017-0357-4.


Induction of PrPSc-specific systemic and mucosal immune responses in white-tailed deer with an oral vaccine for chronic wasting disease.

Taschuk R, Scruten E, Woodbury M, Cashman N, Potter A, Griebel P, Tikoo SK, Napper S.

Prion. 2017 Sep 3;11(5):368-380. doi: 10.1080/19336896.2017.1367083.


Protein kinase C δ signaling is required for dietary prebiotic-induced strengthening of intestinal epithelial barrier function.

Wu RY, Abdullah M, Määttänen P, Pilar AV, Scruten E, Johnson-Henry KC, Napper S, O'Brien C, Jones NL, Sherman PM.

Sci Rep. 2017 Jan 18;7:40820. doi: 10.1038/srep40820.


Induction of functional interferon alpha and gamma responses during acute infection of cattle with non-cytopathic bovine viral diarrhea virus.

Van Wyk B, Snider M, Scruten E, van Drunen Littel-van den Hurk S, Napper S.

Vet Microbiol. 2016 Nov 15;195:104-114. doi: 10.1016/j.vetmic.2016.09.015. Epub 2016 Sep 22.


Investigation of the physiological, behavioral, and biochemical responses of cattle to restraint stress.

Chen Y, Stookey J, Arsenault R, Scruten E, Griebel P, Napper S.

J Anim Sci. 2016 Aug;94(8):3240-3254.


Induction of tissue- and stressor-specific kinomic responses in chickens exposed to hot and cold stresses.

Napper S, Dadgar S, Arsenault RJ, Trost B, Scruten E, Kusalik A, Shand P.

Poult Sci. 2015 Jun;94(6):1333-45. doi: 10.3382/ps/pev046. Epub 2015 Apr 1.


Identification of developmentally-specific kinotypes and mechanisms of Varroa mite resistance through whole-organism, kinome analysis of honeybee.

Robertson AJ, Trost B, Scruten E, Robertson T, Mostajeran M, Connor W, Kusalik A, Griebel P, Napper S.

Front Genet. 2014 May 21;5:139. doi: 10.3389/fgene.2014.00139. eCollection 2014.


Peptide Arrays for Kinome Analysis of Livestock Species.

Daigle J, Van Wyk B, Trost B, Scruten E, Arsenault R, Kusalik A, Griebel PJ, Napper S.

Front Vet Sci. 2014 Oct 14;1:4. doi: 10.3389/fvets.2014.00004. eCollection 2014. Review.


Kinotypes: stable species- and individual-specific profiles of cellular kinase activity.

Trost B, Kindrachuk J, Scruten E, Griebel P, Kusalik A, Napper S.

BMC Genomics. 2013 Dec 5;14:854. doi: 10.1186/1471-2164-14-854.


In vitro infection of bovine monocytes with Mycoplasma bovis delays apoptosis and suppresses production of gamma interferon and tumor necrosis factor alpha but not interleukin-10.

Mulongo M, Prysliak T, Scruten E, Napper S, Perez-Casal J.

Infect Immun. 2014 Jan;82(1):62-71. doi: 10.1128/IAI.00961-13. Epub 2013 Oct 14.


Divergent immune responses to Mycobacterium avium subsp. paratuberculosis infection correlate with kinome responses at the site of intestinal infection.

Määttänen P, Trost B, Scruten E, Potter A, Kusalik A, Griebel P, Napper S.

Infect Immun. 2013 Aug;81(8):2861-72. doi: 10.1128/IAI.00339-13. Epub 2013 May 28.


Host responses to persistent Mycobacterium avium subspecies paratuberculosis infection in surgically isolated bovine ileal segments.

Charavaryamath C, Gonzalez-Cano P, Fries P, Gomis S, Doig K, Scruten E, Potter A, Napper S, Griebel PJ.

Clin Vaccine Immunol. 2013 Feb;20(2):156-65. doi: 10.1128/CVI.00496-12. Epub 2012 Dec 5.


Altered Toll-like receptor 9 signaling in Mycobacterium avium subsp. paratuberculosis-infected bovine monocytes reveals potential therapeutic targets.

Arsenault RJ, Li Y, Maattanen P, Scruten E, Doig K, Potter A, Griebel P, Kusalik A, Napper S.

Infect Immun. 2013 Jan;81(1):226-37. doi: 10.1128/IAI.00785-12. Epub 2012 Oct 31.


Stability, toxicity and biological activity of retro, inversed and retro-inversed glucagon isomers.

Krasniqi B, Scruten E, Piller J, Lee J, Napper S.

J Pept Sci. 2012 Aug;18(8):519-26. doi: 10.1002/psc.2429. Epub 2012 Jul 3.


Stability, toxicity, and biological activity of host defense peptide BMAP28 and its inversed and retro-inversed isomers.

Kindrachuk J, Scruten E, Attah-Poku S, Bell K, Potter A, Babiuk LA, Griebel PJ, Napper S.

Biopolymers. 2011;96(1):14-24. doi: 10.1002/bip.21441.


Retro-inversion enhances the adjuvant and CpG co-adjuvant activity of host defence peptide Bac2A.

Scruten E, Kovacs-Nolan J, Griebel PJ, Latimer L, Kindrachuk J, Potter A, Babiuk LA, Littel-van den Hurk Sv, Napper S.

Vaccine. 2010 Apr 9;28(17):2945-56. doi: 10.1016/j.vaccine.2010.02.015. Epub 2010 Mar 1.


The PhoQ-activating potential of antimicrobial peptides contributes to antimicrobial efficacy and is predictive of the induction of bacterial resistance.

Kindrachuk J, Paur N, Reiman C, Scruten E, Napper S.

Antimicrob Agents Chemother. 2007 Dec;51(12):4374-81. Epub 2007 Oct 15.

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