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Items: 33

1.

Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition.

Hemming ML, Lawlor MA, Andersen JL, Hagan T, Chipashvili O, Scott TG, Raut CP, Sicinska E, Armstrong SA, Demetri GD, Bradner JE.

Cancer Res. 2019 Jan 10. pii: canres.1888.2018. doi: 10.1158/0008-5472.CAN-18-1888. [Epub ahead of print]

PMID:
30630822
2.

The dTAG system for immediate and target-specific protein degradation.

Nabet B, Roberts JM, Buckley DL, Paulk J, Dastjerdi S, Yang A, Leggett AL, Erb MA, Lawlor MA, Souza A, Scott TG, Vittori S, Perry JA, Qi J, Winter GE, Wong KK, Gray NS, Bradner JE.

Nat Chem Biol. 2018 May;14(5):431-441. doi: 10.1038/s41589-018-0021-8. Epub 2018 Mar 26.

3.

Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands.

Gechijian LN, Buckley DL, Lawlor MA, Reyes JM, Paulk J, Ott CJ, Winter GE, Erb MA, Scott TG, Xu M, Seo HS, Dhe-Paganon S, Kwiatkowski NP, Perry JA, Qi J, Gray NS, Bradner JE.

Nat Chem Biol. 2018 Apr;14(4):405-412. doi: 10.1038/s41589-018-0010-y. Epub 2018 Mar 5.

4.

Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma.

Zeid R, Lawlor MA, Poon E, Reyes JM, Fulciniti M, Lopez MA, Scott TG, Nabet B, Erb MA, Winter GE, Jacobson Z, Polaski DR, Karlin KL, Hirsch RA, Munshi NP, Westbrook TF, Chesler L, Lin CY, Bradner JE.

Nat Genet. 2018 Apr;50(4):515-523. doi: 10.1038/s41588-018-0044-9. Epub 2018 Jan 29.

5.

Correction to BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen.

Ayoub AM, Hawk LML, Herzig RJ, Jiang J, Wisniewski AJ, Gee CT, Zhao P, Zhu JY, Berndt N, Offei-Addo NK, Scott TG, Qi J, Bradner JE, Ward TR, Schönbrunn E, Georg GI, Pomerantz WCK.

J Med Chem. 2017 Jul 27;60(14):6458. doi: 10.1021/acs.jmedchem.7b00943. Epub 2017 Jul 11. No abstract available.

PMID:
28696689
6.

BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment.

Winter GE, Mayer A, Buckley DL, Erb MA, Roderick JE, Vittori S, Reyes JM, di Iulio J, Souza A, Ott CJ, Roberts JM, Zeid R, Scott TG, Paulk J, Lachance K, Olson CM, Dastjerdi S, Bauer S, Lin CY, Gray NS, Kelliher MA, Churchman LS, Bradner JE.

Mol Cell. 2017 Jul 6;67(1):5-18.e19. doi: 10.1016/j.molcel.2017.06.004. Epub 2017 Jun 29.

7.

BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen.

Ayoub AM, Hawk LML, Herzig RJ, Jiang J, Wisniewski AJ, Gee CT, Zhao P, Zhu JY, Berndt N, Offei-Addo NK, Scott TG, Qi J, Bradner JE, Ward TR, Schönbrunn E, Georg GI, Pomerantz WCK.

J Med Chem. 2017 Jun 22;60(12):4805-4817. doi: 10.1021/acs.jmedchem.6b01336. Epub 2017 Jun 7. Erratum in: J Med Chem. 2017 Jul 27;60(14):6458.

8.

Transcription control by the ENL YEATS domain in acute leukaemia.

Erb MA, Scott TG, Li BE, Xie H, Paulk J, Seo HS, Souza A, Roberts JM, Dastjerdi S, Buckley DL, Sanjana NE, Shalem O, Nabet B, Zeid R, Offei-Addo NK, Dhe-Paganon S, Zhang F, Orkin SH, Winter GE, Bradner JE.

Nature. 2017 Mar 9;543(7644):270-274. doi: 10.1038/nature21688. Epub 2017 Mar 1.

9.

Design and characterization of bivalent BET inhibitors.

Tanaka M, Roberts JM, Seo HS, Souza A, Paulk J, Scott TG, DeAngelo SL, Dhe-Paganon S, Bradner JE.

Nat Chem Biol. 2016 Dec;12(12):1089-1096. doi: 10.1038/nchembio.2209. Epub 2016 Oct 24.

10.

Advances in bionanomaterials for bone tissue engineering.

Scott TG, Blackburn G, Ashley M, Bayer IS, Ghosh A, Biris AS, Biswas A.

J Nanosci Nanotechnol. 2013 Jan;13(1):1-22. Review.

PMID:
23646693
11.

Acute hepatitis B in Edinburgh 1975-92: a retrospective study in a population where human immunodeficiency virus is highly prevalent.

Bath GE, Scott TG, Sibbald CJ, Upton PA, Ramsay CN, Willocks LJ.

Epidemiol Infect. 1997 Aug;119(1):85-9.

12.
13.

Haemagglutination and tissue culture adhesion of Gardnerella vaginalis.

Scott TG, Smyth CJ.

J Gen Microbiol. 1987 Aug;133(8):1999-2005.

PMID:
3502136
16.

Hepatitis-A antigen in Edinburgh.

Hopkins R, Scott TG.

Lancet. 1976 Jul 24;2(7978):206. No abstract available.

PMID:
73833
17.

Inclusions in the sural nerve in metachromatic leukodystrophy.

Duckett S, Cracco J, Graziani L, Scott TG, Solomon D, Kradin R.

Acta Neurol Latinoam. 1975;21(1-4):184-93.

PMID:
1244002
18.

Synthetic spectroscopic models related to coenzymes and base pairs. Quaternized bisnicotinamides.

Craig JH, Huang PC, Scott TG, Leonard NJ.

J Am Chem Soc. 1972 Aug 9;94(16):5872-9. No abstract available.

PMID:
4262318
19.

Water-borne typhoid fever caused by an unusual Vi-phage type in Edinburgh.

Conn NK, Heymann CS, Jamieson A, McWilliam JM, Scott TG.

J Hyg (Lond). 1972 Jun;70(2):245-53.

20.

The quantitative assay of 5'-nucleotidase in brain by histophotometry.

Scott TG.

Histochem J. 1969 Feb;1(3):215-29. No abstract available.

PMID:
5407470
21.
22.

Electrophoretic heterogeneity of bovine seminal-plasma 5'-nucleotidase.

Pilcher CW, Scott TG.

Biochem J. 1967 Sep;104(3):41C-42C. No abstract available.

23.

The specificity of 5'-nucleotidase in the brain of the mouse.

Scott TG.

J Histochem Cytochem. 1965 Nov-Dec;13(8):657-67. No abstract available.

PMID:
5866598
24.
25.

A UNIQUE PATTERN OF LOCALIZATION WITHIN THE CEREBELLUM.

SCOTT TG.

Nature. 1963 Nov 23;200:793. No abstract available.

PMID:
14087025
26.

Sensory deprivation and augmentation in the examination of enzyme adaptation.

SCOTT TG.

Nature. 1963 Feb 2;197:498-9. No abstract available.

PMID:
13992586
27.
28.

Intracellular canals in human sweat glands.

SCOTT TG.

Nature. 1960 Oct 8;188:158-9. No abstract available.

PMID:
13749405
29.

Antithromboplastin in human serum and plasma.

SCOTT TG, SYMONS C, MARKHAM RL.

Nature. 1960 Apr 16;186:248-9. No abstract available.

PMID:
14444279
30.

Fatal diphtheria in the fully immunized child.

DUNNET WN, SCHALLIBAUM EM, SCOTT TG.

Br Med J. 1960 Jan 23;1(5168):251-2. No abstract available.

31.

The bacteriology of urinary infections in paraplegia.

SCOTT TG.

J Clin Pathol. 1960 Jan;13:54-7.

32.

High glutamine levels in xanthochromic cerebrospinal fluid.

SCOTT TG.

Clin Chim Acta. 1958 Jul;3(4):343-8. No abstract available.

PMID:
13561502
33.

Intrathecal phenol for intractable pain: safety and dangers of the method.

NATHAN PW, SCOTT TG.

Lancet. 1958 Jan 11;1(7011):76-80. No abstract available.

PMID:
13503214

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