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Structural attributes influencing unbound tissue distribution.

Orozco CC, Atkinson K, Ryu S, Chang G, Keefer C, Lin J, Riccardi K, Mongillo RK, Tess D, Filipski KJ, Kalgutkar AS, Litchfield J, Scott D, Di L.

Eur J Med Chem. 2019 Oct 28:111813. doi: 10.1016/j.ejmech.2019.111813. [Epub ahead of print]


Floodplain inundation spectrum across the United States.

Scott DT, Gomez-Velez JD, Jones CN, Harvey JW.

Nat Commun. 2019 Nov 15;10(1):5194. doi: 10.1038/s41467-019-13184-4.


Mutational Landscape of Grey Zone Lymphoma.

Sarkozy C, Hung S, Takata K, Chavez E, Aoki T, Duns G, Slack GW, Telenius A, Miyata-Takata T, Viganò E, Molina TJ, Damotte D, Ben-Neriah S, Copie-Bergman C, Laurent C, Mottok A, Salles G, Savage KJ, Scott DW, Traverse-Glehen A, Steidl C.

Blood. 2019 Nov 13;134(Supplement_1):21. doi: 10.1182/blood-2019-127375.


A Survey of Genome Editing Activity for 16 Cas12a Orthologs.

Zetsche B, Strecker J, Abudayyeh OO, Gootenberg JS, Scott DA, Zhang F.

Keio J Med. 2019 Nov 14. doi: 10.2302/kjm.2019-0009-OA. [Epub ahead of print]


Associations between physical activity and bone structure in older adults: does the use of self-reported versus objective assessments of physical activity influence the relationship?

Ng CA, McMillan LB, Beck B, Humbert L, Ebeling PR, Scott D.

Osteoporos Int. 2019 Nov 13. doi: 10.1007/s00198-019-05208-y. [Epub ahead of print]


Aggression and violence at ambulance attendances where alcohol, illicit and/or pharmaceutical drugs were recorded: A 5-year study of ambulance records in Victoria, Australia.

Coomber K, Curtis A, Vandenberg B, Miller PG, Heilbronn C, Matthews S, Smith K, Wilson J, Moayeri F, Mayshak R, Lubman DI, Scott D.

Drug Alcohol Depend. 2019 Oct 28;205:107685. doi: 10.1016/j.drugalcdep.2019.107685. [Epub ahead of print]


The natural flavonoid Naringenin elicits analgesia through inhibition of NaV1.8 voltage-gated sodium channels.

Zhou Y, Cai S, Moutal A, Yu J, Gomez K, Madura CL, Shan Z, Ngan Pham NY, Serafini MJ, Dorame A, Scott DD, Francois-Moutal L, Perez-Miller S, Patek M, Khanna M, Khanna R.

ACS Chem Neurosci. 2019 Nov 7. doi: 10.1021/acschemneuro.9b00547. [Epub ahead of print]


Multi-Material Dual Gradient 3D Printing for Osteogenic Differentiation and Spatial Segregation.

Smith BT, Bittner SM, Watson E, Smoak MM, Diaz-Gomez LA, Molina ER, Kim YS, Hudgins CD, Melchiorri AJ, Scott DW, Grande-Allen KJ, Yoo JJ, Atala A, Fisher JP, Mikos AG.

Tissue Eng Part A. 2019 Nov 7. doi: 10.1089/ten.TEA.2019.0204. [Epub ahead of print]


Novel Missense Variants in ADAT3 as a Cause of Syndromic Intellectual Disability.

Thomas E, Lewis AM, Yang Y, Chanprasert S, Potocki L, Scott DA.

J Pediatr Genet. 2019 Dec;8(4):244-251. doi: 10.1055/s-0039-1693151. Epub 2019 Jul 9.


Sarcopenia in Older Adults.

Scott D.

J Clin Med. 2019 Nov 2;8(11). pii: E1844. doi: 10.3390/jcm8111844.


Marijuana-Derived Cannabinoids Trigger a CB2/PI3K Axis of Suppression of the Innate Response to Oral Pathogens.

Gu Z, Singh S, Niyogi RG, Lamont GJ, Wang H, Lamont RJ, Scott DA.

Front Immunol. 2019 Oct 15;10:2288. doi: 10.3389/fimmu.2019.02288. eCollection 2019.


ERRATUM: Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans.

Wetherill L, Lai D, Johnson EC, Anokhin A, Bauer L, Bucholz KK, Dick DM, Hariri AR, Hesselbrock V, Kamarajan C, Kramer J, Kuperman S, Meyers JL, Nurnberger JI Jr, Schuckit M, Scott DM, Taylor RE, Tischfield J, Porjesz B, Goate AM, Edenberg HJ, Foroud T, Bogdan R, Agrawal A.

Genes Brain Behav. 2019 Nov;18(8):e12608. doi: 10.1111/gbb.12608. No abstract available.


Experimental determination of second virial coefficients by small-angle X-ray scattering: a problem revisited.

Mrozowich T, Winzor DJ, Scott DJ, Patel TR.

Eur Biophys J. 2019 Dec;48(8):781-787. doi: 10.1007/s00249-019-01404-0. Epub 2019 Oct 31.


Proinflammatory Diet Increases Circulating Inflammatory Biomarkers and Falls Risk in Community-Dwelling Older Men.

Cervo MMC, Scott D, Seibel MJ, Cumming RG, Naganathan V, Blyth FM, Le Couteur DG, Handelsman DJ, Ribeiro RV, Waite LM, Shivappa N, Hebert JR, Hirani V.

J Nutr. 2019 Oct 26. pii: nxz256. doi: 10.1093/jn/nxz256. [Epub ahead of print]


A systematic review of guidelines for managing rheumatoid arthritis.

Mian A, Ibrahim F, Scott DL.

BMC Rheumatol. 2019 Oct 22;3:42. doi: 10.1186/s41927-019-0090-7. eCollection 2019.


Effects of core temperature, skin temperature, and inter-beat interval on resting metabolic rate measurements in thermoneutral conditions.

Davis GR, Bellar D, Scott D, Lavergne M.

J Therm Biol. 2019 Oct;85:102399. doi: 10.1016/j.jtherbio.2019.102399. Epub 2019 Aug 17.


Disruption of PHF21A causes syndromic intellectual disability with craniofacial anomalies, epilepsy, hypotonia, and neurobehavioral problems including autism.

Kim HG, Rosenfeld JA, Scott DA, Bénédicte G, Labonne JD, Brown J, McGuire M, Mahida S, Naidu S, Gutierrez J, Lesca G, des Portes V, Bruel AL, Sorlin A, Xia F, Capri Y, Muller E, McKnight D, Torti E, Rüschendorf F, Hummel O, Islam Z, Kolatkar PR, Layman LC, Ryu D, Kong IK, Madan-Khetarpal S, Kim CH.

Mol Autism. 2019 Oct 22;10:35. doi: 10.1186/s13229-019-0286-0. eCollection 2019.


A four-stage process for intervention description and guide development of a practice-based intervention: refining the Namaste Care intervention implementation specification for people with advanced dementia prior to a feasibility cluster randomised trial.

Walshe C, Kinley J, Patel S, Goodman C, Bunn F, Lynch J, Scott D, Lund AD, Stacpoole M, Preston N, Froggatt K.

BMC Geriatr. 2019 Oct 21;19(1):275. doi: 10.1186/s12877-019-1275-z.


Single Cell Phenotypic Profiling of 27 DLBCL Cases Reveals Marked Intertumoral and Intratumoral Heterogeneity.

Nissen MD, Kusakabe M, Wang X, Simkin G, Gracias D, Tyshchenko K, Hill A, Meskas J, Hung S, Chavez EA, Ennishi D, Aoki T, Sarkozy C, Connors JM, Farinha P, Slack GW, Gascoyne RD, Brinkman RR, Scott DW, Steidl C, Weng AP.

Cytometry A. 2019 Oct 22. doi: 10.1002/cyto.a.23919. [Epub ahead of print]


Single low-dose VSV-EBOV vaccination protects cynomolgus macaques from lethal Ebola challenge.

Marzi A, Reynolds P, Mercado-Hernandez R, Callison J, Feldmann F, Rosenke R, Thomas T, Scott DP, Hanley PW, Haddock E, Feldmann H.

EBioMedicine. 2019 Oct 16. pii: S2352-3964(19)30651-6. doi: 10.1016/j.ebiom.2019.09.055. [Epub ahead of print]


Morphologic and operative evolution of open ruptured abdominal aortic aneurysm repair.

Scott DJ, Steenberge SP, Bena JF, Lyden SP.

Ann Vasc Surg. 2019 Oct 16. pii: S0890-5096(19)30786-1. doi: 10.1016/j.avsg.2019.08.098. [Epub ahead of print]


Structure-Guided Enhancement of Selectivity of Chemical Probe Inhibitors Targeting Bacterial Seryl-tRNA Synthetase.

Cain R, Salimraj R, Punekar AS, Bellini D, Fishwick CWG, Czaplewski L, Scott DJ, Harris G, Dowson CG, Lloyd AJ, Roper DI.

J Med Chem. 2019 Nov 14;62(21):9703-9717. doi: 10.1021/acs.jmedchem.9b01131. Epub 2019 Nov 5.


Immunogenicity and Safety of the 13-Valent Pneumococcal Conjugate Vaccine Administered in a 3 + 1 versus 2 + 1 Dose Schedule Among Infants in China.

Zhu F, Hu Y, Li J, Ye Q, Young MM Jr, Liang JZ, Gruber WC, Giardina PC, Scott DA.

Pediatr Infect Dis J. 2019 Nov;38(11):1150-1158. doi: 10.1097/INF.0000000000002458.


Osteocalcin and its forms across the lifespan in adult men.

Smith C, Voisin S, Al Saedi A, Phu S, Brennan-Speranza T, Parker L, Eynon N, Hiam D, Yan X, Scott D, Blekkenhorst LC, Lewis JR, Seeman E, Byrnes E, Flicker L, Duque G, Yeap BB, Levinger I.

Bone. 2019 Oct 14;130:115085. doi: 10.1016/j.bone.2019.115085. [Epub ahead of print]


Trends in GHB-related harms based on ambulance attendances from 2012-2018 in Victoria, Australia.

Arunogiri S, Moayeri F, Crossin R, Killian JJ, Smith K, Scott D, Lubman DI.

Addiction. 2019 Oct 16. doi: 10.1111/add.14848. [Epub ahead of print]


Are you better off than you were 4 years ago? Measuring the impact of the ABS flexible endoscopy curriculum.

Weis JJ, Grubbs J, Scott DJ, Abdelfattah KR, Abdelnaby AA, Farr D, Hennessy SA.

Surg Endosc. 2019 Oct 15. doi: 10.1007/s00464-019-07176-0. [Epub ahead of print]


Decision Making About Genetic Testing Among Women With a Personal and Family History of Breast Cancer.

Scott D, Friedman S, Telli ML, Kurian AW.

J Oncol Pract. 2019 Oct 15:JOP1900221. doi: 10.1200/JOP.19.00221. [Epub ahead of print]


Letter in response to: Cooper et al. Established search filters may miss studies when identifying randomized controlled trials [J Clin Epidemiol. 2019 Apr 13;112:12-19. doi: 10.1016/j.jclinepi.2019.04.002].

Thompson JC, Scott DA.

J Clin Epidemiol. 2019 Oct 9. pii: S0895-4356(19)30624-9. doi: 10.1016/j.jclinepi.2019.09.007. [Epub ahead of print] No abstract available.


Clinical spectrum of individuals with pathogenic NF1 missense variants affecting p.Met1149, p.Arg1276, and p.Lys1423: genotype-phenotype study in neurofibromatosis type 1.

Koczkowska M, Callens T, Chen Y, Gomes A, Hicks AD, Sharp A, Johns E, Uhas KA, Armstrong L, Bosanko KA, Babovic-Vuksanovic D, Baker L, Basel DG, Bengala M, Bennett JT, Chambers C, Clarkson LK, Clementi M, Cortés FM, Cunningham M, D'Agostino MD, Delatycki MB, Digilio MC, Dosa L, Esposito S, Fox S, Freckmann ML, Fauth C, Giugliano T, Giustini S, Goetsch A, Goldberg Y, Greenwood RS, Griffis C, Gripp KW, Gupta P, Haan E, Hachen RK, Haygarth TL, Hernández-Chico C, Hodge K, Hopkin RJ, Hudgins L, Janssens S, Keller K, Kelly-Mancuso G, Kochhar A, Korf BR, Lewis AM, Liebelt J, Lichty A, Listernick RH, Lyons MJ, Maystadt I, Martinez Ojeda M, McDougall C, McGregor LK, Melis D, Mendelsohn N, Nowaczyk MJM, Ortenberg J, Panzer K, Pappas JG, Pierpont ME, Piluso G, Pinna V, Pivnick EK, Pond DA, Powell CM, Rogers C, Ruhrman Shahar N, Rutledge SL, Saletti V, Sandaradura SA, Santoro C, Schatz UA, Schreiber A, Scott DA, Sellars EA, Sheffer R, Siqveland E, Slopis JM, Smith R, Spalice A, Stockton DW, Streff H, Theos A, Tomlinson GE, Tran G, Trapane PL, Trevisson E, Ullrich NJ, Van den Ende J, Schrier Vergano SA, Wallace SE, Wangler MF, Weaver DD, Yohay KH, Zackai E, Zonana J, Zurcher V, Claes KBM, Eoli M, Martin Y, Wimmer K, De Luca A, Legius E, Messiaen LM.

Hum Mutat. 2019 Oct 8. doi: 10.1002/humu.23929. [Epub ahead of print]


Meta-analysis of fenestrated endovascular aneurysm repair versus open surgical repair of juxtarenal abdominal aortic aneurysms over the last 10 years.

Jones AD, Waduud MA, Walker P, Stocken D, Bailey MA, Scott DJA.

BJS Open. 2019 May 17;3(5):572-584. doi: 10.1002/bjs5.50178. eCollection 2019 Oct. Review.


Corrigendum to 'State of the clinical science of perioperative brain health: report from the American Society of Anesthesiologists Brain Health Initiative Summit 2018' (Br J Anaesth 2019; 123: 464-478).

Mahanna-Gabrielli E, Schenning KJ, Eriksson LI, Browndyke JN, Wright CB, Culley DJ, Evered L, Scott DA, Wang NY, Brown CH 4th, Oh E, Purdon P, Inouye S, Berger M, Whittington RA, Price CC, Deiner S.

Br J Anaesth. 2019 Dec;123(6):917. doi: 10.1016/j.bja.2019.09.014. Epub 2019 Oct 4. No abstract available.


Soil heterogeneity increases plant diversity after 20 years of manipulation during grassland restoration.

Baer SG, Adams T, Scott DA, Blair JM, Collins SL.

Ecol Appl. 2019 Oct 6:e02014. doi: 10.1002/eap.2014. [Epub ahead of print]


Microbiological and biochemical findings in relation to clinical periodontal status in active smokers, non-smokers and passive smokers.

Kanmaz B, Lamont G, Danacı G, Gogeneni H, Buduneli N, Scott DA.

Tob Induc Dis. 2019 Mar 21;17:20. doi: 10.18332/tid/104492. eCollection 2019.


Disruptive variants of CSDE1 associate with autism and interfere with neuronal development and synaptic transmission.

Guo H, Li Y, Shen L, Wang T, Jia X, Liu L, Xu T, Ou M, Hoekzema K, Wu H, Gillentine MA, Liu C, Ni H, Peng P, Zhao R, Zhang Y, Phornphutkul C, Stegmann APA, Prada CE, Hopkin RJ, Shieh JT, McWalter K, Monaghan KG, van Hasselt PM, van Gassen K, Bai T, Long M, Han L, Quan Y, Chen M, Zhang Y, Li K, Zhang Q, Tan J, Zhu T, Liu Y, Pang N, Peng J, Scott DA, Lalani SR, Azamian M, Mancini GMS, Adams DJ, Kvarnung M, Lindstrand A, Nordgren A, Pevsner J, Osei-Owusu IA, Romano C, Calabrese G, Galesi O, Gecz J, Haan E, Ranells J, Racobaldo M, Nordenskjold M, Madan-Khetarpal S, Sebastian J, Ball S, Zou X, Zhao J, Hu Z, Xia F, Liu P, Rosenfeld JA, de Vries BBA, Bernier RA, Xu ZD, Li H, Xie W, Hufnagel RB, Eichler EE, Xia K.

Sci Adv. 2019 Sep 25;5(9):eaax2166. doi: 10.1126/sciadv.aax2166. eCollection 2019 Sep.


Widening of the genetic and clinical spectrum of Lamb-Shaffer syndrome, a neurodevelopmental disorder due to SOX5 haploinsufficiency.

Zawerton A, Mignot C, Sigafoos A, Blackburn PR, Haseeb A, McWalter K, Ichikawa S, Nava C, Keren B, Charles P, Marey I, Tabet AC, Levy J, Perrin L, Hartmann A, Lesca G, Schluth-Bolard C, Monin P, Dupuis-Girod S, Guillen Sacoto MJ, Schnur RE, Zhu Z, Poisson A, El Chehadeh S, Alembik Y, Bruel AL, Lehalle D, Nambot S, Moutton S, Odent S, Jaillard S, Dubourg C, Hilhorst-Hofstee Y, Barbaro-Dieber T, Ortega L, Bhoj EJ, Masser-Frye D, Bird LM, Lindstrom K, Ramsey KM, Narayanan V, Fassi E, Willing M, Cole T, Salter CG, Akilapa R, Vandersteen A, Canham N, Rump P, Gerkes EH, Klein Wassink-Ruiter JS, Bijlsma E, Hoffer MJV, Vargas M, Wojcik A, Cherik F, Francannet C, Rosenfeld JA, Machol K, Scott DA, Bacino CA, Wang X, Clark GD, Bertoli M, Zwolinski S, Thomas RH, Akay E, Chang RC, Bressi R, Sanchez Russo R, Srour M, Russell L, Goyette AE, Dupuis L, Mendoza-Londono R, Karimov C, Joseph M, Nizon M, Cogné B, Kuechler A, Piton A; Deciphering Developmental Disorder Study, Klee EW, Lefebvre V, Clark KJ, Depienne C.

Genet Med. 2019 Oct 3. doi: 10.1038/s41436-019-0657-0. [Epub ahead of print]


Validating a diagnostic GCA ultrasonography service against temporal artery biopsy and long-term clinical outcomes.

Mukhtyar C, Myers H, Scott DGI, Misra A, Jones C.

Clin Rheumatol. 2019 Oct 1. doi: 10.1007/s10067-019-04772-2. [Epub ahead of print]


Perspective: Clinical relevance of the dichotomous classification of Alzheimer's disease biomarkers: Should there be a "gray zone"?

McRae-McKee K, Udeh-Momoh CT, Price G, Bajaj S, de Jager CA, Scott D, Hadjichrysanthou C, McNaughton E, Bracoud L, Ahmadi-Abhari S, de Wolf F, Anderson RM, Middleton LT; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement. 2019 Oct;15(10):1348-1356. doi: 10.1016/j.jalz.2019.07.010. Epub 2019 Sep 26.


Osmotic stimulation of vasopressin acutely impairs glucose regulation: a counterbalanced, crossover trial.

Jansen LT, Suh H, Adams JD, Sprong CA, Seal AD, Scott DM, Butts CL, Melander O, Kirkland TW, Vanhaecke T, Dolci A, Lemetais G, Perrier ET, Kavouras SA.

Am J Clin Nutr. 2019 Sep 27. pii: nqz236. doi: 10.1093/ajcn/nqz236. [Epub ahead of print]


Reconstructing the workforce within public health protective systems: Improving resilience, retention, service responsiveness and outcomes.

Lonne B, Higgins D, Herrenkohl TI, Scott D.

Child Abuse Negl. 2019 Sep 19:104191. doi: 10.1016/j.chiabu.2019.104191. [Epub ahead of print]


Mechanically tunable coaxial electrospun models of YAP/TAZ mechanoresponse and IGF-1R activation in osteosarcoma.

Molina ER, Chim LK, Salazar MC, Mehta SM, Menegaz BA, Lamhamedi-Cherradi SE, Satish T, Mohiuddin S, McCall D, Zaske AM, Cuglievan B, Lazar AJ, Scott DW, Grande-Allen JK, Ludwig JA, Mikos AG.

Acta Biomater. 2019 Sep 19. pii: S1742-7061(19)30641-5. doi: 10.1016/j.actbio.2019.09.029. [Epub ahead of print]


Bony stress in the lumbar spine is associated with intervertebral disc degeneration and low back pain: a retrospective case-control MRI study of patients under 25 years of age.

Chepurin D, Chamoli U, Sheldrick K, Lapkin S, Scott D, Kuan J, Diwan AD.

Eur Spine J. 2019 Nov;28(11):2470-2477. doi: 10.1007/s00586-019-06148-1. Epub 2019 Sep 16.


The double-hit signature identifies double-hit diffuse large B-cell lymphoma with genetic events cryptic to FISH.

Hilton LK, Tang J, Ben-Neriah S, Alcaide M, Jiang A, Grande BM, Rushton CK, Boyle M, Meissner B, Scott DW, Morin RD.

Blood. 2019 Oct 31;134(18):1528-1532. doi: 10.1182/blood.2019002600.


Development of a data-driven weather index for beach parks tourism.

Matthews L, Scott D, Andrey J.

Int J Biometeorol. 2019 Sep 14. doi: 10.1007/s00484-019-01799-7. [Epub ahead of print]


Secular changes in functional disability, pain, fatigue and mental well-being in early rheumatoid arthritis. A longitudinal meta-analysis.

Carpenter L, Barnett R, Mahendran P, Nikiphorou E, Gwinnutt J, Verstappen S, Scott DL, Norton S.

Semin Arthritis Rheum. 2019 Aug 24. pii: S0049-0172(19)30097-6. doi: 10.1016/j.semarthrit.2019.08.006. [Epub ahead of print] Review.


Loss of CLTRN function produces a neuropsychiatric disorder and a biochemical phenotype that mimics Hartnup disease.

Pillai NR, Yubero D, Shayota BJ, Oyarzábal A, Ghosh R, Sun Q, Azamian MS, Arjona C, Brandi N, Palau F, Lalani SR, Artuch R, García-Cazorla A, Scott DA.

Am J Med Genet A. 2019 Dec;179(12):2459-2468. doi: 10.1002/ajmg.a.61357. Epub 2019 Sep 13.


Now that They're Out: Experiences of College Athletics Teams with Openly LGBTQ Players.

Pariera K, Brody E, Scott DT.

J Homosex. 2019 Sep 11:1-19. doi: 10.1080/00918369.2019.1661727. [Epub ahead of print]


Prognostic Significance of MYC Rearrangement and Translocation Partner in Diffuse Large B-Cell Lymphoma: A Study by the Lunenburg Lymphoma Biomarker Consortium.

Rosenwald A, Bens S, Advani R, Barrans S, Copie-Bergman C, Elsensohn MH, Natkunam Y, Calaminici M, Sander B, Baia M, Smith A, Painter D, Pham L, Zhao S, Ziepert M, Jordanova ES, Molina TJ, Kersten MJ, Kimby E, Klapper W, Raemaekers J, Schmitz N, Jardin F, Stevens WBC, Hoster E, Hagenbeek A, Gribben JG, Siebert R, Gascoyne RD, Scott DW, Gaulard P, Salles G, Burton C, de Jong D, Sehn LH, Maucort-Boulch D.

J Clin Oncol. 2019 Sep 9:JCO1900743. doi: 10.1200/JCO.19.00743. [Epub ahead of print]


Phase 1 trial of a 20-valent pneumococcal conjugate vaccine in healthy adults.

Thompson A, Lamberth E, Severs J, Scully I, Tarabar S, Ginis J, Jansen KU, Gruber WC, Scott DA, Watson W.

Vaccine. 2019 Sep 30;37(42):6201-6207. doi: 10.1016/j.vaccine.2019.08.048. Epub 2019 Sep 5.


Acute toxicity of copper to the larval stage of three species of ambystomatid salamanders.

Weir SM, Yu S, Scott DE, Lance SL.

Ecotoxicology. 2019 Nov;28(9):1023-1031. doi: 10.1007/s10646-019-02102-5. Epub 2019 Sep 5.


Multidisciplinary Simulation Activity Effectively Prepares Residents for Participation in Patient Safety Activities.

Weis JJ, Croft CL, Bhoja R, Lee JH, Scott DJ.

J Surg Educ. 2019 Sep 2. pii: S1931-7204(19)30269-7. doi: 10.1016/j.jsurg.2019.07.015. [Epub ahead of print]


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