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Items: 1 to 50 of 5291

1.

Defining and Targeting Adaptations to Oncogenic KRASG12C Inhibition Using Quantitative Temporal Proteomics.

Santana-Codina N, Chandhoke AS, Yu Q, Małachowska B, Kuljanin M, Gikandi A, Stańczak M, Gableske S, Jedrychowski MP, Scott DA, Aguirre AJ, Fendler W, Gray NS, Mancias JD.

Cell Rep. 2020 Mar 31;30(13):4584-4599.e4. doi: 10.1016/j.celrep.2020.03.021.

2.

The role of cardiopulmonary exercise testing and echocardiography prior to elective endovascular aneurysm repair.

Straw S, Waduud MA, Drozd M, Warman P, Bailey MA, Hammond CJ, Abdel-Rahman S, Witte KK, Scott D.

Ann R Coll Surg Engl. 2020 Apr 1:1-8. doi: 10.1308/rcsann.2020.0045. [Epub ahead of print]

PMID:
32233869
3.

The value, impact and role of nurses in rheumatology outpatient care: Critical review of the literature.

Lempp H, Baggott R, Scott DL, Parker L, Bosworth A, Georgopoulou S, Firth J.

Musculoskeletal Care. 2020 Mar 28. doi: 10.1002/msc.1467. [Epub ahead of print] Review.

PMID:
32222059
4.

Bortezomib consolidation or maintenance following immunochemotherapy and autologous stem cell transplantation for mantle cell lymphoma: CALGB/Alliance 50403.

Kaplan LD, Maurer MJ, Stock W, Bartlett NL, Fulton N, Pettinger A, Byrd JC, Blum KA, LaCasce AS, Hsi ED, Liu YT, Scott DW, Hurd D, Ruppert AS, Hernandez-Ilizaliturri F, Leonard JP, Cheson BD.

Am J Hematol. 2020 Mar 13. doi: 10.1002/ajh.25783. [Epub ahead of print]

PMID:
32170769
5.

Does the child's health influence the caregiver's health using the EQ-5D instruments?

Verstraete J, Scott D.

S Afr J Physiother. 2020 Feb 26;76(1):1343. doi: 10.4102/sajp.v76i1.1343. eCollection 2020.

6.

Coding and non-coding drivers of mantle cell lymphoma identified through exome and genome sequencing.

Pararajalingam P, Coyle KM, Arthur S, Thomas N, Alcaide M, Meissner B, Boyle M, Qureshi Q, Grande BM, Rushton C, Slack GW, Mungall A, Tam C, Agarwal R, Dawson SJ, Lenz G, Balasubramanian S, Gascoyne RD, Steidl C, Connors J, Villa D, Audas TE, Marra MA, Johnson NA, Scott DW, Morin RD.

Blood. 2020 Mar 5. pii: blood.2019002385. doi: 10.1182/blood.2019002385. [Epub ahead of print]

PMID:
32160292
7.

Regulation of Cullin-RING E3 ligase dynamics by Inositol hexakisphosphate.

Scott DC, Kleiger G.

Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6292-6294. doi: 10.1073/pnas.2001683117. Epub 2020 Mar 10. No abstract available.

PMID:
32156730
8.

An open-source drug discovery platform enables ultra-large virtual screens.

Gorgulla C, Boeszoermenyi A, Wang ZF, Fischer PD, Coote P, Padmanabha Das KM, Malets YS, Radchenko DS, Moroz YS, Scott DA, Fackeldey K, Hoffmann M, Iavniuk I, Wagner G, Arthanari H.

Nature. 2020 Mar 9. doi: 10.1038/s41586-020-2117-z. [Epub ahead of print]

PMID:
32152607
9.

HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes.

Xiao T, Frey G, Fu Q, Lavine CL, Scott DA, Seaman MS, Chou JJ, Chen B.

Nat Chem Biol. 2020 Mar 9. doi: 10.1038/s41589-020-0496-y. [Epub ahead of print]

PMID:
32152540
10.

Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition.

Khan A, Valli E, Lam H, Scott DA, Murray J, Hanssen KM, Eden G, Gamble LD, Pandher R, Flemming CL, Allan S, Osterman AL, Haber M, Norris MD, Fletcher JI, Yu DMT.

Oncogene. 2020 Mar 2. doi: 10.1038/s41388-020-1235-2. [Epub ahead of print]

PMID:
32123312
11.

The nose is an organ too.

Mukhtyar C, Mills J, Scott DGI.

Rheumatology (Oxford). 2020 Mar 2. pii: keaa073. doi: 10.1093/rheumatology/keaa073. [Epub ahead of print] No abstract available.

PMID:
32118271
12.

Recombinant Factor VIII Fc Inhibits B Cell Activation via Engagement of the FcγRIIB Receptor.

Georgescu MT, Moorehead PC, Liu T, Dumont J, Scott DW, Hough C, Lillicrap D.

Front Immunol. 2020 Feb 7;11:138. doi: 10.3389/fimmu.2020.00138. eCollection 2020.

13.

Conformational rearrangements in the N-domain of Escherichia coli FepA during ferric enterobactin transport.

Majumdar A, Trinh V, Moore KJ, Smallwood CR, Kumar A, Yang T, Scott DC, Long NJ, Newton SM, Klebba PE.

J Biol Chem. 2020 Feb 25. pii: jbc.RA119.011850. doi: 10.1074/jbc.RA119.011850. [Epub ahead of print]

14.

TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma.

Ennishi D, Healy S, Bashashati A, Saberi S, Hother C, Mottok A, Chan FC, Chong L, Abraham L, Kridel R, Boyle M, Meissner B, Aoki T, Takata K, Woolcock BW, Viganò E, Gold M, Molday LL, Molday RS, Telenius A, Li MY, Wretham N, Dos Santos N, Wong M, Viller NN, Uger RA, Duns G, Baticados A, Madero A, Bristow BN, Farinha P, Slack GW, Ben-Neriah S, Lai D, Zhang AW, Salehi S, Shulha HP, Chiu DS, Mostafavi S, Gerrie AS, Huang DW, Rushton C, Villa D, Sehn LH, Savage KJ, Mungall AJ, Weng AP, Bally MB, Morin RD, Cohen Freue GV, Staudt LM, Connors JM, Marra MA, Shah SP, Gascoyne RD, Scott DW, Steidl C.

Nat Med. 2020 Feb 24. doi: 10.1038/s41591-020-0757-z. [Epub ahead of print]

PMID:
32094924
15.

Self-reported sleep disturbance in ambulance attendances for suicidal ideation and attempted suicide between 2012 and 2017.

Ogeil RP, Witt K, Scott D, Smith K, Lubman DI.

J Affect Disord. 2020 Mar 15;265:364-371. doi: 10.1016/j.jad.2019.11.158. Epub 2019 Dec 2.

PMID:
32090761
16.

10th European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals.

Tourdot S, Abdolzade-Bavil A, Bessa J, Broët P, Fogdell-Hahn A, Giorgi M, Jawa V, Kuranda K, Legrand N, Pattijn S, Pedras-Vasconcelos JA, Rudy A, Salmikangas P, Scott DW, Snoeck V, Smith N, Spindeldreher S, Kramer D.

MAbs. 2020 Jan-Dec;12(1):1725369. doi: 10.1080/19420862.2020.1725369.

17.

Co-design of an oral health promotion animated film with families in the South of England.

Scott DAH, Currie C, Stones T, Scott C, John J, Wanyonyi K.

Br Dent J. 2020 Feb;228(3):164-170. doi: 10.1038/s41415-020-1208-4.

PMID:
32060458
18.

Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.

de Wit E, Feldmann F, Cronin J, Jordan R, Okumura A, Thomas T, Scott D, Cihlar T, Feldmann H.

Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6771-6776. doi: 10.1073/pnas.1922083117. Epub 2020 Feb 13.

19.

A Phosphinine-derived 1-Phospha-7-bora-norbornadiene: Frustrated Lewis Pair Type Activation of Triple Bonds.

Leitl J, Jupp AR, Habraken ERM, Streitferdt V, Coburger P, Scott DJ, Gschwind RM, Müller C, Slootweg JC, Wolf R.

Chemistry. 2020 Feb 13. doi: 10.1002/chem.202000266. [Epub ahead of print]

PMID:
32052879
20.

Simple photoreduction of carbon dioxide to formic acid and true quantum yield.

Omadoko O, Scott D, Hickman R, Myers DL.

Phys Chem Chem Phys. 2020 Feb 26;22(8):4632-4639. doi: 10.1039/c9cp06707h.

PMID:
32052000
21.

GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration.

Ackeifi C, Wang P, Karakose E, Manning Fox JE, González BJ, Liu H, Wilson J, Swartz E, Berrouet C, Li Y, Kumar K, MacDonald PE, Sanchez R, Thorens B, DeVita R, Homann D, Egli D, Scott DK, Garcia-Ocaña A, Stewart AF.

Sci Transl Med. 2020 Feb 12;12(530). pii: eaaw9996. doi: 10.1126/scitranslmed.aaw9996.

PMID:
32051230
22.

Anticipatory care planning intervention for older adults at risk of functional decline: study protocol for a primary care cluster feasibility randomised trial.

Brazil K, Scott D, Wallace E, Clarke M, Fahey T, Gillespie P, O'Halloran P, Cardwell C, Carter G, McGlade K, Doyle F.

Trials. 2020 Feb 11;21(1):168. doi: 10.1186/s13063-020-4100-2.

23.

4-1BBL Regulates the Polarization of Macrophages, and Inhibition of 4-1BBL Signaling Alleviates Imiquimod-Induced Psoriasis.

Miki H, Han KH, Scott D, Croft M, Kang YJ.

J Immunol. 2020 Apr 1;204(7):1892-1903. doi: 10.4049/jimmunol.1900983. Epub 2020 Feb 10.

PMID:
32041783
24.

Ultrasensitive Detection of NOTCH1 c.7544_7545delCT Mutations in Chronic Lymphocytic Leukemia by Droplet Digital PCR Reveals High Frequency of Subclonal Mutations and Predicts Clinical Outcome in Cases with Trisomy 12.

Hoofd C, Huang SJ, Gusscott S, Lam S, Wong R, Johnston A, Ben-Neriah S, Steidl C, Scott DW, Bruyere H, Gillan TL, Toze CL, Gerrie AS, Weng AP.

J Mol Diagn. 2020 Feb 6. pii: S1525-1578(20)30015-5. doi: 10.1016/j.jmoldx.2020.01.008. [Epub ahead of print]

PMID:
32036086
25.

Deficiency of FRAS1-related extracellular matrix 1 (FREM1) causes congenital diaphragmatic hernia in humans and mice.

Beck TF, Veenma D, Shchelochkov OA, Yu Z, Kim BJ, Zaveri HP, van Bever Y, Choi S, Douben H, Bertin TK, Patel PI, Lee B, Tibboel D, de Klein A, Stockton DW, Justice MJ, Scott DA.

Hum Mol Genet. 2020 Feb 4. pii: ddz307. doi: 10.1093/hmg/ddz307. [Epub ahead of print] No abstract available.

PMID:
32016392
26.

Factor VIII: Perspectives on Immunogenicity and Tolerogenic Strategies.

Scott DW, Pratt KP.

Front Immunol. 2020 Jan 17;10:3078. doi: 10.3389/fimmu.2019.03078. eCollection 2019. Review.

27.

The National Ambulance Surveillance System: A novel method for monitoring acute alcohol, illicit and pharmaceutical drug related-harms using coded Australian ambulance clinical records.

Lubman DI, Matthews S, Heilbronn C, Killian JJ, Ogeil RP, Lloyd B, Witt K, Crossin R, Smith K, Bosley E, Carney R, Wilson A, Eastham M, Keene T, Shipp C, Scott D.

PLoS One. 2020 Jan 31;15(1):e0228316. doi: 10.1371/journal.pone.0228316. eCollection 2020.

28.

Assessment of Practice Management Entrustable Professional Activities by Pharmacists in North Dakota.

Scott DM, Naughton CA, Petry N, Friesner DL.

Am J Pharm Educ. 2019 Dec;83(10):7486. doi: 10.5688/ajpe7486.

29.

BAZ2B haploinsufficiency as a cause of developmental delay, intellectual disability, and autism spectrum disorder.

Scott TM, Guo H, Eichler EE, Rosenfeld JA, Pang K, Liu Z, Lalani S, Bi W, Yang Y, Bacino CA, Streff H, Lewis AM, Koenig MK, Thiffault I, Bellomo A, Everman DB, Jones JR, Stevenson RE, Bernier R, Gilissen C, Pfundt R, Hiatt SM, Cooper GM, Holder JL, Scott DA.

Hum Mutat. 2020 Jan 30. doi: 10.1002/humu.23992. [Epub ahead of print]

PMID:
31999386
30.

Tolerating Factor VIII: Recent Progress.

Lacroix-Desmazes S, Voorberg J, Lillicrap D, Scott DW, Pratt KP.

Front Immunol. 2020 Jan 10;10:2991. doi: 10.3389/fimmu.2019.02991. eCollection 2019. Review.

31.

Carrier-Induced Hyporesponsiveness to Pneumococcal Conjugate Vaccines: The Influence of Serotypes, Timing, and Previous Vaccine Dose Unraveled.

Dagan R, Jiang Q, Juergens C, Trammel J, Gruber WC, Scott DA.

Clin Infect Dis. 2020 Jan 29. pii: ciaa083. doi: 10.1093/cid/ciaa083. [Epub ahead of print]

PMID:
31995183
32.

Reproducibility of histologic prognostic parameters for mantle cell lymphoma: cytology, Ki67, p53 and SOX11.

Croci GA, Hoster E, Beà S, Clot G, Enjuanes A, Scott DW, Cabeçadas J, Veloza L, Campo E, Clasen-Linde E, Goswami RS, Helgeland L, Pileri S, Rymkiewicz G, Reinke S, Dreyling M, Klapper W.

Virchows Arch. 2020 Jan 23. doi: 10.1007/s00428-020-02750-7. [Epub ahead of print]

PMID:
31975037
33.

A group intervention to improve quality of life for people with advanced dementia living in care homes: the Namaste feasibility cluster RCT.

Froggatt K, Best A, Bunn F, Burnside G, Coast J, Dunleavy L, Goodman C, Hardwick B, Jackson C, Kinley J, Davidson Lund A, Lynch J, Mitchell P, Myring G, Patel S, Algorta GP, Preston N, Scott D, Silvera K, Walshe C.

Health Technol Assess. 2020 Jan;24(6):1-140. doi: 10.3310/hta24060.

34.

Multiple mitochondrial dysfunctions syndrome 1: An unusual cause of developmental pulmonary hypertension.

Birjiniuk A, Glinton KE, Villafranco N, Boyer S, Laufman J, Mizerik E, Scott D, Elsea SH, Galambos C, Varghese NP, Scaglia F.

Am J Med Genet A. 2020 Apr;182(4):755-761. doi: 10.1002/ajmg.a.61491. Epub 2020 Jan 22.

PMID:
31970900
35.

Objective quantification of BCL2 protein by multiplex immunofluorescence in routine biopsy samples of diffuse large B-cell lymphoma demonstrates associations with survival and BCL2 gene alterations.

Chen L, Tyryshkin K, Moore A, Scott DW, Steidl C, Li Y, Shepherd LE, Rauh M, Deng L, Good D, Virk S, Chen BE, Crocker S, Baetz T, LeBrun DP.

Leuk Lymphoma. 2020 Jan 16:1-11. doi: 10.1080/10428194.2020.1713318. [Epub ahead of print]

PMID:
31942813
36.

Genetic Engineering of T Cells for Immune Tolerance.

Scott DW.

Mol Ther Methods Clin Dev. 2019 Dec 24;16:103-107. doi: 10.1016/j.omtm.2019.11.022. eCollection 2020 Mar 13. Review.

37.

Benzopyrimidodiazepinone inhibitors of TNK2.

Groendyke BJ, Powell CE, Feru F, Gero TW, Li Z, Szabo H, Pang K, Feutrill J, Chen B, Li B, Gray NS, Scott DA.

Bioorg Med Chem Lett. 2020 Feb 15;30(4):126948. doi: 10.1016/j.bmcl.2020.126948. Epub 2020 Jan 7.

PMID:
31928839
38.

Structural Insights Into TDP-43 and Effects of Post-translational Modifications.

François-Moutal L, Perez-Miller S, Scott DD, Miranda VG, Mollasalehi N, Khanna M.

Front Mol Neurosci. 2019 Dec 17;12:301. doi: 10.3389/fnmol.2019.00301. eCollection 2019. Review.

39.

Appraisal of the entrustable professional activities (EPAs) patient care provider domain by North Dakota pharmacists.

Scott DM, Kelsch MP, Hanel M, Friesner DL.

Pharm Pract (Granada). 2019 Oct-Dec;17(4):1607. doi: 10.18549/PharmPract.2019.4.1607. Epub 2019 Dec 1.

40.

Exploring Targeted Degradation Strategy for Oncogenic KRASG12C.

Zeng M, Xiong Y, Safaee N, Nowak RP, Donovan KA, Yuan CJ, Nabet B, Gero TW, Feru F, Li L, Gondi S, Ombelets LJ, Quan C, Jänne PA, Kostic M, Scott DA, Westover KD, Fischer ES, Gray NS.

Cell Chem Biol. 2020 Jan 16;27(1):19-31.e6. doi: 10.1016/j.chembiol.2019.12.006. Epub 2019 Dec 26.

PMID:
31883964
41.

Nutritional strategies for maintaining muscle mass and strength from middle age to later life: A narrative review.

Cruz-Jentoft AJ, Dawson Hughes B, Scott D, Sanders KM, Rizzoli R.

Maturitas. 2020 Feb;132:57-64. doi: 10.1016/j.maturitas.2019.11.007. Epub 2019 Nov 27. Review.

PMID:
31883664
42.

Further delineation of the phenotypic spectrum associated with hemizygous loss-of-function variants in NONO.

Sewani M, Nugent K, Blackburn PR, Tarnowski JM, Hernandez-Garcia A, Amiel J, Whalen S, Keren B, Courtin T, Rosenfeld JA, Yang Y, Patterson MC, Pichurin P, McLean SD, Scott DA.

Am J Med Genet A. 2020 Apr;182(4):652-658. doi: 10.1002/ajmg.a.61466. Epub 2019 Dec 28.

PMID:
31883306
43.

HB-EGF Signaling Is Required for Glucose-Induced Pancreatic β-Cell Proliferation in Rats.

Maachi H, Fergusson G, Ethier M, Brill GN, Katz LS, Honig LB, Metukuri MR, Scott DK, Ghislain J, Poitout V.

Diabetes. 2020 Mar;69(3):369-380. doi: 10.2337/db19-0643. Epub 2019 Dec 27.

PMID:
31882563
44.

Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways.

Hill S, Reichermeier K, Scott DC, Samentar L, Coulombe-Huntington J, Izzi L, Tang X, Ibarra R, Bertomeu T, Moradian A, Sweredoski MJ, Caberoy N, Schulman BA, Sicheri F, Tyers M, Kleiger G.

Elife. 2019 Dec 23;8. pii: e51163. doi: 10.7554/eLife.51163.

45.

Enantioselective Synthesis of Polycyclic γ-Lactams with Multiple Chiral Carbon Centers via Ni(0)-Catalyzed Asymmetric Carbonylative Cycloadditions without Stirring.

Ashida K, Hoshimoto Y, Tohnai N, Scott DE, Ohashi M, Imaizumi H, Tsuchiya Y, Ogoshi S.

J Am Chem Soc. 2020 Jan 22;142(3):1594-1602. doi: 10.1021/jacs.9b12493. Epub 2020 Jan 8.

PMID:
31868355
46.

Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.

Makarova KS, Wolf YI, Iranzo J, Shmakov SA, Alkhnbashi OS, Brouns SJJ, Charpentier E, Cheng D, Haft DH, Horvath P, Moineau S, Mojica FJM, Scott D, Shah SA, Siksnys V, Terns MP, Venclovas Č, White MF, Yakunin AF, Yan W, Zhang F, Garrett RA, Backofen R, van der Oost J, Barrangou R, Koonin EV.

Nat Rev Microbiol. 2020 Feb;18(2):67-83. doi: 10.1038/s41579-019-0299-x. Epub 2019 Dec 19. Review.

PMID:
31857715
47.

Single-Cell Transcriptome Analysis Reveals Disease-Defining T-cell Subsets in the Tumor Microenvironment of Classic Hodgkin Lymphoma.

Aoki T, Chong LC, Takata K, Milne K, Hav M, Colombo A, Chavez EA, Nissen M, Wang X, Miyata-Takata T, Lam V, Viganò E, Woolcock BW, Telenius A, Li MY, Healy S, Ghesquiere C, Kos D, Goodyear T, Veldman J, Zhang AW, Kim J, Saberi S, Ding J, Farinha P, Weng AP, Savage KJ, Scott DW, Krystal G, Nelson BH, Mottok A, Merchant A, Shah SP, Steidl C.

Cancer Discov. 2020 Mar;10(3):406-421. doi: 10.1158/2159-8290.CD-19-0680. Epub 2019 Dec 19.

PMID:
31857391
48.

Vaccine Protection against Multidrug-Resistant Klebsiella pneumoniae in a Nonhuman Primate Model of Severe Lower Respiratory Tract Infection.

Malachowa N, Kobayashi SD, Porter AR, Freedman B, Hanley PW, Lovaglio J, Saturday GA, Gardner DJ, Scott DP, Griffin A, Cordova K, Long D, Rosenke R, Sturdevant DE, Bruno D, Martens C, Kreiswirth BN, DeLeo FR.

mBio. 2019 Dec 17;10(6). pii: e02994-19. doi: 10.1128/mBio.02994-19.

49.

Direct catalytic transformation of white phosphorus into arylphosphines and phosphonium salts.

Lennert U, Arockiam PB, Streitferdt V, Scott DJ, Rödl C, Gschwind RM, Wolf R.

Nat Catal. 2019 Dec;2(12):1101-1106. doi: 10.1038/s41929-019-0378-4. Epub 2019 Nov 18.

PMID:
31844839
50.

Improved Physical Exam Documentation in a Pediatric After-Hours Clinic.

Kinlaw S, Dailey M, Scott D, Hanchey S, Tumin D, Higginson A.

Am J Med Qual. 2019 Dec 13:1062860619893454. doi: 10.1177/1062860619893454. [Epub ahead of print] No abstract available.

PMID:
31833380

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