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Items: 1 to 50 of 180

1.

BRCA Reversion Mutations in Circulating Tumor DNA Predict Primary and Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma.

Lin KK, Harrell MI, Oza AM, Oaknin A, Ray-Coquard I, Tinker AV, Helman E, Radke MR, Say C, Vo LT, Mann E, Isaacson JD, Maloney L, O'Malley DM, Chambers SK, Kaufmann SH, Scott CL, Konecny GE, Coleman RL, Sun JX, Giordano H, Brenton JD, Harding TC, McNeish IA, Swisher EM.

Cancer Discov. 2018 Nov 13. pii: CD-18-0715. doi: 10.1158/2159-8290.CD-18-0715. [Epub ahead of print]

PMID:
30425037
2.

Tissue Unit-ed: Lung Cells Team up to Drive Alveolar Macrophage Development.

Scott CL, Guilliams M.

Cell. 2018 Nov 1;175(4):898-900. doi: 10.1016/j.cell.2018.10.031.

PMID:
30388447
3.

Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma.

Kondrashova O, Topp M, Nesic K, Lieschke E, Ho GY, Harrell MI, Zapparoli GV, Hadley A, Holian R, Boehm E, Heong V, Sanij E, Pearson RB, Krais JJ, Johnson N, McNally O, Ananda S, Alsop K, Hutt KJ, Kaufmann SH, Lin KK, Harding TC, Traficante N; Australian Ovarian Cancer Study (AOCS), deFazio A, McNeish IA, Bowtell DD, Swisher EM, Dobrovic A, Wakefield MJ, Scott CL.

Nat Commun. 2018 Sep 28;9(1):3970. doi: 10.1038/s41467-018-05564-z.

4.

Pharmacist services for non-hospitalised patients.

de Barra M, Scott CL, Scott NW, Johnston M, de Bruin M, Nkansah N, Bond CM, Matheson CI, Rackow P, Williams AJ, Watson MC.

Cochrane Database Syst Rev. 2018 Sep 4;9:CD013102. doi: 10.1002/14651858.CD013102. Review.

PMID:
30178872
5.

'NOTCHing up' the In Vitro Production of Dendritic Cells.

Guilliams M, Scott CL.

Trends Immunol. 2018 Oct;39(10):765-767. doi: 10.1016/j.it.2018.08.002. Epub 2018 Aug 24.

PMID:
30150090
6.

Which patients with a parapneumonic effusion need a chest tube?

Helgeson SA, Hiroto BT, Billings SJ, Scott CL, Lewis MD.

Cleve Clin J Med. 2018 Aug;85(8):609-611. doi: 10.3949/ccjm.85a.17036. No abstract available.

7.

The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages.

Scott CL, T'Jonck W, Martens L, Todorov H, Sichien D, Soen B, Bonnardel J, De Prijck S, Vandamme N, Cannoodt R, Saelens W, Vanneste B, Toussaint W, De Bleser P, Takahashi N, Vandenabeele P, Henri S, Pridans C, Hume DA, Lambrecht BN, De Baetselier P, Milling SWF, Van Ginderachter JA, Malissen B, Berx G, Beschin A, Saeys Y, Guilliams M.

Immunity. 2018 Aug 21;49(2):312-325.e5. doi: 10.1016/j.immuni.2018.07.004. Epub 2018 Jul 31.

8.

The role of Kupffer cells in hepatic iron and lipid metabolism.

Scott CL, Guilliams M.

J Hepatol. 2018 Nov;69(5):1197-1199. doi: 10.1016/j.jhep.2018.02.013. Epub 2018 Jul 9. No abstract available.

PMID:
30001821
9.

Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility.

Nguyen QN, Zerafa N, Liew SH, Morgan FH, Strasser A, Scott CL, Findlay JK, Hickey M, Hutt KJ.

Cell Death Dis. 2018 May 23;9(6):618. doi: 10.1038/s41419-018-0633-7.

10.

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation.

Voet S, Mc Guire C, Hagemeyer N, Martens A, Schroeder A, Wieghofer P, Daems C, Staszewski O, Vande Walle L, Jordao MJC, Sze M, Vikkula HK, Demeestere D, Van Imschoot G, Scott CL, Hoste E, Gonçalves A, Guilliams M, Lippens S, Libert C, Vandenbroucke RE, Kim KW, Jung S, Callaerts-Vegh Z, Callaerts P, de Wit J, Lamkanfi M, Prinz M, van Loo G.

Nat Commun. 2018 May 23;9(1):2036. doi: 10.1038/s41467-018-04376-5.

11.

Macrophages and lipid metabolism.

Remmerie A, Scott CL.

Cell Immunol. 2018 Aug;330:27-42. doi: 10.1016/j.cellimm.2018.01.020. Epub 2018 Feb 2.

12.

Targeting DNA repair: the genome as a potential biomarker.

Nesic K, Wakefield M, Kondrashova O, Scott CL, McNeish IA.

J Pathol. 2018 Apr;244(5):586-597. doi: 10.1002/path.5025. Epub 2018 Feb 10. Review.

PMID:
29282716
13.

Barrier-tissue macrophages: functional adaptation to environmental challenges.

Mowat AM, Scott CL, Bain CC.

Nat Med. 2017 Nov 7;23(11):1258-1270. doi: 10.1038/nm.4430. [Epub ahead of print] Review.

PMID:
29117177
14.

Non-alcoholic steatohepatitis induces transient changes within the liver macrophage pool.

Devisscher L, Scott CL, Lefere S, Raevens S, Bogaerts E, Paridaens A, Verhelst X, Geerts A, Guilliams M, Van Vlierberghe H.

Cell Immunol. 2017 Dec;322:74-83. doi: 10.1016/j.cellimm.2017.10.006. Epub 2017 Oct 16.

PMID:
29111158
15.

TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine.

Bain CC, Montgomery J, Scott CL, Kel JM, Girard-Madoux MJH, Martens L, Zangerle-Murray TFP, Ober-Blöbaum J, Lindenbergh-Kortleve D, Samsom JN, Henri S, Lawrence T, Saeys Y, Malissen B, Dalod M, Clausen BE, Mowat AM.

Nat Commun. 2017 Sep 20;8(1):620. doi: 10.1038/s41467-017-00658-6.

16.

Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial.

Coleman RL, Oza AM, Lorusso D, Aghajanian C, Oaknin A, Dean A, Colombo N, Weberpals JI, Clamp A, Scambia G, Leary A, Holloway RW, Gancedo MA, Fong PC, Goh JC, O'Malley DM, Armstrong DK, Garcia-Donas J, Swisher EM, Floquet A, Konecny GE, McNeish IA, Scott CL, Cameron T, Maloney L, Isaacson J, Goble S, Grace C, Harding TC, Raponi M, Sun J, Lin KK, Giordano H, Ledermann JA; ARIEL3 investigators.

Lancet. 2017 Oct 28;390(10106):1949-1961. doi: 10.1016/S0140-6736(17)32440-6. Epub 2017 Sep 12. Erratum in: Lancet. 2017 Oct 28;390(10106):1948.

17.

Traumatic brain injury impairs sensorimotor function in mice.

Sackheim AM, Stockwell D, Villalba N, Haines L, Scott CL, Russell S, Hammack SE, Freeman K.

J Surg Res. 2017 Jun 1;213:100-109. doi: 10.1016/j.jss.2017.02.016. Epub 2017 Feb 23.

18.

Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma.

Kondrashova O, Nguyen M, Shield-Artin K, Tinker AV, Teng NNH, Harrell MI, Kuiper MJ, Ho GY, Barker H, Jasin M, Prakash R, Kass EM, Sullivan MR, Brunette GJ, Bernstein KA, Coleman RL, Floquet A, Friedlander M, Kichenadasse G, O'Malley DM, Oza A, Sun J, Robillard L, Maloney L, Bowtell D, Giordano H, Wakefield MJ, Kaufmann SH, Simmons AD, Harding TC, Raponi M, McNeish IA, Swisher EM, Lin KK, Scott CL; AOCS Study Group.

Cancer Discov. 2017 Sep;7(9):984-998. doi: 10.1158/2159-8290.CD-17-0419. Epub 2017 Jun 6.

19.

Teaching Psychological Assessments to Forensic Psychiatry Fellows: A Practical Guide.

Scott CL, McDermott BE.

Acad Psychiatry. 2017 Dec;41(6):803-806. doi: 10.1007/s40596-017-0713-5. Epub 2017 Jun 2. No abstract available.

PMID:
28577117
20.

Does niche competition determine the origin of tissue-resident macrophages?

Guilliams M, Scott CL.

Nat Rev Immunol. 2017 Jul;17(7):451-460. doi: 10.1038/nri.2017.42. Epub 2017 May 2.

PMID:
28461703
21.

Myocardial Infarction Primes Autoreactive T Cells through Activation of Dendritic Cells.

Van der Borght K, Scott CL, Nindl V, Bouché A, Martens L, Sichien D, Van Moorleghem J, Vanheerswynghels M, De Prijck S, Saeys Y, Ludewig B, Gillebert T, Guilliams M, Carmeliet P, Lambrecht BN.

Cell Rep. 2017 Mar 21;18(12):3005-3017. doi: 10.1016/j.celrep.2017.02.079.

22.

Development of conventional dendritic cells: from common bone marrow progenitors to multiple subsets in peripheral tissues.

Sichien D, Lambrecht BN, Guilliams M, Scott CL.

Mucosal Immunol. 2017 Jul;10(4):831-844. doi: 10.1038/mi.2017.8. Epub 2017 Feb 15. Review.

PMID:
28198365
23.

Interventions to improve antibiotic prescribing practices for hospital inpatients.

Davey P, Marwick CA, Scott CL, Charani E, McNeil K, Brown E, Gould IM, Ramsay CR, Michie S.

Cochrane Database Syst Rev. 2017 Feb 9;2:CD003543. doi: 10.1002/14651858.CD003543.pub4. Review.

24.

Mainstreaming cancer genetics: A model integrating germline BRCA testing into routine ovarian cancer clinics.

Kentwell M, Dow E, Antill Y, Wrede CD, McNally O, Higgs E, Hamilton A, Ananda S, Lindeman GJ, Scott CL.

Gynecol Oncol. 2017 Apr;145(1):130-136. doi: 10.1016/j.ygyno.2017.01.030. Epub 2017 Feb 3.

PMID:
28162234
25.

Isolation and Identification of Intestinal Myeloid Cells.

Scott CL, Bain CC, Mowat AM.

Methods Mol Biol. 2017;1559:223-239. doi: 10.1007/978-1-4939-6786-5_15.

PMID:
28063047
26.

The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity.

Laoui D, Keirsse J, Morias Y, Van Overmeire E, Geeraerts X, Elkrim Y, Kiss M, Bolli E, Lahmar Q, Sichien D, Serneels J, Scott CL, Boon L, De Baetselier P, Mazzone M, Guilliams M, Van Ginderachter JA.

Nat Commun. 2016 Dec 23;7:13720. doi: 10.1038/ncomms13720.

27.

Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial.

Swisher EM, Lin KK, Oza AM, Scott CL, Giordano H, Sun J, Konecny GE, Coleman RL, Tinker AV, O'Malley DM, Kristeleit RS, Ma L, Bell-McGuinn KM, Brenton JD, Cragun JM, Oaknin A, Ray-Coquard I, Harrell MI, Mann E, Kaufmann SH, Floquet A, Leary A, Harding TC, Goble S, Maloney L, Isaacson J, Allen AR, Rolfe L, Yelensky R, Raponi M, McNeish IA.

Lancet Oncol. 2017 Jan;18(1):75-87. doi: 10.1016/S1470-2045(16)30559-9. Epub 2016 Nov 29.

28.

Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species.

Guilliams M, Dutertre CA, Scott CL, McGovern N, Sichien D, Chakarov S, Van Gassen S, Chen J, Poidinger M, De Prijck S, Tavernier SJ, Low I, Irac SE, Mattar CN, Sumatoh HR, Low GHL, Chung TJK, Chan DKH, Tan KK, Hon TLK, Fossum E, Bogen B, Choolani M, Chan JKY, Larbi A, Luche H, Henri S, Saeys Y, Newell EW, Lambrecht BN, Malissen B, Ginhoux F.

Immunity. 2016 Sep 20;45(3):669-684. doi: 10.1016/j.immuni.2016.08.015. Epub 2016 Sep 13.

29.

IRF8 Transcription Factor Controls Survival and Function of Terminally Differentiated Conventional and Plasmacytoid Dendritic Cells, Respectively.

Sichien D, Scott CL, Martens L, Vanderkerken M, Van Gassen S, Plantinga M, Joeris T, De Prijck S, Vanhoutte L, Vanheerswynghels M, Van Isterdael G, Toussaint W, Madeira FB, Vergote K, Agace WW, Clausen BE, Hammad H, Dalod M, Saeys Y, Lambrecht BN, Guilliams M.

Immunity. 2016 Sep 20;45(3):626-640. doi: 10.1016/j.immuni.2016.08.013. Epub 2016 Sep 13.

30.

Psychiatric education in the correctional setting: challenges and opportunities.

Holoyda BJ, Scott CL.

Int Rev Psychiatry. 2017 Feb;29(1):11-20. Epub 2016 Aug 30. Review.

PMID:
27575754
31.

Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities.

Bain CC, Hawley CA, Garner H, Scott CL, Schridde A, Steers NJ, Mack M, Joshi A, Guilliams M, Mowat AM, Geissmann F, Jenkins SJ.

Nat Commun. 2016 Jun 13;7:ncomms11852. doi: 10.1038/ncomms11852.

32.

The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2.

Scott CL, Soen B, Martens L, Skrypek N, Saelens W, Taminau J, Blancke G, Van Isterdael G, Huylebroeck D, Haigh J, Saeys Y, Guilliams M, Lambrecht BN, Berx G.

J Exp Med. 2016 May 30;213(6):897-911. doi: 10.1084/jem.20151715. Epub 2016 May 16.

33.

Isolation and Identification of Conventional Dendritic Cell Subsets from the Intestine of Mice and Men.

Scott CL, Wright PB, Milling SW, Mowat AM.

Methods Mol Biol. 2016;1423:101-18. doi: 10.1007/978-1-4939-3606-9_7.

PMID:
27142011
34.

Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages.

van de Laar L, Saelens W, De Prijck S, Martens L, Scott CL, Van Isterdael G, Hoffmann E, Beyaert R, Saeys Y, Lambrecht BN, Guilliams M.

Immunity. 2016 Apr 19;44(4):755-68. doi: 10.1016/j.immuni.2016.02.017. Epub 2016 Mar 15.

35.

BCL2-modifying factor promotes germ cell loss during murine oogenesis.

Vaithiyanathan K, Liew SH, Zerafa N, Gamage T, Cook M, O'Reilly LA, Bouillet P, Scott CL, Strasser A, Findlay JK, Hutt KJ.

Reproduction. 2016 May;151(5):553-62. doi: 10.1530/REP-15-0561. Epub 2016 Feb 25.

PMID:
26917450
36.

Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells.

Valente LJ, Aubrey BJ, Herold MJ, Kelly GL, Happo L, Scott CL, Newbold A, Johnstone RW, Huang DC, Vassilev LT, Strasser A.

Cell Rep. 2016 Mar 1;14(8):1858-66. doi: 10.1016/j.celrep.2016.01.059. Epub 2016 Feb 18.

37.

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells.

Scott CL, Zheng F, De Baetselier P, Martens L, Saeys Y, De Prijck S, Lippens S, Abels C, Schoonooghe S, Raes G, Devoogdt N, Lambrecht BN, Beschin A, Guilliams M.

Nat Commun. 2016 Jan 27;7:10321. doi: 10.1038/ncomms10321.

38.

Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer.

Bowtell DD, Böhm S, Ahmed AA, Aspuria PJ, Bast RC Jr, Beral V, Berek JS, Birrer MJ, Blagden S, Bookman MA, Brenton JD, Chiappinelli KB, Martins FC, Coukos G, Drapkin R, Edmondson R, Fotopoulou C, Gabra H, Galon J, Gourley C, Heong V, Huntsman DG, Iwanicki M, Karlan BY, Kaye A, Lengyel E, Levine DA, Lu KH, McNeish IA, Menon U, Narod SA, Nelson BH, Nephew KP, Pharoah P, Powell DJ Jr, Ramos P, Romero IL, Scott CL, Sood AK, Stronach EA, Balkwill FR.

Nat Rev Cancer. 2015 Nov;15(11):668-79. doi: 10.1038/nrc4019. Review.

39.

BCR-signaling-induced cell death demonstrates dependency on multiple BH3-only proteins in a murine model of B-cell lymphoma.

Carter MJ, Cox KL, Blakemore SJ, Bogdanov YD, Happo L, Scott CL, Strasser A, Packham GK, Cragg MS.

Cell Death Differ. 2016 Feb;23(2):303-12. doi: 10.1038/cdd.2015.97. Epub 2015 Jul 17.

40.

AAPL Practice Guideline for the Forensic Assessment.

Glancy GD, Ash P, Bath EP, Buchanan A, Fedoroff P, Frierson RL, Harris VL, Hatters Friedman SJ, Hauser MJ, Knoll J, Norko M, Pinals D, Price M, Recupero P, Scott CL, Zonana HV.

J Am Acad Psychiatry Law. 2015 Jun;43(2 Suppl):S3-53. Epub 2015 Jun 8. No abstract available.

PMID:
26054704
41.

Exploring metagenomics in the laboratory of an introductory biology course.

Gibbens BB, Scott CL, Hoff CD, Schottel JL.

J Microbiol Biol Educ. 2015 May 1;16(1):34-40. doi: 10.1128/jmbe.v16i1.780. eCollection 2015 May.

42.

Prioritizing therapeutic targets using patient-derived xenograft models.

Lodhia KA, Hadley AM, Haluska P, Scott CL.

Biochim Biophys Acta. 2015 Apr;1855(2):223-34. doi: 10.1016/j.bbcan.2015.03.002. Epub 2015 Mar 14. Review.

43.

Poly (ADP-ribose) polymerase inhibitors: recent advances and future development.

Scott CL, Swisher EM, Kaufmann SH.

J Clin Oncol. 2015 Apr 20;33(12):1397-406. doi: 10.1200/JCO.2014.58.8848. Epub 2015 Mar 16. Review.

44.

Mononuclear phagocytes of the intestine, the skin, and the lung.

Scott CL, Henri S, Guilliams M.

Immunol Rev. 2014 Nov;262(1):9-24. doi: 10.1111/imr.12220. Review.

PMID:
25319324
45.

Violence risk assessment and treatment.

Warburton KD, Scott CL.

CNS Spectr. 2014 Oct;19(5):366-7. doi: 10.1017/S1092852914000492. No abstract available.

PMID:
25296965
46.

mTOR signalling, embryogenesis and the control of lung development.

Land SC, Scott CL, Walker D.

Semin Cell Dev Biol. 2014 Dec;36:68-78. doi: 10.1016/j.semcdb.2014.09.023. Epub 2014 Oct 5. Review.

47.

Clinical assessment of psychotic and mood disorder symptoms for risk of future violence.

Scott CL, Resnick PJ.

CNS Spectr. 2014 Oct;19(5):474. No abstract available.

PMID:
27358937
48.

Clinical assessment of psychotic and mood disorder symptoms for risk of future violence.

Scott CL, Resnick PJ.

CNS Spectr. 2014 Oct;19(5):468-73. Review.

PMID:
27358936
49.

Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103(+) CD11b(+) DCs in the intestinal lamina propria.

Scott CL, Tfp ZM, Beckham KS, Douce G, Mowat AM.

Eur J Immunol. 2014 Dec;44(12):3658-68. doi: 10.1002/eji.201444859. Epub 2014 Oct 27.

50.

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice.

Bain CC, Bravo-Blas A, Scott CL, Perdiguero EG, Geissmann F, Henri S, Malissen B, Osborne LC, Artis D, Mowat AM.

Nat Immunol. 2014 Oct;15(10):929-937. doi: 10.1038/ni.2967. Epub 2014 Aug 24. Erratum in: Nat Immunol. 2014 Nov;15(11):1090.

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