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Small Molecule Potentiation of Gram-positive Selective Antibiotics Against Acinetobacter baumannii.

Martin S, Melander RJ, Brackett C, Scott AJ, Chandler CE, Nguyen C, Minrovic B, Harrill S, Ernst RK, Manoil C, Melander C.

ACS Infect Dis. 2019 Apr 19. doi: 10.1021/acsinfecdis.9b00067. [Epub ahead of print]


Increasing Incidence of Colon Cancer in the Young: Assessing the Tumor Biology.

Nfonsam VN, Jecius H, Chen D, Omesiete PN, Ewongwo AN, Elquza E, Scott AJ, Jandova J.

J Am Coll Surg. 2019 Apr 14. pii: S1072-7515(19)30257-1. doi: 10.1016/j.jamcollsurg.2019.03.022. [Epub ahead of print]


Supporting medication adherence for adults with cystic fibrosis: a randomised feasibility study.

Hind D, Drabble SJ, Arden MA, Mandefield L, Waterhouse S, Maguire C, Cantrill H, Robinson L, Beever D, Scott AJ, Keating S, Hutchings M, Bradley J, Nightingale J, Allenby MI, Dewar J, Whelan P, Ainsworth J, Walters SJ, O'Cathain A, Wildman MJ.

BMC Pulm Med. 2019 Apr 11;19(1):77. doi: 10.1186/s12890-019-0834-6.


Genomic Analysis in the Age of Human Genome Sequencing.

Lappalainen T, Scott AJ, Brandt M, Hall IM.

Cell. 2019 Mar 21;177(1):70-84. doi: 10.1016/j.cell.2019.02.032. Review.


Quality of life after total laryngectomy: evaluating the effect of socioeconomic status.

Scott AJ, McGuire JK, Manning K, Leach L, Fagan JJ.

J Laryngol Otol. 2019 Feb;133(2):129-134. doi: 10.1017/S0022215119000215. Epub 2019 Feb 18.


Prospective Study of Psychological Morbidity and Illness Perceptions in Young People with Inflammatory Bowel Disease.

Brooks AJ, Norman P, Peach EJ, Ryder AH, Scott AJ, Narula P, Corfe BM, Lobo AJ, Rowse G.

J Crohns Colitis. 2019 Feb 5. doi: 10.1093/ecco-jcc/jjz028. [Epub ahead of print]


Bacterial sensors define intracellular free energies for correct enzyme metalation.

Osman D, Martini MA, Foster AW, Chen J, Scott AJP, Morton RJ, Steed JW, Lurie-Luke E, Huggins TG, Lawrence AD, Deery E, Warren MJ, Chivers PT, Robinson NJ.

Nat Chem Biol. 2019 Mar;15(3):241-249. doi: 10.1038/s41589-018-0211-4. Epub 2019 Jan 28.


A cluster randomized controlled trial of a theory-based sleep hygiene intervention for adolescents.

Lin CY, Strong C, Scott AJ, Broström A, Pakpour AH, Webb TL.

Sleep. 2018 Nov 1;41(11). doi: 10.1093/sleep/zsy170.


Pre-, pro- and synbiotics in cancer prevention and treatment-a review of basic and clinical research.

Scott AJ, Merrifield CA, Younes JA, Pekelharing EP.

Ecancermedicalscience. 2018 Sep 5;12:869. doi: 10.3332/ecancer.2018.869. eCollection 2018. Review.


Gut microbiota, chemotherapy and the host: the influence of the gut microbiota on cancer treatment.

Pouncey AL, Scott AJ, Alexander JL, Marchesi J, Kinross J.

Ecancermedicalscience. 2018 Sep 5;12:868. doi: 10.3332/ecancer.2018.868. eCollection 2018. Review.


Colorectal carcinogenesis: an archetype of gut microbiota-host interaction.

Alexander JL, Scott AJ, Pouncey AL, Marchesi J, Kinross J, Teare J.

Ecancermedicalscience. 2018 Sep 5;12:865. doi: 10.3332/ecancer.2018.865. eCollection 2018. Review.


The Viability of Percutaneous Bone-Anchored Hearing Systems in the HIV Population.

Kuschke S, Honnet S, Scott AJ, Labuschagne S, Pithey S, Solomons Z, Meyer E.

Otol Neurotol. 2018 Dec;39(10):e1064-e1068. doi: 10.1097/MAO.0000000000002007.


Clinical and cost-effectiveness of one-session treatment (OST) versus multisession cognitive-behavioural therapy (CBT) for specific phobias in children: protocol for a non-inferiority randomised controlled trial.

Wright BD, Cooper C, Scott AJ, Tindall L, Ali S, Bee P, Biggs K, Breckman T, Davis Iii TE, Gega L, Hargate RJ, Lee E, Lovell K, Marshall D, McMillan D, Teare MD, Wilson J.

BMJ Open. 2018 Aug 17;8(8):e025031. doi: 10.1136/bmjopen-2018-025031.


AIF promotes a JNK1-mediated cadherin switch independently of respiratory chain stabilization.

Scott AJ, Walker SA, Krank JJ, Wilkinson AS, Johnson KM, Lewis EM, Wilkinson JC.

J Biol Chem. 2018 Sep 21;293(38):14707-14722. doi: 10.1074/jbc.RA118.004022. Epub 2018 Aug 9.


A single-arm, retrospective analysis of the incidence of febrile neutropenia using same-day versus next-day pegfilgrastim in patients with gastrointestinal cancers treated with FOLFOX or FOLFIRI.

Eckstrom J, Bartels T, Abraham I, Patel H, Elquza E, Scott AJ, Malangone S, Hollings J, McBride A.

Support Care Cancer. 2019 Mar;27(3):873-878. doi: 10.1007/s00520-018-4373-0. Epub 2018 Aug 8.


Cabozantinib Exhibits Potent Antitumor Activity in Colorectal Cancer Patient-Derived Tumor Xenograft Models via Autophagy and Signaling Mechanisms.

Scott AJ, Arcaroli JJ, Bagby SM, Yahn R, Huber KM, Serkova NJ, Nguyen A, Kim J, Thorburn A, Vogel J, Quackenbush KS, Capasso A, Schreiber A, Blatchford P, Klauck PJ, Pitts TM, Eckhardt SG, Messersmith WA.

Mol Cancer Ther. 2018 Oct;17(10):2112-2122. doi: 10.1158/1535-7163.MCT-17-0131. Epub 2018 Jul 19.


In Vivo Intradermal Delivery of Bacteria by Using Microneedle Arrays.

Chandler CE, Harberts EM, Laemmermann T, Zeng Q, Opene BN, Germain RN, Jewell CM, Scott AJ, Ernst RK.

Infect Immun. 2018 Aug 22;86(9). pii: e00406-18. doi: 10.1128/IAI.00406-18. Print 2018 Sep.


Prospective Risk Factor Analysis for the Development of Post-operative Urinary Retention Following Ambulatory General Surgery.

Scott AJ, Mason SE, Langdon AJ, Patel B, Mayer E, Moorthy K, Purkayastha S.

World J Surg. 2018 Dec;42(12):3874-3879. doi: 10.1007/s00268-018-4697-4.


A qualitative examination and theoretical model of anxiety in adults with epilepsy.

Scott AJ, Sharpe L, Thayer Z, Miller LA, Wong T, Parratt K, Nikpour A.

Epilepsy Behav. 2018 Aug;85:95-104. doi: 10.1016/j.yebeh.2018.05.023. Epub 2018 Jun 19.


Highlights from the Inaugural International Cancer Microbiome Consortium Meeting (ICMC), 5-6 September 2017, London, UK.

Scott AJ, Merrifield CA, Alexander JL, Marchesi JR, Kinross JM.

Ecancermedicalscience. 2017 Dec 20;11:791. doi: 10.3332/ecancer.2017.791. eCollection 2017.


Host-based lipid inflammation drives pathogenesis in Francisella infection.

Scott AJ, Post JM, Lerner R, Ellis SR, Lieberman J, Shirey KA, Heeren RMA, Bindila L, Ernst RK.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12596-12601. doi: 10.1073/pnas.1712887114. Epub 2017 Nov 6.


Evaluation of the efficacy of dasatinib, a Src/Abl inhibitor, in colorectal cancer cell lines and explant mouse model.

Scott AJ, Song EK, Bagby S, Purkey A, McCarter M, Gajdos C, Quackenbush KS, Cross B, Pitts TM, Tan AC, Eckhardt SG, Fenton H, Arcaroli J, Messersmith WA.

PLoS One. 2017 Nov 1;12(11):e0187173. doi: 10.1371/journal.pone.0187173. eCollection 2017.


A structural equation model of the relationship between insomnia, negative affect, and paranoid thinking.

Scott AJ, Rowse G, Webb TL.

PLoS One. 2017 Oct 19;12(10):e0186233. doi: 10.1371/journal.pone.0186233. eCollection 2017.


The impact of rare variation on gene expression across tissues.

Li X, Kim Y, Tsang EK, Davis JR, Damani FN, Chiang C, Hess GT, Zappala Z, Strober BJ, Scott AJ, Li A, Ganna A, Bassik MC, Merker JD; GTEx Consortium; Laboratory, Data Analysis &Coordinating Center (LDACC)—Analysis Working Group; Statistical Methods groups—Analysis Working Group; Enhancing GTEx (eGTEx) groups; NIH Common Fund; NIH/NCI; NIH/NHGRI; NIH/NIMH; NIH/NIDA; Biospecimen Collection Source Site—NDRI; Biospecimen Collection Source Site—RPCI; Biospecimen Core Resource—VARI; Brain Bank Repository—University of Miami Brain Endowment Bank; Leidos Biomedical—Project Management; ELSI Study; Genome Browser Data Integration &Visualization—EBI; Genome Browser Data Integration &Visualization—UCSC Genomics Institute, University of California Santa Cruz, Hall IM, Battle A, Montgomery SB.

Nature. 2017 Oct 11;550(7675):239-243. doi: 10.1038/nature24267.


Does improving sleep lead to better mental health? A protocol for a meta-analytic review of randomised controlled trials.

Scott AJ, Webb TL, Rowse G.

BMJ Open. 2017 Sep 18;7(9):e016873. doi: 10.1136/bmjopen-2017-016873.


The International Association of Student Surgical Societies: A brief history from 2014-2017.

Booth A, Burger S, Scott AJ, Thomson D.

S Afr J Surg. 2017 Jun;55(2):2-5.


The Semantics of Priapism and the First Sign of Chronic Myeloid Leukemia.

Minckler MR, Conser E, Figueroa JJ, Scott AJ, Gaither J, Amini R.

Case Rep Emerg Med. 2017;2017:2656203. doi: 10.1155/2017/2656203. Epub 2017 May 30.


Female undergraduate's perceptions of intrusive behavior in 12 countries.

Sheridan L, Scott AJ, Archer J, Roberts K.

Aggress Behav. 2017 Nov;43(6):531-543. doi: 10.1002/ab.21711. Epub 2017 May 15.


QT interval prolongation in opioid agonist treatment: analysis of continuous 12-lead electrocardiogram recordings.

Isbister GK, Brown AL, Gill A, Scott AJ, Calver L, Dunlop AJ.

Br J Clin Pharmacol. 2017 Oct;83(10):2274-2282. doi: 10.1111/bcp.13326. Epub 2017 Jun 14.


Anxiety and depressive disorders in people with epilepsy: A meta-analysis.

Scott AJ, Sharpe L, Hunt C, Gandy M.

Epilepsia. 2017 Jun;58(6):973-982. doi: 10.1111/epi.13769. Epub 2017 May 3.


Assessment of sun-protective attitudes and behaviours of australian medical students.

Scott AJ, Harris V, Lee A, Smith SD.

J Eur Acad Dermatol Venereol. 2017 Nov;31(11):e497-e498. doi: 10.1111/jdv.14298. Epub 2017 May 22. No abstract available.


Longitudinal analysis of serum oxylipin profile as a novel descriptor of the inflammatory response to surgery.

Wolfer AM, Scott AJ, Rueb C, Gaudin M, Darzi A, Nicholson JK, Holmes E, Kinross JM.

J Transl Med. 2017 Apr 26;15(1):83. doi: 10.1186/s12967-017-1171-2.


Prevalence and risk factors of nonalcoholic fatty liver disease in HIV-monoinfection.

Maurice JB, Patel A, Scott AJ, Patel K, Thursz M, Lemoine M.

AIDS. 2017 Jul 17;31(11):1621-1632. doi: 10.1097/QAD.0000000000001504. Review.


Robust theoretical modelling of core ionisation edges for quantitative electron energy loss spectroscopy of B- and N-doped graphene.

Hardcastle TP, Seabourne CR, Kepaptsoglou DM, Susi T, Nicholls RJ, Brydson RMD, Scott AJ, Ramasse QM.

J Phys Condens Matter. 2017 Jun 7;29(22):225303. doi: 10.1088/1361-648X/aa6c4f. Epub 2017 Apr 10.


The impact of structural variation on human gene expression.

Chiang C, Scott AJ, Davis JR, Tsang EK, Li X, Kim Y, Hadzic T, Damani FN, Ganel L; GTEx Consortium, Montgomery SB, Battle A, Conrad DF, Hall IM.

Nat Genet. 2017 May;49(5):692-699. doi: 10.1038/ng.3834. Epub 2017 Apr 3.


Infection-derived lipids elicit an immune deficiency circuit in arthropods.

Shaw DK, Wang X, Brown LJ, Chávez AS, Reif KE, Smith AA, Scott AJ, McClure EE, Boradia VM, Hammond HL, Sundberg EJ, Snyder GA, Liu L, DePonte K, Villar M, Ueti MW, de la Fuente J, Ernst RK, Pal U, Fikrig E, Pedra JH.

Nat Commun. 2017 Feb 14;8:14401. doi: 10.1038/ncomms14401.


A tight tunable range for Ni(II) sensing and buffering in cells.

Foster AW, Pernil R, Patterson CJ, Scott AJP, Pålsson LO, Pal R, Cummins I, Chivers PT, Pohl E, Robinson NJ.

Nat Chem Biol. 2017 Apr;13(4):409-414. doi: 10.1038/nchembio.2310. Epub 2017 Feb 6.


Lipid A structural modifications in extreme conditions and identification of unique modifying enzymes to define the Toll-like receptor 4 structure-activity relationship.

Scott AJ, Oyler BL, Goodlett DR, Ernst RK.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Nov;1862(11):1439-1450. doi: 10.1016/j.bbalip.2017.01.004. Epub 2017 Jan 17. Review.


Global Analysis and Comparison of the Transcriptomes and Proteomes of Group A Streptococcus Biofilms.

Freiberg JA, Le Breton Y, Tran BQ, Scott AJ, Harro JM, Ernst RK, Goo YA, Mongodin EF, Goodlett DR, McIver KS, Shirtliff ME.

mSystems. 2016 Dec 6;1(6). pii: e00149-16. eCollection 2016 Nov-Dec.


Norharmane Matrix Enhances Detection of Endotoxin by MALDI-MS for Simultaneous Profiling of Pathogen, Host, and Vector Systems.

Scott AJ, Flinders B, Cappell J, Liang T, Pelc RS, Tran B, Kilgour DP, Heeren RM, Goodlett DR, Ernst RK.

Pathog Dis. 2016 Sep 19. pii: ftw097. [Epub ahead of print]


HNF1A, KRT81, and CYP3A5: three more straws on the back of pancreatic cancer?

Scott AJ, Wilkinson JC.

Transl Cancer Res. 2016 Aug;5(Suppl 2):S253-S256. doi: 10.21037/tcr.2016.08.12. No abstract available.


Type IV pili promote early biofilm formation by Clostridium difficile.

Maldarelli GA, Piepenbrink KH, Scott AJ, Freiberg JA, Song Y, Achermann Y, Ernst RK, Shirtliff ME, Sundberg EJ, Donnenberg MS, von Rosenvinge EC.

Pathog Dis. 2016 Aug;74(6). pii: ftw061. doi: 10.1093/femspd/ftw061. Epub 2016 Jun 30.


Therapeutic Approaches to RAS Mutation.

Scott AJ, Lieu CH, Messersmith WA.

Cancer J. 2016 May-Jun;22(3):165-74. doi: 10.1097/PPO.0000000000000187. Review.


The prevalence of QT prolongation in a population of patients with substance use disorders.

Scott AJ, Dunlop AJ, Brown A, Sadler C, Isbister GK.

Drug Alcohol Rev. 2017 Mar;36(2):239-244. doi: 10.1111/dar.12415. Epub 2016 May 30.


Perceptions and Experiences of Intrusive Behavior and Stalking: Comparing LGBTIQ and Heterosexual Groups.

Sheridan LP, Scott AJ, Campbell AM.

J Interpers Violence. 2019 Apr;34(7):1388-1409. doi: 10.1177/0886260516651313. Epub 2016 May 27.


Apoptosis Inducing Factor Binding Protein PGAM5 Triggers Mitophagic Cell Death That Is Inhibited by the Ubiquitin Ligase Activity of X-Linked Inhibitor of Apoptosis.

Lenhausen AM, Wilkinson AS, Lewis EM, Dailey KM, Scott AJ, Khan S, Wilkinson JC.

Biochemistry. 2016 Jun 14;55(23):3285-302. doi: 10.1021/acs.biochem.6b00306. Epub 2016 Jun 2.


Bioequivalence and comparative pharmacodynamics of insulin lispro 200 U/mL relative to insulin lispro (Humalog®) 100 U/mL.

de la Peña A, Seger M, Soon D, Scott AJ, Reddy SR, Dobbins MA, Brown-Augsburger P, Linnebjerg H.

Clin Pharmacol Drug Dev. 2016 Jan;5(1):69-75. doi: 10.1002/cpdd.221. Epub 2015 Oct 5.


Basal metabolic state governs AIF-dependent growth support in pancreatic cancer cells.

Scott AJ, Wilkinson AS, Wilkinson JC.

BMC Cancer. 2016 Apr 23;16:286. doi: 10.1186/s12885-016-2320-3.


A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer.

O'Neil BH, Scott AJ, Ma WW, Cohen SJ, Aisner DL, Menter AR, Tejani MA, Cho JK, Granfortuna J, Coveler AL, Olowokure OO, Baranda JC, Cusnir M, Phillip P, Boles J, Nazemzadeh R, Rarick M, Cohen DJ, Radford J, Fehrenbacher L, Bajaj R, Bathini V, Fanta P, Berlin J, McRee AJ, Maguire R, Wilhelm F, Maniar M, Jimeno A, Gomes CL, Messersmith WA.

Ann Oncol. 2016 Jun;27(6):1180. doi: 10.1093/annonc/mdw095. Epub 2016 Mar 3. No abstract available.


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