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Items: 1 to 50 of 314

1.

Uncovering the clinical impact of kallikrein-related peptidase 5 (KLK5) mRNA expression in the colorectal adenoma-carcinoma sequence.

Papachristopoulou G, Malachias A, Devetzi M, Kamouza E, Scorilas A, Xynopoulos D, Talieri M.

Clin Chem Lab Med. 2019 Feb 13. pii: /j/cclm.ahead-of-print/cclm-2018-1010/cclm-2018-1010.xml. doi: 10.1515/cclm-2018-1010. [Epub ahead of print]

PMID:
30759066
2.

Blood-based analysis of type-2 diabetes mellitus susceptibility genes identifies specific transcript variants with deregulated expression and association with disease risk.

Christodoulou MI, Avgeris M, Kokkinopoulou I, Maratou E, Mitrou P, Kontos CK, Pappas E, Boutati E, Scorilas A, Fragoulis EG.

Sci Rep. 2019 Feb 6;9(1):1512. doi: 10.1038/s41598-018-37856-1.

3.

The lysine-specific methyltransferase KMT2C/MLL3 regulates DNA repair components in cancer.

Rampias T, Karagiannis D, Avgeris M, Polyzos A, Kokkalis A, Kanaki Z, Kousidou E, Tzetis M, Kanavakis E, Stravodimos K, Manola KN, Pantelias GE, Scorilas A, Klinakis A.

EMBO Rep. 2019 Jan 21. pii: e46821. doi: 10.15252/embr.201846821. [Epub ahead of print]

PMID:
30665945
4.

Molecular Effects of Treatment of Human Colorectal Cancer Cells with Natural and Classical Chemotherapeutic Drugs: Alterations in the Expression of Apoptosis-related BCL2 Family Members, Including BCL2L12.

Kontos CK, Avgeris M, Vassilacopoulou D, Ardavanis A, Scorilas A.

Curr Pharm Biotechnol. 2018;19(13):1064-1075. doi: 10.2174/1389201019666181112101410.

PMID:
30417787
5.

Evidence for L-Dopa Decarboxylase Involvement in Cancer Cell Cytotoxicity Induced by Docetaxel and Mitoxantrone.

Kalantzis ED, Scorilas A, Vassilacopoulou D.

Curr Pharm Biotechnol. 2018;19(13):1087-1096. doi: 10.2174/1389201019666181112103637.

PMID:
30417785
6.

Loss of GAS5 tumour suppressor lncRNA: an independent molecular cancer biomarker for short-term relapse and progression in bladder cancer patients.

Avgeris M, Tsilimantou A, Levis PK, Tokas T, Sideris DC, Stravodimos K, Ardavanis A, Scorilas A.

Br J Cancer. 2018 Dec;119(12):1477-1486. doi: 10.1038/s41416-018-0320-6. Epub 2018 Oct 30.

PMID:
30374124
7.

Clinical utility of microRNAs in renal cell carcinoma: current evidence and future perspectives.

Tsiakanikas P, Giaginis C, Kontos CK, Scorilas A.

Expert Rev Mol Diagn. 2018 Nov;18(11):981-991. doi: 10.1080/14737159.2018.1539668. Epub 2018 Oct 26.

PMID:
30345829
8.

miRNA and long non-coding RNA: molecular function and clinical value in breast and ovarian cancers.

Panoutsopoulou K, Avgeris M, Scorilas A.

Expert Rev Mol Diagn. 2018 Nov;18(11):963-979. doi: 10.1080/14737159.2018.1538794. Epub 2018 Oct 29.

PMID:
30338716
9.

BCL2L12: a multiply spliced gene with independent prognostic significance in breast cancer.

Kladi-Skandali A, Sideris DC, Scorilas A.

Clin Chem Lab Med. 2018 Dec 19;57(2):276-287. doi: 10.1515/cclm-2018-0272.

PMID:
30325729
10.

The International Society for Enzymology: a glorious history, a golden legacy.

Diamandis EP, Scorilas A, Prassas I, Plebani M.

Clin Chem Lab Med. 2018 Oct 25;56(11):275-276. doi: 10.1515/cclm-2018-0766. No abstract available.

PMID:
30157030
11.

Molecular cloning of novel transcripts of the adaptor-related protein complex 2 alpha 1 subunit (AP2A1) gene, using Next-Generation Sequencing.

Adamopoulos PG, Kontos CK, Diamantopoulos MA, Scorilas A.

Gene. 2018 Dec 15;678:55-64. doi: 10.1016/j.gene.2018.08.008. Epub 2018 Aug 4.

PMID:
30081190
12.

Alternative Splicing Detection Tool-a novel PERL algorithm for sensitive detection of splicing events, based on next-generation sequencing data analysis.

Adamopoulos PG, Theodoropoulou MC, Scorilas A.

Ann Transl Med. 2018 Jun;6(12):244. doi: 10.21037/atm.2018.06.32.

13.

Quantitative analysis and study of the mRNA expression levels of apoptotic genes BCL2, BAX and BCL2L12 in the articular cartilage of an animal model of osteoarthritis.

Kourtis A, Adamopoulos PG, Papalois A, Iliopoulos DC, Babis GC, Scorilas A.

Ann Transl Med. 2018 Jun;6(12):243. doi: 10.21037/atm.2018.05.47.

14.

Non-coding RNAs: the riddle of the transcriptome and their perspectives in cancer.

Diamantopoulos MA, Tsiakanikas P, Scorilas A.

Ann Transl Med. 2018 Jun;6(12):241. doi: 10.21037/atm.2018.06.10. Review.

15.

A comprehensive clinicopathological evaluation of the differential expression of microRNA-331 in breast tumors and its diagnostic significance.

Papadopoulos EI, Papachristopoulou G, Ardavanis A, Scorilas A.

Clin Biochem. 2018 Sep;60:24-32. doi: 10.1016/j.clinbiochem.2018.07.008. Epub 2018 Jul 29.

PMID:
30063890
16.

Expressional profiling and clinical relevance of RNase κ in prostate cancer: a novel indicator of favorable progression-free survival.

Kladi-Skandali A, Mavridis K, Scorilas A, Sideris DC.

J Cancer Res Clin Oncol. 2018 Oct;144(10):2049-2057. doi: 10.1007/s00432-018-2719-0. Epub 2018 Jul 27.

PMID:
30054827
17.

BCL2L12 improves risk stratification and prediction of BFM-chemotherapy response in childhood acute lymphoblastic leukemia.

Avgeris M, Stamati L, Kontos CK, Piatopoulou D, Marmarinos A, Xagorari M, Baka M, Doganis D, Anastasiou T, Kosmidis H, Gourgiotis D, Scorilas A.

Clin Chem Lab Med. 2018 Nov 27;56(12):2104-2118. doi: 10.1515/cclm-2018-0507.

PMID:
30016275
18.

MicroRNA-92a-3p overexpression in peripheral blood mononuclear cells is an independent predictor of prolonged overall survival of patients with chronic lymphocytic leukemia.

Papageorgiou SG, Diamantopoulos MA, Kontos CK, Bouchla A, Vasilatou D, Bazani E, Scorilas A, Pappa V.

Leuk Lymphoma. 2018 Jun 18:1-10. doi: 10.1080/10428194.2018.1461861. [Epub ahead of print]

PMID:
29911923
19.

Kallikrein-related peptidases and associated microRNAs as promising prognostic biomarkers in gastrointestinal malignancies.

Adamopoulos PG, Tsiakanikas P, Scorilas A.

Biol Chem. 2018 Jul 26;399(8):821-836. doi: 10.1515/hsz-2017-0342. Review.

PMID:
29883317
20.

Novel splice variants of the human kallikrein-related peptidases 11 (KLK11) and 12 (KLK12), unraveled by next-generation sequencing technology.

Adamopoulos PG, Kontos CK, Scorilas A.

Biol Chem. 2018 Sep 25;399(9):1065-1071. doi: 10.1515/hsz-2017-0294.

PMID:
29874189
21.

Human kallikrein-related peptidase 12 (KLK12) splice variants discriminate benign from cancerous breast tumors.

Papachristopoulou G, Tsapralis N, Michaelidou K, Ardavanis-Loukeris G, Griniatsos I, Scorilas A, Talieri M.

Clin Biochem. 2018 Aug;58:78-85. doi: 10.1016/j.clinbiochem.2018.05.017. Epub 2018 May 25.

PMID:
29807016
22.

Discovery and expression analysis of novel transcripts of the human SR-related CTD-associated factor 1 (SCAF1) gene in human cancer cells using Next-Generation Sequencing.

Adamopoulos PG, Raptis GD, Kontos CK, Scorilas A.

Gene. 2018 Sep 5;670:155-165. doi: 10.1016/j.gene.2018.05.044. Epub 2018 May 19.

PMID:
29787824
23.

Elevated miR-20b-5p expression in peripheral blood mononuclear cells: A novel, independent molecular biomarker of favorable prognosis in chronic lymphocytic leukemia.

Papageorgiou SG, Kontos CK, Tsiakanikas P, Stavroulaki G, Bouchla A, Vasilatou D, Bazani E, Lazarakou A, Scorilas A, Pappa V.

Leuk Res. 2018 Apr 26;70:1-7. doi: 10.1016/j.leukres.2018.04.014. [Epub ahead of print]

PMID:
29715621
24.

Natural alkaloids intervening the insulin pathway: new hopes for anti-diabetic agents?

Christodoulou MI, Tchoumtchoua J, Skaltsounis AL, Scorilas A, Halabalaki M.

Curr Med Chem. 2018 Apr 30. doi: 10.2174/0929867325666180430152618. [Epub ahead of print]

PMID:
29714135
25.

High microRNA-28-5p expression in colorectal adenocarcinoma predicts short-term relapse of node-negative patients and poor overall survival of patients with non-metastatic disease.

Tsiakanikas P, Kontos CK, Kerimis D, Papadopoulos IN, Scorilas A.

Clin Chem Lab Med. 2018 May 24;56(6):990-1000. doi: 10.1515/cclm-2017-0430.

PMID:
29688883
26.

Discovery of novel transcripts of the human tissue kallikrein (KLK1) and kallikrein-related peptidase 2 (KLK2) in human cancer cells, exploiting Next-Generation Sequencing technology.

Adamopoulos PG, Kontos CK, Scorilas A.

Genomics. 2018 Mar 31. pii: S0888-7543(18)30206-4. doi: 10.1016/j.ygeno.2018.03.022. [Epub ahead of print]

PMID:
29614347
27.

Manfred Schmitt (1947-2018).

Reuning U, Magdolen V, Courty Y, Clements JA, Yousef GM, Scorilas A, Talieri M, Diamandis EP.

Biol Chem. 2018 Sep 25;399(9):923-924. doi: 10.1515/hsz-2018-0184. No abstract available.

PMID:
29601294
28.

Clinical utility of miR-143/miR-182 levels in prognosis and risk stratification specificity of BFM-treated childhood acute lymphoblastic leukemia.

Piatopoulou D, Avgeris M, Drakaki I, Marmarinos A, Xagorari M, Baka M, Pourtsidis A, Kossiva L, Gourgiotis D, Scorilas A.

Ann Hematol. 2018 Jul;97(7):1169-1182. doi: 10.1007/s00277-018-3292-y. Epub 2018 Mar 20.

PMID:
29556721
29.

MicroRNA-155-5p Overexpression in Peripheral Blood Mononuclear Cells of Chronic Lymphocytic Leukemia Patients Is a Novel, Independent Molecular Biomarker of Poor Prognosis.

Papageorgiou SG, Kontos CK, Diamantopoulos MA, Bouchla A, Glezou E, Bazani E, Pappa V, Scorilas A.

Dis Markers. 2017;2017:2046545. doi: 10.1155/2017/2046545. Epub 2017 Dec 31.

30.

Kallikrein-related peptidase 6 (KLK6) expression differentiates tumor subtypes and predicts clinical outcome in breast cancer patients.

Haritos C, Michaelidou K, Mavridis K, Missitzis I, Ardavanis A, Griniatsos J, Scorilas A.

Clin Exp Med. 2018 May;18(2):203-213. doi: 10.1007/s10238-018-0487-4. Epub 2018 Feb 12.

PMID:
29435805
31.

Expression Analysis of miR-29b in Malignant and Benign Breast Tumors: A Promising Prognostic Biomarker for Invasive Ductal Carcinoma With a Possible Histotype-Related Expression Status.

Papachristopoulou G, Papadopoulos EI, Nonni A, Rassidakis GZ, Scorilas A.

Clin Breast Cancer. 2018 Aug;18(4):305-312.e3. doi: 10.1016/j.clbc.2017.11.007. Epub 2017 Nov 21.

PMID:
29422258
32.

Molecular cloning of novel transcripts of human kallikrein-related peptidases 5, 6, 7, 8 and 9 (KLK5 - KLK9), using Next-generation sequencing.

Adamopoulos PG, Kontos CK, Scorilas A.

Sci Rep. 2017 Dec 11;7(1):17299. doi: 10.1038/s41598-017-16269-6.

33.

miR-221/222 cluster expression improves clinical stratification of non-muscle invasive bladder cancer (TaT1) patients' risk for short-term relapse and progression.

Tsikrika FD, Avgeris M, Levis PK, Tokas T, Stravodimos K, Scorilas A.

Genes Chromosomes Cancer. 2018 Mar;57(3):150-161. doi: 10.1002/gcc.22516. Epub 2017 Dec 15.

PMID:
29181884
34.

Multianalyte quantitative competitive PCR on optically encoded microspheres for an eight-gene panel related to prostate cancer.

Kyriakou IK, Mavridis K, Kalogianni DP, Christopoulos TK, Ioannou PC, Scorilas A.

Anal Bioanal Chem. 2018 Jan;410(3):971-980. doi: 10.1007/s00216-017-0595-0. Epub 2017 Aug 31.

PMID:
28861591
35.

miR-125b predicts childhood acute lymphoblastic leukaemia poor response to BFM chemotherapy treatment.

Piatopoulou D, Avgeris M, Marmarinos A, Xagorari M, Baka M, Doganis D, Kossiva L, Scorilas A, Gourgiotis D.

Br J Cancer. 2017 Sep 5;117(6):801-812. doi: 10.1038/bjc.2017.256. Epub 2017 Aug 8.

36.

The transcriptome of a "sleeping" invader: de novo assembly and annotation of the transcriptome of aestivating Cornu aspersum.

Parmakelis A, Kotsakiozi P, Kontos CK, Adamopoulos PG, Scorilas A.

BMC Genomics. 2017 Jun 28;18(1):491. doi: 10.1186/s12864-017-3885-1.

37.

miR-34a overexpression predicts poor prognostic outcome in colorectal adenocarcinoma, independently of clinicopathological factors with established prognostic value.

Rapti SM, Kontos CK, Christodoulou S, Papadopoulos IN, Scorilas A.

Clin Biochem. 2017 Nov;50(16-17):918-924. doi: 10.1016/j.clinbiochem.2017.06.004. Epub 2017 Jun 15.

PMID:
28624481
38.

Identification and molecular cloning of novel transcripts of the human kallikrein-related peptidase 10 (KLK10) gene using next-generation sequencing.

Adamopoulos PG, Kontos CK, Scorilas A.

Biochem Biophys Res Commun. 2017 Jun 10;487(4):776-781. doi: 10.1016/j.bbrc.2017.04.078. Epub 2017 Apr 15.

PMID:
28419837
39.

miR-15a-5p, A Novel Prognostic Biomarker, Predicting Recurrent Colorectal Adenocarcinoma.

Kontos CK, Tsiakanikas P, Avgeris M, Papadopoulos IN, Scorilas A.

Mol Diagn Ther. 2017 Aug;21(4):453-464. doi: 10.1007/s40291-017-0270-3.

PMID:
28405803
40.

Pediatric Ependymoma: A Proteomics Perspective.

Tsangaris GT, Papathanasiou C, Adamopoulos PG, Scorilas A, Vorgias CE, Prodromou N, Stathopoulou FT, Stravopodis DJ, Anagnostopoulos AK.

Cancer Genomics Proteomics. 2017 Mar-Apr;14(2):127-136.

41.

miR-10b is a prognostic marker in clear cell renal cell carcinoma.

Khella HWZ, Daniel N, Youssef L, Scorilas A, Nofech-Mozes R, Mirham L, Krylov SN, Liandeau E, Krizova A, Finelli A, Cheng Y, Yousef GM.

J Clin Pathol. 2017 Oct;70(10):854-859. doi: 10.1136/jclinpath-2017-204341. Epub 2017 Mar 30.

PMID:
28360191
42.

Galectin-1 has potential prognostic significance and is implicated in clear cell renal cell carcinoma progression through the HIF/mTOR signaling axis.

White NM, Masui O, Newsted D, Scorilas A, Romaschin AD, Bjarnason GA, Siu KW, Yousef GM.

Br J Cancer. 2017 Mar 14;116(6):e3. doi: 10.1038/bjc.2016.441. Epub 2017 Jan 12. No abstract available.

43.

mRNA overexpression of the hypoxia inducible factor 1 alpha subunit gene (HIF1A): An independent predictor of poor overall survival in chronic lymphocytic leukemia.

Kontos CK, Papageorgiou SG, Diamantopoulos MA, Scorilas A, Bazani E, Vasilatou D, Gkontopoulos K, Glezou E, Stavroulaki G, Dimitriadis G, Pappa V.

Leuk Res. 2017 Feb;53:65-73. doi: 10.1016/j.leukres.2016.11.014. Epub 2016 Nov 29.

PMID:
28038356
44.

Assessing the clinical value of microRNAs in formalin-fixed paraffin-embedded liposarcoma tissues: Overexpressed miR-155 is an indicator of poor prognosis.

Kapodistrias N, Mavridis K, Batistatou A, Gogou P, Karavasilis V, Sainis I, Briasoulis E, Scorilas A.

Oncotarget. 2017 Jan 24;8(4):6896-6913. doi: 10.18632/oncotarget.14320.

45.

Elevated expression of miR-24-3p is a potentially adverse prognostic factor in colorectal adenocarcinoma.

Kerimis D, Kontos CK, Christodoulou S, Papadopoulos IN, Scorilas A.

Clin Biochem. 2017 Apr;50(6):285-292. doi: 10.1016/j.clinbiochem.2016.11.034. Epub 2016 Dec 7.

PMID:
27939727
46.

Upregulated miR-16 expression is an independent indicator of relapse and poor overall survival of colorectal adenocarcinoma patients.

Diamantopoulos MA, Kontos CK, Kerimis D, Papadopoulos IN, Scorilas A.

Clin Chem Lab Med. 2017 May 1;55(5):737-747. doi: 10.1515/cclm-2016-0756.

PMID:
27930363
47.

Unravelling a p73-regulated network: The role of a novel p73-dependent target, MIR3158, in cancer cell migration and invasiveness.

Galtsidis S, Logotheti S, Pavlopoulou A, Zampetidis CP, Papachristopoulou G, Scorilas A, Vojtesek B, Gorgoulis V, Zoumpourlis V.

Cancer Lett. 2017 Mar 1;388:96-106. doi: 10.1016/j.canlet.2016.11.036. Epub 2016 Dec 3.

PMID:
27919789
48.

Downregulated KLK13 expression in bladder cancer highlights tumor aggressiveness and unfavorable patients' prognosis.

Tokas T, Avgeris M, Alamanis C, Scorilas A, Stravodimos KG, Constantinides CA.

J Cancer Res Clin Oncol. 2017 Mar;143(3):521-532. doi: 10.1007/s00432-016-2301-6. Epub 2016 Nov 17.

PMID:
27858162
49.

High miR-96 levels in colorectal adenocarcinoma predict poor prognosis, particularly in patients without distant metastasis at the time of initial diagnosis.

Rapti SM, Kontos CK, Papadopoulos IN, Scorilas A.

Tumour Biol. 2016 Sep;37(9):11815-11824. Epub 2016 Apr 4.

PMID:
27044381
50.

Metformin and Anti-Cancer Therapeutics: Hopes for a More Enhanced Armamentarium Against Human Neoplasias?

Christodoulou MI, Scorilas A.

Curr Med Chem. 2017;24(1):14-56. doi: 10.2174/0929867323666160907161459. Review.

PMID:
27604091

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