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Items: 5


Spindle Assembly Disruption and Cancer Cell Apoptosis with a CLTC-Binding Compound.

Bond MJ, Bleiler M, Harrison LE, Scocchera EW, Nakanishi M, G-Dayanan N, Keshipeddy S, Rosenberg DW, Wright DL, Giardina C.

Mol Cancer Res. 2018 Sep;16(9):1361-1372. doi: 10.1158/1541-7786.MCR-18-0178. Epub 2018 May 16.


Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building Blocks.

G-Dayanandan N, Scocchera EW, Keshipeddy S, Jones HF, Anderson AC, Wright DL.

Org Lett. 2017 Jan 6;19(1):142-145. doi: 10.1021/acs.orglett.6b03438. Epub 2016 Dec 13.


MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates.

Reeve SM, Scocchera EW, G-Dayanadan N, Keshipeddy S, Krucinska J, Hajian B, Ferreira J, Nailor M, Aeschlimann J, Wright DL, Anderson AC.

Cell Chem Biol. 2016 Dec 22;23(12):1458-1467. doi: 10.1016/j.chembiol.2016.11.007. Epub 2016 Dec 8.


Identification of novel compounds that enhance colon cancer cell sensitivity to inflammatory apoptotic ligands.

Chopra AS, Kuratnik A, Scocchera EW, Wright DL, Giardina C.

Cancer Biol Ther. 2013 May;14(5):436-49. doi: 10.4161/cbt.23787. Epub 2013 Feb 1.


Toward new therapeutics for skin and soft tissue infections: propargyl-linked antifolates are potent inhibitors of MRSA and Streptococcus pyogenes.

Viswanathan K, Frey KM, Scocchera EW, Martin BD, Swain Iii PW, Alverson JB, Priestley ND, Anderson AC, Wright DL.

PLoS One. 2012;7(2):e29434. doi: 10.1371/journal.pone.0029434. Epub 2012 Feb 7.

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