Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 66

1.

O Cdc7 kinase where art thou?

Sclafani RA, Hesselberth JR.

Curr Genet. 2018 Jun;64(3):677-680. doi: 10.1007/s00294-017-0782-8. Epub 2017 Nov 13.

2.

Doxycycline-Regulated p16MTS1 Expression Suppresses the Anchorage-Independence and Tumorigenicity of Breast Cancer Cell Lines that Lack Endogenous p16.

Todd MC, Langan TA, Sclafani RA.

J Cancer. 2017 Jan 13;8(2):190-198. doi: 10.7150/jca.15481. eCollection 2017.

3.

The late-annotated small ORF LSO1 is a target gene of the iron regulon of Saccharomyces cerevisiae.

An X, Zhang C, Sclafani RA, Seligman P, Huang M.

Microbiologyopen. 2015 Dec;4(6):941-51. doi: 10.1002/mbo3.303. Epub 2015 Oct 8.

4.

A perspective on chemoprevention by resveratrol in head and neck squamous cell carcinoma.

Shrotriya S, Agarwal R, Sclafani RA.

Adv Exp Med Biol. 2015;815:333-48. doi: 10.1007/978-3-319-09614-8_19. Review.

PMID:
25427916
6.

The role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae.

Brandão LN, Ferguson R, Santoro I, Jinks-Robertson S, Sclafani RA.

Genetics. 2014 Aug;197(4):1111-22. doi: 10.1534/genetics.114.165308. Epub 2014 May 28.

7.

Grape seed extract and resveratrol prevent 4-nitroquinoline 1-oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses.

Shrotriya S, Tyagi A, Deep G, Orlicky DJ, Wisell J, Wang XJ, Sclafani RA, Agarwal R, Agarwal C.

Mol Carcinog. 2015 Apr;54(4):291-300. doi: 10.1002/mc.22099. Epub 2013 Nov 14.

8.

The level of origin firing inversely affects the rate of replication fork progression.

Zhong Y, Nellimoottil T, Peace JM, Knott SR, Villwock SK, Yee JM, Jancuska JM, Rege S, Tecklenburg M, Sclafani RA, Tavaré S, Aparicio OM.

J Cell Biol. 2013 Apr 29;201(3):373-83. doi: 10.1083/jcb.201208060.

9.

Ubiquitin-specific protease 9x deubiquitinates and stabilizes the spinal muscular atrophy protein-survival motor neuron.

Han KJ, Foster DG, Zhang NY, Kanisha K, Dzieciatkowska M, Sclafani RA, Hansen KC, Peng J, Liu CW.

J Biol Chem. 2012 Dec 21;287(52):43741-52. doi: 10.1074/jbc.M112.372318. Epub 2012 Oct 30.

10.

Resveratrol selectively induces DNA Damage, independent of Smad4 expression, in its efficacy against human head and neck squamous cell carcinoma.

Tyagi A, Gu M, Takahata T, Frederick B, Agarwal C, Siriwardana S, Agarwal R, Sclafani RA.

Clin Cancer Res. 2011 Aug 15;17(16):5402-11. doi: 10.1158/1078-0432.CCR-11-1072. Epub 2011 Jun 24.

11.

Grape seed extract upregulates p21 (Cip1) through redox-mediated activation of ERK1/2 and posttranscriptional regulation leading to cell cycle arrest in colon carcinoma HT29 cells.

Kaur M, Tyagi A, Singh RP, Sclafani RA, Agarwal R, Agarwal C.

Mol Carcinog. 2011 Jul;50(7):553-62. doi: 10.1002/mc.20739. Epub 2011 Jan 25.

12.

The yeast Cdc8 exhibits both deoxythymidine monophosphate and diphosphate kinase activities.

Chien CY, Chen BR, Chou CK, Sclafani RA, Su JY.

FEBS Lett. 2009 Jul 7;583(13):2281-6. doi: 10.1016/j.febslet.2009.06.022. Epub 2009 Jun 18.

13.

p21/Cip1 and p27/Kip1 Are essential molecular targets of inositol hexaphosphate for its antitumor efficacy against prostate cancer.

Roy S, Gu M, Ramasamy K, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R.

Cancer Res. 2009 Feb 1;69(3):1166-73. doi: 10.1158/0008-5472.CAN-08-3115. Epub 2009 Jan 27.

14.

Functional conservation of beta-hairpin DNA binding domains in the Mcm protein of Methanobacterium thermoautotrophicum and the Mcm5 protein of Saccharomyces cerevisiae.

Leon RP, Tecklenburg M, Sclafani RA.

Genetics. 2008 Aug;179(4):1757-68. doi: 10.1534/genetics.108.088690. Epub 2008 Jul 27.

15.

p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells.

Roy S, Kaur M, Agarwal C, Tecklenburg M, Sclafani RA, Agarwal R.

Mol Cancer Ther. 2007 Oct;6(10):2696-707.

16.

Structural changes in Mcm5 protein bypass Cdc7-Dbf4 function and reduce replication origin efficiency in Saccharomyces cerevisiae.

Hoang ML, Leon RP, Pessoa-Brandao L, Hunt S, Raghuraman MK, Fangman WL, Brewer BJ, Sclafani RA.

Mol Cell Biol. 2007 Nov;27(21):7594-602. Epub 2007 Aug 27.

17.

Cell cycle regulation of DNA replication.

Sclafani RA, Holzen TM.

Annu Rev Genet. 2007;41:237-80. Review.

18.
19.

Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.

Tyagi A, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R.

Carcinogenesis. 2005 Nov;26(11):1978-87. Epub 2005 Jun 23.

PMID:
15975956
20.
21.

Two heads are better than one: regulation of DNA replication by hexameric helicases.

Sclafani RA, Fletcher RJ, Chen XS.

Genes Dev. 2004 Sep 1;18(17):2039-45. Review. No abstract available.

22.

Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells.

Agarwal C, Singh RP, Dhanalakshmi S, Tyagi AK, Tecklenburg M, Sclafani RA, Agarwal R.

Oncogene. 2003 Nov 13;22(51):8271-82.

PMID:
14614451
23.

Characterization of rat parotid and submandibular acinar cell apoptosis in primary culture.

Limesand KH, Barzen KA, Sanders LA, Sclafani RA, Raynolds MV, Reyland ME, Anderson SM, Quissell DO.

In Vitro Cell Dev Biol Anim. 2003 Mar-Apr;39(3-4):170-7.

24.

The structure and function of MCM from archaeal M. Thermoautotrophicum.

Fletcher RJ, Bishop BE, Leon RP, Sclafani RA, Ogata CM, Chen XS.

Nat Struct Biol. 2003 Mar;10(3):160-7.

PMID:
12548282
26.

p27(Kip1) is important in modulating pulmonary artery smooth muscle cell proliferation.

Fouty BW, Grimison B, Fagan KA, Le Cras TD, Harral JW, Hoedt-Miller M, Sclafani RA, Rodman DM.

Am J Respir Cell Mol Biol. 2001 Nov;25(5):652-8.

PMID:
11713109
27.

Cyclin D1 as a proliferative marker regulating retinoblastoma phosphorylation in mouse lung epithelial cells.

Mamay CL, Schauer IE, Rice PL, McDoniels-Silvers A, Dwyer-Nield LD, You M, Sclafani RA, Malkinson AM.

Cancer Lett. 2001 Jul 26;168(2):165-72. Erratum in: Cancer Lett 2002 Jun 28;180(2):223.

PMID:
11403921
28.
29.

Cdc7p-Dbf4p becomes famous in the cell cycle.

Sclafani RA.

J Cell Sci. 2000 Jun;113 ( Pt 12):2111-7.

30.
31.

Cell cycle control of Cdc7p kinase activity through regulation of Dbf4p stability.

Oshiro G, Owens JC, Shellman Y, Sclafani RA, Li JJ.

Mol Cell Biol. 1999 Jul;19(7):4888-96.

32.
33.

RAD53 regulates DBF4 independently of checkpoint function in Saccharomyces cerevisiae.

Dohrmann PR, Oshiro G, Tecklenburg M, Sclafani RA.

Genetics. 1999 Mar;151(3):965-77.

34.
35.

Oligomers of the Cdc7/Dbf4 protein kinase exist in the yeast cell.

Shellman YG, Schauer IE, Oshiro G, Dohrmann P, Sclafani RA.

Mol Gen Genet. 1998 Sep;259(4):429-36.

PMID:
9790600
36.

A human homolog of the yeast CDC7 gene is overexpressed in some tumors and transformed cell lines.

Hess GF, Drong RF, Weiland KL, Slightom JL, Sclafani RA, Hollingsworth RE.

Gene. 1998 Apr 28;211(1):133-40.

PMID:
9573348
37.

Biphasic regulation of breast cancer cell growth by progesterone: role of the cyclin-dependent kinase inhibitors, p21 and p27(Kip1).

Groshong SD, Owen GI, Grimison B, Schauer IE, Todd MC, Langan TA, Sclafani RA, Lange CA, Horwitz KB.

Mol Endocrinol. 1997 Oct;11(11):1593-607.

PMID:
9328342
38.

Overexpression of the protein kinase Pak1 suppresses yeast DNA polymerase mutations.

Hovland PG, Tecklenberg M, Sclafani RA.

Mol Gen Genet. 1997 Sep;256(1):45-53.

PMID:
9341678
39.

mcm5/cdc46-bob1 bypasses the requirement for the S phase activator Cdc7p.

Hardy CF, Dryga O, Seematter S, Pahl PM, Sclafani RA.

Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3151-5.

40.

Cyclin dependent kinase activating kinases.

Sclafani RA.

Curr Opin Cell Biol. 1996 Dec;8(6):788-94. Review.

PMID:
8939668
41.

Cell cycle control and cancer: lessons from lung cancer.

Sclafani RA, Schauer IE.

J Investig Dermatol Symp Proc. 1996 Apr;1(2):123-7. Review.

PMID:
9627705
42.

Cell cycle regulation of induced mutagenesis in yeast.

Ostroff RM, Sclafani RA.

Mutat Res. 1995 Jul;329(2):143-52.

PMID:
7603496
43.

Cyclin D1 overexpression vs. retinoblastoma inactivation: implications for growth control evasion in non-small cell and small cell lung cancer.

Schauer IE, Siriwardana S, Langan TA, Sclafani RA.

Proc Natl Acad Sci U S A. 1994 Aug 2;91(16):7827-31.

44.

Cdc7 protein kinase for DNA metabolism comes of age.

Sclafani RA, Jackson AL.

Mol Microbiol. 1994 Mar;11(5):805-10. Review.

PMID:
8022258
45.

Yeast pre-meiotic DNA replication utilizes mitotic origin ARS1 independently of CDC7 function.

Hollingsworth RE Jr, Sclafani RA.

Chromosoma. 1993 Jun;102(6):415-20.

PMID:
8365350
46.

Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein.

Jackson AL, Pahl PM, Harrison K, Rosamond J, Sclafani RA.

Mol Cell Biol. 1993 May;13(5):2899-908.

47.

Molecular genetic studies of the Cdc7 protein kinase and induced mutagenesis in yeast.

Hollingsworth RE Jr, Ostroff RM, Klein MB, Niswander LA, Sclafani RA.

Genetics. 1992 Sep;132(1):53-62.

48.
49.

DNA metabolism gene CDC7 from yeast encodes a serine (threonine) protein kinase.

Hollingsworth RE Jr, Sclafani RA.

Proc Natl Acad Sci U S A. 1990 Aug;87(16):6272-6.

50.

Supplemental Content

Loading ...
Support Center