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Items: 4

1.

Fibroblast-specific integrin-alpha V differentially regulates type 17 and type 2 driven inflammation and fibrosis.

Sciurba JC, Gieseck RL, Jiwrajka N, White SD, Karmele EP, Redes J, Vannella KM, Henderson NC, Wynn TA, Hart KM.

J Pathol. 2019 May;248(1):16-29. doi: 10.1002/path.5215. Epub 2019 Jan 24.

PMID:
30536905
2.

Abnormally glycosylated MUC1 establishes a positive feedback circuit of inflammatory cytokines, mediated by NF-κB p65 and EzH2, in colitis-associated cancer.

Cascio S, Faylo JL, Sciurba JC, Xue J, Ranganathan S, Lohmueller JJ, Beatty PL, Finn OJ.

Oncotarget. 2017 Oct 27;8(62):105284-105298. doi: 10.18632/oncotarget.22168. eCollection 2017 Dec 1.

3.

Type 2 immunity is protective in metabolic disease but exacerbates NAFLD collaboratively with TGF-β.

Hart KM, Fabre T, Sciurba JC, Gieseck RL 3rd, Borthwick LA, Vannella KM, Acciani TH, de Queiroz Prado R, Thompson RW, White S, Soucy G, Bilodeau M, Ramalingam TR, Arron JR, Shoukry NH, Wynn TA.

Sci Transl Med. 2017 Jun 28;9(396). pii: eaal3694. doi: 10.1126/scitranslmed.aal3694.

PMID:
28659437
4.

TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma.

Choy DF, Hart KM, Borthwick LA, Shikotra A, Nagarkar DR, Siddiqui S, Jia G, Ohri CM, Doran E, Vannella KM, Butler CA, Hargadon B, Sciurba JC, Gieseck RL, Thompson RW, White S, Abbas AR, Jackman J, Wu LC, Egen JG, Heaney LG, Ramalingam TR, Arron JR, Wynn TA, Bradding P.

Sci Transl Med. 2015 Aug 19;7(301):301ra129. doi: 10.1126/scitranslmed.aab3142.

PMID:
26290411

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