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Items: 1 to 50 of 231

1.

Safety and Adverse Events after Targeted Lung Denervation for Symptomatic Moderate to Severe COPD (AIRFLOW): A Multicenter Randomized Controlled Trial.

Slebos DJ, Shah PL, Herth FJ, Pison C, Schumann C, Hübner RH, Bonta PI, Kessler R, Gesierich W, Darwiche K, Lamprecht B, Perez T, Skowasch D, Deslee G, Marceau A, Sciurba FC, Gosens R, Hartman JE, Srikanthan K, Duller M, Valipour A; AIRFLOW-2 Trial Study Group.

Am J Respir Crit Care Med. 2019 Aug 12. doi: 10.1164/rccm.201903-0624OC. [Epub ahead of print]

PMID:
31404499
2.

Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers.

O'Brien ME, Chandra D, Wilson RC, Karoleski CM, Fuhrman CR, Leader JK, Pu J, Zhang Y, Morris A, Nouraie S, Bon J, Urban Z, Sciurba FC.

Respir Res. 2019 Jun 24;20(1):128. doi: 10.1186/s12931-019-1098-7.

3.

Lung Function, Coronary Artery Disease, and Mortality in HIV.

Chandra D, Gupta A, Fitzpatrick M, Haberlen SA, Neupane M, Leader JK, Kingsley LA, Kleerup E, Budoff MJ, Witt M, Sciurba FC, Post WS, Morris A.

Ann Am Thorac Soc. 2019 Jun;16(6):687-697. doi: 10.1513/AnnalsATS.201807-460OC.

PMID:
31113229
4.

Benralizumab for the Prevention of COPD Exacerbations.

Criner GJ, Celli BR, Brightling CE, Agusti A, Papi A, Singh D, Sin DD, Vogelmeier CF, Sciurba FC, Bafadhel M, Backer V, Kato M, Ramírez-Venegas A, Wei YF, Bjermer L, Shih VH, Jison M, O'Quinn S, Makulova N, Newbold P, Goldman M, Martin UJ; GALATHEA Study Investigators; TERRANOVA Study Investigators.

N Engl J Med. 2019 Sep 12;381(11):1023-1034. doi: 10.1056/NEJMoa1905248. Epub 2019 May 20.

PMID:
31112385
5.

Introducing the New COPD Pocket Consultant Guide App: Can A Digital Approach Improve Care? A Statement of the COPD Foundation.

Thomashow B, Crapo JD, Drummond MB, Han MK, Kalhan R, Malanga E, Malanga V, Mannino DM, Rennard S, Sciurba FC, Willard KS, Wise R, Yawn B.

Chronic Obstr Pulm Dis. 2019 Jul 24;6(3):210-220. doi: 10.15326/jcopdf.6.3.2018.0167.

6.

Subject2Vec: Generative-Discriminative Approach from a Set of Image Patches to a Vector.

Singla S, Gong M, Ravanbakhsh S, Sciurba F, Poczos B, Batmanghelich KN.

Med Image Comput Comput Assist Interv. 2018 Sep;11070:502-510. doi: 10.1007/978-3-030-00928-1_57. Epub 2018 Sep 26.

7.

The Peak Index: Spirometry Metric for Airflow Obstruction Severity and Heterogeneity.

Bhatt SP, Bodduluri S, Raghav V, Bhakta NR, Wilson CG, Kim YI, Eberlein M, Sciurba FC, Han MK, Dransfield MT, Nakhmani A.

Ann Am Thorac Soc. 2019 Aug;16(8):982-989. doi: 10.1513/AnnalsATS.201811-812OC.

PMID:
30865842
8.

Endoscopic Lung Volume Reduction: An Expert Panel Recommendation - Update 2019.

Herth FJF, Slebos DJ, Criner GJ, Valipour A, Sciurba F, Shah PL.

Respiration. 2019;97(6):548-557. doi: 10.1159/000496122. Epub 2019 Mar 5.

PMID:
30836374
9.

Diagnosis and Outpatient Management of Chronic Obstructive Pulmonary Disease: A Review.

Riley CM, Sciurba FC.

JAMA. 2019 Feb 26;321(8):786-797. doi: 10.1001/jama.2019.0131. Review.

PMID:
30806700
10.

Predictors of Response to Endobronchial Coil Therapy in Patients With Advanced Emphysema.

Slebos DJ, Cicenia J, Sciurba FC, Criner GJ, Hartman JE, Garner J, Deslée G, Delage A, Jantz M, Marquette CH, Strange C, Hatipoglu U, Mehta AC, LaPrad AS, Schmid-Bindert G, Herth FJF, Shah PL; RENEW Study Group.

Chest. 2019 May;155(5):928-937. doi: 10.1016/j.chest.2019.02.012. Epub 2019 Feb 21.

PMID:
30797746
11.

Impact of neurological level and spinal curvature on pulmonary function in adults with spina bifida.

Crytzer TM, Cheng YT, Bryner MJ, Wilson Iii R, Sciurba FC, Dicianno BE.

J Pediatr Rehabil Med. 2018;11(4):243-254. doi: 10.3233/PRM-179451.

PMID:
30741703
12.

Reducing Chronic Obstructive Pulmonary Disease Hospital Readmissions. An Official American Thoracic Society Workshop Report.

Press VG, Au DH, Bourbeau J, Dransfield MT, Gershon AS, Krishnan JA, Mularski RA, Sciurba FC, Sullivan J, Feemster LC.

Ann Am Thorac Soc. 2019 Feb;16(2):161-170. doi: 10.1513/AnnalsATS.201811-755WS.

PMID:
30707066
13.

Bronchoscopic device intervention in chronic obstructive pulmonary disease.

Dunlap DG, Semaan R, Riley CM, Sciurba FC.

Curr Opin Pulm Med. 2019 Mar;25(2):201-210. doi: 10.1097/MCP.0000000000000561.

PMID:
30640188
14.

Retraction: Down-regulated peroxisome proliferator-activated receptor γ (PPARγ) in lung epithelial cells promotes a PPARγ agonist-reversible proinflammatory phenotype in chronic obstructive pulmonary disease (COPD).

Lakshmi SP, Reddy AT, Zhang Y, Sciurba FC, Mallampalli RK, Duncan SR, Reddy RC.

J Biol Chem. 2019 Jan 4;294(1):69. doi: 10.1074/jbc.RX118.007042. No abstract available.

15.

New Spirometry Indices for Detecting Mild Airflow Obstruction.

Bhatt SP, Bhakta NR, Wilson CG, Cooper CB, Barjaktarevic I, Bodduluri S, Kim YI, Eberlein M, Woodruff PG, Sciurba FC, Castaldi PJ, Han MK, Dransfield MT, Nakhmani A.

Sci Rep. 2018 Nov 30;8(1):17484. doi: 10.1038/s41598-018-35930-2.

16.

Decreased serum TRAIL is associated with increased mortality in smokers with comorbid emphysema and coronary artery disease.

Ajala O, Zhang Y, Gupta A, Bon J, Sciurba F, Chandra D.

Respir Med. 2018 Dec;145:21-27. doi: 10.1016/j.rmed.2018.10.018. Epub 2018 Oct 19.

PMID:
30509711
17.

The SCFFBXO3 ubiquitin E3 ligase regulates inflammation in atherosclerosis.

Chandra D, Londino J, Alexander S, Bednash JS, Zhang Y, Friedlander RM, Daskivich G, Carlisle DL, Lariviere WR, Nakassa ACI, Ross M, St Croix C, Nyunoya T, Sciurba F, Chen B, Mallampalli RK.

J Mol Cell Cardiol. 2019 Jan;126:50-59. doi: 10.1016/j.yjmcc.2018.11.006. Epub 2018 Nov 16.

PMID:
30448480
18.

Frailty and Clinical Outcomes in Chronic Obstructive Pulmonary Disease.

Kennedy CC, Novotny PJ, LeBrasseur NK, Wise RA, Sciurba FC, Benzo RP.

Ann Am Thorac Soc. 2019 Feb;16(2):217-224. doi: 10.1513/AnnalsATS.201803-175OC.

PMID:
30433830
19.

Endobronchial Coils Versus Lung Volume Reduction Surgery or Medical Therapy for Treatment of Advanced Homogenous Emphysema.

Marchetti N, Kaufman T, Chandra D, Herth FJ, Shah PL, Slebos DJ, Dass C, Bicknell S, Blaas SH, Pfeifer M, Stanzell F, Witt C, Deslee G, Gesierich W, Hetzel M, Kessler R, Leroy S, Hetzel J, Sciurba FC, Criner GJ.

Chronic Obstr Pulm Dis. 2018 Apr 1;5(2):87-96. doi: 10.15326/jcopdf.5.2.2017.0134.

20.

Reply to: The LIBERATE trial: Options to Reduce the Risk of Post-Procedural Pneumothorax and Length of Stay.

Criner GJ, Sue R, Sciurba FC, Slebos DJ.

Am J Respir Crit Care Med. 2018 Sep 19. doi: 10.1164/rccm.201808-1477LE. [Epub ahead of print] No abstract available.

PMID:
30230349
21.

Mixed graphical models for integrative causal analysis with application to chronic lung disease diagnosis and prognosis.

Sedgewick AJ, Buschur K, Shi I, Ramsey JD, Raghu VK, Manatakis DV, Zhang Y, Bon J, Chandra D, Karoleski C, Sciurba FC, Spirtes P, Glymour C, Benos PV.

Bioinformatics. 2019 Apr 1;35(7):1204-1212. doi: 10.1093/bioinformatics/bty769.

PMID:
30192904
22.

The DNA repair transcriptome in severe COPD.

Sauler M, Lamontagne M, Finnemore E, Herazo-Maya JD, Tedrow J, Zhang X, Morneau JE, Sciurba F, Timens W, Paré PD, Lee PJ, Kaminski N, Bossé Y, Gomez JL.

Eur Respir J. 2018 Oct 4;52(4). pii: 1701994. doi: 10.1183/13993003.01994-2017. Print 2018 Oct.

23.

A case series describing common radiographic and pathologic patterns of hard metal pneumoconiosis.

Chiarchiaro J, Tomsic LR, Strock S, Veraldi KL, Nouraie M, Sellares J, Lindell KO, Ortiz LA, Sciurba FC, Kucera RF, Yousem SA, Fuhrman CR, Kass DJ, Gibson KF.

Respir Med Case Rep. 2018 Aug 10;25:124-128. doi: 10.1016/j.rmcr.2018.08.006. eCollection 2018.

24.

Measuring associations between the microbiota and repeated measures of continuous clinical variables using a lasso-penalized generalized linear mixed model.

Tipton L, Cuenco KT, Huang L, Greenblatt RM, Kleerup E, Sciurba F, Duncan SR, Donahoe MP, Morris A, Ghedin E.

BioData Min. 2018 Jun 15;11:12. doi: 10.1186/s13040-018-0173-9. eCollection 2018.

25.

A Multicenter Randomized Controlled Trial of Zephyr Endobronchial Valve Treatment in Heterogeneous Emphysema (LIBERATE).

Criner GJ, Sue R, Wright S, Dransfield M, Rivas-Perez H, Wiese T, Sciurba FC, Shah PL, Wahidi MM, de Oliveira HG, Morrissey B, Cardoso PFG, Hays S, Majid A, Pastis N Jr, Kopas L, Vollenweider M, McFadden PM, Machuzak M, Hsia DW, Sung A, Jarad N, Kornaszewska M, Hazelrigg S, Krishna G, Armstrong B, Shargill NS, Slebos DJ; LIBERATE Study Group.

Am J Respir Crit Care Med. 2018 Nov 1;198(9):1151-1164. doi: 10.1164/rccm.201803-0590OC.

26.

Features of COPD as Predictors of Lung Cancer.

Carr LL, Jacobson S, Lynch DA, Foreman MG, Flenaugh EL, Hersh CP, Sciurba FC, Wilson DO, Sieren JC, Mulhall P, Kim V, Kinsey CM, Bowler RP.

Chest. 2018 Jun;153(6):1326-1335. doi: 10.1016/j.chest.2018.01.049. Epub 2018 Feb 13.

27.

Mepolizumab for Eosinophilic COPD.

Sciurba FC, Bradford ES, Pavord ID.

N Engl J Med. 2018 Feb 15;378(7):681-683. doi: 10.1056/NEJMc1715454. No abstract available.

PMID:
29443666
28.

Radiographic Emphysema, Circulating Bone Biomarkers, and Progressive Bone Mineral Density Loss in Smokers.

Bon J, Zhang Y, Leader JK, Fuhrman C, Perera S, Chandra D, Bertolet M, Diergaarde B, Greenspan SL, Sciurba FC.

Ann Am Thorac Soc. 2018 May;15(5):615-621. doi: 10.1513/AnnalsATS.201709-743OC.

29.

The St. George's Respiratory Questionnaire Appendix to the Food and Drug Administration Draft Guidance on COPD: Why a Small Step Forward Is So Important.

Rennard SI, Merrill D, Tal-Singer R, Sciurba FC.

Chest. 2017 Nov;152(5):914-916. doi: 10.1016/j.chest.2017.07.040. No abstract available.

PMID:
29126533
30.

The Long-Term Oxygen Treatment Trial for Chronic Obstructive Pulmonary Disease: Rationale, Design, and Lessons Learned.

Yusen RD, Criner GJ, Sternberg AL, Au DH, Fuhlbrigge AL, Albert RK, Casaburi R, Stoller JK, Harrington KF, Cooper JAD Jr, Diaz P, Gay S, Kanner R, MacIntyre N, Martinez FJ, Piantadosi S, Sciurba F, Shade D, Stibolt T, Tonascia J, Wise R, Bailey WC; LOTT Research Group *; LOTT Research Group.

Ann Am Thorac Soc. 2018 Jan;15(1):89-101. doi: 10.1513/AnnalsATS.201705-374SD.

31.

Mediastinal and Subcutaneous Chest Fat Are Differentially Associated with Emphysema Progression and Clinical Outcomes in Smokers.

Grace J, Leader JK, Nouraie SM, Pu J, Chandra D, Zhang Y, Sciurba FC, Bon J.

Respiration. 2017;94(6):501-509. doi: 10.1159/000479886. Epub 2017 Sep 15.

32.

Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease.

Pavord ID, Chanez P, Criner GJ, Kerstjens HAM, Korn S, Lugogo N, Martinot JB, Sagara H, Albers FC, Bradford ES, Harris SS, Mayer B, Rubin DB, Yancey SW, Sciurba FC.

N Engl J Med. 2017 Oct 26;377(17):1613-1629. doi: 10.1056/NEJMoa1708208. Epub 2017 Sep 11.

33.

Effect of beta-blockers on exacerbation rate and lung function in chronic obstructive pulmonary disease (COPD).

Duffy S, Marron R, Voelker H, Albert R, Connett J, Bailey W, Casaburi R, Cooper JA Jr, Curtis JL, Dransfield M, Han MK, Make B, Marchetti N, Martinez F, Lazarus S, Niewoehner D, Scanlon PD, Sciurba F, Scharf S, Reed RM, Washko G, Woodruff P, McEvoy C, Aaron S, Sin D, Criner GJ; NIH COPD Clinical Research Network and the Canadian Institutes of Health Research.

Respir Res. 2017 Jun 19;18(1):124. doi: 10.1186/s12931-017-0609-7.

34.

EnRAGEed Kidneys in Chronic Obstructive Pulmonary Disease?

Chandra D, Palevsky P, Sciurba FC.

Am J Respir Crit Care Med. 2017 Jun 1;195(11):1411-1413. doi: 10.1164/rccm.201701-0173ED. No abstract available.

35.

Assessment of coronary artery calcium by chest CT compared with EKG-gated cardiac CT in the multicenter AIDS cohort study.

Chandra D, Gupta A, Leader JK, Fitzpatrick M, Kingsley LA, Kleerup E, Haberlen SA, Budoff MJ, Witt M, Post WS, Sciurba FC, Morris A.

PLoS One. 2017 Apr 28;12(4):e0176557. doi: 10.1371/journal.pone.0176557. eCollection 2017.

36.

Extreme Trait Whole-Genome Sequencing Identifies PTPRO as a Novel Candidate Gene in Emphysema with Severe Airflow Obstruction.

Radder JE, Zhang Y, Gregory AD, Yu S, Kelly NJ, Leader JK, Kaminski N, Sciurba FC, Shapiro SD.

Am J Respir Crit Care Med. 2017 Jul 15;196(2):159-171. doi: 10.1164/rccm.201606-1147OC.

37.

Clinical, physiologic, and radiographic factors contributing to development of hypoxemia in moderate to severe COPD: a cohort study.

Wells JM, Estepar RS, McDonald MN, Bhatt SP, Diaz AA, Bailey WC, Jacobson FL, Dransfield MT, Washko GR, Make BJ, Casaburi R, van Beek EJ, Hoffman EA, Sciurba FC, Crapo JD, Silverman EK, Hersh CP; COPDGene Investigators.

BMC Pulm Med. 2016 Dec 1;16(1):169.

38.

A Randomized Trial of Long-Term Oxygen for COPD with Moderate Desaturation.

Long-Term Oxygen Treatment Trial Research Group, Albert RK, Au DH, Blackford AL, Casaburi R, Cooper JA Jr, Criner GJ, Diaz P, Fuhlbrigge AL, Gay SE, Kanner RE, MacIntyre N, Martinez FJ, Panos RJ, Piantadosi S, Sciurba F, Shade D, Stibolt T, Stoller JK, Wise R, Yusen RD, Tonascia J, Sternberg AL, Bailey W.

N Engl J Med. 2016 Oct 27;375(17):1617-1627.

39.

The 6-Minute-Walk Distance Test as a Chronic Obstructive Pulmonary Disease Stratification Tool. Insights from the COPD Biomarker Qualification Consortium.

Celli B, Tetzlaff K, Criner G, Polkey MI, Sciurba F, Casaburi R, Tal-Singer R, Kawata A, Merrill D, Rennard S; COPD Biomarker Qualification Consortium.

Am J Respir Crit Care Med. 2016 Dec 15;194(12):1483-1493.

40.

Effect of Endobronchial Coils vs Usual Care on Exercise Tolerance in Patients With Severe Emphysema: The RENEW Randomized Clinical Trial.

Sciurba FC, Criner GJ, Strange C, Shah PL, Michaud G, Connolly TA, Deslée G, Tillis WP, Delage A, Marquette CH, Krishna G, Kalhan R, Ferguson JS, Jantz M, Maldonado F, McKenna R, Majid A, Rai N, Gay S, Dransfield MT, Angel L, Maxfield R, Herth FJ, Wahidi MM, Mehta A, Slebos DJ; RENEW Study Research Group.

JAMA. 2016 May 24-31;315(20):2178-89. doi: 10.1001/jama.2016.6261.

41.

Integrated Genomics Reveals Convergent Transcriptomic Networks Underlying Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis.

Kusko RL, Brothers JF 2nd, Tedrow J, Pandit K, Huleihel L, Perdomo C, Liu G, Juan-Guardela B, Kass D, Zhang S, Lenburg M, Martinez F, Quackenbush J, Sciurba F, Limper A, Geraci M, Yang I, Schwartz DA, Beane J, Spira A, Kaminski N.

Am J Respir Crit Care Med. 2016 Oct 15;194(8):948-960.

42.

Airflow Limitation and Endothelial Dysfunction. Unrelated and Independent Predictors of Atherosclerosis.

Chandra D, Gupta A, Strollo PJ Jr, Fuhrman CR, Leader JK, Bon J, Slivka WA, Shoushtari AH, Avolio J, Kip KE, Reis S, Sciurba FC.

Am J Respir Crit Care Med. 2016 Jul 1;194(1):38-47. doi: 10.1164/rccm.201510-2093OC.

43.

Bronchoscopic Lung Volume Reduction in COPD: Lessons in Implementing Clinically Based Precision Medicine.

Sciurba FC, Chandra D, Bon J.

JAMA. 2016 Jan 12;315(2):139-41. doi: 10.1001/jama.2015.17714. No abstract available.

PMID:
26757462
44.

Integrative phenotyping framework (iPF): integrative clustering of multiple omics data identifies novel lung disease subphenotypes.

Kim S, Herazo-Maya JD, Kang DD, Juan-Guardela BM, Tedrow J, Martinez FJ, Sciurba FC, Tseng GC, Kaminski N.

BMC Genomics. 2015 Nov 11;16:924. doi: 10.1186/s12864-015-2170-4.

45.

High Intensity Non-Invasive Positive Pressure Ventilation (HINPPV) for Stable Hypercapnic Chronic Obstructive Pulmonary Disease (COPD) Patients.

Weir M, Marchetti N, Czysz A, Hill N, Sciurba F, Strollo P, Criner GJ.

Chronic Obstr Pulm Dis. 2015 Oct 6;2(4):313-320. doi: 10.15326/jcopdf.2.4.2015.0145.

46.

Determining the Role of Dynamic Hyperinflation in Patients with Severe Chronic Obstructive Pulmonary Disease.

Klooster K, ten Hacken NH, Hartman JE, Sciurba FC, Kerstjens HA, Slebos DJ.

Respiration. 2015;90(4):306-13. doi: 10.1159/000439056. Epub 2015 Sep 10.

47.

Executive Function, Survival, and Hospitalization in Chronic Obstructive Pulmonary Disease. A Longitudinal Analysis of the National Emphysema Treatment Trial (NETT).

Dodd JW, Novotny P, Sciurba FC, Benzo RP; NETT Research Group.

Ann Am Thorac Soc. 2015 Oct;12(10):1473-81. doi: 10.1513/AnnalsATS.201506-373OC.

48.

Rationale and Design of the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis Study. Alpha-1 Protocol.

Strange C, Senior RM, Sciurba F, O'Neal S, Morris A, Wisniewski SR, Bowler R, Hochheiser HS, Becich MJ, Zhang Y, Leader JK, Methé BA, Kaminski N, Sandhaus RA; GRADS Alpha-1 Study Group.

Ann Am Thorac Soc. 2015 Oct;12(10):1551-60. doi: 10.1513/AnnalsATS.201503-143OC.

49.

Rationale for a redundant formulary. The Hawthorne effect and the art of medicine.

Sciurba F, Rennard SI.

Am J Respir Crit Care Med. 2015 Jun 1;191(11):1224-5. doi: 10.1164/rccm.201503-0496ED. No abstract available.

PMID:
26029836
50.

An official American Thoracic Society/European Respiratory Society statement: research questions in COPD.

Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí AA, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, Calverley PM, Casanova C, Clini EM, Cooper CB, Coxson HO, Dusser DJ, Fabbri LM, Fahy B, Ferguson GT, Fisher A, Fletcher MJ, Hayot M, Hurst JR, Jones PW, Mahler DA, Maltais F, Mannino DM, Martinez FJ, Miravitlles M, Meek PM, Papi A, Rabe KF, Roche N, Sciurba FC, Sethi S, Siafakas N, Sin DD, Soriano JB, Stoller JK, Tashkin DP, Troosters T, Verleden GM, Verschakelen J, Vestbo J, Walsh JW, Washko GR, Wise RA, Wouters EF, ZuWallack RL; ATS/ERS Task Force for COPD Research.

Eur Respir Rev. 2015 Jun;24(136):159-72. doi: 10.1183/16000617.00000315. Review.

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