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Items: 6

1.

Mechanistic reconstruction of glycoprotein secretion through monitoring of intracellular N-glycan processing.

Arigoni-Affolter I, Scibona E, Lin CW, Brühlmann D, Souquet J, Broly H, Aebi M.

Sci Adv. 2019 Nov 27;5(11):eaax8930. doi: 10.1126/sciadv.aax8930. eCollection 2019 Nov.

2.

Expansion processes for cell-based therapies.

Scibona E, Morbidelli M.

Biotechnol Adv. 2019 Dec;37(8):107455. doi: 10.1016/j.biotechadv.2019.107455. Epub 2019 Oct 17. Review.

PMID:
31629791
3.

A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of BRAF-mutated Melanoma to MAPK Inhibitors.

Aloia A, Müllhaupt D, Chabbert CD, Eberhart T, Flückiger-Mangual S, Vukolic A, Eichhoff O, Irmisch A, Alexander LT, Scibona E, Frederick DT, Miao B, Tian T, Cheng C, Kwong LN, Wei Z, Sullivan RJ, Boland GM, Herlyn M, Flaherty KT, Zamboni N, Dummer R, Zhang G, Levesque MP, Krek W, Kovacs WJ.

Clin Cancer Res. 2019 Nov 15;25(22):6852-6867. doi: 10.1158/1078-0432.CCR-19-0253. Epub 2019 Aug 2.

PMID:
31375515
4.

Influence of protein/glycan interaction on site-specific glycan heterogeneity.

Losfeld ME, Scibona E, Lin CW, Villiger TK, Gauss R, Morbidelli M, Aebi M.

FASEB J. 2017 Oct;31(10):4623-4635. doi: 10.1096/fj.201700403R. Epub 2017 Jul 5.

PMID:
28679530
5.

Modulation and modeling of monoclonal antibody N-linked glycosylation in mammalian cell perfusion reactors.

Karst DJ, Scibona E, Serra E, Bielser JM, Souquet J, Stettler M, Broly H, Soos M, Morbidelli M, Villiger TK.

Biotechnol Bioeng. 2017 Sep;114(9):1978-1990. doi: 10.1002/bit.26315. Epub 2017 May 23.

PMID:
28409838
6.

Controlling the time evolution of mAb N-linked glycosylation - Part II: Model-based predictions.

Villiger TK, Scibona E, Stettler M, Broly H, Morbidelli M, Soos M.

Biotechnol Prog. 2016 Sep;32(5):1135-1148. doi: 10.1002/btpr.2315. Epub 2016 Jul 1.

PMID:
27273889

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