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Items: 42

1.

Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol.

Teitelbaum AM, McDonald MG, Kowalski JP, Parkinson OT, Scian M, Whittington D, Roellecke K, Hanenberg H, Wiek C, Rettie AE.

J Pharmacol Exp Ther. 2018 Nov 8. pii: jpet.118.249771. doi: 10.1124/jpet.118.249771. [Epub ahead of print]

2.

Gas-Phase Hydrogen/Deuterium Exchange for Distinguishing Isomeric Carbohydrate Ions.

Uppal SS, Beasley SE, Scian M, Guttman M.

Anal Chem. 2017 Apr 18;89(8):4737-4742. doi: 10.1021/acs.analchem.7b00683. Epub 2017 Mar 29.

PMID:
28304155
3.

Membrane Fluidity Modulates Thermal Stability and Ligand Binding of Cytochrome P4503A4 in Lipid Nanodiscs.

McClary WD, Sumida JP, Scian M, Paço L, Atkins WM.

Biochemistry. 2016 Nov 15;55(45):6258-6268. Epub 2016 Nov 1.

4.

The Myeloablative Drug Busulfan Converts Cysteine to Dehydroalanine and Lanthionine in Redoxins.

Scian M, Guttman M, Bouldin SD, Outten CE, Atkins WM.

Biochemistry. 2016 Aug 23;55(33):4720-30. doi: 10.1021/acs.biochem.6b00622. Epub 2016 Aug 11.

5.

Efficient Syntheses of Vitamin K Chain-Shortened Acid Metabolites.

Teitelbaum AM, Scian M, Nelson WL, Rettie AE.

Synthesis (Stuttg). 2015 Apr;47(7):944-948.

6.

Supporting data for characterization of the busulfan metabolite EdAG and the Glutaredoxins that it adducts.

Scian M, Atkins WM.

Data Brief. 2015 Sep 10;5:161-70. doi: 10.1016/j.dib.2015.09.002. eCollection 2015 Dec.

7.

Comparison of epsilon- and delta-class glutathione S-transferases: the crystal structures of the glutathione S-transferases DmGSTE6 and DmGSTE7 from Drosophila melanogaster.

Scian M, Le Trong I, Mazari AM, Mannervik B, Atkins WM, Stenkamp RE.

Acta Crystallogr D Biol Crystallogr. 2015 Oct;71(Pt 10):2089-98. doi: 10.1107/S1399004715013929. Epub 2015 Sep 26.

8.

Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix.

Jennings LK, Storek KM, Ledvina HE, Coulon C, Marmont LS, Sadovskaya I, Secor PR, Tseng BS, Scian M, Filloux A, Wozniak DJ, Howell PL, Parsek MR.

Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11353-8. doi: 10.1073/pnas.1503058112. Epub 2015 Aug 26.

9.

The busulfan metabolite EdAG irreversibly glutathionylates glutaredoxins.

Scian M, Atkins WM.

Arch Biochem Biophys. 2015 Oct 1;583:96-104. doi: 10.1016/j.abb.2015.08.005. Epub 2015 Aug 14.

10.

Development of pyrazolone and isoxazol-5-one cambinol analogues as sirtuin inhibitors.

Mahajan SS, Scian M, Sripathy S, Posakony J, Lao U, Loe TK, Leko V, Thalhofer A, Schuler AD, Bedalov A, Simon JA.

J Med Chem. 2014 Apr 24;57(8):3283-94. doi: 10.1021/jm4018064. Epub 2014 Apr 15.

11.

Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3: metabolite structure, kinetics, inducibility, and interindividual variability.

Wang Z, Wong T, Hashizume T, Dickmann LZ, Scian M, Koszewski NJ, Goff JP, Horst RL, Chaudhry AS, Schuetz EG, Thummel KE.

Endocrinology. 2014 Jun;155(6):2052-63. doi: 10.1210/en.2013-2013. Epub 2014 Mar 18.

12.

Reaction dynamics of ATP hydrolysis catalyzed by P-glycoprotein.

Scian M, Acchione M, Li M, Atkins WM.

Biochemistry. 2014 Feb 18;53(6):991-1000. doi: 10.1021/bi401280v. Epub 2014 Feb 7.

13.

Circular Permutation of the Trp-cage: Fold Rescue upon Addition of a Hydrophobic Staple.

Byrne A, Kier BL, Williams DV, Scian M, Andersen NH.

RSC Adv. 2013 Nov 21;2013(43). doi: 10.1039/C3RA43674H.

14.

The urine microRNA profile may help monitor post-transplant renal graft function.

Maluf DG, Dumur CI, Suh JL, Scian MJ, King AL, Cathro H, Lee JK, Gehrau RC, Brayman KL, Gallon L, Mas VR.

Kidney Int. 2014 Feb;85(2):439-49. doi: 10.1038/ki.2013.338. Epub 2013 Sep 11.

15.

13C structuring shifts for the analysis of model β-hairpins and β-sheets in proteins: diagnostic shifts appear only at the cross-strand H-bonded residues.

Shu I, Scian M, Stewart JM, Kier BL, Andersen NH.

J Biomol NMR. 2013 Aug;56(4):313-29. doi: 10.1007/s10858-013-9749-3. Epub 2013 Jul 14.

PMID:
23851979
16.

Mutational effects on the folding dynamics of a minimized hairpin.

Scian M, Shu I, Olsen KA, Hassam K, Andersen NH.

Biochemistry. 2013 Apr 16;52(15):2556-64. doi: 10.1021/bi400146c. Epub 2013 Apr 5.

17.

MiRNAs in kidney transplantation: potential role as new biomarkers.

Scian MJ, Maluf DG, Mas VR.

Expert Rev Mol Diagn. 2013 Jan;13(1):93-104. doi: 10.1586/erm.12.131. Review.

PMID:
23256706
18.

MicroRNAs as biomarkers in solid organ transplantation.

Mas VR, Dumur CI, Scian MJ, Gehrau RC, Maluf DG.

Am J Transplant. 2013 Jan;13(1):11-9. doi: 10.1111/j.1600-6143.2012.04313.x. Epub 2012 Nov 8. Review.

19.

Stereoselective formation and metabolism of 4-hydroxy-retinoic Acid enantiomers by cytochrome p450 enzymes.

Shimshoni JA, Roberts AG, Scian M, Topletz AR, Blankert SA, Halpert JR, Nelson WL, Isoherranen N.

J Biol Chem. 2012 Dec 7;287(50):42223-32. doi: 10.1074/jbc.M112.404475. Epub 2012 Oct 15.

20.

Identification of biomarkers to assess organ quality and predict posttransplantation outcomes.

Scian MJ, Maluf DG, Archer KJ, Turner SD, Suh JL, David KG, King AL, Posner MP, Brayman KL, Mas VR.

Transplantation. 2012 Oct 27;94(8):851-8. doi: 10.1097/TP.0b013e318263702b.

21.

Crystal and NMR structures of a Trp-cage mini-protein benchmark for computational fold prediction.

Scian M, Lin JC, Le Trong I, Makhatadze GI, Stenkamp RE, Andersen NH.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12521-5. doi: 10.1073/pnas.1121421109. Epub 2012 Jul 16.

22.

Reduced expression of inflammatory genes in deceased donor kidneys undergoing pulsatile pump preservation.

Mas VR, Archer KJ, Dumur CI, Scian MJ, Suh JL, King AL, Wardius ME, Straub JA, Posner MP, Brayman K, Maluf DG.

PLoS One. 2012;7(4):e35526. doi: 10.1371/journal.pone.0035526. Epub 2012 Apr 24.

23.

An inducible cytochrome P450 3A4-dependent vitamin D catabolic pathway.

Wang Z, Lin YS, Zheng XE, Senn T, Hashizume T, Scian M, Dickmann LJ, Nelson SD, Baillie TA, Hebert MF, Blough D, Davis CL, Thummel KE.

Mol Pharmacol. 2012 Apr;81(4):498-509. doi: 10.1124/mol.111.076356. Epub 2011 Dec 28.

24.

Pretransplant transcriptome profiles identify among kidneys with delayed graft function those with poorer quality and outcome.

Mas VR, Scian MJ, Archer KJ, Suh JL, David KG, Ren Q, Gehr TW, King AL, Posner MP, Mueller TF, Maluf DG.

Mol Med. 2011;17(11-12):1311-22. doi: 10.2119/molmed.2011.00159. Epub 2011 Sep 6.

25.

Tracking hydrogen/deuterium exchange at glycan sites in glycoproteins by mass spectrometry.

Guttman M, Scian M, Lee KK.

Anal Chem. 2011 Oct 1;83(19):7492-9. doi: 10.1021/ac201729v. Epub 2011 Sep 6.

26.

MicroRNA profiles in allograft tissues and paired urines associate with chronic allograft dysfunction with IF/TA.

Scian MJ, Maluf DG, David KG, Archer KJ, Suh JL, Wolen AR, Mba MU, Massey HD, King AL, Gehr T, Cotterell A, Posner M, Mas V.

Am J Transplant. 2011 Oct;11(10):2110-22. doi: 10.1111/j.1600-6143.2011.03666.x. Epub 2011 Jul 27.

27.

Gene expression changes are associated with loss of kidney graft function and interstitial fibrosis and tubular atrophy: diagnosis versus prediction.

Scian MJ, Maluf DG, Archer KJ, Suh JL, Massey D, Fassnacht RC, Whitehill B, Sharma A, King A, Gehr T, Cotterell A, Posner MP, Mas V.

Transplantation. 2011 Mar 27;91(6):657-65. doi: 10.1097/TP.0b013e3182094a5a.

PMID:
21242883
28.

β-Sheet 13C structuring shifts appear only at the H-bonded sites of hairpins.

Shu I, Stewart JM, Scian M, Kier BL, Andersen NH.

J Am Chem Soc. 2011 Feb 9;133(5):1196-9. doi: 10.1021/ja1088953. Epub 2011 Jan 7.

29.

Distinctive gene expression profiles characterize donor biopsies from HCV-positive kidney donors.

Mas VR, Archer KJ, Suh L, Scian M, Posner MP, Maluf DG.

Transplantation. 2010 Dec 15;90(11):1172-9. doi: 10.1097/TP.0b013e3181f9ca6c.

PMID:
20935597
30.

Gene expression profiling of peripheral blood leukocytes identifies potential novel biomarkers of chronic obstructive pulmonary disease in current and former smokers.

Edmiston JS, Archer KJ, Scian MJ, Joyce AR, Zedler BK, Murrelle EL.

Biomarkers. 2010 Dec;15(8):715-30. doi: 10.3109/1354750X.2010.512091. Epub 2010 Oct 1.

PMID:
20887155
31.

Molecular pathways involved in loss of graft function in kidney transplant recipients.

Mas VR, Archer KJ, Scian M, Maluf DG.

Expert Rev Mol Diagn. 2010 Apr;10(3):269-84. doi: 10.1586/erm.10.6. Review.

PMID:
20370585
32.

Chemical analysis of cigarette smoke particulate generated in the MSB-01 in vitro whole smoke exposure system.

Scian MJ, Oldham MJ, Miller JH, Kane DB, Edmiston JS, McKinney WJ.

Inhal Toxicol. 2009 Oct;21(12):1040-52. doi: 10.1080/08958370802712705.

PMID:
19772483
33.

Cigarette smoke extract induced protein phosphorylation changes in human microvascular endothelial cells in vitro.

Edmiston JS, Flora JW, Scian MJ, Li G, Rana GS, Langston TB, Sengupta TK, McKinney WJ.

Anal Bioanal Chem. 2009 Jul;394(6):1609-20. doi: 10.1007/s00216-009-2856-z. Epub 2009 May 29.

PMID:
19479242
34.

Characterization of a whole smoke in vitro exposure system (Burghart Mimic Smoker-01).

Scian MJ, Oldham MJ, Kane DB, Edmiston JS, McKinney WJ.

Inhal Toxicol. 2009 Feb;21(3):234-43. doi: 10.1080/08958370802482515 .

PMID:
19016061
35.

Wild-type p53 and p73 negatively regulate expression of proliferation related genes.

Scian MJ, Carchman EH, Mohanraj L, Stagliano KE, Anderson MA, Deb D, Crane BM, Kiyono T, Windle B, Deb SP, Deb S.

Oncogene. 2008 Apr 17;27(18):2583-93. Epub 2007 Nov 5.

PMID:
17982488
36.

Tumor-derived p53 mutants induce NF-kappaB2 gene expression.

Scian MJ, Stagliano KE, Anderson MA, Hassan S, Bowman M, Miles MF, Deb SP, Deb S.

Mol Cell Biol. 2005 Nov;25(22):10097-110.

37.

Backbone dynamics of human parathyroid hormone (1-34): flexibility of the central region under different environmental conditions.

Scian M, Marin M, Bellanda M, Tou L, Alexander JM, Rosenblatt M, Chorev M, Peggion E, Mammi S.

Biopolymers. 2006;84(2):147-60.

PMID:
16123988
38.

Modulation of gene expression by tumor-derived p53 mutants.

Scian MJ, Stagliano KE, Ellis MA, Hassan S, Bowman M, Miles MF, Deb SP, Deb S.

Cancer Res. 2004 Oct 15;64(20):7447-54.

39.

Tumor-derived p53 mutants induce oncogenesis by transactivating growth-promoting genes.

Scian MJ, Stagliano KE, Deb D, Ellis MA, Carchman EH, Das A, Valerie K, Deb SP, Deb S.

Oncogene. 2004 May 27;23(25):4430-43.

PMID:
15077194
40.

Transactivation and transrepression studies with p53.

Scian MJ, Frum R, Deb SP, Deb S.

Methods Mol Biol. 2003;234:93-110.

PMID:
12824527
41.

Hetero-oligomerization does not compromise 'gain of function' of tumor-derived p53 mutants.

Deb D, Scian M, Roth KE, Li W, Keiger J, Chakraborti AS, Deb SP, Deb S.

Oncogene. 2002 Jan 10;21(2):176-89.

42.

Differential modulation of cellular and viral promoters by p73 and p53.

Deb D, Lanyi A, Scian M, Keiger J, Brown DR, Le Roith D, Deb SP, Deb S.

Int J Oncol. 2001 Feb;18(2):401-9.

PMID:
11172610

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