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Items: 11

1.

Safety, pharmacokinetics and pharmacodynamics of the anti-hepcidin Spiegelmer lexaptepid pegol in healthy subjects.

Boyce M, Warrington S, Cortezi B, Zöllner S, Vauléon S, Swinkels DW, Summo L, Schwoebel F, Riecke K.

Br J Pharmacol. 2016 May;173(10):1580-8. doi: 10.1111/bph.13433. Epub 2016 Apr 8.

2.

Effect of the antihepcidin Spiegelmer lexaptepid on inflammation-induced decrease in serum iron in humans.

van Eijk LT, John AS, Schwoebel F, Summo L, Vauléon S, Zöllner S, Laarakkers CM, Kox M, van der Hoeven JG, Swinkels DW, Riecke K, Pickkers P.

Blood. 2014 Oct 23;124(17):2643-6. doi: 10.1182/blood-2014-03-559484. Epub 2014 Aug 27.

3.

Identification and characterization of a mirror-image oligonucleotide that binds and neutralizes sphingosine 1-phosphate, a central mediator of angiogenesis.

Purschke WG, Hoehlig K, Buchner K, Zboralski D, Schwoebel F, Vater A, Klussmann S.

Biochem J. 2014 Aug 15;462(1):153-62. doi: 10.1042/BJ20131422.

4.

Hematopoietic stem and progenitor cell mobilization in mice and humans by a first-in-class mirror-image oligonucleotide inhibitor of CXCL12.

Vater A, Sahlmann J, Kröger N, Zöllner S, Lioznov M, Maasch C, Buchner K, Vossmeyer D, Schwoebel F, Purschke WG, Vonhoff S, Kruschinski A, Hübel K, Humphrey M, Klussmann S, Fliegert F.

Clin Pharmacol Ther. 2013 Jul;94(1):150-7. doi: 10.1038/clpt.2013.58. Epub 2013 Mar 19.

PMID:
23588307
5.

The effects of the anti-hepcidin Spiegelmer NOX-H94 on inflammation-induced anemia in cynomolgus monkeys.

Schwoebel F, van Eijk LT, Zboralski D, Sell S, Buchner K, Maasch C, Purschke WG, Humphrey M, Zöllner S, Eulberg D, Morich F, Pickkers P, Klussmann S.

Blood. 2013 Mar 21;121(12):2311-5. doi: 10.1182/blood-2012-09-456756. Epub 2013 Jan 24.

6.

Optimisation of ITK inhibitors through successive iterative design cycles.

Herdemann M, Weber A, Jonveaux J, Schwoebel F, Stoeck M, Heit I.

Bioorg Med Chem Lett. 2011 Mar 15;21(6):1852-6. doi: 10.1016/j.bmcl.2011.01.035. Epub 2011 Jan 14.

PMID:
21316219
7.

In vivo characterization of the novel imidazopyridine BYK191023 [2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine], a potent and highly selective inhibitor of inducible nitric-oxide synthase.

Lehner MD, Marx D, Boer R, Strub A, Hesslinger C, Eltze M, Ulrich WR, Schwoebel F, Schermuly RT, Barsig J.

J Pharmacol Exp Ther. 2006 Apr;317(1):181-7. Epub 2005 Dec 20.

PMID:
16368897
8.

Early peritoneal macrophage function after laparoscopic surgery compared with laparotomy in a mouse mode.

Moehrlen U, Schwoebel F, Reichmann E, Stauffer U, Gitzelmann CA, Hamacher J.

Surg Endosc. 2005 Jul;19(7):958-63. Epub 2005 May 12. Erratum in: Surg Endosc. 2005 Nov;19(11):1516. Schwöbel, F [corrected to Schwoebel, F].

PMID:
15920692
9.

Quantitative assessment of mouse skin transplant rejection using digital photography.

Schwoebel F, Barsig J, Wendel A, Hamacher J.

Lab Anim. 2005 Apr;39(2):209-14.

PMID:
15901364
10.

Mitogen-activated protein kinase-activated protein kinase 2-deficient mice show increased susceptibility to Listeria monocytogenes infection.

Lehner MD, Schwoebel F, Kotlyarov A, Leist M, Gaestel M, Hartung T.

J Immunol. 2002 May 1;168(9):4667-73.

11.

In vivo and in vitro evidence for extracellular caspase activity released from apoptotic cells.

Hentze H, Schwoebel F, Lund S, Keel M, Ertel W, Wendel A, Jäättelä M, Leist M.

Biochem Biophys Res Commun. 2001 May 25;283(5):1111-7. Erratum in: Biochem Biophys Res Commun 2001 Jul 27;285(4):1076. Kehl M [corrected to Keel M].

PMID:
11355887

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