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Items: 1 to 50 of 137

1.

Putting students at the center: moving beyond time-variable one-size-fits-all medical education to true individualization.

Schwinn DA, Cooper CS, Robillard JE.

Adv Med Educ Pract. 2019 Feb 28;10:109-112. doi: 10.2147/AMEP.S187946. eCollection 2019.

2.

Comprehensive history of 3-year and accelerated US medical school programs: a century in review.

Schwartz CC, Ajjarapu AS, Stamy CD, Schwinn DA.

Med Educ Online. 2018 Dec;23(1):1530557. doi: 10.1080/10872981.2018.1530557.

3.

Time-variable medical education innovation in context.

Stamy CD, Schwartz CC, Phillips DA, Ajjarapu AS, Ferguson KJ, Schwinn DA.

Adv Med Educ Pract. 2018 Jun 20;9:469-481. doi: 10.2147/AMEP.S163984. eCollection 2018.

4.

EDUCATE TO TRANSFORM: THE ART OF DEVELOPING CURIOUS MINDS.

Schwinn DA.

Trans Am Clin Climatol Assoc. 2016;127:259-271.

5.

Alpha1a-Adrenoceptor Genetic Variant Triggers Vascular Smooth Muscle Cell Hyperproliferation and Agonist Induced Hypertrophy via EGFR Transactivation Pathway.

Gradinaru I, Babaeva E, Schwinn DA, Oganesian A.

PLoS One. 2015 Nov 16;10(11):e0142787. doi: 10.1371/journal.pone.0142787. eCollection 2015.

6.

Temporal Dissection of Rate Limiting Transcriptional Events Using Pol II ChIP and RNA Analysis of Adrenergic Stress Gene Activation.

Morris DP, Lei B, Longo LD, Bomsztyk K, Schwinn DA, Michelotti GA.

PLoS One. 2015 Aug 5;10(8):e0134442. doi: 10.1371/journal.pone.0134442. eCollection 2015. Erratum in: PLoS One. 2015;10(10):e0140710.

7.

Research in academic medical centers: two threats to sustainable support.

Levine AS, Alpern RJ, Andrews NC, Antman K, Balser JR, Berg JM, Davis PB, Fitz JG, Golden RN, Goldman L, Jameson JL, Lee VS, Polonsky KS, Rappley MD, Reece EA, Rothman PB, Schwinn DA, Shapiro LJ, Spiegel AM.

Sci Transl Med. 2015 May 27;7(289):289fs22. doi: 10.1126/scitranslmed.aac5200.

PMID:
26019216
8.

Celebrating women in medicine.

Schwinn DA.

Iowa Med. 2013 Sep-Oct;103(5):16. No abstract available.

PMID:
25208449
9.

Team-based patient care. Learning the delicate dance.

Schwinn DA.

Iowa Med. 2014 May-Jun;104(3):19. No abstract available.

PMID:
25174086
10.

Unlocking the great GME bottleneck.

Schwinn DA.

Iowa Med. 2014 Jan-Feb;104(1):22. No abstract available.

PMID:
25167620
11.

Fostering interprofessional teamwork in an academic medical center: Near-peer education for students during gross medical anatomy.

Shields RK, Pizzimenti MA, Dudley-Javoroski S, Schwinn DA.

Anat Sci Educ. 2015 Jul-Aug;8(4):331-7. doi: 10.1002/ase.1466. Epub 2014 May 28.

PMID:
24888728
12.

Alpha1a-adrenoceptor genetic variant induces cardiomyoblast-to-fibroblast-like cell transition via distinct signaling pathways.

Kleine-Brueggeney M, Gradinaru I, Babaeva E, Schwinn DA, Oganesian A.

Cell Signal. 2014 Sep;26(9):1985-97. doi: 10.1016/j.cellsig.2014.05.007. Epub 2014 May 15.

13.

Stimulation of α1a adrenergic receptors induces cellular proliferation or antiproliferative hypertrophy dependent solely on agonist concentration.

Lei B, Schwinn DA, Morris DP.

PLoS One. 2013 Aug 22;8(8):e72430. doi: 10.1371/journal.pone.0072430. eCollection 2013.

14.

Medicine in Iowa--fields of opportunity.

Schwinn DA.

Iowa Med. 2013 May-Jun;103(3):24. No abstract available.

PMID:
25211970
15.

Understanding the TXA seizure connection.

Schwinn DA, Mackensen GB, Brown EN.

J Clin Invest. 2012 Dec;122(12):4339-41. doi: 10.1172/JCI66724. Epub 2012 Nov 26.

16.

Constitutive coupling of a naturally occurring human alpha1a-adrenergic receptor genetic variant to EGFR transactivation pathway.

Oganesian A, Yarov-Yarovoy V, Parks WC, Schwinn DA.

Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19796-801. doi: 10.1073/pnas.1116271108. Epub 2011 Nov 16.

17.

Genetics and patient outcome after cardiac surgery: unravelling translational findings.

Schwinn DA.

Br J Anaesth. 2011 Dec;107(6):839-41. doi: 10.1093/bja/aer347. No abstract available.

18.

Pharmacogenomics of β-adrenergic receptor physiology and response to β-blockade.

von Homeyer P, Schwinn DA.

Anesth Analg. 2011 Dec;113(6):1305-18. doi: 10.1213/ANE.0b013e31822b887e. Epub 2011 Sep 29. Review.

PMID:
21965354
19.

Case 4-2011: malignant hyperthermia in cardiac surgery.

Leff JD, Duran H, Enriquez L, DeRose J, Shore-Lesserson L, Kim JH, Schwinn DA, Podgoreanu MV, Rosenberg H.

J Cardiothorac Vasc Anesth. 2011 Aug;25(4):731-5. doi: 10.1053/j.jvca.2011.01.013. Epub 2011 Mar 21. No abstract available.

PMID:
21420317
20.
21.

Association of the 98T ELAM-1 polymorphism with increased bleeding after cardiac surgery.

Welsby IJ, Podgoreanu MV, Phillips-Bute B, Morris R, Mathew JP, Smith PK, Newman MF, Schwinn DA, Stafford-Smith M; Perioperative Genetics and Safety Outcomes Study Investigative Team.

J Cardiothorac Vasc Anesth. 2010 Jun;24(3):427-33. doi: 10.1053/j.jvca.2009.10.030. Epub 2010 Jan 6.

22.

The United States critical illness and injury trials group: an introduction.

Cobb JP, Cairns CB, Bulger E, Wong HR, Parsons PE, Angus DC, Gentile NT, Hoyt DB, Schwinn DA, Wiener-Kronish JP, Upperman JS.

J Trauma. 2009 Aug;67(2 Suppl):S159-60. doi: 10.1097/TA.0b013e3181ad3473.

PMID:
19667851
23.

Lipid rafts constrain basal alpha(1A)-adrenergic receptor signaling by maintaining receptor in an inactive conformation.

Lei B, Morris DP, Smith MP, Schwinn DA.

Cell Signal. 2009 Oct;21(10):1532-9. doi: 10.1016/j.cellsig.2009.06.001. Epub 2009 Jun 9.

PMID:
19520158
24.

Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion.

Turer AT, Stevens RD, Bain JR, Muehlbauer MJ, van der Westhuizen J, Mathew JP, Schwinn DA, Glower DD, Newgard CB, Podgoreanu MV.

Circulation. 2009 Apr 7;119(13):1736-46. doi: 10.1161/CIRCULATIONAHA.108.816116. Epub 2009 Mar 23.

25.

Pharmacogenomics and perioperative medicine--implications for modern clinical practice.

Kim JH, Schwinn DA, Landau R.

Can J Anaesth. 2008 Dec;55(12):799-806. doi: 10.1007/BF03034050. English, French. No abstract available.

PMID:
19050082
26.

Relationship of genetic variability and depressive symptoms to adverse events after coronary artery bypass graft surgery.

Phillips-Bute B, Mathew JP, Blumenthal JA, Morris RW, Podgoreanu MV, Smith M, Stafford-Smith M, Grocott HP, Schwinn DA, Newman MF; Perioperative Genetics and Safety Outcomes Investigative Team.

Psychosom Med. 2008 Nov;70(9):953-9. doi: 10.1097/PSY.0b013e318187aee6.

27.

Pharmacogenomics and end-organ susceptibility to injury in the perioperative period.

Schwinn DA, Podgoreanu M.

Best Pract Res Clin Anaesthesiol. 2008 Mar;22(1):23-37. Review.

28.

Alpha1-adrenoceptor subtypes and lower urinary tract symptoms.

Schwinn DA, Roehrborn CG.

Int J Urol. 2008 Mar;15(3):193-9. doi: 10.1111/j.1442-2042.2007.01956.x. Review.

29.

Limitations of genetic findings that are not in Hardy-Weinberg equilibrium.

Body SC, Schwinn DA.

Anesthesiology. 2008 Feb;108(2):338; author reply 338-9. doi: 10.1097/01.anes.0000300073.84815.8f. No abstract available.

PMID:
18212593
30.

Understanding the transition to acute illness: the promise of perioperative genomics.

Turer AT, Schwinn DA.

J Cardiovasc Transl Res. 2008 Jun;1(2):171-3. doi: 10.1007/s12265-008-9018-0. Review.

31.

The alpha1a-adrenergic receptor occupies membrane rafts with its G protein effectors but internalizes via clathrin-coated pits.

Morris DP, Lei B, Wu YX, Michelotti GA, Schwinn DA.

J Biol Chem. 2008 Feb 1;283(5):2973-85. Epub 2007 Nov 29.

32.

Alpha-adrenergic mRNA subtype expression in the human nasal turbinate.

Stafford-Smith M, Bartz R, Wilson K, Baraniuk JN, Schwinn DA.

Can J Anaesth. 2007 Jul;54(7):549-55.

PMID:
17602041
33.

Genetic variants in P-selectin and C-reactive protein influence susceptibility to cognitive decline after cardiac surgery.

Mathew JP, Podgoreanu MV, Grocott HP, White WD, Morris RW, Stafford-Smith M, Mackensen GB, Rinder CS, Blumenthal JA, Schwinn DA, Newman MF; PEGASUS Investigative Team.

J Am Coll Cardiol. 2007 May 15;49(19):1934-42. Epub 2007 Apr 30.

34.

Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation.

Michelotti GA, Brinkley DM, Morris DP, Smith MP, Louie RJ, Schwinn DA.

FASEB J. 2007 Jul;21(9):1979-93. Epub 2007 Mar 23.

35.

alpha(1)-Adrenergic receptor antagonists and the iris: new mechanistic insights into floppy iris syndrome.

Schwinn DA, Afshari NA.

Surv Ophthalmol. 2006 Sep-Oct;51(5):501-12. Review.

PMID:
16950249
36.

Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery.

Podgoreanu MV, White WD, Morris RW, Mathew JP, Stafford-Smith M, Welsby IJ, Grocott HP, Milano CA, Newman MF, Schwinn DA; Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team.

Circulation. 2006 Jul 4;114(1 Suppl):I275-81.

37.

Anesthesiology physician scientists in academic medicine: a wake-up call.

Schwinn DA, Balser JR.

Anesthesiology. 2006 Jan;104(1):170-8. Review. No abstract available.

38.

Alpha1-adrenergic antagonists and floppy iris syndrome: tip of the iceberg?

Schwinn DA, Afshari NA.

Ophthalmology. 2005 Dec;112(12):2059-60. No abstract available.

PMID:
16325704
39.

New paradigms in cardiovascular medicine: emerging technologies and practices: perioperative genomics.

Podgoreanu MV, Schwinn DA.

J Am Coll Cardiol. 2005 Dec 6;46(11):1965-77. Epub 2005 Nov 9. Review.

40.

APOE polymorphism is associated with risk of severe sepsis in surgical patients.

Moretti EW, Morris RW, Podgoreanu M, Schwinn DA, Newman MF, Bennett E, Moulin VG, Mba UU, Laskowitz DT; Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team.

Crit Care Med. 2005 Nov;33(11):2521-6.

PMID:
16276176
41.

Characteristics of a human prostate stromal cell line related to its use in a stromal-epithelial coculture model for the study of cancer chemoprevention.

Diaw L, Roth M, Schwinn DA, d'Alelio ME, Green LJ, Tangrea JA.

In Vitro Cell Dev Biol Anim. 2005 May-Jun;41(5-6):142-8.

PMID:
16153146
42.

Neuron specific alpha-adrenergic receptor expression in human cerebellum: implications for emerging cerebellar roles in neurologic disease.

Schambra UB, Mackensen GB, Stafford-Smith M, Haines DE, Schwinn DA.

Neuroscience. 2005;135(2):507-23.

43.

Differential cardiac gene expression during cardiopulmonary bypass: ischemia-independent upregulation of proinflammatory genes.

Podgoreanu MV, Michelotti GA, Sato Y, Smith MP, Lin S, Morris RW, Grocott HP, Mathew JP, Schwinn DA.

J Thorac Cardiovasc Surg. 2005 Aug;130(2):330-9.

44.

Genetic polymorphisms and the risk of stroke after cardiac surgery.

Grocott HP, White WD, Morris RW, Podgoreanu MV, Mathew JP, Nielsen DM, Schwinn DA, Newman MF; Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team.

Stroke. 2005 Sep;36(9):1854-8. Epub 2005 Jul 28.

PMID:
16051899
45.

Evidence that phosphorylation of the RNA polymerase II carboxyl-terminal repeats is similar in yeast and humans.

Morris DP, Michelotti GA, Schwinn DA.

J Biol Chem. 2005 Sep 9;280(36):31368-77. Epub 2005 Jul 12.

46.

The new age of medical genomics.

Schwinn DA, Podgoreanu M.

Br J Anaesth. 2005 Aug;95(2):119-21. No abstract available.

47.

Novel human alpha1a-adrenoceptor single nucleotide polymorphisms alter receptor pharmacology and biological function.

Lei B, Morris DP, Smith MP, Svetkey LP, Newman MF, Rotter JI, Buchanan TA, Beckstrom-Sternberg SM, Green ED, Schwinn DA.

Naunyn Schmiedebergs Arch Pharmacol. 2005 Mar;371(3):229-39. Epub 2005 Mar 10.

48.

Genetic factors contribute to bleeding after cardiac surgery.

Welsby IJ, Podgoreanu MV, Phillips-Bute B, Mathew JP, Smith PK, Newman MF, Schwinn DA, Stafford-Smith M; Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team.

J Thromb Haemost. 2005 Jun;3(6):1206-12. Epub 2005 May 9.

49.

Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery.

Stafford-Smith M, Podgoreanu M, Swaminathan M, Phillips-Bute B, Mathew JP, Hauser EH, Winn MP, Milano C, Nielsen DM, Smith M, Morris R, Newman MF, Schwinn DA; Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team.

Am J Kidney Dis. 2005 Mar;45(3):519-30.

PMID:
15754274
50.

Update on human alpha1-adrenoceptor subtype signaling and genomic organization.

Hawrylyshyn KA, Michelotti GA, Cogé F, Guénin SP, Schwinn DA.

Trends Pharmacol Sci. 2004 Sep;25(9):449-55. Review.

PMID:
15559245

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