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Items: 49

1.

Longitudinal RNA-seq Analysis of the Repeatability of Gene Expression and Splicing in Human Platelets Identifies A Platelet SELP Splice QTL.

Rondina M, Voora D, Simon L, Schwertz H, Harper J, Lee O, Bhatlekar S, Li Q, Eustes AS, Montenont E, Campbell RA, Tolley N, Kosaka Y, Weyrich A, Bray PF, Rowley JW.

Circ Res. 2019 Dec 19. doi: 10.1161/CIRCRESAHA.119.315215. [Epub ahead of print]

PMID:
31852401
2.

Sepsis alters the transcriptional and translational landscape of human and murine platelets.

Middleton EA, Rowley JW, Campbell RA, Grissom CK, Brown SM, Beesley SJ, Schwertz H, Kosaka Y, Manne BK, Krauel K, Tolley ND, Eustes AS, Guo L, Paine R 3rd, Harris ES, Zimmerman GA, Weyrich AS, Rondina MT.

Blood. 2019 Sep 19;134(12):911-923. doi: 10.1182/blood.2019000067. Epub 2019 Jul 31.

PMID:
31366617
3.

Human megakaryocytes possess intrinsic antiviral immunity through regulated induction of IFITM3.

Campbell RA, Schwertz H, Hottz ED, Rowley JW, Manne BK, Washington AV, Hunter-Mellado R, Tolley ND, Christensen M, Eustes AS, Montenont E, Bhatlekar S, Ventrone CH, Kirkpatrick BD, Pierce KK, Whitehead SS, Diehl SA, Bray PF, Zimmerman GA, Kosaka Y, Bozza PT, Bozza FA, Weyrich AS, Rondina MT.

Blood. 2019 May 9;133(19):2013-2026. doi: 10.1182/blood-2018-09-873984. Epub 2019 Feb 5.

PMID:
30723081
4.

Do platelets LINE up for aging?

Schwertz H, Rondina MT.

Aging (Albany NY). 2018 Nov 6;10(11):3054-3055. doi: 10.18632/aging.101636. No abstract available.

5.

Platelets and their Microparticles go hand in hand.

Schwertz H, Rondina MT.

Thromb Res. 2018 Aug;168:164-165. doi: 10.1016/j.thromres.2018.07.018. No abstract available.

PMID:
30060877
6.

Amicus or Adversary Revisited: Platelets in Acute Lung Injury and Acute Respiratory Distress Syndrome.

Middleton EA, Rondina MT, Schwertz H, Zimmerman GA.

Am J Respir Cell Mol Biol. 2018 Jul;59(1):18-35. doi: 10.1165/rcmb.2017-0420TR. Review.

7.

Retinoic acid receptor-α regulates synthetic events in human platelets: reply.

Schwertz H, Rondina MT.

J Thromb Haemost. 2018 May;16(5):1015-1016. doi: 10.1111/jth.13995. Epub 2018 Apr 1. No abstract available.

PMID:
29509307
8.

Endogenous LINE-1 (Long Interspersed Nuclear Element-1) Reverse Transcriptase Activity in Platelets Controls Translational Events Through RNA-DNA Hybrids.

Schwertz H, Rowley JW, Schumann GG, Thorack U, Campbell RA, Manne BK, Zimmerman GA, Weyrich AS, Rondina MT.

Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):801-815. doi: 10.1161/ATVBAHA.117.310552. Epub 2018 Jan 4.

9.

Granzyme A in Human Platelets Regulates the Synthesis of Proinflammatory Cytokines by Monocytes in Aging.

Campbell RA, Franks Z, Bhatnagar A, Rowley JW, Manne BK, Supiano MA, Schwertz H, Weyrich AS, Rondina MT.

J Immunol. 2018 Jan 1;200(1):295-304. doi: 10.4049/jimmunol.1700885. Epub 2017 Nov 22.

10.

Retinoic acid receptor-α regulates synthetic events in human platelets.

Schwertz H, Rowley JW, Zimmerman GA, Weyrich AS, Rondina MT.

J Thromb Haemost. 2017 Dec;15(12):2408-2418. doi: 10.1111/jth.13861. Epub 2017 Nov 1.

11.

Serotype 3 pneumococci sequester platelet-derived human thrombospondin-1 via the adhesin and immune evasion protein Hic.

Binsker U, Kohler TP, Krauel K, Kohler S, Habermeyer J, Schwertz H, Hammerschmidt S.

J Biol Chem. 2017 Apr 7;292(14):5770-5783. doi: 10.1074/jbc.M116.760504. Epub 2017 Feb 16.

12.

Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation.

Yost CC, Schwertz H, Cody MJ, Wallace JA, Campbell RA, Vieira-de-Abreu A, Araujo CV, Schubert S, Harris ES, Rowley JW, Rondina MT, Fulcher JM, Koening CL, Weyrich AS, Zimmerman GA.

J Clin Invest. 2016 Oct 3;126(10):3783-3798. doi: 10.1172/JCI83873. Epub 2016 Sep 6.

13.

Cdkn2a Orchestrates Platelet Production and Reactivity in Atherosclerosis.

Schwertz H, Rondina MT.

Circ Cardiovasc Genet. 2016 Jun;9(3):203-5. doi: 10.1161/CIRCGENETICS.116.001479. No abstract available.

PMID:
27329650
14.

Non-genomic activities of retinoic acid receptor alpha control actin cytoskeletal events in human platelets.

Rondina MT, Freitag M, Pluthero FG, Kahr WH, Rowley JW, Kraiss LW, Franks Z, Zimmerman GA, Weyrich AS, Schwertz H.

J Thromb Haemost. 2016 May;14(5):1082-94. doi: 10.1111/jth.13281. Epub 2016 Mar 22.

15.

Further insights into the anti-PF4/heparin IgM immune response.

Krauel K, Schulze A, Jouni R, Hackbarth C, Hietkamp B, Selleng S, Koster A, Jensch I, van der Linde J, Schwertz H, Bakchoul T, Hundt M, Greinacher A.

Thromb Haemost. 2016 Apr;115(4):752-61. doi: 10.1160/TH15-08-0654. Epub 2015 Oct 15.

PMID:
26467272
16.

Partially desulfated heparin modulates the interaction between anti-protamine/heparin antibodies and platelets.

Jouni R, Zöllner H, Khadour A, Wesche J, Grotevendt A, Brandt S, Delcea M, Krauel K, Schwertz H, Sachs UJ, Greinacher A, Bakchoul T.

Thromb Haemost. 2016 Jan;115(2):324-32. doi: 10.1160/TH15-07-0539. Epub 2015 Oct 1.

PMID:
26423467
17.

Human neutrophil antigen-3a antibodies induce neutrophil stiffening and conformational activation of CD11b without shedding of L-selectin.

Berthold T, Glaubitz M, Muschter S, Groß S, Palankar R, Reil A, Helm CA, Bakchoul T, Schwertz H, Bux J, Greinacher A, Delcea M.

Transfusion. 2015 Dec;55(12):2939-48. doi: 10.1111/trf.13299. Epub 2015 Sep 10.

PMID:
26361072
18.

Pneumococcal Adhesins PavB and PspC Are Important for the Interplay with Human Thrombospondin-1.

Binsker U, Kohler TP, Krauel K, Kohler S, Schwertz H, Hammerschmidt S.

J Biol Chem. 2015 Jun 5;290(23):14542-55. doi: 10.1074/jbc.M114.623876. Epub 2015 Apr 20.

19.

Proteasome function is required for platelet production.

Shi DS, Smith MC, Campbell RA, Zimmerman PW, Franks ZB, Kraemer BF, Machlus KR, Ling J, Kamba P, Schwertz H, Rowley JW, Miles RR, Liu ZJ, Sola-Visner M, Italiano JE Jr, Christensen H, Kahr WH, Li DY, Weyrich AS.

J Clin Invest. 2014 Sep;124(9):3757-66. doi: 10.1172/JCI75247. Epub 2014 Jul 25.

20.

Translational control of JunB, an AP-1 transcription factor, in activated human endothelial cells.

Schmid DI, Schwertz H, Jiang H, Campbell RA, Weyrich AS, McIntyre TM, Zimmerman GA, Kraiss LW.

J Cell Biochem. 2013 Jul;114(7):1519-28. doi: 10.1002/jcb.24493.

21.

Bacteria differentially induce degradation of Bcl-xL, a survival protein, by human platelets.

Kraemer BF, Campbell RA, Schwertz H, Franks ZG, Vieira de Abreu A, Grundler K, Kile BT, Dhakal BK, Rondina MT, Kahr WH, Mulvey MA, Blaylock RC, Zimmerman GA, Weyrich AS.

Blood. 2012 Dec 13;120(25):5014-20. doi: 10.1182/blood-2012-04-420661. Epub 2012 Oct 18.

22.

Platelet mRNA: the meaning behind the message.

Rowley JW, Schwertz H, Weyrich AS.

Curr Opin Hematol. 2012 Sep;19(5):385-91. doi: 10.1097/MOH.0b013e328357010e. Review.

23.

Early storage lesions in apheresis platelets are induced by the activation of the integrin αIIbβ₃ and focal adhesion signaling pathways.

Thiele T, Iuga C, Janetzky S, Schwertz H, Gesell Salazar M, Fürll B, Völker U, Greinacher A, Steil L.

J Proteomics. 2012 Dec 5;76 Spec No.:297-315. doi: 10.1016/j.jprot.2012.04.057. Epub 2012 May 24.

PMID:
22634086
24.

Different mechanisms preserve translation of programmed cell death 8 and JunB in virus-infected endothelial cells.

Jiang H, Schwertz H, Schmid DI, Jones BB, Kriesel J, Martinez ML, Weyrich AS, Zimmerman GA, Kraiss LW.

Arterioscler Thromb Vasc Biol. 2012 Apr;32(4):997-1004. doi: 10.1161/ATVBAHA.112.245324. Epub 2012 Feb 9.

25.

Whole blood flow cytometry measurements of in vivo platelet activation in critically-Ill patients are influenced by variability in blood sampling techniques.

Rondina MT, Grissom CK, Men S, Harris ES, Schwertz H, Zimmerman GA, Weyrich AS.

Thromb Res. 2012 Jun;129(6):729-35. doi: 10.1016/j.thromres.2011.11.031. Epub 2011 Dec 16.

26.

Assessing protein synthesis by platelets.

Schwertz H, Rowley JW, Tolley ND, Campbell RA, Weyrich AS.

Methods Mol Biol. 2012;788:141-53. doi: 10.1007/978-1-61779-307-3_11.

PMID:
22130706
27.

Novel anti-bacterial activities of β-defensin 1 in human platelets: suppression of pathogen growth and signaling of neutrophil extracellular trap formation.

Kraemer BF, Campbell RA, Schwertz H, Cody MJ, Franks Z, Tolley ND, Kahr WH, Lindemann S, Seizer P, Yost CC, Zimmerman GA, Weyrich AS.

PLoS Pathog. 2011 Nov;7(11):e1002355. doi: 10.1371/journal.ppat.1002355. Epub 2011 Nov 10.

28.

Staphylococcus aureus α-toxin triggers the synthesis of B-cell lymphoma 3 by human platelets.

Schubert S, Schwertz H, Weyrich AS, Franks ZG, Lindemann S, Otto M, Behr H, Loppnow H, Schlitt A, Russ M, Presek P, Werdan K, Buerke M.

Toxins (Basel). 2011 Feb;3(2):120-33. doi: 10.3390/toxins3020120. Epub 2011 Jan 28.

29.

Mutations in NBEAL2, encoding a BEACH protein, cause gray platelet syndrome.

Kahr WH, Hinckley J, Li L, Schwertz H, Christensen H, Rowley JW, Pluthero FG, Urban D, Fabbro S, Nixon B, Gadzinski R, Storck M, Wang K, Ryu GY, Jobe SM, Schutte BC, Moseley J, Loughran NB, Parkinson J, Weyrich AS, Di Paola J.

Nat Genet. 2011 Jul 17;43(8):738-40. doi: 10.1038/ng.884.

30.

The septic milieu triggers expression of spliced tissue factor mRNA in human platelets.

Rondina MT, Schwertz H, Harris ES, Kraemer BF, Campbell RA, Mackman N, Grissom CK, Weyrich AS, Zimmerman GA.

J Thromb Haemost. 2011 Apr;9(4):748-58. doi: 10.1111/j.1538-7836.2011.04208.x.

31.

Platelet precursors display bipolar behavior.

Schwertz H, Weyrich AS.

J Cell Biol. 2010 Nov 15;191(4):699-700. doi: 10.1083/jcb.201010082.

32.

Expression of ABC-type transport proteins in human platelets.

Niessen J, Jedlitschky G, Grube M, Kawakami H, Kamiie J, Ohtsuki S, Schwertz H, Bien S, Starke K, Ritter C, Strobel U, Greinacher A, Terasaki T, Kroemer HK.

Pharmacogenet Genomics. 2010 Jun;20(6):396-400. doi: 10.1097/FPC.0b013e32833997b0.

PMID:
20395880
33.

Anucleate platelets generate progeny.

Schwertz H, Köster S, Kahr WH, Michetti N, Kraemer BF, Weitz DA, Blaylock RC, Kraiss LW, Greinacher A, Zimmerman GA, Weyrich AS.

Blood. 2010 May 6;115(18):3801-9. doi: 10.1182/blood-2009-08-239558. Epub 2010 Jan 19.

34.

Fibrinogen selects selectins.

Schwertz H, Zimmerman GA, Weyrich AS.

Blood. 2009 Jul 9;114(2):234. doi: 10.1182/blood-2009-04-216135. No abstract available.

PMID:
19589931
35.

Megakaryocyte impairment by eptifibatide-induced antibodies causes prolonged thrombocytopenia.

Greinacher A, Fuerll B, Zinke H, Müllejans B, Krüger W, Michetti N, Motz W, Schwertz H.

Blood. 2009 Aug 6;114(6):1250-3. doi: 10.1182/blood-2009-02-203034. Epub 2009 May 8.

PMID:
19429867
36.

Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin.

Niessen J, Jedlitschky G, Grube M, Bien S, Schwertz H, Ohtsuki S, Kawakami H, Kamiie J, Oswald S, Starke K, Strobel U, Siegmund W, Rosskopf D, Greinacher A, Terasaki T, Kroemer HK.

Drug Metab Dispos. 2009 May;37(5):1129-37. doi: 10.1124/dmd.108.024570. Epub 2009 Feb 23.

PMID:
19237515
37.

Protein synthesis by platelets: historical and new perspectives.

Weyrich AS, Schwertz H, Kraiss LW, Zimmerman GA.

J Thromb Haemost. 2009 Feb;7(2):241-6. doi: 10.1111/j.1538-7836.2008.03211.x. Epub 2008 Oct 29. Review.

38.

Serine protease inhibitor nafamostat given before reperfusion reduces inflammatory myocardial injury by complement and neutrophil inhibition.

Schwertz H, Carter JM, Russ M, Schubert S, Schlitt A, Buerke U, Schmidt M, Hillen H, Werdan K, Buerke M.

J Cardiovasc Pharmacol. 2008 Aug;52(2):151-60. doi: 10.1097/FJC.0b013e318180188b.

PMID:
18670364
39.

Myocardial ischemia/reperfusion causes VDAC phosphorylation which is reduced by cardioprotection with a p38 MAP kinase inhibitor.

Schwertz H, Carter JM, Abdudureheman M, Russ M, Buerke U, Schlitt A, Müller-Werdan U, Prondzinsky R, Werdan K, Buerke M.

Proteomics. 2007 Dec;7(24):4579-88.

PMID:
18072194
40.

mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets.

Weyrich AS, Denis MM, Schwertz H, Tolley ND, Foulks J, Spencer E, Kraiss LW, Albertine KH, McIntyre TM, Zimmerman GA.

Blood. 2007 Mar 1;109(5):1975-83. Epub 2006 Nov 16.

41.

Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets.

Schwertz H, Tolley ND, Foulks JM, Denis MM, Risenmay BW, Buerke M, Tilley RE, Rondina MT, Harris EM, Kraiss LW, Mackman N, Zimmerman GA, Weyrich AS.

J Exp Med. 2006 Oct 30;203(11):2433-40. Epub 2006 Oct 23.

42.

Proteome analysis of myocardial tissue following ischemia and reperfusion--effects of complement inhibition.

Buerke M, Schwertz H, Längin T, Buerke U, Prondzinsky R, Platsch H, Richert J, Bomm S, Schmidt M, Hillen H, Lindemann S, Blaschke G, Müller-Werdan U, Werdan K.

Biochim Biophys Acta. 2006 Oct;1764(10):1536-45. Epub 2006 May 15.

PMID:
17045855
43.

Intramural delivery of Sirolimus prevents vascular remodeling following balloon injury.

Buerke M, Guckenbiehl M, Schwertz H, Buerke U, Hilker M, Platsch H, Richert J, Bomm S, Zimmerman GA, Lindemann S, Mueller-Werdan U, Werdan K, Darius H, Weyrich AS.

Biochim Biophys Acta. 2007 Jan;1774(1):5-15. Epub 2006 May 19.

44.

Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets.

Denis MM, Tolley ND, Bunting M, Schwertz H, Jiang H, Lindemann S, Yost CC, Rubner FJ, Albertine KH, Swoboda KJ, Fratto CM, Tolley E, Kraiss LW, McIntyre TM, Zimmerman GA, Weyrich AS.

Cell. 2005 Aug 12;122(3):379-91.

45.

Transesophageal echocardiographic image of a thrombus crossing a persistent foramen ovale from the right into the left atrium.

Schwertz H, Prondzinsky R, Hofmann HS, Silber RE, Werdan K, Buerke M.

J Am Soc Echocardiogr. 2005 Mar;18(3):278-9. No abstract available.

PMID:
15746721
46.

[Catecholamine therapy in cardiogenic shock: helpful, useless or dangerous?].

Schwertz H, Müller-Werdan U, Prondzinsky R, Werdan K, Buerke M.

Dtsch Med Wochenschr. 2004 Sep 10;129(37):1925-30. Review. German.

PMID:
15372372
47.

Rapamycin reduces neointima formation during vascular injury.

Hilker M, Buerke M, Guckenbiehl M, Schwertz H, Bühler J, Moersig W, Hake U, Oelert H.

Vasa. 2003 Feb;32(1):10-3.

PMID:
12677758
48.

Two-dimensional analysis of myocardial protein expression following myocardial ischemia and reperfusion in rabbits.

Schwertz H, Längin T, Platsch H, Richert J, Bomm S, Schmidt M, Hillen H, Blaschke G, Meyer J, Darius H, Buerke M.

Proteomics. 2002 Aug;2(8):988-95.

PMID:
12203894
49.

Novel small molecule inhibitor of C1s exerts cardioprotective effects in ischemia-reperfusion injury in rabbits.

Buerke M, Schwertz H, Seitz W, Meyer J, Darius H.

J Immunol. 2001 Nov 1;167(9):5375-80.

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