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Items: 1 to 50 of 97


Long-acting reversible contraception by effervescent microneedle patch.

Li W, Tang J, Terry RN, Li S, Brunie A, Callahan RL, Noel RK, Rodríguez CA, Schwendeman SP, Prausnitz MR.

Sci Adv. 2019 Nov 6;5(11):eaaw8145. doi: 10.1126/sciadv.aaw8145. eCollection 2019 Nov.


Moving RNA interference beyond the liver.

Schwendeman SP.

J Control Release. 2019 Nov 1. pii: S0168-3659(19)30620-0. doi: 10.1016/j.jconrel.2019.10.056. [Epub ahead of print] No abstract available.


Predicting drug release kinetics from nanocarriers inside dialysis bags.

Yu M, Yuan W, Li D, Schwendeman A, Schwendeman SP.

J Control Release. 2019 Oct 16;315:23-30. doi: 10.1016/j.jconrel.2019.09.016. [Epub ahead of print]


Fenretinide, Tocilizumab & Reparixin Provide Multifaceted Disruption of Oral Squamous Cell Carcinoma Stem Cell Properties: Implications for Tertiary chemoprevention.

Mallery SR, Wang D, Santiago B, Pei P, Bissonnette C, Jayawardena JA, Schwendeman SP, Spinney R, Lang J.

Mol Cancer Ther. 2019 Sep 12. pii: molcanther.0361.2019. doi: 10.1158/1535-7163.MCT-19-0361. [Epub ahead of print]


A local combination therapy to inhibit GBM recurrence.

Schwendeman SP.

J Control Release. 2019 Sep 10;309:339-340. doi: 10.1016/j.jconrel.2019.08.012. Epub 2019 Aug 19. No abstract available.


Rapidly separable microneedle patch for the sustained release of a contraceptive.

Li W, Terry RN, Tang J, Feng MR, Schwendeman SP, Prausnitz MR.

Nat Biomed Eng. 2019 Mar;3(3):220-229. doi: 10.1038/s41551-018-0337-4. Epub 2019 Jan 14.


Controlled light-induced gas phase nitric oxide release from S-nitrosothiol-doped silicone rubber films.

Lautner G, Stringer B, Brisbois EJ, Meyerhoff ME, Schwendeman SP.

Nitric Oxide. 2019 May 1;86:31-37. doi: 10.1016/j.niox.2019.01.016. Epub 2019 Feb 5.


Self-healing encapsulation and controlled release of vaccine antigens from PLGA microparticles delivered by microneedle patches.

Mazzara JM, Ochyl LJ, Hong JKY, Moon JJ, Prausnitz MR, Schwendeman SP.

Bioeng Transl Med. 2018 Oct 30;4(1):116-128. doi: 10.1002/btm2.10103. eCollection 2019 Jan.


Reverse Engineering the 1-Month Lupron Depot®.

Zhou J, Hirota K, Ackermann R, Walker J, Wang Y, Choi S, Schwendeman A, Schwendeman SP.

AAPS J. 2018 Oct 2;20(6):105. doi: 10.1208/s12248-018-0253-2.


Guest Editorial Title: Nanomedicine: past, present, and future.

Moon JJ, Schwendeman SP, Schwendeman A.

Adv Drug Deliv Rev. 2018 May;130:1-2. doi: 10.1016/j.addr.2018.07.018. No abstract available.


Battle of GLP-1 delivery technologies.

Yu M, Benjamin MM, Srinivasan S, Morin EE, Shishatskaya EI, Schwendeman SP, Schwendeman A.

Adv Drug Deliv Rev. 2018 May;130:113-130. doi: 10.1016/j.addr.2018.07.009. Epub 2018 Jul 21. Review.


NanoDDS 2017: The 15th International Nanomedicine & Drug Delivery Symposium.

Moon JJ, Hennink WE, Schwendeman SP, Schwendeman A.

J Control Release. 2018 Jul 28;282:1-2. doi: 10.1016/j.jconrel.2018.06.009. No abstract available.


Infliximab Biosimilars in the Age of Personalized Medicine.

Kang J, Pisupati K, Benet A, Ruotolo BT, Schwendeman SP, Schwendeman A.

Trends Biotechnol. 2018 Oct;36(10):987-992. doi: 10.1016/j.tibtech.2018.05.002. Epub 2018 May 31. Review.


In vivo controlled release of fenretinide from long-acting release depots for chemoprevention of oral squamous cell carcinoma recurrence.

Nieto K, Pei P, Wang D, Mallery SR, Schwendeman SP.

Int J Pharm. 2018 Mar 1;538(1-2):48-56. doi: 10.1016/j.ijpharm.2017.11.037. Epub 2017 Nov 21.


Biosimilarity under stress: A forced degradation study of Remicade® and Remsima™.

Pisupati K, Benet A, Tian Y, Okbazghi S, Kang J, Ford M, Saveliev S, Sen KI, Carlson E, Tolbert TJ, Ruotolo BT, Schwendeman SP, Schwendeman A.

MAbs. 2017 Oct;9(7):1197-1209. doi: 10.1080/19420862.2017.1347741. Epub 2017 Aug 8.


Self-encapsulating Poly(lactic-co-glycolic acid) (PLGA) Microspheres for Intranasal Vaccine Delivery.

Bailey BA, Desai KH, Ochyl LJ, Ciotti SM, Moon JJ, Schwendeman SP.

Mol Pharm. 2017 Sep 5;14(9):3228-3237. doi: 10.1021/acs.molpharmaceut.7b00586. Epub 2017 Aug 22.


Toward a Single-Dose Vaccination Strategy with Self-Encapsulating PLGA Microspheres.

Bailey BA, Ochyl LJ, Schwendeman SP, Moon JJ.

Adv Healthc Mater. 2017 Jun;6(12). doi: 10.1002/adhm.201601418. Epub 2017 Apr 3.


A Multidimensional Analytical Comparison of Remicade and the Biosimilar Remsima.

Pisupati K, Tian Y, Okbazghi S, Benet A, Ackermann R, Ford M, Saveliev S, Hosfield CM, Urh M, Carlson E, Becker C, Tolbert TJ, Schwendeman SP, Ruotolo BT, Schwendeman A.

Anal Chem. 2017 May 2;89(9):4838-4846. doi: 10.1021/acs.analchem.6b04436. Epub 2017 Apr 17.


Mechanisms of in vivo release of triamcinolone acetonide from PLGA microspheres.

Doty AC, Weinstein DG, Hirota K, Olsen KF, Ackermann R, Wang Y, Choi S, Schwendeman SP.

J Control Release. 2017 Jun 28;256:19-25. doi: 10.1016/j.jconrel.2017.03.031. Epub 2017 Mar 22.


Mechanistic analysis of triamcinolone acetonide release from PLGA microspheres as a function of varying in vitro release conditions.

Doty AC, Zhang Y, Weinstein DG, Wang Y, Choi S, Qu W, Mittal S, Schwendeman SP.

Eur J Pharm Biopharm. 2017 Apr;113:24-33. doi: 10.1016/j.ejpb.2016.11.008. Epub 2016 Nov 16.


Benefits of Multifaceted Chemopreventives in the Suppression of the Oral Squamous Cell Carcinoma (OSCC) Tumorigenic Phenotype.

Mallery SR, Wang D, Santiago B, Pei P, Schwendeman SP, Nieto K, Spinney R, Tong M, Koutras G, Han B, Holpuch A, Lang J.

Cancer Prev Res (Phila). 2017 Jan;10(1):76-88. doi: 10.1158/1940-6207.CAPR-16-0180. Epub 2016 Oct 18.


Validation of a cage implant system for assessing in vivo performance of long-acting release microspheres.

Doty AC, Hirota K, Olsen KF, Sakamoto N, Ackermann R, Feng MR, Wang Y, Choi S, Qu W, Schwendeman A, Schwendeman SP.

Biomaterials. 2016 Dec;109:88-96. doi: 10.1016/j.biomaterials.2016.07.041. Epub 2016 Aug 18.


Characterizing release mechanisms of leuprolide acetate-loaded PLGA microspheres for IVIVC development I: In vitro evaluation.

Hirota K, Doty AC, Ackermann R, Zhou J, Olsen KF, Feng MR, Wang Y, Choi S, Qu W, Schwendeman AS, Schwendeman SP.

J Control Release. 2016 Dec 28;244(Pt B):302-313. doi: 10.1016/j.jconrel.2016.08.023. Epub 2016 Aug 24.


Reconstructing jaw defects with MSCs and PLGA-encapsulated growth factors.

Tee BC, Desai KG, Kennedy KS, Sonnichsen B, Kim DG, Fields HW, Mallery SR, Schwendeman SP, Sun Z.

Am J Transl Res. 2016 Jun 15;8(6):2693-704. eCollection 2016.


Design of Controlled Release PLGA Microspheres for Hydrophobic Fenretinide.

Zhang Y, Wischke C, Mittal S, Mitra A, Schwendeman SP.

Mol Pharm. 2016 Aug 1;13(8):2622-30. doi: 10.1021/acs.molpharmaceut.5b00961. Epub 2016 Jun 29.


Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma.

Chiang B, Kim YC, Doty AC, Grossniklaus HE, Schwendeman SP, Prausnitz MR.

J Control Release. 2016 Apr 28;228:48-57. doi: 10.1016/j.jconrel.2016.02.041. Epub 2016 Feb 28.


Biodegradable poly(lactic-co-glycolic acid) microspheres loaded with S-nitroso-N-acetyl-D-penicillamine for controlled nitric oxide delivery.

Lautner G, Meyerhoff ME, Schwendeman SP.

J Control Release. 2016 Mar 10;225:133-9. doi: 10.1016/j.jconrel.2015.12.056. Epub 2016 Jan 5.


Feasibility Investigation of Cellulose Polymers for Mucoadhesive Nasal Drug Delivery Applications.

Hansen K, Kim G, Desai KG, Patel H, Olsen KF, Curtis-Fisk J, Tocce E, Jordan S, Schwendeman SP.

Mol Pharm. 2015 Aug 3;12(8):2732-41. doi: 10.1021/acs.molpharmaceut.5b00264. Epub 2015 Jul 24.


Fenretinide Perturbs Focal Adhesion Kinase in Premalignant and Malignant Human Oral Keratinocytes. Fenretinide's Chemopreventive Mechanisms Include ECM Interactions.

Han BB, Li S, Tong M, Holpuch AS, Spinney R, Wang D, Border MB, Liu Z, Sarode S, Pei P, Schwendeman SP, Mallery SR.

Cancer Prev Res (Phila). 2015 May;8(5):419-30. doi: 10.1158/1940-6207.CAPR-14-0418. Epub 2015 Feb 24.


Self-healing of pores in PLGAs.

Huang J, Mazzara JM, Schwendeman SP, Thouless MD.

J Control Release. 2015 May 28;206:20-9. doi: 10.1016/j.jconrel.2015.02.025. Epub 2015 Feb 19.


A biomimetic approach to active self-microencapsulation of proteins in PLGA.

Shah RB, Schwendeman SP.

J Control Release. 2014 Dec 28;196:60-70. doi: 10.1016/j.jconrel.2014.08.029. Epub 2014 Sep 8.


Injectable controlled release depots for large molecules.

Schwendeman SP, Shah RB, Bailey BA, Schwendeman AS.

J Control Release. 2014 Sep 28;190:240-53. doi: 10.1016/j.jconrel.2014.05.057. Epub 2014 Jun 12. Review.


Effect of polymer porosity on aqueous self-healing encapsulation of proteins in PLGA microspheres.

Reinhold SE, Schwendeman SP.

Macromol Biosci. 2013 Dec;13(12):1700-10. doi: 10.1002/mabi.201300323. Epub 2013 Nov 27.


The nature of peptide interactions with acid end-group PLGAs and facile aqueous-based microencapsulation of therapeutic peptides.

Sophocleous AM, Desai KG, Mazzara JM, Tong L, Cheng JX, Olsen KF, Schwendeman SP.

J Control Release. 2013 Dec 28;172(3):662-70. doi: 10.1016/j.jconrel.2013.08.295. Epub 2013 Sep 8.


Healing kinetics of microneedle-formed pores in PLGA films.

Mazzara JM, Balagna MA, Thouless MD, Schwendeman SP.

J Control Release. 2013 Oct 28;171(2):172-7. doi: 10.1016/j.jconrel.2013.06.035. Epub 2013 Jul 5.


Gamma irradiation of active self-healing PLGA microspheres for efficient aqueous encapsulation of vaccine antigens.

Desai KG, Kadous S, Schwendeman SP.

Pharm Res. 2013 Jul;30(7):1768-78. doi: 10.1007/s11095-013-1019-2. Epub 2013 Mar 21.


Active self-healing encapsulation of vaccine antigens in PLGA microspheres.

Desai KG, Schwendeman SP.

J Control Release. 2013 Jan 10;165(1):62-74. doi: 10.1016/j.jconrel.2012.10.012. Epub 2012 Oct 24.


Self-healing microencapsulation of biomacromolecules without organic solvents.

Reinhold SE, Desai KG, Zhang L, Olsen KF, Schwendeman SP.

Angew Chem Int Ed Engl. 2012 Oct 22;51(43):10800-3. doi: 10.1002/anie.201206387. Epub 2012 Sep 26. No abstract available.


The microclimate pH in poly(D,L-lactide-co-hydroxymethyl glycolide) microspheres during biodegradation.

Liu Y, Ghassemi AH, Hennink WE, Schwendeman SP.

Biomaterials. 2012 Oct;33(30):7584-93. doi: 10.1016/j.biomaterials.2012.06.013. Epub 2012 Jul 21.


Vascular endothelial cell-specific microRNA-15a inhibits angiogenesis in hindlimb ischemia.

Yin KJ, Olsen K, Hamblin M, Zhang J, Schwendeman SP, Chen YE.

J Biol Chem. 2012 Aug 3;287(32):27055-64. doi: 10.1074/jbc.M112.364414. Epub 2012 Jun 12.


Minimizing acylation of peptides in PLGA microspheres.

Zhang Y, Schwendeman SP.

J Control Release. 2012 Aug 20;162(1):119-26. doi: 10.1016/j.jconrel.2012.04.022. Epub 2012 Apr 21.


Mapping microclimate pH distribution inside protein-encapsulated PLGA microspheres using confocal laser scanning microscopy.

Liu Y, Schwendeman SP.

Mol Pharm. 2012 May 7;9(5):1342-50. doi: 10.1021/mp200608y. Epub 2012 Apr 23.


Evaluation of a mucoadhesive fenretinide patch for local intraoral delivery: a strategy to reintroduce fenretinide for oral cancer chemoprevention.

Holpuch AS, Phelps MP, Desai KG, Chen W, Koutras GM, Han BB, Warner BM, Pei P, Seghi GA, Tong M, Border MB, Fields HW, Stoner GD, Larsen PE, Liu Z, Schwendeman SP, Mallery SR.

Carcinogenesis. 2012 May;33(5):1098-105. doi: 10.1093/carcin/bgs122. Epub 2012 Mar 15.


Mucoadhesive fenretinide patches for site-specific chemoprevention of oral cancer: enhancement of oral mucosal permeation of fenretinide by coincorporation of propylene glycol and menthol.

Wu X, Desai KG, Mallery SR, Holpuch AS, Phelps MP, Schwendeman SP.

Mol Pharm. 2012 Apr 2;9(4):937-45. doi: 10.1021/mp200655k. Epub 2012 Mar 6.


Optimizing therapeutic efficacy of chemopreventive agents: A critical review of delivery strategies in oral cancer chemoprevention clinical trials.

Holpuch AS, Desai KG, Schwendeman SP, Mallery SR.

J Carcinog. 2011;10:23. doi: 10.4103/1477-3163.85185. Epub 2011 Sep 21.


Development and in vitro-in vivo evaluation of fenretinide-loaded oral mucoadhesive patches for site-specific chemoprevention of oral cancer.

Desai KG, Mallery SR, Holpuch AS, Schwendeman SP.

Pharm Res. 2011 Oct;28(10):2599-609. doi: 10.1007/s11095-011-0489-3. Epub 2011 Jun 15.


Development of PLGA-based injectable delivery systems for hydrophobic fenretinide.

Wischke C, Zhang Y, Mittal S, Schwendeman SP.

Pharm Res. 2010 Oct;27(10):2063-74. doi: 10.1007/s11095-010-0202-y. Epub 2010 Jul 29.


Formulation and in vitro-in vivo evaluation of black raspberry extract-loaded PLGA/PLA injectable millicylindrical implants for sustained delivery of chemopreventive anthocyanins.

Desai KG, Olsen KF, Mallery SR, Stoner GD, Schwendeman SP.

Pharm Res. 2010 Apr;27(4):628-43. doi: 10.1007/s11095-009-0038-5. Epub 2010 Feb 11.


Inhibition of peptide acylation in PLGA microspheres with water-soluble divalent cationic salts.

Zhang Y, Sophocleous AM, Schwendeman SP.

Pharm Res. 2009 Aug;26(8):1986-94. doi: 10.1007/s11095-009-9914-2. Epub 2009 Jun 16.

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