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Association of Platelet-to-Lymphocyte Ratio and Neutrophil-to-Lymphocyte Ratio with the Risk of Thromboembolism and Mortality in Patients with Cancer.

Grilz E, Posch F, Königsbrügge O, Schwarzinger I, Lang IM, Marosi C, Pabinger I, Ay C.

Thromb Haemost. 2018 Nov;118(11):1875-1884. doi: 10.1055/s-0038-1673401. Epub 2018 Oct 8.


Impaired efferocytosis by monocytes in multiple myeloma.

Liang YY, Schwarzinger I, Simonitsch-Klupp I, Agis H, Oehler R.

Oncol Lett. 2018 Jul;16(1):409-416. doi: 10.3892/ol.2018.8620. Epub 2018 May 2.


Major response of PNH to an AML chemotherapy protocol.

Füreder W, Sperr WR, Gleixner K, Thalhammer R, Schwarzinger I, Hoermann G, Kornauth C, Grünberger B, Valent P.

Ann Hematol. 2018 Aug;97(8):1487-1488. doi: 10.1007/s00277-018-3307-8. Epub 2018 Mar 22. No abstract available.


Increased lymphocyte cell size with blastoid morphology associated with splenic rupture following cessation of ibrutinib.

Porpaczy E, Skrabs C, Schwarzinger I, Augustin D, Thalhammer R, Jaeger U.

Br J Haematol. 2018 May;181(4):431. doi: 10.1111/bjh.15134. Epub 2018 Feb 26. No abstract available.


Mortality in patients resuscitated from out-of-hospital cardiac arrest based on automated blood cell count and neutrophil lymphocyte ratio at admission.

Weiser C, Schwameis M, Sterz F, Herkner H, Lang IM, Schwarzinger I, Spiel AO.

Resuscitation. 2017 Jul;116:49-55. doi: 10.1016/j.resuscitation.2017.05.006. Epub 2017 May 2.


The JAK2 blocker TG101209 is a potent inhibitor of clonogenic progenitor cell growth in patients with chronic myeloid leukaemia.

Demyanets S, Jaeger E, Pablik E, Greiner G, Herndlhofer S, Valent P, Schwarzinger I.

Br J Haematol. 2018 Apr;181(1):137-139. doi: 10.1111/bjh.14508. Epub 2017 Feb 21. No abstract available.


Is ruxolitinib a potentially useful drug in hematological malignancies with RAS pathway hyperactivation?

Geissler K, Jäger E, Barna A, Sliwa T, Knöbl P, Schwarzinger I, Gisslinger H, Valent P.

Haematologica. 2016 Dec;101(12):e492. No abstract available.


Evaluation of efficacy of alemtuzumab in 5 patients with aplastic anemia and/or myelodysplastic neoplasm.

Füreder W, Cerny-Reiterer S, Sperr WR, Müllauer L, Jäger E, Schwarzinger I, Geissler K, Valent P.

Wien Klin Wochenschr. 2017 Jun;129(11-12):404-410. doi: 10.1007/s00508-016-1091-9. Epub 2016 Oct 14.


In vitro and in vivo effects of JAK2 inhibition in chronic myelomonocytic leukemia.

Geissler K, Jäger E, Barna A, Sliwa T, Knöbl P, Schwarzinger I, Gisslinger H, Valent P.

Eur J Haematol. 2016 Dec;97(6):562-567. doi: 10.1111/ejh.12773. Epub 2016 Jun 15.


Umbilical Cord Blood Transplantation Is a Feasible Rescue Therapeutic Option for Patients Suffering from Graft Failure after Previous Hematopoietic Stem Cell Transplantation.

Bojic M, Worel N, Sperr WR, Schellongowski P, Wohlfarth P, Schwarzinger I, Mitterbauer-Hohendanner G, Fischer G, Dieckmann KU, Lamm W, Leiner M, Schulenburg A, Mitterbauer M, Greinix HT, Kalhs P, Rabitsch W.

Oncology. 2016;90(3):160-6. doi: 10.1159/000443767. Epub 2016 Feb 13.


The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid.

Steinmetz B, Hackl H, Slabáková E, Schwarzinger I, Smějová M, Spittler A, Arbesu I, Shehata M, Souček K, Wieser R.

Cell Cycle. 2014;13(18):2931-43. doi: 10.4161/15384101.2014.946869. Erratum in: Cell Cycle. 2015;14(11):1759.


Red cell distribution width and other red blood cell parameters in patients with cancer: association with risk of venous thromboembolism and mortality.

Riedl J, Posch F, Königsbrügge O, Lötsch F, Reitter EM, Eigenbauer E, Marosi C, Schwarzinger I, Zielinski C, Pabinger I, Ay C.

PLoS One. 2014 Oct 27;9(10):e111440. doi: 10.1371/journal.pone.0111440. eCollection 2014.


Circulating hematopoietic progenitor cells in essential thrombocythemia versus prefibrotic/early primary myelofibrosis.

Geissler K, Jäger E, Gisslinger B, Thiele J, Schwarzinger I, Gisslinger H.

Am J Hematol. 2014 Dec;89(12):1157-8. doi: 10.1002/ajh.23829. Epub 2014 Aug 27. No abstract available.


FLAG-induced remission in a patient with acute mast cell leukemia (MCL) exhibiting t(7;10)(q22;q26) and KIT D816H.

Valent P, Blatt K, Eisenwort G, Herrmann H, Cerny-Reiterer S, Thalhammer R, Müllauer L, Hoermann G, Sadovnik I, Schwarzinger I, Sperr WR, Mannhalter C, Horny HP.

Leuk Res Rep. 2013 Nov 26;3(1):8-13. doi: 10.1016/j.lrr.2013.11.001. eCollection 2014.


Evaluation of treatment responses and colony-forming progenitor cells in 50 patients with aplastic anemia after immunosuppressive therapy or hematopoietic stem cell transplantation: a single-center experience.

Füreder W, Paulitsch-Buckingham A, Rabitsch W, Jäger E, Schwarzinger I, Sperr WR, Valent P.

Wien Klin Wochenschr. 2014 Feb;126(3-4):119-25. doi: 10.1007/s00508-013-0484-2. Epub 2014 Jan 18.


Association of mean platelet volume with risk of venous thromboembolism and mortality in patients with cancer. Results from the Vienna Cancer and Thrombosis Study (CATS).

Riedl J, Kaider A, Reitter EM, Marosi C, Jäger U, Schwarzinger I, Zielinski C, Pabinger I, Ay C.

Thromb Haemost. 2014 Apr 1;111(4):670-8. doi: 10.1160/TH13-07-0603. Epub 2013 Dec 5.


Endogenous erythroid colony formation in chronic myeloid leukemia: a recurrent finding associated with persistent minimal residual disease under imatinib.

Einwallner E, Jaeger E, Mitterbauer-Hohendanner G, Bilban M, Simonitsch-Klupp I, Steiner I, Pernicka E, Hoermann G, Herndlhofer S, Sillaber C, Valent P, Schwarzinger I.

Stem Cells Dev. 2013 Dec 1;22(23):3043-51. doi: 10.1089/scd.2013.0096. Epub 2013 Sep 4.


EVI1 inhibits apoptosis induced by antileukemic drugs via upregulation of CDKN1A/p21/WAF in human myeloid cells.

Rommer A, Steinmetz B, Herbst F, Hackl H, Heffeter P, Heilos D, Filipits M, Steinleitner K, Hemmati S, Herbacek I, Schwarzinger I, Hartl K, Rondou P, Glimm H, Karakaya K, Krämer A, Berger W, Wieser R.

PLoS One. 2013;8(2):e56308. doi: 10.1371/journal.pone.0056308. Epub 2013 Feb 14.


Lysis matters: red cell lysis with FACS Lyse affects the flow cytometric enumeration of circulating leukemic blasts.

Einwallner E, Subasic A, Strasser A, Augustin D, Thalhammer R, Steiner I, Schwarzinger I.

J Immunol Methods. 2013 Apr 30;390(1-2):127-32. doi: 10.1016/j.jim.2013.01.013. Epub 2013 Feb 4.


Performance evaluation of the Sysmex XE-5000 hematology analyzer for white blood cell analysis in cerebrospinal fluid.

Perné A, Hainfellner JA, Womastek I, Haushofer A, Szekeres T, Schwarzinger I.

Arch Pathol Lab Med. 2012 Feb;136(2):194-8. doi: 10.5858/arpa.2011-0030-OA.


CD34(+)/CD38(-) stem cells in chronic myeloid leukemia express Siglec-3 (CD33) and are responsive to the CD33-targeting drug gemtuzumab/ozogamicin.

Herrmann H, Cerny-Reiterer S, Gleixner KV, Blatt K, Herndlhofer S, Rabitsch W, Jäger E, Mitterbauer-Hohendanner G, Streubel B, Selzer E, Schwarzinger I, Sperr WR, Valent P.

Haematologica. 2012 Feb;97(2):219-26. doi: 10.3324/haematol.2010.035006. Epub 2011 Oct 11.


Idiopathic bone marrow dysplasia of unknown significance (IDUS): definition, pathogenesis, follow up, and prognosis.

Valent P, Jäger E, Mitterbauer-Hohendanner G, Müllauer L, Schwarzinger I, Sperr WR, Thalhammer R, Wimazal F.

Am J Cancer Res. 2011;1(4):531-41. Epub 2010 Mar 16.


Immature and absolute platelet count changes and thrombocytopenia in malignant glioma.

Preusser M, Elandt K, Schwarzinger I, Marosi C, Heinzl H.

Eur J Clin Invest. 2011 May;41(5):539-45. doi: 10.1111/j.1365-2362.2010.02442.x. Epub 2010 Dec 15.


Sequential gene expression profiling during treatment for identification of predictive markers and novel therapeutic targets in chronic lymphocytic leukemia.

Shehata M, Demirtas D, Schnabl S, Hilgarth M, Hubmann R, Fonatsch C, Schwarzinger I, Hopfinger G, Eigenberger K, Heintel D, Porpaczy E, Vanura K, Hauswirth A, Schwarzmeier JD, Gaiger A, Stilgenbauer S, Hallek M, Bilban M, Jäger U.

Leukemia. 2010 Dec;24(12):2122-7. doi: 10.1038/leu.2010.220. Epub 2010 Oct 22. No abstract available.


Interference of Mycoplasma infection in a gene expression study: it was the environment and not the gene.

Hoermann G, Spergser J, Einwallner E, Makristathis A, Perne A, Willinger B, Schwarzinger I.

Appl Environ Microbiol. 2010 Dec;76(23):7867-9. doi: 10.1128/AEM.01265-10. Epub 2010 Oct 1. Erratum in: Appl Environ Microbiol. 2011 Feb;77(3):1151.


Improved outcome in patients with chronic myelogenous leukemia after allogeneic hematopoietic stem cell transplantation over the past 25 years: a single-center experience.

Boehm A, Walcherberger B, Sperr WR, Wöhrer S, Dieckmann K, Rosenmayr A, Pernicka E, Fischer G, Worel N, Mitterbauer G, Schwarzinger I, Mitterbauer M, Haas OA, Lechner K, Hinterberger W, Valent P, Greinix HT, Rabitsch W, Kalhs P.

Biol Blood Marrow Transplant. 2011 Jan;17(1):133-40. doi: 10.1016/j.bbmt.2010.06.019. Epub 2010 Jul 1.


Cardiac glycosides induce cell death in human cells by inhibiting general protein synthesis.

Perne A, Muellner MK, Steinrueck M, Craig-Mueller N, Mayerhofer J, Schwarzinger I, Sloane M, Uras IZ, Hoermann G, Nijman SM, Mayerhofer M.

PLoS One. 2009 Dec 16;4(12):e8292. doi: 10.1371/journal.pone.0008292.


High platelet count associated with venous thromboembolism in cancer patients: results from the Vienna Cancer and Thrombosis Study (CATS).

Simanek R, Vormittag R, Ay C, Alguel G, Dunkler D, Schwarzinger I, Steger G, Jaeger U, Zielinski C, Pabinger I.

J Thromb Haemost. 2010 Jan;8(1):114-20. doi: 10.1111/j.1538-7836.2009.03680.x. Epub 2009 Nov 2.


Inducible expression of EVI1 in human myeloid cells causes phenotypes consistent with its role in myelodysplastic syndromes.

Konrad TA, Karger A, Hackl H, Schwarzinger I, Herbacek I, Wieser R.

J Leukoc Biol. 2009 Oct;86(4):813-22. doi: 10.1189/jlb.0109042. Epub 2009 Jul 15.


Gene expression signature of chronic lymphocytic leukaemia with Trisomy 12.

Porpaczy E, Bilban M, Heinze G, Gruber M, Vanura K, Schwarzinger I, Stilgenbauer S, Streubel B, Fonatsch C, Jaeger U.

Eur J Clin Invest. 2009 Jul;39(7):568-75. doi: 10.1111/j.1365-2362.2009.02146.x. Epub 2009 Apr 30.


Autoimmune conditions and chronic infections in chronic lymphocytic leukemia patients at diagnosis are associated with unmutated IgVH genes.

Vanura K, Le T, Esterbauer H, Späth F, Porpaczy E, Shehata M, Eigenberger K, Hauswirth A, Skrabs C, Krömer E, Schwarzinger I, Streubel B, Steininger C, Fonatsch C, Stilgenbauer S, Wagner O, Gaiger A, Jäger U.

Haematologica. 2008 Dec;93(12):1912-6. doi: 10.3324/haematol.12955. Epub 2008 Oct 6.


Dasatinib inhibits progenitor cell proliferation from polycythaemia vera.

Wappl M, Jaeger E, Streubel B, Gisslinger H, Schwarzinger I, Valent P, Oehler L.

Eur J Clin Invest. 2008 Aug;38(8):578-84. doi: 10.1111/j.1365-2362.2008.01982.x.


Systemic lupus erythematosus patients exhibit functional deficiencies of endothelial progenitor cells.

Grisar J, Steiner CW, Bonelli M, Karonitsch T, Schwarzinger I, Weigel G, Steiner G, Smolen JS.

Rheumatology (Oxford). 2008 Oct;47(10):1476-83. doi: 10.1093/rheumatology/ken286. Epub 2008 Jul 26.


Unique effects of KIT D816V in BaF3 cells: induction of cluster formation, histamine synthesis, and early mast cell differentiation antigens.

Mayerhofer M, Gleixner KV, Hoelbl A, Florian S, Hoermann G, Aichberger KJ, Bilban M, Esterbauer H, Krauth MT, Sperr WR, Longley JB, Kralovics R, Moriggl R, Zappulla J, Liblau RS, Schwarzinger I, Sexl V, Sillaber C, Valent P.

J Immunol. 2008 Apr 15;180(8):5466-76.


Prognostic significance of serial determinations of lactate dehydrogenase (LDH) in the follow-up of patients with myelodysplastic syndromes.

Wimazal F, Sperr WR, Kundi M, Vales A, Fonatsch C, Thalhammer-Scherrer R, Schwarzinger I, Valent P.

Ann Oncol. 2008 May;19(5):970-6. doi: 10.1093/annonc/mdm595. Epub 2008 Feb 13.


The JAK2V617F mutation: no impact on circulating hematopoietic progenitors in myeloproliferative disorders.

Wappl M, Jaeger E, Kusec R, Schwarzinger I, Geissler K, Oehler L.

Ann Hematol. 2008 Jun;87(6):509-11. doi: 10.1007/s00277-007-0428-x. Epub 2008 Jan 5. No abstract available.


Targeting of heat shock protein 32 (Hsp32)/heme oxygenase-1 (HO-1) in leukemic cells in chronic myeloid leukemia: a novel approach to overcome resistance against imatinib.

Mayerhofer M, Gleixner KV, Mayerhofer J, Hoermann G, Jaeger E, Aichberger KJ, Ott RG, Greish K, Nakamura H, Derdak S, Samorapoompichit P, Pickl WF, Sexl V, Esterbauer H, Schwarzinger I, Sillaber C, Maeda H, Valent P.

Blood. 2008 Feb 15;111(4):2200-10. Epub 2007 Nov 16.


Liposomal cytarabine for treatment of myeloid central nervous system relapse in chronic myeloid leukaemia occurring during imatinib therapy.

Aichberger KJ, Herndlhofer S, Agis H, Sperr WR, Esterbauer H, Rabitsch W, Knöbl P, Haas OA, Thalhammer R, Schwarzinger I, Sillaber C, Jäger U, Valent P.

Eur J Clin Invest. 2007 Oct;37(10):808-13. Epub 2007 Aug 28.


Overexpression of the paternally expressed gene 10 (PEG10) from the imprinted locus on chromosome 7q21 in high-risk B-cell chronic lymphocytic leukemia.

Kainz B, Shehata M, Bilban M, Kienle D, Heintel D, Krömer-Holzinger E, Le T, Kröber A, Heller G, Schwarzinger I, Demirtas D, Chott A, Döhner H, Zöchbauer-Müller S, Fonatsch C, Zielinski C, Stilgenbauer S, Gaiger A, Wagner O, Jäger U.

Int J Cancer. 2007 Nov 1;121(9):1984-93.


Idiopathic cytopenia of undetermined significance (ICUS) versus low risk MDS: the diagnostic interface.

Wimazal F, Fonatsch C, Thalhammer R, Schwarzinger I, Müllauer L, Sperr WR, Bennett JM, Valent P.

Leuk Res. 2007 Nov;31(11):1461-8. Epub 2007 May 16.


Endothelial progenitor cells in active rheumatoid arthritis: effects of tumour necrosis factor and glucocorticoid therapy.

Grisar J, Aletaha D, Steiner CW, Kapral T, Steiner S, Säemann M, Schwarzinger I, Buranyi B, Steiner G, Smolen JS.

Ann Rheum Dis. 2007 Oct;66(10):1284-8. Epub 2007 Feb 9.


In vivo effects of imatinib mesylate on human haematopoietic progenitor cells.

Agis H, Jaeger E, Doninger B, Sillaber C, Marosi C, Drach J, Schwarzinger I, Valent P, Oehler L.

Eur J Clin Invest. 2006 Jun;36(6):402-8.


Remission of pure red cell aplasia in T-cell receptor gammadelta-large granular lymphocyte leukemia after therapy with low-dose alemtuzumab.

Schützinger C, Gaiger A, Thalhammer R, Vesely M, Fritsche-Polanz R, Schwarzinger I, Ohler L, Simonitsch-Klupp I, Reinhard F, Jäger U.

Leukemia. 2005 Nov;19(11):2005-8. No abstract available.


An unusual case of myelodysplastic syndrome with prolonged clonal stability, indolent clinical course over a decade, and spontaneous regression of AML in the terminal phase.

Sonneck K, Mannhalter C, Krauth MT, Sperr WR, Schwarzinger I, Fonatsch C, Haas O, Geissler K, Valent P.

Eur J Haematol. 2005 Jul;75(1):73-7.


Limited value of FLT3 mRNA expression in the bone marrow for prognosis and monitoring of patients with acute myeloid leukemia.

Kainz B, Fonatsch C, Schwarzinger I, Sperr WR, Jäger U, Gaiger A.

Haematologica. 2005 May;90(5):695-6.


Association of neutrophils and future cardiovascular events in patients with peripheral artery disease.

Haumer M, Amighi J, Exner M, Mlekusch W, Sabeti S, Schlager O, Schwarzinger I, Wagner O, Minar E, Schillinger M.

J Vasc Surg. 2005 Apr;41(4):610-7.


High expression of lipoprotein lipase in poor risk B-cell chronic lymphocytic leukemia.

Heintel D, Kienle D, Shehata M, Kröber A, Kroemer E, Schwarzinger I, Mitteregger D, Le T, Gleiss A, Mannhalter C, Chott A, Schwarzmeier J, Fonatsch C, Gaiger A, Döhner H, Stilgenbauer S, Jäger U; CLL Study Group.

Leukemia. 2005 Jul;19(7):1216-23.


Depletion of endothelial progenitor cells in the peripheral blood of patients with rheumatoid arthritis.

Grisar J, Aletaha D, Steiner CW, Kapral T, Steiner S, Seidinger D, Weigel G, Schwarzinger I, Wolozcszuk W, Steiner G, Smolen JS.

Circulation. 2005 Jan 18;111(2):204-11. Epub 2005 Jan 10.


Highly refractory acute myeloid leukemia.

Füreder W, Filipits M, Sperr WR, Kainz B, Jäger U, Fonatsch C, Schwarzinger I, Haas OA, Pirker R, Lechner K.

Wien Klin Wochenschr. 2004 Aug 31;116(15-16):561-4.


Lymphoma-specific genetic aberrations in microvascular endothelial cells in B-cell lymphomas.

Streubel B, Chott A, Huber D, Exner M, Jäger U, Wagner O, Schwarzinger I.

N Engl J Med. 2004 Jul 15;351(3):250-9.

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